Mus musculus

0 known processes

Tmem45a

transmembrane protein 45a

(Aliases: p19.5,C630002M10Rik,M32486)

Tmem45a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
extracellular structure organization GO:0043062 148 0.365
extrinsic apoptotic signaling pathway GO:0097191 126 0.258
collagen fibril organization GO:0030199 32 0.243
extracellular matrix organization GO:0030198 147 0.225
skeletal system development GO:0001501 356 0.222
response to organic cyclic compound GO:0014070 198 0.167
apoptotic signaling pathway GO:0097190 306 0.158
ossification GO:0001503 216 0.111
negative regulation of apoptotic signaling pathway GO:2001234 104 0.103
regulation of apoptotic signaling pathway GO:2001233 197 0.097
cell matrix adhesion GO:0007160 68 0.095
appendage development GO:0048736 166 0.085
signal transduction in absence of ligand GO:0038034 55 0.082
heart morphogenesis GO:0003007 178 0.081
cartilage development GO:0051216 140 0.072
cellular ketone metabolic process GO:0042180 84 0.069
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.067
cardiac muscle tissue development GO:0048738 130 0.064
bone development GO:0060348 120 0.062
blood vessel morphogenesis GO:0048514 285 0.061
skeletal system morphogenesis GO:0048705 203 0.061
negative regulation of molecular function GO:0044092 258 0.061
peptidyl amino acid modification GO:0018193 336 0.059
connective tissue development GO:0061448 179 0.058
regulation of tooth mineralization GO:0070170 2 0.058
cell adhesion GO:0007155 329 0.058
cellular amino acid metabolic process GO:0006520 103 0.055
response to epidermal growth factor GO:0070849 4 0.053
regulation of organelle organization GO:0033043 289 0.052
monocarboxylic acid metabolic process GO:0032787 191 0.051
skin development GO:0043588 220 0.051
negative regulation of cell migration GO:0030336 59 0.049
cardiac chamber development GO:0003205 108 0.049
muscle tissue development GO:0060537 308 0.048
cardiac chamber morphogenesis GO:0003206 93 0.048
response to growth factor GO:0070848 198 0.048
multicellular organismal homeostasis GO:0048871 164 0.048
small gtpase mediated signal transduction GO:0007264 97 0.048
chondrocyte development GO:0002063 24 0.048
organ growth GO:0035265 117 0.046
engulfment of apoptotic cell GO:0043652 3 0.045
regulation of cell adhesion GO:0030155 154 0.045
limb morphogenesis GO:0035108 149 0.045
limb development GO:0060173 166 0.044
protein maturation GO:0051604 176 0.044
fibril organization GO:0097435 2 0.043
regulation of cell motility GO:2000145 236 0.043
regulation of cellular ketone metabolic process GO:0010565 66 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
positive regulation of cell death GO:0010942 224 0.041
regulation of cellular component biogenesis GO:0044087 181 0.041
ameboidal type cell migration GO:0001667 128 0.040
regulation of system process GO:0044057 200 0.040
glycoprotein metabolic process GO:0009100 116 0.039
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.039
cell substrate adhesion GO:0031589 130 0.038
actin cytoskeleton organization GO:0030036 220 0.036
epithelial cell proliferation GO:0050673 174 0.036
oxidation reduction process GO:0055114 342 0.035
mesenchyme development GO:0060485 152 0.033
embryonic organ morphogenesis GO:0048562 276 0.032
cytokine production GO:0001816 319 0.031
regulation of cell size GO:0008361 72 0.031
response to organonitrogen compound GO:0010243 246 0.031
ear development GO:0043583 200 0.030
multi multicellular organism process GO:0044706 109 0.030
trabecula morphogenesis GO:0061383 40 0.030
blood circulation GO:0008015 195 0.029
protein catabolic process GO:0030163 221 0.029
cardiac ventricle development GO:0003231 83 0.029
telencephalon development GO:0021537 186 0.029
negative regulation of protein processing GO:0010955 79 0.029
extracellular fibril organization GO:0043206 2 0.029
rho protein signal transduction GO:0007266 32 0.028
sensory perception of mechanical stimulus GO:0050954 107 0.028
negative regulation of cell proliferation GO:0008285 296 0.028
proteoglycan metabolic process GO:0006029 38 0.027
regulation of reactive oxygen species metabolic process GO:2000377 40 0.027
developmental maturation GO:0021700 193 0.027
negative regulation of hydrolase activity GO:0051346 71 0.027
protein hydroxylation GO:0018126 4 0.027
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.027
placenta development GO:0001890 140 0.027
regulation of cell migration GO:0030334 219 0.027
regulation of organ morphogenesis GO:2000027 144 0.026
regulation of membrane potential GO:0042391 192 0.026
regulation of defense response GO:0031347 233 0.026
negative regulation of cell motility GO:2000146 61 0.026
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.026
trabecula formation GO:0060343 24 0.026
epidermis development GO:0008544 187 0.026
muscle tissue morphogenesis GO:0060415 53 0.026
striated muscle tissue development GO:0014706 293 0.025
digestive tract development GO:0048565 190 0.025
mesoderm development GO:0007498 100 0.025
head morphogenesis GO:0060323 34 0.025
regulation of cell cycle GO:0051726 281 0.025
cell type specific apoptotic process GO:0097285 268 0.025
renal system development GO:0072001 225 0.025
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.025
inflammatory response GO:0006954 244 0.025
gland development GO:0048732 330 0.025
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.025
stem cell differentiation GO:0048863 268 0.025
negative regulation of cellular component organization GO:0051129 194 0.024
carboxylic acid transport GO:0046942 100 0.024
bone trabecula morphogenesis GO:0061430 12 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
wound healing GO:0042060 157 0.024
protein processing GO:0016485 163 0.024
circulatory system process GO:0003013 197 0.024
wnt signaling pathway GO:0016055 188 0.023
neuronal action potential GO:0019228 54 0.023
response to acid chemical GO:0001101 111 0.023
lipid biosynthetic process GO:0008610 179 0.023
negative regulation of cell development GO:0010721 169 0.023
cell growth GO:0016049 130 0.023
cellular response to cytokine stimulus GO:0071345 189 0.022
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.022
morphogenesis of a branching structure GO:0001763 203 0.022
bone trabecula formation GO:0060346 9 0.022
tissue homeostasis GO:0001894 115 0.022
regulation of hydrolase activity GO:0051336 246 0.022
angiogenesis GO:0001525 201 0.022
positive regulation of programmed cell death GO:0043068 218 0.021
positive regulation of vesicle fusion GO:0031340 2 0.021
regulation of cell growth GO:0001558 91 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
epithelial tube morphogenesis GO:0060562 303 0.021
cellular amine metabolic process GO:0044106 44 0.021
response to oxidative stress GO:0006979 123 0.021
amine metabolic process GO:0009308 45 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
sensory organ morphogenesis GO:0090596 242 0.021
cardiac muscle tissue morphogenesis GO:0055008 44 0.020
cardiac muscle contraction GO:0060048 32 0.020
regulation of homeostatic process GO:0032844 182 0.020
asymmetric stem cell division GO:0098722 3 0.020
innate immune response GO:0045087 157 0.020
organic acid transport GO:0015849 101 0.020
fatty acid metabolic process GO:0006631 121 0.020
cardiac septum morphogenesis GO:0060411 46 0.019
regulation of cell cycle process GO:0010564 160 0.019
response to extracellular stimulus GO:0009991 127 0.019
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.019
regulation of fat cell differentiation GO:0045598 81 0.019
negative regulation of cell adhesion GO:0007162 45 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
metal ion homeostasis GO:0055065 189 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
regulation of body fluid levels GO:0050878 162 0.018
cellular response to organic cyclic compound GO:0071407 87 0.018
pallium development GO:0021543 120 0.018
negative regulation of bmp signaling pathway GO:0030514 35 0.018
negative regulation of tooth mineralization GO:0070171 1 0.018
bone morphogenesis GO:0060349 78 0.018
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.018
respiratory tube development GO:0030323 167 0.018
mitotic cell cycle GO:0000278 195 0.018
cellular lipid metabolic process GO:0044255 323 0.018
morphogenesis of embryonic epithelium GO:0016331 159 0.018
elastic fiber assembly GO:0048251 4 0.018
macromolecule catabolic process GO:0009057 281 0.018
heart contraction GO:0060047 93 0.017
regulation of cytokine production GO:0001817 266 0.017
positive regulation of cellular component biogenesis GO:0044089 94 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
mesonephros development GO:0001823 97 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
digestive system development GO:0055123 200 0.017
appendage morphogenesis GO:0035107 149 0.017
cardiac ventricle morphogenesis GO:0003208 50 0.017
single organismal cell cell adhesion GO:0016337 131 0.017
chondrocyte differentiation GO:0002062 72 0.017
lung development GO:0030324 164 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.016
small molecule biosynthetic process GO:0044283 132 0.016
response to inorganic substance GO:0010035 96 0.016
response to transforming growth factor beta GO:0071559 88 0.016
respiratory system development GO:0060541 190 0.016
gastrulation GO:0007369 116 0.016
compound eye development GO:0048749 1 0.016
regulation of protein kinase activity GO:0045859 232 0.016
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
regulation of kinase activity GO:0043549 249 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
regulation of inflammatory response GO:0050727 147 0.016
organophosphate catabolic process GO:0046434 232 0.015
regulation of action potential GO:0098900 4 0.015
regionalization GO:0003002 337 0.015
molting cycle GO:0042303 90 0.015
multicellular organismal signaling GO:0035637 91 0.015
regulation of cellular amino acid metabolic process GO:0006521 5 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
camera type eye development GO:0043010 266 0.015
ras protein signal transduction GO:0007265 77 0.015
phagocytosis GO:0006909 66 0.015
endochondral bone morphogenesis GO:0060350 50 0.015
biomineral tissue development GO:0031214 64 0.015
ventricular cardiac muscle tissue development GO:0003229 38 0.015
regulation of neuron projection development GO:0010975 169 0.015
cellular response to external stimulus GO:0071496 88 0.015
branching morphogenesis of an epithelial tube GO:0048754 159 0.015
positive regulation of defense response GO:0031349 124 0.015
cellular response to lipid GO:0071396 145 0.015
digestive tract morphogenesis GO:0048546 147 0.014
positive regulation of cell substrate adhesion GO:0010811 47 0.014
establishment or maintenance of cell polarity GO:0007163 86 0.014
transmembrane transport GO:0055085 412 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.014
regulation of ossification GO:0030278 112 0.014
urogenital system development GO:0001655 261 0.014
regulation of anatomical structure size GO:0090066 178 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.014
bmp signaling pathway GO:0030509 93 0.014
cellular response to x ray GO:0071481 2 0.014
regulation of blood pressure GO:0008217 93 0.014
regulation of actin filament based process GO:0032970 99 0.014
regulation of cellular component size GO:0032535 121 0.014
fibrinolysis GO:0042730 3 0.014
cellular response to acid chemical GO:0071229 68 0.013
developmental cell growth GO:0048588 84 0.013
regulation of cell substrate adhesion GO:0010810 73 0.013
negative regulation of cell substrate adhesion GO:0010812 16 0.013
actin mediated cell contraction GO:0070252 15 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
bone mineralization GO:0030282 54 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
positive regulation of protein modification process GO:0031401 299 0.013
anatomical structure maturation GO:0071695 49 0.013
artery development GO:0060840 53 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
dna metabolic process GO:0006259 303 0.013
positive regulation of cytokine production GO:0001819 174 0.013
regulation of cellular amine metabolic process GO:0033238 20 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
leukocyte apoptotic process GO:0071887 71 0.013
regulation of neuron differentiation GO:0045664 281 0.013
fat cell differentiation GO:0045444 160 0.013
cell growth involved in cardiac muscle cell development GO:0061049 3 0.013
regulation of angiogenesis GO:0045765 81 0.013
negative regulation of cell proliferation involved in contact inhibition GO:0060244 3 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
anatomical structure homeostasis GO:0060249 145 0.013
spermatogenesis GO:0007283 284 0.013
ear morphogenesis GO:0042471 118 0.013
positive regulation of proteolysis GO:0045862 85 0.012
calcium ion homeostasis GO:0055074 127 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
carbohydrate homeostasis GO:0033500 128 0.012
regulation of peptidase activity GO:0052547 96 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
negative regulation of growth GO:0045926 99 0.012
membrane raft assembly GO:0001765 3 0.012
neural precursor cell proliferation GO:0061351 121 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
synaptic transmission GO:0007268 329 0.012
response to steroid hormone GO:0048545 56 0.012
sensory perception GO:0007600 245 0.012
peptidyl proline hydroxylation GO:0019511 3 0.012
positive regulation of cell adhesion GO:0045785 80 0.012
negative regulation of synapse assembly GO:0051964 3 0.012
fatty acid transport GO:0015908 28 0.012
negative regulation of protein modification process GO:0031400 163 0.012
cellular response to oxidative stress GO:0034599 76 0.012
face morphogenesis GO:0060325 29 0.012
calcium ion transport GO:0006816 159 0.012
negative regulation of proteolysis GO:0045861 74 0.012
regulation of cysteine type endopeptidase activity GO:2000116 65 0.012
neuron death GO:0070997 154 0.012
development of primary female sexual characteristics GO:0046545 73 0.012
response to amino acid GO:0043200 37 0.012
muscle system process GO:0003012 141 0.012
regulation of proteolysis GO:0030162 164 0.011
transmission of nerve impulse GO:0019226 76 0.011
cell chemotaxis GO:0060326 81 0.011
embryonic limb morphogenesis GO:0030326 126 0.011
stem cell development GO:0048864 219 0.011
covalent chromatin modification GO:0016569 163 0.011
cellular ion homeostasis GO:0006873 165 0.011
negative regulation of peptidase activity GO:0010466 46 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
circadian regulation of gene expression GO:0032922 48 0.011
lateral line system development GO:0048925 1 0.011
response to oxygen levels GO:0070482 62 0.011
sensory system development GO:0048880 3 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
cardiac muscle cell differentiation GO:0055007 69 0.011
response to purine containing compound GO:0014074 28 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
retinoid metabolic process GO:0001523 24 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
regulation of systemic arterial blood pressure GO:0003073 61 0.011
sensory perception of sound GO:0007605 97 0.011
embryonic placenta development GO:0001892 98 0.011
notochord development GO:0030903 20 0.011
negative regulation of protein maturation GO:1903318 79 0.011
alcohol metabolic process GO:0006066 116 0.011
negative regulation of odontogenesis GO:0042483 3 0.011
negative regulation of neuron death GO:1901215 98 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
regulation of biomineral tissue development GO:0070167 33 0.011
granulocyte migration GO:0097530 43 0.011
chromatin organization GO:0006325 206 0.011
epithelial tube formation GO:0072175 130 0.011
vitamin d biosynthetic process GO:0042368 3 0.011
organic anion transport GO:0015711 137 0.011
cardiac cell development GO:0055006 41 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.010
gonad development GO:0008406 141 0.010
palate development GO:0060021 76 0.010
negative regulation of phosphorylation GO:0042326 166 0.010
response to radiation GO:0009314 165 0.010
mitotic cell cycle process GO:1903047 159 0.010
cerebellum development GO:0021549 77 0.010
protein oligomerization GO:0051259 67 0.010
retinal blood vessel morphogenesis GO:0061304 3 0.010
regulation of protein maturation GO:1903317 96 0.010
acetylcholine secretion neurotransmission GO:0014055 2 0.010
negative regulation of endopeptidase activity GO:0010951 44 0.010
cellular metal ion homeostasis GO:0006875 151 0.010

Tmem45a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.066
musculoskeletal system disease DOID:17 0 0.066
nervous system disease DOID:863 0 0.025
connective tissue disease DOID:65 0 0.025
neuromuscular disease DOID:440 0 0.015
charcot marie tooth disease DOID:10595 0 0.015
neuropathy DOID:870 0 0.015
myopathy DOID:423 0 0.014
congenital muscular dystrophy DOID:0050557 0 0.014
muscular disease DOID:0080000 0 0.014
muscular dystrophy DOID:9884 0 0.014
muscle tissue disease DOID:66 0 0.014
collagen disease DOID:854 0 0.013
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
bone development disease DOID:0080006 0 0.012
bone disease DOID:0080001 0 0.012