|
|
cytokine production
|
GO:0001816 |
319 |
0.824
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.790
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.736
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.728
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.712
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.688
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.666
|
Fly |
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.628
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.621
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.571
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.534
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.505
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.440
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.437
|
|
|
|
tor signaling
|
GO:0031929 |
21 |
0.432
|
Fly |
|
|
immune effector process
|
GO:0002252 |
321 |
0.432
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.426
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.424
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.389
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.387
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.379
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.359
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.351
|
Mouse Fly |
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.346
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.345
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.334
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.332
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.331
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.320
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.319
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.319
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.307
|
Mouse Fly |
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.305
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.299
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.299
|
Mouse Fly |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.297
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.296
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.294
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.293
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.275
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.270
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.269
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.263
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.258
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.248
|
|
|
|
response to ethanol
|
GO:0045471 |
18 |
0.247
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.247
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.243
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.239
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.237
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.234
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.233
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.233
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.232
|
Fly |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.231
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.229
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.229
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.227
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.226
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.221
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.220
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.219
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.210
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.205
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.204
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.200
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.197
|
Mouse |
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
13 |
0.196
|
Fly |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.194
|
|
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.190
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.188
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.182
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.182
|
Fly |
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.180
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.179
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.176
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.174
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.173
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.171
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.169
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.168
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.167
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.165
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.164
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.158
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.158
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.156
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.153
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.152
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.151
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.150
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.146
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.144
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.140
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.139
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.138
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.137
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.136
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.134
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.132
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.128
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.127
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.126
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.126
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.125
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.125
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.123
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.123
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.120
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.119
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.119
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.116
|
Mouse |
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.115
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.112
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.108
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.108
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.107
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.107
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.104
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.102
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.101
|
Yeast Mouse Fly |
|
|
interleukin 8 secretion
|
GO:0072606 |
3 |
0.100
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.099
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.097
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.095
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.094
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.093
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.093
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.093
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.092
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.090
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.090
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.089
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.089
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.089
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.088
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.087
|
Mouse |
|
|
triglyceride homeostasis
|
GO:0070328 |
15 |
0.086
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.086
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.086
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.083
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.083
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.081
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.080
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.080
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.079
|
Yeast Worm |
|
|
regulation of tor signaling
|
GO:0032006 |
17 |
0.079
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.079
|
Mouse |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.079
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.078
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.078
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.077
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.077
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.076
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.076
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.076
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.076
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.074
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.074
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
2 |
0.074
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.073
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.072
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.072
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.071
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.071
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.071
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.071
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.070
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.069
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.068
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.068
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.067
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.067
|
Mouse |
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.067
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.067
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.066
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.065
|
Mouse |
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.065
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.064
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.064
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.063
|
Worm |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.063
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.063
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.063
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.062
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.062
|
Mouse |
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.061
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.061
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.060
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.060
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.060
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.060
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.060
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.059
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.059
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.059
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.058
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.058
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.058
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.057
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.057
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.057
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.057
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.057
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.057
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.056
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.056
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.056
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.055
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.055
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.055
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.054
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.054
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.054
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.054
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.054
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.053
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.053
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.053
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.052
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.052
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.052
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.052
|
Fly |
|
|
b cell activation
|
GO:0042113 |
161 |
0.052
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.052
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.051
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.051
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.051
|
|
|
|
acylglycerol homeostasis
|
GO:0055090 |
16 |
0.050
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.050
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.049
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.049
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.049
|
Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.049
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.048
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.048
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.048
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.048
|
|
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
6 |
0.048
|
Fly |
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.048
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.047
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.047
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.046
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.046
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.046
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.046
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.045
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.045
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.045
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.045
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.045
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.045
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.045
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.045
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.045
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.044
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.044
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.044
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.044
|
Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.044
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.044
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.044
|
|
|
|
regulation of morphogenesis of a branching structure
|
GO:0060688 |
53 |
0.043
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.043
|
|
|
|
fatty acid transport
|
GO:0015908 |
28 |
0.043
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.043
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.043
|
|
|
|
kit signaling pathway
|
GO:0038109 |
3 |
0.043
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.042
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.042
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.041
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.041
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.041
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.041
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
16 |
0.041
|
Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.041
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.040
|
|
|
|
neutrophil mediated killing of gram positive bacterium
|
GO:0070946 |
2 |
0.040
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.040
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.040
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.040
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.040
|
|
|
|
pyridine containing compound catabolic process
|
GO:0072526 |
4 |
0.040
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.039
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.039
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.038
|
Fly |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.038
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.038
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.038
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.038
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.038
|
Fly |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.038
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.037
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.037
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.037
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.037
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.037
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.037
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.037
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.037
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.037
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.037
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.036
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.036
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.036
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.036
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.036
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.036
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.035
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.035
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.035
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.034
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.034
|
|
|
|
cell cell adhesion via plasma membrane adhesion molecules
|
GO:0098742 |
40 |
0.034
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.034
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.034
|
|
|
|
regulation of neural retina development
|
GO:0061074 |
3 |
0.034
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
44 |
0.034
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.034
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.034
|
Mouse |
|
|
hormone secretion
|
GO:0046879 |
128 |
0.034
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.033
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.033
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.033
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.033
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.033
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.033
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.032
|
|
|
|
positive regulation of interleukin 8 secretion
|
GO:2000484 |
1 |
0.032
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.032
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.032
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.032
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.032
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.032
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.032
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.031
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.031
|
Worm |
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.031
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.031
|
Fly |
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.031
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.031
|
Mouse |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.031
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.031
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.031
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.031
|
|
|
|
cellular response to interleukin 15
|
GO:0071350 |
2 |
0.031
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.030
|
|
|
|
cofactor transport
|
GO:0051181 |
4 |
0.030
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.030
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.030
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.030
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.030
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.030
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.030
|
|
|
|
icosanoid secretion
|
GO:0032309 |
12 |
0.030
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.030
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.030
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.030
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.030
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.029
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.029
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.029
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.029
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
2 |
0.029
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.029
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.028
|
|
|
|
t cell mediated cytotoxicity
|
GO:0001913 |
26 |
0.028
|
|
|
|
positive regulation of mast cell activation
|
GO:0033005 |
12 |
0.028
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.028
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.028
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.028
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.028
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.028
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.028
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.028
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.028
|
Fly |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.028
|
|
|
|
regulation of tissue remodeling
|
GO:0034103 |
38 |
0.027
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.027
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.027
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.027
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.027
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.027
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.027
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.027
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.027
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.027
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.026
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.026
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.026
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.026
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.026
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.026
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.026
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.026
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.026
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.026
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.026
|
Fly |
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.026
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.025
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.025
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.025
|
|
|
|
cell cell adhesion
|
GO:0098609 |
41 |
0.025
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.025
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.025
|
Mouse |
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.025
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.025
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.025
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.025
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.025
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.025
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.024
|
|
|
|
macrophage chemotaxis
|
GO:0048246 |
14 |
0.024
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.024
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.024
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.024
|
|
|
|
anatomical structure maturation
|
GO:0071695 |
49 |
0.024
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.024
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.024
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.024
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.024
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.024
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.024
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.024
|
|
|
|
response to stem cell factor
|
GO:0036215 |
3 |
0.024
|
|
|
|
metanephric glomerulus vasculature morphogenesis
|
GO:0072276 |
3 |
0.023
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.023
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.023
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.023
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.023
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.023
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.023
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.023
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.023
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.023
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.023
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.023
|
|
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
21 |
0.023
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.023
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.023
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.023
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.022
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.022
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.022
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.022
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
41 |
0.022
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.022
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.022
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.022
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.022
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.022
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.022
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
8 |
0.022
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.022
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.022
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.022
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.022
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.021
|
Worm |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.021
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.021
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.021
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.021
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.021
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.021
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.021
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.021
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.021
|
Fly |
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.021
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.021
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.021
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.021
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.021
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.021
|
|
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.020
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.020
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.020
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.020
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.020
|
|
|
|
cellular response to stem cell factor stimulus
|
GO:0036216 |
3 |
0.020
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.020
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.020
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.020
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.020
|
|
|
|
regulation of prostaglandin secretion
|
GO:0032306 |
5 |
0.020
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.020
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.020
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.020
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.020
|
Fly |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.020
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.020
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.019
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.019
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.019
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.019
|
|
