Mus musculus

7 known processes

Pmvk

phosphomevalonate kinase

(Aliases: PMKASE,2900002L22Rik,1110011E12Rik,AV001327,PMKA,PMK)

Pmvk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sterol metabolic process GO:0016125 58 0.244
lipid biosynthetic process GO:0008610 179 0.189
cellular lipid metabolic process GO:0044255 323 0.162
alcohol metabolic process GO:0006066 116 0.128
small molecule biosynthetic process GO:0044283 132 0.116
cellular amino acid metabolic process GO:0006520 103 0.087
cellular alcohol biosynthetic process GO:0044108 3 0.084
organic hydroxy compound metabolic process GO:1901615 203 0.080
alcohol biosynthetic process GO:0046165 43 0.079
oxidation reduction process GO:0055114 342 0.079
steroid metabolic process GO:0008202 119 0.076
cellular ketone metabolic process GO:0042180 84 0.073
cellular alcohol metabolic process GO:0044107 3 0.072
regulation of cellular ketone metabolic process GO:0010565 66 0.058
sterol biosynthetic process GO:0016126 17 0.049
amine metabolic process GO:0009308 45 0.047
nucleoside phosphate metabolic process GO:0006753 338 0.046
nucleobase containing small molecule metabolic process GO:0055086 352 0.046
monocarboxylic acid metabolic process GO:0032787 191 0.040
regulation of cellular amine metabolic process GO:0033238 20 0.039
cofactor metabolic process GO:0051186 80 0.038
purine nucleotide metabolic process GO:0006163 302 0.037
nucleoside metabolic process GO:0009116 246 0.037
cellular amine metabolic process GO:0044106 44 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
organic hydroxy compound biosynthetic process GO:1901617 77 0.035
purine nucleoside metabolic process GO:0042278 241 0.034
purine ribonucleotide metabolic process GO:0009150 290 0.034
ribonucleoside triphosphate metabolic process GO:0009199 220 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
cholesterol metabolic process GO:0008203 56 0.033
glycosyl compound metabolic process GO:1901657 246 0.032
ribose phosphate metabolic process GO:0019693 291 0.032
negative regulation of molecular function GO:0044092 258 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
thioester biosynthetic process GO:0035384 7 0.030
purine containing compound metabolic process GO:0072521 311 0.030
regulation of organelle organization GO:0033043 289 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.029
nucleoside triphosphate metabolic process GO:0009141 230 0.029
nucleotide metabolic process GO:0009117 332 0.028
purine ribonucleoside metabolic process GO:0046128 241 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
aromatic compound catabolic process GO:0019439 286 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
carbohydrate metabolic process GO:0005975 230 0.027
ribonucleoside metabolic process GO:0009119 245 0.027
cation transport GO:0006812 399 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.027
coenzyme metabolic process GO:0006732 52 0.026
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
nadph regeneration GO:0006740 2 0.026
heterocycle catabolic process GO:0046700 280 0.026
organic cyclic compound catabolic process GO:1901361 295 0.025
regulation of defense response GO:0031347 233 0.025
regulation of response to wounding GO:1903034 189 0.025
response to organonitrogen compound GO:0010243 246 0.025
positive regulation of protein modification process GO:0031401 299 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
regulation of hormone levels GO:0010817 211 0.024
response to acid chemical GO:0001101 111 0.024
coenzyme biosynthetic process GO:0009108 23 0.024
inflammatory response GO:0006954 244 0.024
nitrogen compound transport GO:0071705 271 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.023
steroid biosynthetic process GO:0006694 47 0.023
regulation of transferase activity GO:0051338 263 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
regulation of kinase activity GO:0043549 249 0.023
cellular response to lipid GO:0071396 145 0.023
isoprenoid biosynthetic process GO:0008299 9 0.023
nucleotide catabolic process GO:0009166 217 0.022
mitochondrion organization GO:0007005 134 0.022
ketone body metabolic process GO:1902224 3 0.022
gland development GO:0048732 330 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
generation of precursor metabolites and energy GO:0006091 103 0.022
organophosphate catabolic process GO:0046434 232 0.022
hexose catabolic process GO:0019320 3 0.021
cytoplasmic transport GO:0016482 234 0.021
cellular homeostasis GO:0019725 240 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
regulation of protein kinase activity GO:0045859 232 0.021
response to extracellular stimulus GO:0009991 127 0.020
cholesterol biosynthetic process GO:0006695 15 0.020
response to organic cyclic compound GO:0014070 198 0.020
response to oxidative stress GO:0006979 123 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.019
mapk cascade GO:0000165 281 0.019
sulfur compound metabolic process GO:0006790 100 0.019
membrane organization GO:0061024 245 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
small molecule catabolic process GO:0044282 71 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
ras protein signal transduction GO:0007265 77 0.019
spermatogenesis GO:0007283 284 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
cellular chemical homeostasis GO:0055082 215 0.019
glycerolipid metabolic process GO:0046486 122 0.019
regulation of secretion GO:0051046 274 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
intracellular protein transport GO:0006886 204 0.019
apoptotic signaling pathway GO:0097190 306 0.018
response to nutrient levels GO:0031667 109 0.018
male gamete generation GO:0048232 285 0.018
transmembrane transport GO:0055085 412 0.018
regulation of hydrolase activity GO:0051336 246 0.018
monocarboxylic acid biosynthetic process GO:0072330 61 0.018
nucleoside catabolic process GO:0009164 206 0.018
regulation of inflammatory response GO:0050727 147 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
ion transmembrane transport GO:0034220 361 0.018
protein catabolic process GO:0030163 221 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
liver development GO:0001889 66 0.018
monosaccharide metabolic process GO:0005996 106 0.018
homeostasis of number of cells GO:0048872 210 0.018
negative regulation of protein modification process GO:0031400 163 0.017
cation transmembrane transport GO:0098655 266 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
regulation of secretion by cell GO:1903530 249 0.017
maintenance of location GO:0051235 89 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
rho protein signal transduction GO:0007266 32 0.017
cell type specific apoptotic process GO:0097285 268 0.017
acyl coa metabolic process GO:0006637 19 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
striated muscle tissue development GO:0014706 293 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
macromolecule catabolic process GO:0009057 281 0.017
purine containing compound catabolic process GO:0072523 213 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
response to radiation GO:0009314 165 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
organic acid biosynthetic process GO:0016053 86 0.016
positive regulation of cell development GO:0010720 237 0.016
regulation of protein localization GO:0032880 231 0.016
compound eye development GO:0048749 1 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
myeloid cell differentiation GO:0030099 233 0.015
positive regulation of transferase activity GO:0051347 167 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
fat cell differentiation GO:0045444 160 0.015
actin cytoskeleton organization GO:0030036 220 0.015
dna metabolic process GO:0006259 303 0.015
cellular response to acid chemical GO:0071229 68 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
regulation of neuron differentiation GO:0045664 281 0.015
regulation of ion transport GO:0043269 215 0.015
microtubule based process GO:0007017 236 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
blood circulation GO:0008015 195 0.015
muscle tissue development GO:0060537 308 0.015
synaptic transmission GO:0007268 329 0.015
multicellular organism growth GO:0035264 161 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
protein maturation GO:0051604 176 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
regulation of mapk cascade GO:0043408 248 0.014
regulation of cell projection organization GO:0031344 206 0.014
lipid localization GO:0010876 126 0.014
cellular response to external stimulus GO:0071496 88 0.014
regulation of anatomical structure size GO:0090066 178 0.014
leukocyte differentiation GO:0002521 342 0.014
peptidyl amino acid modification GO:0018193 336 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
muscle cell differentiation GO:0042692 261 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
regulation of membrane potential GO:0042391 192 0.014
neuron death GO:0070997 154 0.014
response to inorganic substance GO:0010035 96 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
cofactor biosynthetic process GO:0051188 41 0.014
nuclear transport GO:0051169 139 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.013
carbohydrate homeostasis GO:0033500 128 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
glucose homeostasis GO:0042593 128 0.013
fatty acid metabolic process GO:0006631 121 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
nucleoside phosphate biosynthetic process GO:1901293 79 0.013
hexose metabolic process GO:0019318 98 0.013
positive regulation of cell death GO:0010942 224 0.013
response to lipopolysaccharide GO:0032496 128 0.013
immune effector process GO:0002252 321 0.013
positive regulation of nervous system development GO:0051962 221 0.013
regulation of cell cycle GO:0051726 281 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
isoprenoid metabolic process GO:0006720 29 0.013
cellular response to nutrient levels GO:0031669 64 0.013
adult behavior GO:0030534 135 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
regulation of cell activation GO:0050865 289 0.013
forebrain development GO:0030900 302 0.013
germ cell development GO:0007281 185 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
cytokine production GO:0001816 319 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
regulation of cellular response to stress GO:0080135 159 0.013
regulation of cell motility GO:2000145 236 0.012
cellular protein complex assembly GO:0043623 116 0.012
response to peptide GO:1901652 136 0.012
positive regulation of kinase activity GO:0033674 155 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
organelle localization GO:0051640 179 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
fatty acid biosynthetic process GO:0006633 41 0.012
glucose metabolic process GO:0006006 92 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
organic anion transport GO:0015711 137 0.012
sensory perception GO:0007600 245 0.012
organelle assembly GO:0070925 177 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
regulation of intracellular transport GO:0032386 159 0.012
regulation of homeostatic process GO:0032844 182 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
gtp catabolic process GO:0006184 143 0.012
striated muscle myosin thick filament assembly GO:0071688 1 0.012
positive regulation of secretion GO:0051047 130 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
cell adhesion GO:0007155 329 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
response to starvation GO:0042594 65 0.012
rhythmic process GO:0048511 174 0.012
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.011
protein oligomerization GO:0051259 67 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
skin development GO:0043588 220 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
myosin filament assembly GO:0031034 2 0.011
ketone catabolic process GO:0042182 3 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
protein processing GO:0016485 163 0.011
organelle fission GO:0048285 170 0.011
regulation of cytokine production GO:0001817 266 0.011
negative regulation of transferase activity GO:0051348 85 0.011
metal ion homeostasis GO:0055065 189 0.011
response to testosterone GO:0033574 3 0.011
endocytosis GO:0006897 168 0.011
regulation of immunological synapse formation GO:2000520 2 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
multicellular organismal signaling GO:0035637 91 0.011
positive regulation of organelle organization GO:0010638 128 0.011
glucose catabolic process GO:0006007 3 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
divalent inorganic cation transport GO:0072511 178 0.011
response to peptide hormone GO:0043434 127 0.011
t cell activation GO:0042110 289 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
myosin filament organization GO:0031033 3 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
respiratory tube development GO:0030323 167 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
regulation of neuron death GO:1901214 134 0.010
protein localization to nucleus GO:0034504 121 0.010
negative regulation of defense response GO:0031348 77 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
camera type eye development GO:0043010 266 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
negative regulation of phosphorylation GO:0042326 166 0.010
regulation of proteolysis GO:0030162 164 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
carbohydrate catabolic process GO:0016052 32 0.010
response to light stimulus GO:0009416 135 0.010
regulation of map kinase activity GO:0043405 120 0.010
organic acid transport GO:0015849 101 0.010
skeletal muscle organ development GO:0060538 163 0.010
regulation of system process GO:0044057 200 0.010
cellular response to oxidative stress GO:0034599 76 0.010
thioester metabolic process GO:0035383 19 0.010
neuronal action potential GO:0019228 54 0.010
dephosphorylation GO:0016311 129 0.010
neural tube development GO:0021915 160 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
circulatory system process GO:0003013 197 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
peptidyl tyrosine phosphorylation GO:0018108 143 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010

Pmvk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.031
inherited metabolic disorder DOID:655 0 0.028
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
immune system disease DOID:2914 0 0.014
disease of cellular proliferation DOID:14566 0 0.011