Mus musculus

128 known processes

Flt3

FMS-like tyrosine kinase 3

(Aliases: Flt-3,Flk2,B230315G04,Flk-2,MGC124378,wmfl,CD135,Ly72,MGC124377)

Flt3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
t cell activation GO:0042110 289 0.714
leukocyte differentiation GO:0002521 342 0.712
immune response activating signal transduction GO:0002757 116 0.621
cytokine production GO:0001816 319 0.609
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.594
activation of immune response GO:0002253 138 0.583
cell recognition GO:0008037 83 0.552
myeloid cell differentiation GO:0030099 233 0.540
Mouse
positive regulation of cytokine production GO:0001819 174 0.501
response to lipopolysaccharide GO:0032496 128 0.498
hematopoietic stem cell migration GO:0035701 1 0.479
regulation of cytokine production GO:0001817 266 0.476
lymphocyte proliferation GO:0046651 164 0.449
lymphocyte differentiation GO:0030098 242 0.443
regulation of t cell activation GO:0050863 170 0.438
transmembrane transport GO:0055085 412 0.425
Mouse
cytokine biosynthetic process GO:0042089 68 0.402
membrane organization GO:0061024 245 0.397
regulation of ion homeostasis GO:2000021 64 0.397
regulation of monocyte chemotaxis GO:0090025 3 0.389
adaptive immune response GO:0002250 155 0.384
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.367
regulation of adaptive immune response GO:0002819 90 0.366
positive regulation of monocyte chemotaxis GO:0090026 2 0.353
regulation of cytokine biosynthetic process GO:0042035 59 0.350
positive regulation of t cell activation GO:0050870 101 0.343
positive regulation of tumor necrosis factor production GO:0032760 30 0.340
cell cell recognition GO:0009988 44 0.326
mature dendritic cell differentiation GO:0097029 3 0.322
cell chemotaxis GO:0060326 81 0.322
Mouse
regulation of establishment of protein localization GO:0070201 181 0.321
defense response to other organism GO:0098542 197 0.320
sequestering of calcium ion GO:0051208 18 0.316
action potential GO:0001508 78 0.304
cellular response to lipid GO:0071396 145 0.303
Rat
t cell differentiation GO:0030217 174 0.299
cytokine mediated signaling pathway GO:0019221 115 0.297
regulation of leukocyte apoptotic process GO:2000106 56 0.272
leukocyte activation involved in immune response GO:0002366 126 0.265
alpha beta t cell activation GO:0046631 91 0.243
divalent inorganic cation transport GO:0072511 178 0.240
Mouse
single organismal cell cell adhesion GO:0016337 131 0.236
Mouse
activation of innate immune response GO:0002218 56 0.236
regulation of lymphocyte activation GO:0051249 240 0.235
negative regulation of immune system process GO:0002683 209 0.233
regulation of response to wounding GO:1903034 189 0.232
immune response regulating signaling pathway GO:0002764 125 0.230
regulation of membrane potential GO:0042391 192 0.218
natural killer cell activation GO:0030101 44 0.213
cytosolic calcium ion transport GO:0060401 48 0.211
lymphocyte mediated immunity GO:0002449 139 0.210
germ cell development GO:0007281 185 0.207
Mouse Fly
immune effector process GO:0002252 321 0.206
Mouse
regulation of intracellular transport GO:0032386 159 0.200
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.198
regulation of tumor necrosis factor production GO:0032680 49 0.198
defense response to bacterium GO:0042742 119 0.197
multicellular organismal signaling GO:0035637 91 0.197
tumor necrosis factor production GO:0032640 50 0.197
regulation of lymphocyte proliferation GO:0050670 117 0.197
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.195
myeloid leukocyte differentiation GO:0002573 119 0.194
Mouse
leukocyte chemotaxis GO:0030595 69 0.191
t cell proliferation GO:0042098 120 0.190
mapk cascade GO:0000165 281 0.187
Mouse Fly
inflammatory response GO:0006954 244 0.183
Mouse
negative regulation of homeostatic process GO:0032845 71 0.180
regulation of vesicle mediated transport GO:0060627 139 0.179
positive regulation of protein secretion GO:0050714 52 0.177
blood vessel morphogenesis GO:0048514 285 0.175
Mouse
regulation of protein localization GO:0032880 231 0.175
protein secretion GO:0009306 111 0.164
cell activation involved in immune response GO:0002263 126 0.163
cytokine secretion GO:0050663 72 0.163
cell killing GO:0001906 67 0.162
regulation of type 2 immune response GO:0002828 18 0.161
glycoprotein biosynthetic process GO:0009101 89 0.160
cytokine metabolic process GO:0042107 71 0.160
muscle cell development GO:0055001 133 0.157
Mouse
humoral immune response GO:0006959 57 0.156
Fly
neuronal action potential GO:0019228 54 0.155
cellular amino acid metabolic process GO:0006520 103 0.152
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.151
metal ion homeostasis GO:0055065 189 0.151
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.149
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.149
actin cytoskeleton organization GO:0030036 220 0.149
Mouse Fly
regulation of defense response GO:0031347 233 0.147
phagocytosis GO:0006909 66 0.146
sequestering of metal ion GO:0051238 19 0.146
transmission of nerve impulse GO:0019226 76 0.145
epithelial tube morphogenesis GO:0060562 303 0.145
Mouse Fly
positive regulation of neuron differentiation GO:0045666 141 0.144
carbohydrate derivative biosynthetic process GO:1901137 183 0.143
positive regulation of defense response GO:0031349 124 0.142
regulation of leukocyte mediated immunity GO:0002703 104 0.140
positive regulation of cell development GO:0010720 237 0.139
cation transport GO:0006812 399 0.139
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.139
Mouse
cell type specific apoptotic process GO:0097285 268 0.139
leukocyte apoptotic process GO:0071887 71 0.136
regulation of endocytosis GO:0030100 69 0.134
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.134
g protein coupled receptor signaling pathway GO:0007186 243 0.134
regulation of interferon gamma production GO:0032649 57 0.133
myeloid leukocyte migration GO:0097529 57 0.133
cellular response to lipopolysaccharide GO:0071222 77 0.132
monocyte extravasation GO:0035696 2 0.132
cellular calcium ion homeostasis GO:0006874 119 0.132
regulation of protein transport GO:0051223 163 0.132
axon ensheathment GO:0008366 76 0.131
negative regulation of multi organism process GO:0043901 68 0.131
angiogenesis GO:0001525 201 0.128
Mouse
negative regulation of cell activation GO:0050866 111 0.128
chemokine mediated signaling pathway GO:0070098 17 0.126
axonogenesis GO:0007409 274 0.126
regulation of hematopoietic stem cell migration GO:2000471 1 0.124
positive regulation of phagocytosis GO:0050766 26 0.124
gliogenesis GO:0042063 141 0.121
regulation of cytokine secretion GO:0050707 61 0.120
regulation of secretion by cell GO:1903530 249 0.120
cellular response to cytokine stimulus GO:0071345 189 0.119
cytoplasmic transport GO:0016482 234 0.119
positive regulation of protein modification process GO:0031401 299 0.119
positive regulation of interferon gamma production GO:0032729 39 0.118
positive regulation of gliogenesis GO:0014015 27 0.118
innate immune response GO:0045087 157 0.118
Fly
ion transmembrane transport GO:0034220 361 0.118
Mouse
regulation of anatomical structure size GO:0090066 178 0.118
regulation of homeostatic process GO:0032844 182 0.118
anatomical structure homeostasis GO:0060249 145 0.118
Mouse
interleukin 12 secretion GO:0072610 3 0.117
divalent metal ion transport GO:0070838 172 0.116
Mouse
synaptic transmission GO:0007268 329 0.114
leukocyte migration GO:0050900 124 0.114
cellular response to biotic stimulus GO:0071216 92 0.111
regulation of cellular amine metabolic process GO:0033238 20 0.111
regulation of kinase activity GO:0043549 249 0.111
Mouse
helper t cell chemotaxis GO:0035704 1 0.110
positive regulation of cell projection organization GO:0031346 95 0.109
endocytosis GO:0006897 168 0.109
small gtpase mediated signal transduction GO:0007264 97 0.109
b cell activation GO:0042113 161 0.108
chemotaxis GO:0006935 247 0.108
Mouse
positive regulation of immune effector process GO:0002699 107 0.107
myeloid leukocyte mediated immunity GO:0002444 42 0.106
granulocyte migration GO:0097530 43 0.102
positive regulation of nervous system development GO:0051962 221 0.101
regulation of cell projection organization GO:0031344 206 0.101
leukocyte proliferation GO:0070661 172 0.101
leukocyte mediated immunity GO:0002443 174 0.100
Mouse
amine metabolic process GO:0009308 45 0.099
reactive nitrogen species metabolic process GO:2001057 0 0.099
regulation of cellular response to stress GO:0080135 159 0.099
regulation of ion transport GO:0043269 215 0.098
Mouse
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.098
neuron projection guidance GO:0097485 141 0.097
regulation of neuron projection development GO:0010975 169 0.096
leukocyte mediated cytotoxicity GO:0001909 62 0.096
myeloid leukocyte activation GO:0002274 83 0.096
single organism cell adhesion GO:0098602 156 0.096
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.094
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.094
defense response to virus GO:0051607 68 0.092
granulocyte chemotaxis GO:0071621 39 0.092
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.090
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.090
negative regulation of defense response GO:0031348 77 0.090
detection of other organism GO:0098543 8 0.090
regulation of protein secretion GO:0050708 82 0.090
positive regulation of angiogenesis GO:0045766 46 0.089
Mouse
homeostasis of number of cells GO:0048872 210 0.088
activation of mapk activity involved in innate immune response GO:0035419 2 0.088
innate immune response activating signal transduction GO:0002758 50 0.088
regulation of innate immune response GO:0045088 91 0.088
negative regulation of phagocytosis GO:0050765 4 0.087
eosinophil activation GO:0043307 1 0.087
eosinophil degranulation GO:0043308 1 0.087
regulation of epithelial cell proliferation GO:0050678 141 0.087
Mouse
glial cell development GO:0021782 54 0.087
eosinophil mediated immunity GO:0002447 1 0.086
negative regulation of immune effector process GO:0002698 55 0.085
regulation of t cell proliferation GO:0042129 92 0.085
multicellular organismal homeostasis GO:0048871 164 0.084
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.084
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.084
eosinophil migration GO:0072677 3 0.084
cation homeostasis GO:0055080 212 0.084
Mouse
response to molecule of bacterial origin GO:0002237 143 0.083
membrane invagination GO:0010324 17 0.083
cognition GO:0050890 149 0.083
calcium ion transport into cytosol GO:0060402 48 0.081
regulation of transferase activity GO:0051338 263 0.080
Mouse
ensheathment of neurons GO:0007272 76 0.078
regulation of phagocytosis GO:0050764 33 0.078
positive regulation of lymphocyte activation GO:0051251 140 0.078
myelination GO:0042552 74 0.077
cytosolic calcium ion homeostasis GO:0051480 70 0.077
regulation of interleukin 12 production GO:0032655 30 0.077
negative regulation of macrophage apoptotic process GO:2000110 3 0.077
regulation of cellular component size GO:0032535 121 0.076
positive regulation of neuron projection development GO:0010976 79 0.076
regulation of apoptotic signaling pathway GO:2001233 197 0.076
learning or memory GO:0007611 148 0.075
calcium ion transport GO:0006816 159 0.075
Mouse
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.075
interferon gamma production GO:0032609 67 0.074
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.072
positive regulation of cell activation GO:0050867 158 0.072
regulation of cell activation GO:0050865 289 0.071
positive regulation of innate immune response GO:0045089 80 0.071
forebrain development GO:0030900 302 0.071
cellular lipid metabolic process GO:0044255 323 0.071
Mouse
maintenance of location GO:0051235 89 0.071
regulation of reactive oxygen species metabolic process GO:2000377 40 0.069
Mouse
single fertilization GO:0007338 82 0.069
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.069
regulation of leukocyte proliferation GO:0070663 121 0.069
regulation of neuron differentiation GO:0045664 281 0.069
exocytosis GO:0006887 121 0.068
muscle tissue development GO:0060537 308 0.068
Mouse
endomembrane system organization GO:0010256 147 0.068
pattern recognition receptor signaling pathway GO:0002221 47 0.068
interleukin 12 production GO:0032615 32 0.067
glial cell differentiation GO:0010001 131 0.067
circulatory system process GO:0003013 197 0.067
detection of yeast GO:0001879 2 0.067
regulation of cellular component biogenesis GO:0044087 181 0.067
t helper 17 cell chemotaxis GO:0035705 1 0.067
positive regulation of endocytosis GO:0045807 42 0.066
peptidyl tyrosine phosphorylation GO:0018108 143 0.066
regulation of t cell differentiation GO:0045580 83 0.066
response to organic cyclic compound GO:0014070 198 0.066
Rat
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.066
activation of membrane attack complex GO:0001905 4 0.065
cd4 positive alpha beta t cell activation GO:0035710 45 0.065
positive regulation of leukocyte proliferation GO:0070665 73 0.065
bone remodeling GO:0046849 53 0.064
positive regulation of adaptive immune response GO:0002821 61 0.063
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.063
glycoprotein metabolic process GO:0009100 116 0.063
positive regulation of leukocyte differentiation GO:1902107 86 0.063
epidermis development GO:0008544 187 0.062
response to growth factor GO:0070848 198 0.062
Mouse
alpha beta t cell differentiation GO:0046632 69 0.062
response to organonitrogen compound GO:0010243 246 0.062
Mouse Rat Fly
t helper 1 type immune response GO:0042088 25 0.061
regulation of metal ion transport GO:0010959 106 0.061
Mouse
cellular homeostasis GO:0019725 240 0.060
regulation of leukocyte differentiation GO:1902105 159 0.058
neutrophil migration GO:1990266 37 0.058
positive regulation of protein transport GO:0051222 93 0.058
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.058
actomyosin structure organization GO:0031032 56 0.058
Mouse
response to molecule of fungal origin GO:0002238 4 0.057
response to drug GO:0042493 75 0.057
positive regulation of interleukin 12 production GO:0032735 21 0.057
regulation of cell migration GO:0030334 219 0.056
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.056
cellular ketone metabolic process GO:0042180 84 0.056
dendritic cell differentiation GO:0097028 26 0.055
regulation of t helper 2 cell cytokine production GO:2000551 3 0.055
positive regulation of cytokine biosynthetic process GO:0042108 40 0.054
regulation of cytoplasmic transport GO:1903649 112 0.054
jnk cascade GO:0007254 72 0.054
blood circulation GO:0008015 195 0.054
neutrophil chemotaxis GO:0030593 36 0.053
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.053
nitrogen compound transport GO:0071705 271 0.053
positive regulation of t cell extravasation GO:2000409 2 0.053
regulation of inflammatory response GO:0050727 147 0.052
protein localization to nucleus GO:0034504 121 0.052
cellular ion homeostasis GO:0006873 165 0.052
establishment of protein localization to organelle GO:0072594 118 0.052
response to transforming growth factor beta GO:0071559 88 0.052
axon guidance GO:0007411 141 0.052
regulation of cellular amino acid metabolic process GO:0006521 5 0.051
natural killer cell mediated cytotoxicity GO:0042267 29 0.051
intracellular protein transport GO:0006886 204 0.051
t cell selection GO:0045058 34 0.051
divalent inorganic cation homeostasis GO:0072507 138 0.051
Mouse
protein localization to organelle GO:0033365 185 0.051
acute inflammatory response GO:0002526 41 0.051
telencephalon development GO:0021537 186 0.050
positive regulation of immunological synapse formation GO:2000522 1 0.050
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.050
positive regulation of t cell proliferation GO:0042102 52 0.050
inorganic anion transport GO:0015698 43 0.050
generation of precursor metabolites and energy GO:0006091 103 0.049
t cell differentiation in thymus GO:0033077 77 0.049
positive regulation of monocyte extravasation GO:2000439 1 0.049
microglial cell activation involved in immune response GO:0002282 1 0.049
purine nucleotide metabolic process GO:0006163 302 0.049
regulation of multi organism process GO:0043900 111 0.049
positive regulation of t cell differentiation GO:0045582 52 0.049
positive regulation of cytokine secretion GO:0050715 41 0.048
positive regulation of hydrolase activity GO:0051345 148 0.048
positive regulation of protein kinase activity GO:0045860 144 0.048
Mouse
protein targeting GO:0006605 143 0.047
negative regulation of eosinophil degranulation GO:0043310 1 0.047
positive regulation of response to wounding GO:1903036 66 0.047
regulation of t cell costimulation GO:2000523 2 0.047
positive regulation of homeostatic process GO:0032846 64 0.047
regulation of myeloid cell apoptotic process GO:0033032 19 0.046
phospholipid metabolic process GO:0006644 87 0.046
Mouse
neutrophil differentiation GO:0030223 3 0.046
b cell proliferation GO:0042100 53 0.046
negative regulation of cell proliferation GO:0008285 296 0.046
regulation of gliogenesis GO:0014013 50 0.046
regulation of cellular catabolic process GO:0031329 242 0.046
regulation of interleukin 1 production GO:0032652 26 0.046
regulation of lymphocyte differentiation GO:0045619 107 0.046
striated muscle cell development GO:0055002 125 0.045
Mouse
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.045
nuclear transport GO:0051169 139 0.045
regulation of calcium ion transport GO:0051924 69 0.045
Mouse
regulation of glial cell differentiation GO:0045685 41 0.045
regulation of mapk cascade GO:0043408 248 0.044
Mouse Fly
cytokine production involved in immune response GO:0002367 34 0.044
Mouse
positive regulation of lymphocyte migration GO:2000403 11 0.044
cell adhesion GO:0007155 329 0.044
Mouse
antigen processing and presentation GO:0019882 47 0.044
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.044
calcium ion homeostasis GO:0055074 127 0.044
Mouse
myeloid cell apoptotic process GO:0033028 22 0.044
regulation of dendritic cell chemotaxis GO:2000508 1 0.044
extrinsic apoptotic signaling pathway GO:0097191 126 0.044
regulation of cell motility GO:2000145 236 0.044
Mouse
tissue remodeling GO:0048771 102 0.043
Mouse
regulation of immunological synapse formation GO:2000520 2 0.043
release of sequestered calcium ion into cytosol GO:0051209 42 0.042
regulation of organelle organization GO:0033043 289 0.042
Mouse
peptidyl tyrosine modification GO:0018212 145 0.042
positive regulation of transferase activity GO:0051347 167 0.042
Mouse
eosinophil activation involved in immune response GO:0002278 1 0.041
regulation of eosinophil degranulation GO:0043309 1 0.041
cellular response to dna damage stimulus GO:0006974 207 0.041
Fly
nucleotide metabolic process GO:0009117 332 0.041
plasma membrane organization GO:0007009 90 0.041
microglial cell activation GO:0001774 3 0.041
macromolecule catabolic process GO:0009057 281 0.041
regulation of monocyte extravasation GO:2000437 2 0.041
stress activated protein kinase signaling cascade GO:0031098 81 0.040
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.040
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.040
carbohydrate metabolic process GO:0005975 230 0.040
fertilization GO:0009566 127 0.040
regulation of lymphocyte mediated immunity GO:0002706 84 0.040
skeletal muscle fiber development GO:0048741 58 0.039
positive regulation of cellular catabolic process GO:0031331 148 0.039
positive regulation of t cell costimulation GO:2000525 2 0.039
positive regulation of interferon alpha production GO:0032727 4 0.039
membrane depolarization GO:0051899 64 0.039
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.039
organelle assembly GO:0070925 177 0.039
Mouse
regulation of t cell extravasation GO:2000407 3 0.039
wnt signaling pathway GO:0016055 188 0.039
interspecies interaction between organisms GO:0044419 83 0.038
actin filament organization GO:0007015 113 0.038
Fly
regulation of alpha beta t cell activation GO:0046634 53 0.038
regulation of blood circulation GO:1903522 93 0.038
t cell migration GO:0072678 19 0.038
cell growth GO:0016049 130 0.038
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.037
Mouse
negative regulation of cellular component organization GO:0051129 194 0.037
negative regulation of cytokine production GO:0001818 84 0.037
positive regulation of inflammatory response GO:0050729 47 0.037
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.037
regulation of stress activated mapk cascade GO:0032872 69 0.037
purine containing compound metabolic process GO:0072521 311 0.036
positive regulation of kinase activity GO:0033674 155 0.036
Mouse
negative regulation of leukocyte apoptotic process GO:2000107 31 0.036
sodium ion transport GO:0006814 73 0.036
monocarboxylic acid metabolic process GO:0032787 191 0.036
cellular metal ion homeostasis GO:0006875 151 0.036
tissue homeostasis GO:0001894 115 0.036
Mouse
interleukin 8 production GO:0032637 4 0.035
detection of fungus GO:0016046 2 0.035
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.035
lymphocyte activation involved in immune response GO:0002285 93 0.035
regulation of hydrolase activity GO:0051336 246 0.035
pallium development GO:0021543 120 0.035
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
learning GO:0007612 98 0.034
regulation of vasculature development GO:1901342 88 0.034
Mouse
lymphocyte migration GO:0072676 26 0.034
oligodendrocyte differentiation GO:0048709 53 0.034
negative regulation of phosphorylation GO:0042326 166 0.034
cell maturation GO:0048469 127 0.034
Mouse
osteoclast differentiation GO:0030316 62 0.033
Mouse
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.033
gland development GO:0048732 330 0.033
Mouse Fly
regulation of acute inflammatory response GO:0002673 27 0.033
cellular response to hormone stimulus GO:0032870 150 0.033
Mouse Rat Fly
positive regulation of activation of membrane attack complex GO:0001970 2 0.033
cellular amine metabolic process GO:0044106 44 0.033
positive regulation of jnk cascade GO:0046330 46 0.032
developmental cell growth GO:0048588 84 0.032
organophosphate catabolic process GO:0046434 232 0.032
immune complex clearance by monocytes and macrophages GO:0002436 2 0.032
muscle cell differentiation GO:0042692 261 0.032
Mouse
protein maturation GO:0051604 176 0.032
cellular glucan metabolic process GO:0006073 32 0.032
regulation of neutrophil chemotaxis GO:0090022 14 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
positive regulation of calcium ion transport GO:0051928 27 0.032
Mouse
regulation of secretion GO:0051046 274 0.031
glucose transport GO:0015758 56 0.031
negative regulation of leukocyte mediated immunity GO:0002704 29 0.031
single organism nuclear import GO:1902593 95 0.031
positive regulation of thymocyte migration GO:2000412 2 0.031
stress activated mapk cascade GO:0051403 80 0.031
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.031
Mouse Fly
skeletal muscle organ development GO:0060538 163 0.031
erk1 and erk2 cascade GO:0070371 77 0.030
Mouse
regulation of humoral immune response GO:0002920 22 0.030
heart process GO:0003015 94 0.030
ribonucleotide metabolic process GO:0009259 291 0.030
regulation of myeloid cell differentiation GO:0045637 96 0.030
ribose phosphate metabolic process GO:0019693 291 0.029
cellular response to growth factor stimulus GO:0071363 197 0.029
Mouse
interleukin 1 secretion GO:0050701 16 0.029
digestive system development GO:0055123 200 0.029
Mouse Fly
oxidation reduction process GO:0055114 342 0.029
organelle fission GO:0048285 170 0.029
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.029
anion transport GO:0006820 177 0.029
response to reactive oxygen species GO:0000302 56 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
reactive oxygen species biosynthetic process GO:1903409 8 0.028
branching morphogenesis of an epithelial tube GO:0048754 159 0.028
Mouse
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.028
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.028
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
t cell receptor signaling pathway GO:0050852 46 0.028
locomotory behavior GO:0007626 195 0.028
negative regulation of molecular function GO:0044092 258 0.028
regulation of cytoskeleton organization GO:0051493 122 0.028
Mouse
positive regulation of ion transport GO:0043270 65 0.028
Mouse
inflammatory response to antigenic stimulus GO:0002437 30 0.028
peptidyl amino acid modification GO:0018193 336 0.028
cellular chemical homeostasis GO:0055082 215 0.028
natural killer cell mediated immunity GO:0002228 29 0.028
activation of mapk activity GO:0000187 59 0.028
protein import into nucleus GO:0006606 95 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.027
carboxylic acid biosynthetic process GO:0046394 86 0.027
regulation of granulocyte chemotaxis GO:0071622 17 0.027
negative regulation of apoptotic signaling pathway GO:2001234 104 0.027
hematopoietic progenitor cell differentiation GO:0002244 143 0.027
immune complex clearance GO:0002434 2 0.027
inflammatory cell apoptotic process GO:0006925 11 0.027
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.027
positive regulation of behavior GO:0048520 40 0.027
Mouse
positive regulation of intracellular transport GO:0032388 70 0.027
negative regulation of blood vessel morphogenesis GO:2000181 25 0.027
regulation of jnk cascade GO:0046328 62 0.027
urogenital system development GO:0001655 261 0.027
Mouse Fly
response to oxidative stress GO:0006979 123 0.027
multicellular organism growth GO:0035264 161 0.027
purine nucleoside metabolic process GO:0042278 241 0.026
spermatogenesis GO:0007283 284 0.026
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.026
cellular response to molecule of fungal origin GO:0071226 2 0.026
regulation of intracellular protein transport GO:0033157 82 0.026
positive regulation of cardiac muscle cell apoptotic process GO:0010666 3 0.026
positive regulation of glial cell differentiation GO:0045687 21 0.026
fatty acid biosynthetic process GO:0006633 41 0.026
regulation of eosinophil migration GO:2000416 2 0.026
myotube differentiation GO:0014902 105 0.025
negative regulation of lymphocyte proliferation GO:0050672 45 0.025
regulation of bone remodeling GO:0046850 28 0.025
regulation of purine nucleotide metabolic process GO:1900542 169 0.025
bone resorption GO:0045453 38 0.025
granulocyte differentiation GO:0030851 17 0.025
energy derivation by oxidation of organic compounds GO:0015980 77 0.025
regulation of thymocyte migration GO:2000410 2 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
positive regulation of proteolysis GO:0045862 85 0.025
regulation of actin filament based process GO:0032970 99 0.025
Mouse
regulation of angiogenesis GO:0045765 81 0.025
Mouse
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.025
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.025
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.024
positive regulation of vasoconstriction GO:0045907 4 0.024

Flt3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease by infectious agent DOID:0050117 0 0.313
viral infectious disease DOID:934 0 0.313
acquired immunodeficiency syndrome DOID:635 0 0.192
human immunodeficiency virus infectious disease DOID:526 0 0.192
immune system disease DOID:2914 0 0.076
disease of anatomical entity DOID:7 0 0.076
cancer DOID:162 0 0.038
Human
disease of cellular proliferation DOID:14566 0 0.038
Human
central nervous system disease DOID:331 0 0.035
nervous system disease DOID:863 0 0.035
organ system cancer DOID:0050686 0 0.026
Human