Mus musculus

60 known processes

Mettl3

methyltransferase like 3

(Aliases: Spo8,M6A,2310024F18Rik)

Mettl3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
apoptotic signaling pathway GO:0097190 306 0.079
cellular amino acid metabolic process GO:0006520 103 0.076
rna processing GO:0006396 105 0.063
rna 3 end processing GO:0031123 20 0.058
regulation of cellular amino acid metabolic process GO:0006521 5 0.057
regulation of cellular ketone metabolic process GO:0010565 66 0.052
cellular ketone metabolic process GO:0042180 84 0.045
organelle assembly GO:0070925 177 0.044
amine metabolic process GO:0009308 45 0.043
cellular hyperosmotic salinity response GO:0071475 0 0.043
cellular nitrogen compound catabolic process GO:0044270 280 0.040
mrna processing GO:0006397 63 0.040
heterocycle catabolic process GO:0046700 280 0.039
immune effector process GO:0002252 321 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.035
cellular amine metabolic process GO:0044106 44 0.035
regulation of organelle organization GO:0033043 289 0.034
posttranscriptional regulation of gene expression GO:0010608 155 0.032
somatic diversification of immune receptors GO:0002200 53 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
negative regulation of cell proliferation GO:0008285 296 0.031
lymphocyte mediated immunity GO:0002449 139 0.028
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.028
mrna 3 end processing GO:0031124 16 0.027
dna metabolic process GO:0006259 303 0.026
adaptive immune response GO:0002250 155 0.026
covalent chromatin modification GO:0016569 163 0.025
mrna metabolic process GO:0016071 84 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
muscle tissue development GO:0060537 308 0.024
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.023
cellular response to dna damage stimulus GO:0006974 207 0.023
leukocyte mediated immunity GO:0002443 174 0.023
somatic diversification of immunoglobulins GO:0016445 43 0.023
hematopoietic progenitor cell differentiation GO:0002244 143 0.022
anatomical structure homeostasis GO:0060249 145 0.021
cell cycle checkpoint GO:0000075 47 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
cell type specific apoptotic process GO:0097285 268 0.021
cell activation involved in immune response GO:0002263 126 0.021
chromatin organization GO:0006325 206 0.020
purine containing compound metabolic process GO:0072521 311 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.019
skeletal muscle organ development GO:0060538 163 0.019
macromolecule catabolic process GO:0009057 281 0.019
intrinsic apoptotic signaling pathway GO:0097193 132 0.019
chiasma assembly GO:0051026 6 0.019
regulation of neuron projection development GO:0010975 169 0.018
positive regulation of cell death GO:0010942 224 0.018
rna phosphodiester bond hydrolysis GO:0090501 19 0.018
ncrna processing GO:0034470 26 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
ncrna 3 end processing GO:0043628 2 0.018
chromatin modification GO:0016568 187 0.018
peptidyl amino acid modification GO:0018193 336 0.018
methylation GO:0032259 134 0.018
immunoglobulin mediated immune response GO:0016064 69 0.018
regulation of cell projection organization GO:0031344 206 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
small gtpase mediated signal transduction GO:0007264 97 0.017
membrane organization GO:0061024 245 0.017
mitotic cell cycle GO:0000278 195 0.017
regulation of neuron differentiation GO:0045664 281 0.017
production of molecular mediator of immune response GO:0002440 103 0.017
somatic cell dna recombination GO:0016444 51 0.017
positive regulation of programmed cell death GO:0043068 218 0.016
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.016
organelle fission GO:0048285 170 0.016
aromatic compound catabolic process GO:0019439 286 0.016
b cell activation GO:0042113 161 0.016
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.016
metaphase plate congression GO:0051310 2 0.016
mrna splicing via spliceosome GO:0000398 43 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
histone modification GO:0016570 159 0.015
regulation of anatomical structure size GO:0090066 178 0.015
negative regulation of molecular function GO:0044092 258 0.015
germ cell development GO:0007281 185 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
neuron death GO:0070997 154 0.015
action potential GO:0001508 78 0.015
leukocyte activation involved in immune response GO:0002366 126 0.014
b cell mediated immunity GO:0019724 71 0.014
organelle localization GO:0051640 179 0.014
rna splicing GO:0008380 54 0.014
transcription from rna polymerase iii promoter GO:0006383 3 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
negative regulation of protein modification process GO:0031400 163 0.014
positive regulation of nervous system development GO:0051962 221 0.014
muscle cell differentiation GO:0042692 261 0.014
positive regulation of protein modification process GO:0031401 299 0.014
cytoplasmic transport GO:0016482 234 0.014
cytokine production GO:0001816 319 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
macromolecule methylation GO:0043414 120 0.013
regulation of cellular response to stress GO:0080135 159 0.013
sensory perception GO:0007600 245 0.013
mitotic cell cycle process GO:1903047 159 0.013
rhythmic process GO:0048511 174 0.013
striated muscle tissue development GO:0014706 293 0.013
b cell activation involved in immune response GO:0002312 50 0.013
regulation of intracellular transport GO:0032386 159 0.013
mapk cascade GO:0000165 281 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
dna repair GO:0006281 107 0.012
negative regulation of cell cycle GO:0045786 123 0.012
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.012
snorna metabolic process GO:0016074 1 0.012
multicellular organismal signaling GO:0035637 91 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
maintenance of location GO:0051235 89 0.012
rna interference GO:0016246 2 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
ras protein signal transduction GO:0007265 77 0.012
positive regulation of cell development GO:0010720 237 0.012
regulation of membrane potential GO:0042391 192 0.012
response to radiation GO:0009314 165 0.012
stem cell differentiation GO:0048863 268 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
negative regulation of cell cycle process GO:0010948 69 0.012
lateral inhibition GO:0046331 1 0.012
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.012
chemotaxis GO:0006935 247 0.012
multicellular organism growth GO:0035264 161 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
cellular response to organonitrogen compound GO:0071417 145 0.011
blood vessel morphogenesis GO:0048514 285 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
carbohydrate metabolic process GO:0005975 230 0.011
response to organonitrogen compound GO:0010243 246 0.011
regulation of cell cycle process GO:0010564 160 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.011
locomotory behavior GO:0007626 195 0.011
nuclear division GO:0000280 158 0.011
neuron apoptotic process GO:0051402 142 0.011
fertilization GO:0009566 127 0.011
oxidation reduction process GO:0055114 342 0.011
nucleoside metabolic process GO:0009116 246 0.011
gene silencing GO:0016458 38 0.011
regulation of protein transport GO:0051223 163 0.011
cellular homeostasis GO:0019725 240 0.011
organism emergence from protective structure GO:0071684 4 0.011
immunoglobulin production GO:0002377 73 0.010
cation transmembrane transport GO:0098655 266 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
regulation of transferase activity GO:0051338 263 0.010
protein localization to membrane GO:0072657 108 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
regulation of kinase activity GO:0043549 249 0.010

Mettl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.010
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010