Mus musculus

66 known processes

Unc5d

unc-5 homolog D (C. elegans)

(Aliases: mKIAA1777,KIAA1777,D930029E11Rik,Unc5h4)

Unc5d biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatogenesis GO:0007283 284 0.075
regulation of membrane potential GO:0042391 192 0.073
axonogenesis GO:0007409 274 0.071
hormone secretion GO:0046879 128 0.058
multicellular organism growth GO:0035264 161 0.058
regulation of secretion GO:0051046 274 0.051
action potential GO:0001508 78 0.047
single organismal cell cell adhesion GO:0016337 131 0.047
ras protein signal transduction GO:0007265 77 0.047
forebrain development GO:0030900 302 0.046
response to organonitrogen compound GO:0010243 246 0.045
small gtpase mediated signal transduction GO:0007264 97 0.044
multicellular organismal signaling GO:0035637 91 0.044
cellular ketone metabolic process GO:0042180 84 0.043
regulation of synaptic plasticity GO:0048167 87 0.042
single organism cell adhesion GO:0098602 156 0.042
cell adhesion GO:0007155 329 0.042
ribonucleotide metabolic process GO:0009259 291 0.042
mapk cascade GO:0000165 281 0.041
spermatid differentiation GO:0048515 115 0.039
carbohydrate homeostasis GO:0033500 128 0.039
nitrogen compound transport GO:0071705 271 0.036
amine metabolic process GO:0009308 45 0.036
macromolecule catabolic process GO:0009057 281 0.036
Worm
sensory organ morphogenesis GO:0090596 242 0.036
oxidation reduction process GO:0055114 342 0.035
developmental growth involved in morphogenesis GO:0060560 138 0.035
Worm
cellular lipid metabolic process GO:0044255 323 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
cognition GO:0050890 149 0.034
cellular homeostasis GO:0019725 240 0.034
regulation of system process GO:0044057 200 0.033
transmembrane transport GO:0055085 412 0.033
regulation of ion transport GO:0043269 215 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
nucleotide metabolic process GO:0009117 332 0.032
purine containing compound metabolic process GO:0072521 311 0.032
negative regulation of intracellular signal transduction GO:1902532 167 0.032
g protein coupled receptor signaling pathway GO:0007186 243 0.032
ribose phosphate metabolic process GO:0019693 291 0.032
regulation of cell projection organization GO:0031344 206 0.032
Worm
purine ribonucleotide metabolic process GO:0009150 290 0.032
regulation of secretion by cell GO:1903530 249 0.031
camera type eye development GO:0043010 266 0.031
cellular chemical homeostasis GO:0055082 215 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
transmission of nerve impulse GO:0019226 76 0.030
erk1 and erk2 cascade GO:0070371 77 0.030
cation transport GO:0006812 399 0.029
regulation of mapk cascade GO:0043408 248 0.029
amide transport GO:0042886 138 0.029
sensory perception GO:0007600 245 0.029
peptide transport GO:0015833 133 0.029
regulation of hormone levels GO:0010817 211 0.029
glucose homeostasis GO:0042593 128 0.029
cellular carbohydrate metabolic process GO:0044262 119 0.028
regulation of cellular ketone metabolic process GO:0010565 66 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
synaptic transmission GO:0007268 329 0.027
cellular amine metabolic process GO:0044106 44 0.027
monocarboxylic acid metabolic process GO:0032787 191 0.027
peptidyl amino acid modification GO:0018193 336 0.027
angiogenesis GO:0001525 201 0.027
carbohydrate metabolic process GO:0005975 230 0.027
male gamete generation GO:0048232 285 0.026
ion transmembrane transport GO:0034220 361 0.026
regulation of peptide secretion GO:0002791 77 0.026
positive regulation of mapk cascade GO:0043410 170 0.026
learning or memory GO:0007611 148 0.026
inorganic ion transmembrane transport GO:0098660 234 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
regulation of neuron differentiation GO:0045664 281 0.026
Worm
developmental maturation GO:0021700 193 0.025
telencephalon development GO:0021537 186 0.025
cellular amino acid metabolic process GO:0006520 103 0.025
protein catabolic process GO:0030163 221 0.025
Worm
regulation of cellular component biogenesis GO:0044087 181 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
regulation of cellular catabolic process GO:0031329 242 0.025
heterocycle catabolic process GO:0046700 280 0.025
aromatic compound catabolic process GO:0019439 286 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.024
regulation of transmembrane transport GO:0034762 128 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
germ cell development GO:0007281 185 0.023
regulation of neuron death GO:1901214 134 0.023
renal system development GO:0072001 225 0.023
neuromuscular process GO:0050905 99 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
peptide hormone secretion GO:0030072 109 0.022
regulation of peptide hormone secretion GO:0090276 75 0.022
epithelial cell proliferation GO:0050673 174 0.022
regulation of neuron projection development GO:0010975 169 0.022
Worm
regulation of kinase activity GO:0043549 249 0.022
regionalization GO:0003002 337 0.021
Fly
apoptotic signaling pathway GO:0097190 306 0.021
neuronal action potential GO:0019228 54 0.021
cation homeostasis GO:0055080 212 0.021
glucose metabolic process GO:0006006 92 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
peptide secretion GO:0002790 114 0.021
synapse organization GO:0050808 125 0.020
cell maturation GO:0048469 127 0.020
sensory system development GO:0048880 3 0.020
regulation of hormone secretion GO:0046883 88 0.020
cation transmembrane transport GO:0098655 266 0.020
positive regulation of peptide hormone secretion GO:0090277 31 0.020
regulation of transferase activity GO:0051338 263 0.020
neuron neuron synaptic transmission GO:0007270 69 0.020
regulation of anatomical structure size GO:0090066 178 0.020
Worm
endocytosis GO:0006897 168 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
regulation of protein kinase activity GO:0045859 232 0.020
regulation of cell cycle GO:0051726 281 0.019
locomotory behavior GO:0007626 195 0.019
morphogenesis of a branching structure GO:0001763 203 0.019
calcium ion homeostasis GO:0055074 127 0.019
response to light stimulus GO:0009416 135 0.019
organophosphate biosynthetic process GO:0090407 122 0.019
regulation of proteolysis GO:0030162 164 0.019
second messenger mediated signaling GO:0019932 73 0.019
stem cell development GO:0048864 219 0.019
maintenance of location GO:0051235 89 0.019
regulation of peptide transport GO:0090087 91 0.019
epithelial cell development GO:0002064 159 0.019
positive regulation of hormone secretion GO:0046887 38 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
negative regulation of neuron death GO:1901215 98 0.018
central nervous system neuron differentiation GO:0021953 162 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
myeloid cell differentiation GO:0030099 233 0.018
insulin secretion GO:0030073 89 0.018
positive regulation of secretion GO:0051047 130 0.018
cell type specific apoptotic process GO:0097285 268 0.018
nucleoside metabolic process GO:0009116 246 0.018
organelle localization GO:0051640 179 0.018
gland development GO:0048732 330 0.018
Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
digestive system development GO:0055123 200 0.018
Worm
ribonucleoside metabolic process GO:0009119 245 0.018
muscle tissue development GO:0060537 308 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
striated muscle tissue development GO:0014706 293 0.017
positive regulation of nervous system development GO:0051962 221 0.017
Worm
lateral inhibition GO:0046331 1 0.017
neuron migration GO:0001764 122 0.017
neuron apoptotic process GO:0051402 142 0.017
membrane organization GO:0061024 245 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
negative regulation of cell development GO:0010721 169 0.017
cell division GO:0051301 120 0.017
positive regulation of protein modification process GO:0031401 299 0.017
cytokine production GO:0001816 319 0.017
lipid localization GO:0010876 126 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
spermatid development GO:0007286 108 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
single fertilization GO:0007338 82 0.017
positive regulation of neuron differentiation GO:0045666 141 0.017
Worm
urogenital system development GO:0001655 261 0.017
circulatory system process GO:0003013 197 0.017
negative regulation of neuron apoptotic process GO:0043524 92 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
regulation of erk1 and erk2 cascade GO:0070372 71 0.016
regulation of neuronal synaptic plasticity GO:0048168 30 0.016
smoothened signaling pathway GO:0007224 105 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
response to radiation GO:0009314 165 0.016
regulation of blood circulation GO:1903522 93 0.016
peptidyl serine modification GO:0018209 83 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
compound eye development GO:0048749 1 0.016
activation of mapk activity GO:0000187 59 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
lymphocyte mediated immunity GO:0002449 139 0.016
regulation of postsynaptic membrane potential GO:0060078 48 0.016
skeletal system development GO:0001501 356 0.016
rap protein signal transduction GO:0032486 3 0.016
nucleotide catabolic process GO:0009166 217 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
regulation of ras protein signal transduction GO:0046578 114 0.015
regulation of homeostatic process GO:0032844 182 0.015
fasciculation of motor neuron axon GO:0097156 2 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
regulation of cell adhesion GO:0030155 154 0.015
response to acid chemical GO:0001101 111 0.015
regulation of vasculature development GO:1901342 88 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
regulation of organelle organization GO:0033043 289 0.015
organophosphate catabolic process GO:0046434 232 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
cell substrate adhesion GO:0031589 130 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
cell recognition GO:0008037 83 0.015
respiratory system development GO:0060541 190 0.015
learning GO:0007612 98 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
neuron death GO:0070997 154 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
regulation of map kinase activity GO:0043405 120 0.015
respiratory tube development GO:0030323 167 0.015
generation of precursor metabolites and energy GO:0006091 103 0.015
regulation of feeding behavior GO:0060259 3 0.015
regulation of protein catabolic process GO:0042176 108 0.015
fat cell differentiation GO:0045444 160 0.015
lipid transport GO:0006869 98 0.014
oocyte axis specification GO:0007309 2 0.014
purine nucleotide biosynthetic process GO:0006164 65 0.014
fertilization GO:0009566 127 0.014
regulation of glutamate receptor signaling pathway GO:1900449 16 0.014
protein localization to organelle GO:0033365 185 0.014
positive regulation of kinase activity GO:0033674 155 0.014
negative regulation of molecular function GO:0044092 258 0.014
exocytosis GO:0006887 121 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
dendrite development GO:0016358 115 0.014
Worm
skin development GO:0043588 220 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
leukocyte differentiation GO:0002521 342 0.014
cell fate commitment GO:0045165 210 0.014
regulation of angiogenesis GO:0045765 81 0.014
wnt signaling pathway GO:0016055 188 0.014
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.014
blood circulation GO:0008015 195 0.014
purine containing compound biosynthetic process GO:0072522 70 0.014
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.014
establishment of organelle localization GO:0051656 122 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.014
regulation of protein localization GO:0032880 231 0.014
microtubule based process GO:0007017 236 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
cellular ion homeostasis GO:0006873 165 0.014
oocyte construction GO:0007308 2 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
pallium development GO:0021543 120 0.014
muscle cell differentiation GO:0042692 261 0.013
glycogen metabolic process GO:0005977 32 0.013
positive regulation of cell development GO:0010720 237 0.013
Worm
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.013
protein maturation GO:0051604 176 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
endomembrane system organization GO:0010256 147 0.013
chemotaxis GO:0006935 247 0.013
positive regulation of transferase activity GO:0051347 167 0.013
protein localization to membrane GO:0072657 108 0.013
lung development GO:0030324 164 0.013
regulation of cell migration GO:0030334 219 0.013
positive regulation of fatty acid oxidation GO:0046321 4 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
cranial nerve development GO:0021545 41 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
stem cell differentiation GO:0048863 268 0.013
innate immune response GO:0045087 157 0.013
inorganic cation transmembrane transport GO:0098662 207 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.012
immune effector process GO:0002252 321 0.012
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
metal ion homeostasis GO:0055065 189 0.012
regulation of cytokine production GO:0001817 266 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
terminal button organization GO:0072553 3 0.012
regulation of cellular response to stress GO:0080135 159 0.012
cellular glucose homeostasis GO:0001678 52 0.012
skeletal system morphogenesis GO:0048705 203 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
monosaccharide metabolic process GO:0005996 106 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
wound healing GO:0042060 157 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
tissue homeostasis GO:0001894 115 0.012
calcium ion dependent exocytosis GO:0017156 35 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
organelle assembly GO:0070925 177 0.012
ear development GO:0043583 200 0.012
purine containing compound catabolic process GO:0072523 213 0.012
bone development GO:0060348 120 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
fatty acid metabolic process GO:0006631 121 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
establishment or maintenance of cell polarity GO:0007163 86 0.012
developmental cell growth GO:0048588 84 0.012
Worm
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
energy reserve metabolic process GO:0006112 39 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
stem cell maintenance GO:0019827 130 0.012
blood vessel morphogenesis GO:0048514 285 0.012
polysaccharide metabolic process GO:0005976 39 0.012
retina development in camera type eye GO:0060041 119 0.012
regulation of cell size GO:0008361 72 0.012
Worm
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
multicellular organismal response to stress GO:0033555 62 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
cellularization GO:0007349 1 0.012
somatotropin secreting cell development GO:0060133 2 0.012
membrane depolarization GO:0051899 64 0.012
regulation of inositol trisphosphate biosynthetic process GO:0032960 3 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.011
muscle system process GO:0003012 141 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
anatomical structure homeostasis GO:0060249 145 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
cellular polysaccharide metabolic process GO:0044264 38 0.011
regulation of response to wounding GO:1903034 189 0.011
negative regulation of nervous system development GO:0051961 156 0.011
cellular response to glucose stimulus GO:0071333 45 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
intracellular mrna localization GO:0008298 4 0.011
adiponectin secretion GO:0070162 2 0.011
cellular protein complex assembly GO:0043623 116 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.011
ribose phosphate biosynthetic process GO:0046390 59 0.011
glucan metabolic process GO:0044042 32 0.011
cellular glucan metabolic process GO:0006073 32 0.011
epidermis development GO:0008544 187 0.011
synaptic vesicle transport GO:0048489 57 0.011
cellular response to ammonium ion GO:0071242 2 0.011
adult behavior GO:0030534 135 0.011
dna metabolic process GO:0006259 303 0.011
glutamate receptor signaling pathway GO:0007215 35 0.011
neuron projection guidance GO:0097485 141 0.011
lateral line system development GO:0048925 1 0.011
inter male aggressive behavior GO:0002121 3 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.011
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.011
response to monosaccharide GO:0034284 67 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
engulfment of apoptotic cell GO:0043652 3 0.010
cellular response to monosaccharide stimulus GO:0071326 47 0.010
homeostasis of number of cells GO:0048872 210 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
energy derivation by oxidation of organic compounds GO:0015980 77 0.010
positive regulation of insulin secretion GO:0032024 26 0.010
somatotropin secreting cell differentiation GO:0060126 4 0.010
establishment of vesicle localization GO:0051650 81 0.010
leukocyte mediated immunity GO:0002443 174 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
cellular response to hexose stimulus GO:0071331 47 0.010
sensory perception of sound GO:0007605 97 0.010
positive regulation of map kinase activity GO:0043406 84 0.010
regulation of hydrolase activity GO:0051336 246 0.010
rhythmic process GO:0048511 174 0.010
telencephalon cell migration GO:0022029 55 0.010
hexose transport GO:0008645 56 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
regulation of cell substrate adhesion GO:0010810 73 0.010
nucleoside catabolic process GO:0009164 206 0.010
protein processing GO:0016485 163 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
regulation of multi organism process GO:0043900 111 0.010

Unc5d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012