Mus musculus

11 known processes

Cxcl2

chemokine (C-X-C motif) ligand 2

(Aliases: Scyb2,Scyb,MIP-2a,GROb,Mgsa-b,Mip2,CINC-2a,Gro2,MIP-2)

Cxcl2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.996
Mouse
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.974
Mouse
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.958
Mouse
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.949
regulation of chemokine production GO:0032642 30 0.942
Mouse
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.936
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.918
inflammatory response GO:0006954 244 0.883
Mouse
neutrophil chemotaxis GO:0030593 36 0.868
Mouse Rat
cellular response to lipopolysaccharide GO:0071222 77 0.860
Rat
positive regulation of defense response GO:0031349 124 0.854
Mouse
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.851
inflammatory response to wounding GO:0090594 4 0.838
chemotaxis GO:0006935 247 0.824
Mouse Rat
positive regulation of cytokine production GO:0001819 174 0.805
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.802
Mouse
granulocyte chemotaxis GO:0071621 39 0.794
Mouse Rat
wound healing GO:0042060 157 0.783
Rat
regulation of neutrophil mediated killing of bacterium GO:0070950 1 0.773
Mouse
response to lipopolysaccharide GO:0032496 128 0.771
Mouse Rat
regulation of thymocyte migration GO:2000410 2 0.769
response to molecule of bacterial origin GO:0002237 143 0.766
positive regulation of leukocyte differentiation GO:1902107 86 0.761
regulation of neutrophil mediated cytotoxicity GO:0070948 2 0.758
Mouse
wound healing involved in inflammatory response GO:0002246 4 0.756
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.748
dendritic cell dendrite assembly GO:0097026 2 0.735
thymocyte migration GO:0072679 2 0.729
positive regulation of thymocyte migration GO:2000412 2 0.722
natural killer cell chemotaxis GO:0035747 1 0.718
positive regulation of b cell chemotaxis GO:2000538 2 0.705
leukocyte migration GO:0050900 124 0.705
Mouse Rat
positive regulation of monocyte chemotaxis GO:0090026 2 0.695
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.681
neutrophil migration GO:1990266 37 0.673
Mouse Rat
positive regulation of hematopoietic stem cell proliferation GO:1902035 2 0.664
Mouse
t helper 2 cell cytokine production GO:0035745 4 0.659
defense response to other organism GO:0098542 197 0.646
Mouse
positive regulation of neutrophil mediated killing of fungus GO:0070965 1 0.641
Mouse
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.638
positive regulation of apoptotic process GO:0043065 217 0.635
regulation of t helper 1 cell cytokine production GO:2000554 1 0.634
cytokine production GO:0001816 319 0.634
Mouse
cell chemotaxis GO:0060326 81 0.634
Mouse Rat
leukocyte homeostasis GO:0001776 79 0.624
Mouse
positive regulation of programmed cell death GO:0043068 218 0.622
regulation of protein serine threonine kinase activity GO:0071900 157 0.618
neutrophil mediated cytotoxicity GO:0070942 8 0.616
Mouse
granulocyte migration GO:0097530 43 0.610
Mouse Rat
interaction with symbiont GO:0051702 14 0.594
Mouse
positive regulation of type 2 immune response GO:0002830 9 0.592
positive regulation of killing of cells of other organism GO:0051712 3 0.589
Mouse
regulation of cytokine production GO:0001817 266 0.584
Mouse
regulation of b cell chemotaxis GO:2000537 2 0.583
regulation of natural killer cell chemotaxis GO:2000501 1 0.559
disruption by host of symbiont cells GO:0051852 11 0.557
Mouse
interleukin 18 mediated signaling pathway GO:0035655 2 0.554
t helper 1 cell cytokine production GO:0035744 1 0.552
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.551
Mouse
response to interleukin 1 GO:0070555 11 0.551
Rat
leukocyte apoptotic process GO:0071887 71 0.537
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.528
b cell chemotaxis GO:0035754 3 0.528
t cell proliferation GO:0042098 120 0.526
leukocyte differentiation GO:0002521 342 0.518
positive regulation of eosinophil migration GO:2000418 2 0.505
positive regulation of leukocyte mediated immunity GO:0002705 70 0.505
Mouse
regulation of response to wounding GO:1903034 189 0.500
adaptive immune response GO:0002250 155 0.497
defense response to bacterium GO:0042742 119 0.494
Mouse
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.490
connective tissue replacement involved in inflammatory response wound healing GO:0002248 3 0.485
myeloid leukocyte migration GO:0097529 57 0.482
Mouse Rat
regulation of defense response to bacterium GO:1900424 3 0.481
Mouse
leukocyte chemotaxis GO:0030595 69 0.478
Mouse Rat
response to organic cyclic compound GO:0014070 198 0.467
Rat
positive regulation of mapk cascade GO:0043410 170 0.463
positive regulation of inflammatory response GO:0050729 47 0.459
regulation of multi organism process GO:0043900 111 0.456
Mouse
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.455
Mouse
regulation of protein transport GO:0051223 163 0.454
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.447
Mouse
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.445
skeletal muscle organ development GO:0060538 163 0.433
Mouse
immunoglobulin production in mucosal tissue GO:0002426 3 0.429
regulation of monocyte chemotaxis GO:0090025 3 0.426
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.416
modification of morphology or physiology of other organism GO:0035821 18 0.413
Mouse
interleukin 12 secretion GO:0072610 3 0.411
positive regulation of cell killing GO:0031343 33 0.408
Mouse
interspecies interaction between organisms GO:0044419 83 0.407
Mouse
myeloid cell differentiation GO:0030099 233 0.406
t cell activation involved in immune response GO:0002286 43 0.405
cellular response to molecule of bacterial origin GO:0071219 83 0.402
Rat
regulation of neutrophil mediated killing of fungus GO:0070953 1 0.400
Mouse
protein catabolic process GO:0030163 221 0.400
regulation of defense response GO:0031347 233 0.392
Mouse
regulation of mapk cascade GO:0043408 248 0.391
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.385
myeloid leukocyte differentiation GO:0002573 119 0.383
morphogenesis of a branching epithelium GO:0061138 193 0.381
keratinocyte migration GO:0051546 3 0.379
regulation of t helper 2 cell cytokine production GO:2000551 3 0.378
cellular response to biotic stimulus GO:0071216 92 0.370
Rat
negative regulation of cellular protein metabolic process GO:0032269 247 0.359
regulation of t helper 1 cell differentiation GO:0045625 7 0.355
i kappab kinase nf kappab signaling GO:0007249 85 0.352
regulation of cell activation GO:0050865 289 0.340
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.339
Mouse
response to interleukin 4 GO:0070670 23 0.338
positive regulation of cellular amine metabolic process GO:0033240 5 0.334
regulation of cytokine secretion GO:0050707 61 0.334
cdc42 protein signal transduction GO:0032488 0 0.332
regulation of cellular catabolic process GO:0031329 242 0.331
mature natural killer cell chemotaxis GO:0035782 1 0.328
interleukin 1 production GO:0032612 31 0.327
regulation of homeostatic process GO:0032844 182 0.325
positive regulation of cell death GO:0010942 224 0.325
regulation of leukocyte mediated immunity GO:0002703 104 0.318
Mouse
positive regulation of neutrophil chemotaxis GO:0090023 12 0.306
regulation of striated muscle cell differentiation GO:0051153 81 0.303
Mouse
regulation of secretion by cell GO:1903530 249 0.297
cellular amino acid metabolic process GO:0006520 103 0.297
regulation of inflammatory response GO:0050727 147 0.295
positive regulation of immune effector process GO:0002699 107 0.294
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.292
positive regulation of antimicrobial humoral response GO:0002760 2 0.291
regulation of protein localization GO:0032880 231 0.289
killing of cells of other organism GO:0031640 13 0.289
Mouse
innate immune response GO:0045087 157 0.288
t helper 1 cell differentiation GO:0045063 13 0.287
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.282
Mouse
astrocyte cell migration GO:0043615 3 0.281
rho protein signal transduction GO:0007266 32 0.281
jnk cascade GO:0007254 72 0.279
t cell differentiation involved in immune response GO:0002292 30 0.278
modification by host of symbiont morphology or physiology GO:0051851 12 0.276
Mouse
regulation of transferase activity GO:0051338 263 0.274
regulation of ion transport GO:0043269 215 0.274
regulation of cell motility GO:2000145 236 0.272
myoblast differentiation GO:0045445 52 0.269
Mouse
regulation of eosinophil migration GO:2000416 2 0.268
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.268
protein secretion GO:0009306 111 0.267
alpha beta t cell activation GO:0046631 91 0.266
regulation of establishment of protein localization GO:0070201 181 0.262
regulation of cellular amino acid metabolic process GO:0006521 5 0.262
t helper cell differentiation GO:0042093 28 0.262
regulation of response to biotic stimulus GO:0002831 38 0.259
Mouse
antibacterial peptide secretion GO:0002779 1 0.258
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.257
skeletal muscle fiber development GO:0048741 58 0.254
Mouse
myotube cell development GO:0014904 60 0.254
Mouse
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.251
Mouse
macromolecule catabolic process GO:0009057 281 0.250
regulation of rho gtpase activity GO:0032319 58 0.250
regulation of myotube differentiation GO:0010830 62 0.243
Mouse
alpha beta t cell activation involved in immune response GO:0002287 31 0.243
negative regulation of molecular function GO:0044092 258 0.243
cellular amine metabolic process GO:0044106 44 0.242
regulation of killing of cells of other organism GO:0051709 4 0.242
Mouse
regulation of kinase activity GO:0043549 249 0.242
t cell activation GO:0042110 289 0.241
regulation of dendritic cell dendrite assembly GO:2000547 2 0.240
neutrophil mediated killing of fungus GO:0070947 3 0.238
Mouse
t cell differentiation GO:0030217 174 0.237
regulation of secretion GO:0051046 274 0.236
sequestering of calcium ion GO:0051208 18 0.236
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.235
cellular response to lipid GO:0071396 145 0.235
Rat
positive regulation of myotube differentiation GO:0010831 24 0.235
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.233
Rat
positive regulation of secretion GO:0051047 130 0.233
gland development GO:0048732 330 0.233
regulation of reactive oxygen species metabolic process GO:2000377 40 0.224
Mouse
regulation of hydrolase activity GO:0051336 246 0.223
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.221
Mouse
positive regulation of lymphocyte differentiation GO:0045621 61 0.218
hematopoietic stem cell proliferation GO:0071425 13 0.218
Mouse
toll like receptor 4 signaling pathway GO:0034142 9 0.216
organic anion transport GO:0015711 137 0.214
positive regulation of t cell differentiation GO:0045582 52 0.214
regulation of map kinase activity GO:0043405 120 0.212
cellular response to organic cyclic compound GO:0071407 87 0.212
negative regulation of intracellular signal transduction GO:1902532 167 0.211
negative regulation of cell proliferation GO:0008285 296 0.209
regulation of lymphocyte differentiation GO:0045619 107 0.208
tumor necrosis factor production GO:0032640 50 0.207
immune effector process GO:0002252 321 0.206
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.206
positive regulation of cytokine production involved in immune response GO:0002720 19 0.206
positive regulation of muscle cell differentiation GO:0051149 39 0.204
Mouse
regulation of adiponectin secretion GO:0070163 2 0.204
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.203
positive regulation of cell activation GO:0050867 158 0.202
regulation of leukocyte apoptotic process GO:2000106 56 0.201
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.201
regulation of jun kinase activity GO:0043506 40 0.200
positive regulation of granulocyte chemotaxis GO:0071624 12 0.200
muscle tissue development GO:0060537 308 0.200
Mouse
epithelial cell proliferation GO:0050673 174 0.200
mature dendritic cell differentiation GO:0097029 3 0.199
negative regulation of muscle cell differentiation GO:0051148 33 0.197
Mouse
sequestering of metal ion GO:0051238 19 0.196
positive regulation of innate immune response GO:0045089 80 0.195
negative regulation of macrophage apoptotic process GO:2000110 3 0.195
negative regulation of map kinase activity GO:0043407 34 0.194
regulation of insulin receptor signaling pathway GO:0046626 21 0.191
regulation of t cell activation GO:0050863 170 0.190
regulation of cellular response to stress GO:0080135 159 0.189
regulation of cytokine biosynthetic process GO:0042035 59 0.188
amide transport GO:0042886 138 0.186
morphogenesis of a branching structure GO:0001763 203 0.186
cellular chemical homeostasis GO:0055082 215 0.185
Rat
positive regulation of t cell activation GO:0050870 101 0.185
leukocyte mediated immunity GO:0002443 174 0.184
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.183
amine metabolic process GO:0009308 45 0.183
regulation of apoptotic signaling pathway GO:2001233 197 0.181
organ or tissue specific immune response GO:0002251 13 0.180
regulation of interleukin 1 production GO:0032652 26 0.180
epithelial tube morphogenesis GO:0060562 303 0.176
regulation of t cell differentiation GO:0045580 83 0.175
killing by host of symbiont cells GO:0051873 11 0.175
Mouse
single organism cell adhesion GO:0098602 156 0.175
regulation of leukocyte differentiation GO:1902105 159 0.175
myotube differentiation GO:0014902 105 0.175
Mouse
positive regulation of cytokine secretion GO:0050715 41 0.173
chemokine production GO:0032602 34 0.171
Mouse
activation of innate immune response GO:0002218 56 0.171
t helper 1 type immune response GO:0042088 25 0.169
negative regulation of viral transcription GO:0032897 3 0.168
antimicrobial peptide production GO:0002775 2 0.167
response to transforming growth factor beta GO:0071559 88 0.165
syncytium formation by plasma membrane fusion GO:0000768 42 0.165
Mouse
regulation of protein kinase activity GO:0045859 232 0.164
regulation of tumor necrosis factor production GO:0032680 49 0.164
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.164
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.163
adiponectin secretion GO:0070162 2 0.160
carboxylic acid transport GO:0046942 100 0.159
mapk cascade GO:0000165 281 0.158
regulation of cell migration GO:0030334 219 0.156
cytokine secretion GO:0050663 72 0.155
production of molecular mediator of immune response GO:0002440 103 0.155
positive regulation of jun kinase activity GO:0043507 30 0.155
extrinsic apoptotic signaling pathway GO:0097191 126 0.155
cell activation involved in immune response GO:0002263 126 0.153
response to organonitrogen compound GO:0010243 246 0.153
Rat
cellular homeostasis GO:0019725 240 0.150
Rat
positive regulation of secretion by cell GO:1903532 114 0.149
response to atp GO:0033198 8 0.146
muscle cell development GO:0055001 133 0.146
Mouse
stress activated protein kinase signaling cascade GO:0031098 81 0.146
antibacterial peptide production GO:0002778 2 0.146
positive regulation of cd4 positive alpha beta t cell activation GO:2000516 16 0.145
cellular ketone metabolic process GO:0042180 84 0.145
anion transport GO:0006820 177 0.144
eosinophil migration GO:0072677 3 0.144
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.142
positive regulation of chemokine biosynthetic process GO:0045080 6 0.141
defense response to gram positive bacterium GO:0050830 50 0.141
peptide secretion GO:0002790 114 0.139
neutrophil mediated killing of symbiont cell GO:0070943 8 0.138
Mouse
apoptotic signaling pathway GO:0097190 306 0.138
alpha beta t cell proliferation GO:0046633 21 0.138
cellular response to organonitrogen compound GO:0071417 145 0.138
regulation of angiogenesis GO:0045765 81 0.138
myeloid cell apoptotic process GO:0033028 22 0.138
gtp catabolic process GO:0006184 143 0.137
lymphocyte activation involved in immune response GO:0002285 93 0.137
defense response to gram negative bacterium GO:0050829 28 0.133
Mouse
myeloid leukocyte activation GO:0002274 83 0.132
antibacterial peptide biosynthetic process GO:0002780 2 0.131
ras protein signal transduction GO:0007265 77 0.131
regulation of chemokine secretion GO:0090196 4 0.131
cell recognition GO:0008037 83 0.130
cell type specific apoptotic process GO:0097285 268 0.130
chemokine metabolic process GO:0050755 10 0.129
forebrain development GO:0030900 302 0.128
response to tumor necrosis factor GO:0034612 26 0.128
positive regulation of interleukin 1 secretion GO:0050716 14 0.128
regulation of t helper cell differentiation GO:0045622 14 0.127
positive regulation of chemokine production GO:0032722 22 0.127
dendritic cell differentiation GO:0097028 26 0.126
negative regulation of phosphorylation GO:0042326 166 0.124
regulation of lymphocyte activation GO:0051249 240 0.123
lymphocyte differentiation GO:0030098 242 0.123
positive regulation of epithelial cell proliferation GO:0050679 68 0.123
positive regulation of protein modification process GO:0031401 299 0.122
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.122
regulation of cell projection assembly GO:0060491 38 0.122
regulation of jnk cascade GO:0046328 62 0.122
regulation of chemotaxis GO:0050920 53 0.121
regulation of fatty acid transport GO:2000191 10 0.121
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.121
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.121
striated muscle tissue development GO:0014706 293 0.119
Mouse
blood vessel morphogenesis GO:0048514 285 0.119
positive regulation of lymphocyte proliferation GO:0050671 70 0.118
negative regulation of multi organism process GO:0043901 68 0.117
regulation of cellular amine metabolic process GO:0033238 20 0.117
regulation of hematopoietic stem cell proliferation GO:1902033 3 0.117
Mouse
t cell mediated immunity GO:0002456 50 0.116
positive regulation of striated muscle cell differentiation GO:0051155 35 0.115
Mouse
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.115
Mouse
regulation of neutrophil chemotaxis GO:0090022 14 0.115
branching morphogenesis of an epithelial tube GO:0048754 159 0.115
regulation of skeletal muscle fiber development GO:0048742 36 0.115
Mouse
regulation of immunoglobulin mediated immune response GO:0002889 37 0.115
muscle cell differentiation GO:0042692 261 0.114
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.114
Rat
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.114
positive regulation of response to wounding GO:1903036 66 0.114
regulation of stress activated mapk cascade GO:0032872 69 0.113
antimicrobial peptide biosynthetic process GO:0002777 2 0.113
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.112
positive regulation of t cell cytokine production GO:0002726 5 0.111
cellular response to interleukin 4 GO:0071353 21 0.110
positive regulation of neuron apoptotic process GO:0043525 25 0.110
negative regulation of protein modification process GO:0031400 163 0.110
regulation of membrane potential GO:0042391 192 0.109
response to purine containing compound GO:0014074 28 0.109
regulation of interferon gamma production GO:0032649 57 0.109
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.108
regulation of vascular endothelial growth factor production GO:0010574 13 0.107
positive regulation of angiogenesis GO:0045766 46 0.107
negative regulation of hydrolase activity GO:0051346 71 0.107
regulation of fever generation GO:0031620 6 0.107
acute phase response GO:0006953 10 0.107
metal ion homeostasis GO:0055065 189 0.107
Rat
negative regulation of chemokine production GO:0032682 4 0.107
lymphocyte proliferation GO:0046651 164 0.106
negative regulation of cytokine production GO:0001818 84 0.106
positive regulation of stress activated mapk cascade GO:0032874 48 0.105
release of sequestered calcium ion into cytosol GO:0051209 42 0.105
regulation of t cell proliferation GO:0042129 92 0.105
reactive oxygen species metabolic process GO:0072593 84 0.104
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.104
peptide hormone secretion GO:0030072 109 0.104
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.103
nucleoside metabolic process GO:0009116 246 0.103
activation of jun kinase activity GO:0007257 15 0.103
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.103
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.101
small gtpase mediated signal transduction GO:0007264 97 0.101
regulation of alpha beta t cell proliferation GO:0046640 18 0.101
alpha beta t cell differentiation GO:0046632 69 0.099
regulation of proteolysis GO:0030162 164 0.099
cellular response to interferon gamma GO:0071346 25 0.098
cytoplasmic transport GO:0016482 234 0.098
positive regulation of macrophage chemotaxis GO:0010759 5 0.098
nucleotide metabolic process GO:0009117 332 0.098
angiogenesis GO:0001525 201 0.098
positive regulation of transferase activity GO:0051347 167 0.098
calcium ion transport GO:0006816 159 0.098
negative regulation of secretion GO:0051048 61 0.097
regulation of t cell mediated immunity GO:0002709 34 0.097
regulation of alpha beta t cell activation GO:0046634 53 0.097
interleukin 1 secretion GO:0050701 16 0.097
cytokine biosynthetic process GO:0042089 68 0.096
negative regulation of immune system process GO:0002683 209 0.096
negative regulation of lipid metabolic process GO:0045833 30 0.096
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.095
positive regulation of lymphocyte activation GO:0051251 140 0.095
regulation of cell projection organization GO:0031344 206 0.095
nucleobase containing small molecule metabolic process GO:0055086 352 0.094
monocarboxylic acid transport GO:0015718 44 0.094
mammary gland morphogenesis GO:0060443 54 0.093
divalent inorganic cation homeostasis GO:0072507 138 0.093
Rat
regulation of cell killing GO:0031341 40 0.091
Mouse
regulation of alpha beta t cell differentiation GO:0046637 35 0.091
positive regulation of t helper 1 type immune response GO:0002827 12 0.091
cd4 positive alpha beta t cell activation GO:0035710 45 0.090
negative regulation of phosphate metabolic process GO:0045936 184 0.090
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.089
positive regulation of cd4 positive alpha beta t cell differentiation GO:0043372 14 0.089
positive regulation of endocytosis GO:0045807 42 0.089
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.089
cholesterol metabolic process GO:0008203 56 0.089
ribonucleoside triphosphate metabolic process GO:0009199 220 0.089
regulation of rho protein signal transduction GO:0035023 71 0.088
cellular response to interleukin 18 GO:0071351 3 0.088
prostaglandin transport GO:0015732 7 0.088
positive regulation of cell projection organization GO:0031346 95 0.088
regulation of nucleotide metabolic process GO:0006140 169 0.088
regulation of lipid metabolic process GO:0019216 118 0.087
neutrophil mediated immunity GO:0002446 19 0.087
Mouse
immunoglobulin production GO:0002377 73 0.086
positive regulation of protein phosphorylation GO:0001934 242 0.086
immune response activating signal transduction GO:0002757 116 0.086
regeneration GO:0031099 38 0.085
regulation of innate immune response GO:0045088 91 0.085
peptide transport GO:0015833 133 0.085
cytokine production involved in immune response GO:0002367 34 0.085
interferon gamma production GO:0032609 67 0.085
negative regulation of fat cell differentiation GO:0045599 36 0.084
positive regulation of protein transport GO:0051222 93 0.084
single organismal cell cell adhesion GO:0016337 131 0.084
muscle fiber development GO:0048747 76 0.084
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.084
nucleoside phosphate metabolic process GO:0006753 338 0.083
positive regulation of t helper cell differentiation GO:0045624 9 0.083
detection of fungus GO:0016046 2 0.082
negative regulation of striated muscle cell differentiation GO:0051154 14 0.082
Mouse
b cell mediated immunity GO:0019724 71 0.081
leukocyte activation involved in immune response GO:0002366 126 0.081
cellular response to growth factor stimulus GO:0071363 197 0.081
positive regulation of cellular catabolic process GO:0031331 148 0.080
positive regulation of interleukin 12 production GO:0032735 21 0.079
striated muscle cell development GO:0055002 125 0.079
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.079
positive regulation of leukocyte proliferation GO:0070665 73 0.078
ribonucleoside metabolic process GO:0009119 245 0.078
reactive nitrogen species metabolic process GO:2001057 0 0.078
regulation of antimicrobial humoral response GO:0002759 3 0.078
cellular response to interleukin 1 GO:0071347 8 0.078
Rat
regulation of t helper 1 type immune response GO:0002825 17 0.078
positive regulation of nucleotide metabolic process GO:0045981 114 0.078
regulation of interleukin 6 production GO:0032675 55 0.077
stress activated mapk cascade GO:0051403 80 0.077
chemokine biosynthetic process GO:0042033 8 0.077
response to inorganic substance GO:0010035 96 0.077
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.077
regulation of myoblast differentiation GO:0045661 29 0.077
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.077
regulation of epithelial cell proliferation GO:0050678 141 0.077
regulation of neutrophil migration GO:1902622 14 0.076
response to growth factor GO:0070848 198 0.076
glycosyl compound metabolic process GO:1901657 246 0.075
cellular response to steroid hormone stimulus GO:0071383 33 0.075
response to extracellular stimulus GO:0009991 127 0.075
positive regulation of cell motility GO:2000147 116 0.075
guanosine containing compound metabolic process GO:1901068 144 0.075
second messenger mediated signaling GO:0019932 73 0.074
positive regulation of jnk cascade GO:0046330 46 0.074
purine containing compound metabolic process GO:0072521 311 0.074
regulation of hormone levels GO:0010817 211 0.074
positive regulation of chemokine secretion GO:0090197 4 0.074
antimicrobial peptide secretion GO:0002776 1 0.074
positive regulation of coagulation GO:0050820 13 0.074
negative regulation of inflammatory response GO:0050728 61 0.073
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.073
placenta development GO:0001890 140 0.073
cytokine mediated signaling pathway GO:0019221 115 0.072
cellular macromolecule catabolic process GO:0044265 206 0.072
regulation of myeloid cell differentiation GO:0045637 96 0.072
regulation of macrophage chemotaxis GO:0010758 8 0.071
regulation of protein catabolic process GO:0042176 108 0.070
positive regulation of chemotaxis GO:0050921 38 0.070
regulation of cellular ketone metabolic process GO:0010565 66 0.070
nitrogen compound transport GO:0071705 271 0.070
cell cell recognition GO:0009988 44 0.070
positive regulation of nucleotide catabolic process GO:0030813 88 0.070
macrophage chemotaxis GO:0048246 14 0.070
pattern recognition receptor signaling pathway GO:0002221 47 0.070
regulation of interleukin 1 beta production GO:0032651 25 0.069
negative regulation of myoblast differentiation GO:0045662 18 0.069
Mouse
osteoclast differentiation GO:0030316 62 0.069
regulation of immunoglobulin production GO:0002637 42 0.069
positive regulation of map kinase activity GO:0043406 84 0.069
response to organophosphorus GO:0046683 22 0.068
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.068
purine nucleoside triphosphate metabolic process GO:0009144 226 0.067
mammary gland epithelium development GO:0061180 65 0.067
regulation of protein deacetylation GO:0090311 17 0.067
regulation of adrenergic receptor signaling pathway GO:0071877 4 0.067
interleukin 1 mediated signaling pathway GO:0070498 4 0.066
regulation of b cell mediated immunity GO:0002712 37 0.066
regulation of peptide transport GO:0090087 91 0.065
regulation of purine nucleotide catabolic process GO:0033121 122 0.065
regulation of vasculature development GO:1901342 88 0.064
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.064
regulation of plasminogen activation GO:0010755 4 0.063
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.063
cellular response to hormone stimulus GO:0032870 150 0.063
regulation of ras gtpase activity GO:0032318 88 0.062
response to insulin GO:0032868 100 0.062
regulation of ras protein signal transduction GO:0046578 114 0.062
negative regulation of macrophage chemotaxis GO:0010760 1 0.061
cellular divalent inorganic cation homeostasis GO:0072503 127 0.061
Rat
heterocycle catabolic process GO:0046700 280 0.060
positive regulation of behavior GO:0048520 40 0.060
icosanoid transport GO:0071715 14 0.060
regulation of cellular component biogenesis GO:0044087 181 0.060
response to radiation GO:0009314 165 0.060
Rat
peptidyl amino acid modification GO:0018193 336 0.059
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.059
positive regulation of interleukin 1 beta production GO:0032731 16 0.059
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.059
vascular endothelial growth factor production GO:0010573 13 0.059
positive regulation vascular endothelial growth factor production GO:0010575 10 0.059
regulation of muscle tissue development GO:1901861 97 0.059
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.058
regulation of peptidase activity GO:0052547 96 0.058
regulation of neuron apoptotic process GO:0043523 122 0.058
negative regulation of neuron projection regeneration GO:0070571 3 0.058

Cxcl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.138
disease of cellular proliferation DOID:14566 0 0.138