Mus musculus

0 known processes

Sspn

sarcospan

(Aliases: Krag)

Sspn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
extracellular structure organization GO:0043062 148 0.139
regulation of cellular ketone metabolic process GO:0010565 66 0.104
negative regulation of phosphorylation GO:0042326 166 0.072
amine metabolic process GO:0009308 45 0.070
positive regulation of cellular amine metabolic process GO:0033240 5 0.068
regulation of establishment of protein localization GO:0070201 181 0.065
cytoplasmic transport GO:0016482 234 0.064
cellular ketone metabolic process GO:0042180 84 0.059
endomembrane system organization GO:0010256 147 0.059
negative regulation of cellular protein metabolic process GO:0032269 247 0.058
negative regulation of phosphorus metabolic process GO:0010563 184 0.058
membrane organization GO:0061024 245 0.057
cation transport GO:0006812 399 0.057
regulation of cellular amino acid metabolic process GO:0006521 5 0.056
metal ion homeostasis GO:0055065 189 0.056
blood circulation GO:0008015 195 0.055
cellular ion homeostasis GO:0006873 165 0.055
cellular amino acid metabolic process GO:0006520 103 0.054
regulation of protein localization GO:0032880 231 0.051
inorganic ion transmembrane transport GO:0098660 234 0.046
action potential GO:0001508 78 0.046
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
immune effector process GO:0002252 321 0.045
regulation of cell motility GO:2000145 236 0.045
negative regulation of cell proliferation GO:0008285 296 0.044
negative regulation of protein metabolic process GO:0051248 282 0.043
cellular amine metabolic process GO:0044106 44 0.043
regulation of intracellular transport GO:0032386 159 0.042
extracellular matrix organization GO:0030198 147 0.041
cation homeostasis GO:0055080 212 0.041
response to organonitrogen compound GO:0010243 246 0.040
regulation of cell projection organization GO:0031344 206 0.040
regulation of cellular amine metabolic process GO:0033238 20 0.039
cation transmembrane transport GO:0098655 266 0.039
regulation of protein transport GO:0051223 163 0.039
protein localization to membrane GO:0072657 108 0.039
transmembrane transport GO:0055085 412 0.038
circulatory system process GO:0003013 197 0.038
blood vessel morphogenesis GO:0048514 285 0.037
chemotaxis GO:0006935 247 0.036
regulation of intracellular protein transport GO:0033157 82 0.036
skeletal muscle organ development GO:0060538 163 0.035
response to oxidative stress GO:0006979 123 0.035
regulation of secretion GO:0051046 274 0.033
plasma membrane organization GO:0007009 90 0.033
skeletal system development GO:0001501 356 0.032
negative regulation of angiogenesis GO:0016525 25 0.032
negative regulation of blood vessel morphogenesis GO:2000181 25 0.032
positive regulation of programmed cell death GO:0043068 218 0.032
cartilage development GO:0051216 140 0.032
regulation of protein targeting GO:1903533 61 0.031
protein localization to plasma membrane GO:0072659 57 0.031
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.030
peptidyl amino acid modification GO:0018193 336 0.030
muscle tissue development GO:0060537 308 0.030
positive regulation of intracellular transport GO:0032388 70 0.030
cellular response to growth factor stimulus GO:0071363 197 0.030
single organism nuclear import GO:1902593 95 0.029
ion transmembrane transport GO:0034220 361 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
renal system development GO:0072001 225 0.029
reactive nitrogen species metabolic process GO:2001057 0 0.029
inorganic cation transmembrane transport GO:0098662 207 0.028
regulation of cell adhesion GO:0030155 154 0.027
oxidation reduction process GO:0055114 342 0.027
energy derivation by oxidation of organic compounds GO:0015980 77 0.027
regulation of protein kinase b signaling GO:0051896 56 0.027
regulation of cytoplasmic transport GO:1903649 112 0.026
cell substrate adhesion GO:0031589 130 0.026
dephosphorylation GO:0016311 129 0.026
defense response to bacterium GO:0042742 119 0.025
developmental maturation GO:0021700 193 0.025
regulation of secretion by cell GO:1903530 249 0.025
response to growth factor GO:0070848 198 0.025
reactive oxygen species biosynthetic process GO:1903409 8 0.025
camera type eye development GO:0043010 266 0.024
connective tissue development GO:0061448 179 0.024
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.024
protein targeting GO:0006605 143 0.024
nuclear transport GO:0051169 139 0.024
urogenital system development GO:0001655 261 0.024
protein kinase b signaling GO:0043491 74 0.023
actin cytoskeleton organization GO:0030036 220 0.023
negative regulation of molecular function GO:0044092 258 0.023
heart contraction GO:0060047 93 0.023
regulation of system process GO:0044057 200 0.023
regulation of membrane potential GO:0042391 192 0.023
cellular response to lipopolysaccharide GO:0071222 77 0.022
cellular divalent inorganic cation homeostasis GO:0072503 127 0.022
response to organic cyclic compound GO:0014070 198 0.022
cellular chemical homeostasis GO:0055082 215 0.022
regulation of cellular response to growth factor stimulus GO:0090287 82 0.022
generation of precursor metabolites and energy GO:0006091 103 0.022
regulation of cell cycle GO:0051726 281 0.022
carbohydrate metabolic process GO:0005975 230 0.022
divalent inorganic cation homeostasis GO:0072507 138 0.022
regulation of multi organism process GO:0043900 111 0.022
wound healing GO:0042060 157 0.022
muscle cell differentiation GO:0042692 261 0.022
regulation of body fluid levels GO:0050878 162 0.022
retina development in camera type eye GO:0060041 119 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
negative regulation of protein phosphorylation GO:0001933 126 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
intrinsic apoptotic signaling pathway GO:0097193 132 0.021
divalent inorganic cation transport GO:0072511 178 0.021
heart process GO:0003015 94 0.020
metencephalon development GO:0022037 89 0.020
wnt signaling pathway GO:0016055 188 0.020
kidney development GO:0001822 213 0.020
striated muscle contraction GO:0006941 45 0.020
organelle assembly GO:0070925 177 0.020
cellular homeostasis GO:0019725 240 0.020
regulation of cell migration GO:0030334 219 0.020
cellular component assembly involved in morphogenesis GO:0010927 139 0.020
camp metabolic process GO:0046058 40 0.020
termination of rna polymerase i transcription GO:0006363 2 0.020
nuclear import GO:0051170 95 0.020
meiotic cell cycle GO:0051321 122 0.020
multicellular organism growth GO:0035264 161 0.020
positive regulation of protein modification process GO:0031401 299 0.020
sodium ion export GO:0071436 2 0.019
circadian regulation of gene expression GO:0032922 48 0.019
intracellular protein transport GO:0006886 204 0.019
cellular calcium ion homeostasis GO:0006874 119 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
defense response to other organism GO:0098542 197 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.019
mapk cascade GO:0000165 281 0.019
negative regulation of calcium ion transmembrane transporter activity GO:1901020 1 0.019
establishment of protein localization to membrane GO:0090150 54 0.019
regulation of proteolysis GO:0030162 164 0.019
regulation of mitotic cell cycle GO:0007346 126 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
respiratory system development GO:0060541 190 0.018
regulation of homeostatic process GO:0032844 182 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
cellular response to acid chemical GO:0071229 68 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
macromolecule catabolic process GO:0009057 281 0.018
myosin filament assembly GO:0031034 2 0.018
synaptic transmission GO:0007268 329 0.018
sodium ion transmembrane transport GO:0035725 49 0.018
transmission of nerve impulse GO:0019226 76 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
cellular lipid metabolic process GO:0044255 323 0.018
bone development GO:0060348 120 0.018
response to transforming growth factor beta GO:0071559 88 0.017
neuron projection guidance GO:0097485 141 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
heart morphogenesis GO:0003007 178 0.017
regulation of anatomical structure size GO:0090066 178 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
response to inorganic substance GO:0010035 96 0.017
positive regulation of nervous system development GO:0051962 221 0.017
cell adhesion GO:0007155 329 0.017
single organism cell adhesion GO:0098602 156 0.017
transcription initiation from rna polymerase i promoter GO:0006361 4 0.017
gland development GO:0048732 330 0.017
respiratory tube development GO:0030323 167 0.017
vascular process in circulatory system GO:0003018 62 0.017
regulation of transmembrane transport GO:0034762 128 0.017
establishment of protein localization to organelle GO:0072594 118 0.017
microtubule based process GO:0007017 236 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
positive regulation of cell adhesion GO:0045785 80 0.017
striated muscle myosin thick filament assembly GO:0071688 1 0.017
regulation of cell substrate adhesion GO:0010810 73 0.016
ear development GO:0043583 200 0.016
regulation of erk1 and erk2 cascade GO:0070372 71 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
hindbrain development GO:0030902 128 0.016
muscle contraction GO:0006936 101 0.016
muscle system process GO:0003012 141 0.016
regulation of blood pressure GO:0008217 93 0.016
morphogenesis of a branching structure GO:0001763 203 0.016
regulation of feeding behavior GO:0060259 3 0.016
apoptotic signaling pathway GO:0097190 306 0.016
actin filament based movement GO:0030048 23 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.016
nucleobase containing small molecule metabolic process GO:0055086 352 0.016
adaptive immune response GO:0002250 155 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
cytosolic calcium ion homeostasis GO:0051480 70 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
regulation of angiogenesis GO:0045765 81 0.015
anatomical structure homeostasis GO:0060249 145 0.015
regulation of voltage gated calcium channel activity GO:1901385 4 0.015
adult behavior GO:0030534 135 0.015
cellular response to molecule of bacterial origin GO:0071219 83 0.015
regulation of nucleocytoplasmic transport GO:0046822 73 0.015
neuronal action potential GO:0019228 54 0.015
angiogenesis GO:0001525 201 0.015
locomotory behavior GO:0007626 195 0.015
response to extracellular stimulus GO:0009991 127 0.015
regulation of ion transmembrane transporter activity GO:0032412 54 0.015
forebrain development GO:0030900 302 0.015
tissue homeostasis GO:0001894 115 0.015
ras protein signal transduction GO:0007265 77 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
regulation of hormone levels GO:0010817 211 0.015
protein secretion GO:0009306 111 0.015
limb morphogenesis GO:0035108 149 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
negative regulation of protein modification process GO:0031400 163 0.014
striated muscle tissue development GO:0014706 293 0.014
regulation of neurotransmitter levels GO:0001505 87 0.014
potassium ion transport GO:0006813 52 0.014
positive regulation of cell motility GO:2000147 116 0.014
membrane depolarization GO:0051899 64 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
regulation of mapk cascade GO:0043408 248 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
response to oxygen levels GO:0070482 62 0.014
defense response to virus GO:0051607 68 0.014
odontogenesis GO:0042476 78 0.014
negative regulation of protein transport GO:0051224 46 0.014
sequestering of calcium ion GO:0051208 18 0.014
myosin filament organization GO:0031033 3 0.014
lipid localization GO:0010876 126 0.014
i kappab kinase nf kappab signaling GO:0007249 85 0.014
response to light stimulus GO:0009416 135 0.014
regulation of cell cycle process GO:0010564 160 0.014
response to radiation GO:0009314 165 0.014
negative regulation of intracellular transport GO:0032387 38 0.014
regulation of tube size GO:0035150 57 0.014
cilium morphogenesis GO:0060271 102 0.013
mitotic cytokinesis GO:0000281 4 0.013
peptidyl serine modification GO:0018209 83 0.013
nucleoside phosphate metabolic process GO:0006753 338 0.013
tube formation GO:0035148 140 0.013
organelle fission GO:0048285 170 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
calcium ion transmembrane transport GO:0070588 85 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
regulation of neuron projection development GO:0010975 169 0.013
protein maturation GO:0051604 176 0.013
neuron death GO:0070997 154 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
negative regulation of protein processing GO:0010955 79 0.013
negative regulation of mesenchymal cell proliferation involved in lung development GO:2000791 2 0.013
potassium ion transmembrane transport GO:0071805 43 0.013
regulation of macrophage migration inhibitory factor signaling pathway GO:2000446 1 0.013
maintenance of location GO:0051235 89 0.013
inter male aggressive behavior GO:0002121 3 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.013
negative regulation of cell cycle GO:0045786 123 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
negative regulation of ossification GO:0030279 49 0.013
synapse organization GO:0050808 125 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
translation GO:0006412 93 0.013
response to lipopolysaccharide GO:0032496 128 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
regulation of protein catabolic process GO:0042176 108 0.013
regulation of generation of precursor metabolites and energy GO:0043467 38 0.013
calcium ion homeostasis GO:0055074 127 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
mitotic cell cycle GO:0000278 195 0.012
nitrogen compound transport GO:0071705 271 0.012
cilium assembly GO:0042384 81 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
protein processing GO:0016485 163 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.012
nucleotide metabolic process GO:0009117 332 0.012
ossification GO:0001503 216 0.012
myelination GO:0042552 74 0.012
sodium ion transport GO:0006814 73 0.012
negative regulation of immune system process GO:0002683 209 0.012
negative regulation of vasculature development GO:1901343 26 0.012
cyclic nucleotide metabolic process GO:0009187 59 0.012
positive regulation of protein transport GO:0051222 93 0.012
negative regulation of hydrolase activity GO:0051346 71 0.012
fertilization GO:0009566 127 0.012
regulation of removal of superoxide radicals GO:2000121 4 0.012
regulation of map kinase activity GO:0043405 120 0.012
purine containing compound metabolic process GO:0072521 311 0.012
regulation of cellular response to stress GO:0080135 159 0.012
nucleoside metabolic process GO:0009116 246 0.012
second messenger mediated signaling GO:0019932 73 0.012
protein localization to nucleus GO:0034504 121 0.012
protein localization to organelle GO:0033365 185 0.012
positive regulation of cytoplasmic transport GO:1903651 40 0.012
response to glycoside GO:1903416 2 0.012
energy coupled proton transmembrane transport against electrochemical gradient GO:0015988 3 0.011
calcium ion transport GO:0006816 159 0.011
regulation of vasculature development GO:1901342 88 0.011
cell type specific apoptotic process GO:0097285 268 0.011
t cell activation GO:0042110 289 0.011
multicellular organismal signaling GO:0035637 91 0.011
cell growth GO:0016049 130 0.011
tissue remodeling GO:0048771 102 0.011
cellular protein complex assembly GO:0043623 116 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.011
ameboidal type cell migration GO:0001667 128 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
regulation of translation GO:0006417 71 0.011
regulation of protein binding GO:0043393 60 0.011
regulation of transferase activity GO:0051338 263 0.011
leukocyte migration GO:0050900 124 0.011
positive regulation of protein export from nucleus GO:0046827 4 0.011
meiotic cell cycle process GO:1903046 77 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
telencephalon development GO:0021537 186 0.011
protein import GO:0017038 101 0.011
cellular glucan metabolic process GO:0006073 32 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
response to hypoxia GO:0001666 58 0.011
exocytosis GO:0006887 121 0.011
regulation of transporter activity GO:0032409 57 0.011
regulation of protein maturation GO:1903317 96 0.011
negative regulation of dna replication GO:0008156 4 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.010
cytokine production GO:0001816 319 0.010
positive regulation of cell substrate adhesion GO:0010811 47 0.010
regulation of neuron differentiation GO:0045664 281 0.010
regulation of peptidyl serine phosphorylation GO:0033135 39 0.010
regulation of defense response GO:0031347 233 0.010
nucleoside monophosphate metabolic process GO:0009123 85 0.010
organelle localization GO:0051640 179 0.010
positive regulation of secretion by cell GO:1903532 114 0.010
meiotic nuclear division GO:0007126 115 0.010
regulation of protein processing GO:0070613 96 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
erk1 and erk2 cascade GO:0070371 77 0.010
membrane biogenesis GO:0044091 12 0.010
protein import into nucleus GO:0006606 95 0.010
establishment of protein localization to plasma membrane GO:0090002 34 0.010

Sspn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.374
musculoskeletal system disease DOID:17 0 0.374
muscle tissue disease DOID:66 0 0.374
myopathy DOID:423 0 0.374
muscular disease DOID:0080000 0 0.374
cardiomyopathy DOID:0050700 0 0.086
cardiovascular system disease DOID:1287 0 0.086
heart disease DOID:114 0 0.086
intrinsic cardiomyopathy DOID:0060036 0 0.086
muscular dystrophy DOID:9884 0 0.043
nervous system disease DOID:863 0 0.023
central nervous system disease DOID:331 0 0.020
dilated cardiomyopathy DOID:12930 0 0.015
brain disease DOID:936 0 0.015
immune system disease DOID:2914 0 0.012
vascular disease DOID:178 0 0.012
artery disease DOID:0050828 0 0.012
hematopoietic system disease DOID:74 0 0.010