Mus musculus

10 known processes

Cstb

cystatin B

(Aliases: Stfb,AA960480)

Cstb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sphingoid metabolic process GO:0046519 5 0.378
cation homeostasis GO:0055080 212 0.357
ion transmembrane transport GO:0034220 361 0.297
engulfment of apoptotic cell GO:0043652 3 0.247
cation transport GO:0006812 399 0.244
metal ion homeostasis GO:0055065 189 0.228
membrane organization GO:0061024 245 0.191
regulation of secretion GO:0051046 274 0.166
regulation of integrin biosynthetic process GO:0045113 1 0.161
cell chemotaxis GO:0060326 81 0.155
mature b cell differentiation involved in immune response GO:0002313 9 0.138
chemotaxis GO:0006935 247 0.137
vesicle organization GO:0016050 60 0.135
sphingosine metabolic process GO:0006670 4 0.133
actin cytoskeleton reorganization GO:0031532 21 0.112
lipid transport GO:0006869 98 0.110
sterol homeostasis GO:0055092 45 0.109
plasma cell differentiation GO:0002317 3 0.103
response to acid chemical GO:0001101 111 0.102
leukocyte chemotaxis GO:0030595 69 0.099
ceramide biosynthetic process GO:0046513 20 0.097
apoptotic signaling pathway GO:0097190 306 0.096
angiogenesis GO:0001525 201 0.094
integrin biosynthetic process GO:0045112 1 0.092
transmembrane transport GO:0055085 412 0.089
peptide transport GO:0015833 133 0.089
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.083
regulation of neuronal synaptic plasticity GO:0048168 30 0.079
endocytosis GO:0006897 168 0.077
regulation of binding GO:0051098 111 0.076
sphingolipid biosynthetic process GO:0030148 26 0.076
cellular divalent inorganic cation homeostasis GO:0072503 127 0.073
regulation of vesicle mediated transport GO:0060627 139 0.070
regulation of apoptotic signaling pathway GO:2001233 197 0.068
cellular chemical homeostasis GO:0055082 215 0.067
negative regulation of immunological synapse formation GO:2000521 1 0.067
cellular response to acid chemical GO:0071229 68 0.063
blood vessel morphogenesis GO:0048514 285 0.062
organelle membrane fusion GO:0090174 1 0.061
actin cytoskeleton organization GO:0030036 220 0.060
muscle cell development GO:0055001 133 0.059
positive regulation of mitochondrial calcium ion concentration GO:0051561 3 0.059
endomembrane system organization GO:0010256 147 0.059
synaptic transmission GO:0007268 329 0.058
cellular response to inorganic substance GO:0071241 37 0.057
cellular homeostasis GO:0019725 240 0.057
response to tumor necrosis factor GO:0034612 26 0.055
regulation of response to wounding GO:1903034 189 0.054
divalent metal ion transport GO:0070838 172 0.054
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.054
regulation of synaptic plasticity GO:0048167 87 0.053
positive regulation of neutrophil apoptotic process GO:0033031 1 0.053
regulation of immunological synapse formation GO:2000520 2 0.052
multi multicellular organism process GO:0044706 109 0.051
amide transport GO:0042886 138 0.049
positive regulation of cell death GO:0010942 224 0.047
divalent inorganic cation transport GO:0072511 178 0.047
organic anion transport GO:0015711 137 0.046
plasma membrane organization GO:0007009 90 0.045
nitrogen compound transport GO:0071705 271 0.045
negative regulation of t cell activation GO:0050868 65 0.044
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.044
t cell apoptotic process GO:0070231 39 0.043
negative regulation of lymphocyte activation GO:0051250 91 0.043
protein localization to membrane GO:0072657 108 0.043
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.042
regulation of membrane potential GO:0042391 192 0.041
regulation of neutrophil apoptotic process GO:0033029 1 0.040
response to inorganic substance GO:0010035 96 0.040
regulation of protein localization to nucleus GO:1900180 60 0.039
membrane lipid metabolic process GO:0006643 53 0.038
regulation of angiogenesis GO:0045765 81 0.038
molting cycle GO:0042303 90 0.038
leukocyte differentiation GO:0002521 342 0.038
sensory system development GO:0048880 3 0.037
leukocyte migration GO:0050900 124 0.037
positive regulation of organelle organization GO:0010638 128 0.037
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
skeletal system development GO:0001501 356 0.037
response to extracellular stimulus GO:0009991 127 0.036
actin polymerization or depolymerization GO:0008154 54 0.036
long chain fatty acid transport GO:0015909 15 0.036
muscle cell differentiation GO:0042692 261 0.036
organic acid transport GO:0015849 101 0.036
cellular protein complex assembly GO:0043623 116 0.036
sphingolipid metabolic process GO:0006665 45 0.035
striated muscle myosin thick filament assembly GO:0071688 1 0.035
cellular ion homeostasis GO:0006873 165 0.034
response to nutrient levels GO:0031667 109 0.034
actin filament organization GO:0007015 113 0.034
immune effector process GO:0002252 321 0.034
striated muscle tissue development GO:0014706 293 0.033
muscle tissue development GO:0060537 308 0.033
intracellular protein transport GO:0006886 204 0.033
neuromuscular process GO:0050905 99 0.033
regulation of ion transport GO:0043269 215 0.033
cognition GO:0050890 149 0.032
regulation of peptide transport GO:0090087 91 0.032
acetylcholine transport GO:0015870 2 0.032
sphingolipid catabolic process GO:0030149 7 0.032
organonitrogen compound catabolic process GO:1901565 264 0.032
positive regulation of binding GO:0051099 49 0.031
cholesterol homeostasis GO:0042632 44 0.031
water soluble vitamin biosynthetic process GO:0042364 3 0.030
extracellular matrix organization GO:0030198 147 0.030
ceramide metabolic process GO:0006672 31 0.029
morphogenesis of embryonic epithelium GO:0016331 159 0.029
cellular response to dna damage stimulus GO:0006974 207 0.029
regulation of mitotic cell cycle phase transition GO:1901990 73 0.029
cell growth GO:0016049 130 0.029
membrane lipid biosynthetic process GO:0046467 32 0.028
cellular ketone metabolic process GO:0042180 84 0.028
protein import GO:0017038 101 0.028
regulation of multi organism process GO:0043900 111 0.028
regulation of protein localization GO:0032880 231 0.027
peptide secretion GO:0002790 114 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
Human
regulation of actin filament based process GO:0032970 99 0.026
regulation of phospholipid biosynthetic process GO:0071071 3 0.026
negative regulation of intracellular transport GO:0032387 38 0.026
negative regulation of interleukin 8 secretion GO:2000483 1 0.026
regulation of t cell receptor signaling pathway GO:0050856 21 0.026
myeloid cell differentiation GO:0030099 233 0.026
lymphocyte differentiation GO:0030098 242 0.026
glycosylceramide catabolic process GO:0046477 2 0.026
regulation of homeostatic process GO:0032844 182 0.026
membrane fusion GO:0061025 38 0.026
oxidation reduction process GO:0055114 342 0.025
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.025
negative regulation of protein localization to nucleus GO:1900181 23 0.025
regulation of endocytosis GO:0030100 69 0.025
transition metal ion homeostasis GO:0055076 54 0.025
endothelial cell morphogenesis GO:0001886 9 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
protein localization to cell junction GO:1902414 3 0.025
positive regulation of homeostatic process GO:0032846 64 0.025
protein oligomerization GO:0051259 67 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
heterocycle catabolic process GO:0046700 280 0.024
nuclear import GO:0051170 95 0.024
myotube differentiation GO:0014902 105 0.024
developmental maturation GO:0021700 193 0.024
positive regulation of cellular component biogenesis GO:0044089 94 0.024
regulation of ion transmembrane transport GO:0034765 119 0.024
l ascorbic acid metabolic process GO:0019852 4 0.024
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.023
negative regulation of protein transport GO:0051224 46 0.023
monocyte chemotaxis GO:0002548 5 0.023
eosinophil migration GO:0072677 3 0.023
cellular response to lipid GO:0071396 145 0.023
positive regulation of vesicle fusion GO:0031340 2 0.023
organelle fusion GO:0048284 28 0.023
t cell receptor signaling pathway GO:0050852 46 0.023
exosomal secretion GO:1990182 1 0.023
monosaccharide metabolic process GO:0005996 106 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
regulation of ossification GO:0030278 112 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
muscle system process GO:0003012 141 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
tissue migration GO:0090130 68 0.022
diol metabolic process GO:0034311 5 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
regulation of wnt signaling pathway GO:0030111 123 0.022
neutrophil apoptotic process GO:0001781 3 0.022
regulation of protein import into nucleus GO:0042306 52 0.021
regulation of cellular component size GO:0032535 121 0.021
single organism cell adhesion GO:0098602 156 0.021
regulation of organelle organization GO:0033043 289 0.021
negative regulation of cytoplasmic transport GO:1903650 29 0.021
phagocytosis GO:0006909 66 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
skeletal muscle organ development GO:0060538 163 0.021
central nervous system morphogenesis GO:0021551 2 0.020
response to osmotic stress GO:0006970 21 0.020
interspecies interaction between organisms GO:0044419 83 0.020
homeostasis of number of cells GO:0048872 210 0.020
regulation of cytoskeleton organization GO:0051493 122 0.020
cell type specific apoptotic process GO:0097285 268 0.020
regulation of cell cycle GO:0051726 281 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
myosin filament organization GO:0031033 3 0.019
negative regulation of apoptotic signaling pathway GO:2001234 104 0.019
pentose metabolic process GO:0019321 5 0.019
viral process GO:0016032 41 0.019
muscle contraction GO:0006936 101 0.019
regulation of hydrolase activity GO:0051336 246 0.019
Human
positive regulation of protein modification process GO:0031401 299 0.019
ossification GO:0001503 216 0.019
carbohydrate catabolic process GO:0016052 32 0.019
male gamete generation GO:0048232 285 0.019
mitotic cell cycle GO:0000278 195 0.019
myoblast differentiation GO:0045445 52 0.019
inflammatory response GO:0006954 244 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
positive regulation of secretion GO:0051047 130 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
anion transport GO:0006820 177 0.018
chloride transmembrane transport GO:1902476 24 0.018
cell cell junction organization GO:0045216 72 0.018
amine metabolic process GO:0009308 45 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
i kappab kinase nf kappab signaling GO:0007249 85 0.018
organelle fission GO:0048285 170 0.018
mapk cascade GO:0000165 281 0.018
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
striated muscle cell development GO:0055002 125 0.017
t cell activation GO:0042110 289 0.017
signal transduction by p53 class mediator GO:0072331 51 0.017
regulation of interleukin 8 secretion GO:2000482 2 0.017
wnt signaling pathway GO:0016055 188 0.017
lymphocyte apoptotic process GO:0070227 54 0.017
positive regulation of wound healing GO:0090303 17 0.017
lateral line system development GO:0048925 1 0.017
stress response to metal ion GO:0097501 3 0.017
regulation of cellular amino acid metabolic process GO:0006521 5 0.017
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.017
protein autoprocessing GO:0016540 2 0.017
acetylcholine secretion neurotransmission GO:0014055 2 0.017
establishment of protein localization to organelle GO:0072594 118 0.017
alpha beta t cell differentiation GO:0046632 69 0.017
entry into host cell GO:0030260 15 0.016
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.016
small molecule biosynthetic process GO:0044283 132 0.016
positive regulation of cell cycle process GO:0090068 61 0.016
urogenital system development GO:0001655 261 0.016
b cell activation GO:0042113 161 0.016
response to molecule of bacterial origin GO:0002237 143 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 2 0.016
forebrain development GO:0030900 302 0.016
cellular amino acid metabolic process GO:0006520 103 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
g1 s transition of mitotic cell cycle GO:0000082 57 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
t cell differentiation GO:0030217 174 0.016
ameboidal type cell migration GO:0001667 128 0.016
cellular zinc ion homeostasis GO:0006882 9 0.016
protein localization to organelle GO:0033365 185 0.016
placenta development GO:0001890 140 0.016
development of primary sexual characteristics GO:0045137 143 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
autophagic vacuole fusion GO:0000046 1 0.015
cellular water homeostasis GO:0009992 2 0.015
limb development GO:0060173 166 0.015
negative regulation of endoplasmic reticulum calcium ion concentration GO:0032471 3 0.015
skin development GO:0043588 220 0.015
cell cell recognition GO:0009988 44 0.015
male gonad development GO:0008584 88 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
single organism nuclear import GO:1902593 95 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
calcium ion transport GO:0006816 159 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
positive regulation of ion transport GO:0043270 65 0.015
nucleoside phosphate metabolic process GO:0006753 338 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
positive regulation of necrotic cell death GO:0010940 1 0.015
lateral inhibition GO:0046331 1 0.015
b cell activation involved in immune response GO:0002312 50 0.015
regulation of peptide secretion GO:0002791 77 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
nucleotide metabolic process GO:0009117 332 0.014
regulation of transmembrane transport GO:0034762 128 0.014
negative regulation of cell activation GO:0050866 111 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
regulation of cell projection organization GO:0031344 206 0.014
cellular transition metal ion homeostasis GO:0046916 32 0.014
regulation of neuron differentiation GO:0045664 281 0.014
multi organism behavior GO:0051705 62 0.014
regulation of protein targeting GO:1903533 61 0.014
sterol transport GO:0015918 38 0.014
entry into host GO:0044409 15 0.014
protein import into nucleus GO:0006606 95 0.014
hair cycle GO:0042633 90 0.014
cell activation involved in immune response GO:0002263 126 0.014
regulation of protein transport GO:0051223 163 0.014
aromatic compound catabolic process GO:0019439 286 0.014
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.014
positive regulation of peptide secretion GO:0002793 33 0.014
wound healing GO:0042060 157 0.014
organic hydroxy compound transport GO:0015850 93 0.014
positive regulation of calcium ion transport GO:0051928 27 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
glucose homeostasis GO:0042593 128 0.014
lipid homeostasis GO:0055088 63 0.014
morphogenesis of a branching epithelium GO:0061138 193 0.014
learning or memory GO:0007611 148 0.014
telencephalon development GO:0021537 186 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
meiotic cell cycle GO:0051321 122 0.014
maintenance of location GO:0051235 89 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
ketone catabolic process GO:0042182 3 0.013
positive regulation of kinase activity GO:0033674 155 0.013
positive regulation of nervous system development GO:0051962 221 0.013
acetate ester transport GO:1901374 2 0.013
negative regulation of transcription factor import into nucleus GO:0042992 13 0.013
regulation of protein heterodimerization activity GO:0043497 2 0.013
negative regulation of neuron death GO:1901215 98 0.013
negative regulation of cytokine production GO:0001818 84 0.013
cell junction assembly GO:0034329 52 0.013
tumor necrosis factor mediated signaling pathway GO:0033209 13 0.013
regulation of cellular ketone metabolic process GO:0010565 66 0.013
myosin filament assembly GO:0031034 2 0.013
glycosylceramide metabolic process GO:0006677 4 0.013
negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:2001189 1 0.013
protein maturation GO:0051604 176 0.013
Human
regulation of neuron death GO:1901214 134 0.013
protein localization to plasma membrane GO:0072659 57 0.013
zinc ion homeostasis GO:0055069 10 0.013
response to monosaccharide GO:0034284 67 0.013
cellular response to tumor necrosis factor GO:0071356 21 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
calcium ion homeostasis GO:0055074 127 0.012
negative regulation of immune system process GO:0002683 209 0.012
organophosphate catabolic process GO:0046434 232 0.012
neuron death GO:0070997 154 0.012
interleukin 8 secretion GO:0072606 3 0.012
response to cadmium ion GO:0046686 8 0.012
rac protein signal transduction GO:0016601 13 0.012
apoptotic cell clearance GO:0043277 17 0.012
primitive erythrocyte differentiation GO:0060319 3 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
response to water GO:0009415 1 0.012
negative regulation of intracellular protein transport GO:0090317 27 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
mesonephros development GO:0001823 97 0.012
development of primary male sexual characteristics GO:0046546 88 0.012
regulation of interleukin 8 production GO:0032677 3 0.012
protein localization to nucleus GO:0034504 121 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
cell killing GO:0001906 67 0.012
fat cell differentiation GO:0045444 160 0.012
developmental cell growth GO:0048588 84 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
cellular response to antibiotic GO:0071236 4 0.012
interleukin 8 production GO:0032637 4 0.012
lymphocyte homeostasis GO:0002260 64 0.012
carbohydrate metabolic process GO:0005975 230 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
multicellular organismal signaling GO:0035637 91 0.012
response to organonitrogen compound GO:0010243 246 0.012
cholesterol efflux GO:0033344 24 0.012
lipid localization GO:0010876 126 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
cell proliferation in forebrain GO:0021846 30 0.012
positive regulation of response to wounding GO:1903036 66 0.012
hexose catabolic process GO:0019320 3 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
regulation of protein maturation GO:1903317 96 0.012
Human
epithelial cell proliferation GO:0050673 174 0.011
cytokine production GO:0001816 319 0.011
cellular amine metabolic process GO:0044106 44 0.011
negative regulation of cell cycle GO:0045786 123 0.011
sensory perception GO:0007600 245 0.011
epithelial cell morphogenesis GO:0003382 41 0.011
maintenance of apical basal cell polarity GO:0035090 3 0.011
cellular response to nutrient levels GO:0031669 64 0.011
t cell costimulation GO:0031295 14 0.011
regulation of kinase activity GO:0043549 249 0.011
regulation of intracellular transport GO:0032386 159 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
Human
galactose metabolic process GO:0006012 4 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
regulation of wound healing GO:0061041 40 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
regulation of ph GO:0006885 26 0.011
nuclear transport GO:0051169 139 0.011
leukocyte homeostasis GO:0001776 79 0.011
regulation of cellular ph GO:0030641 12 0.011
meiotic cell cycle process GO:1903046 77 0.011
epidermis development GO:0008544 187 0.011
determination of left right symmetry GO:0007368 80 0.011
cholesterol transport GO:0030301 38 0.011
hormone metabolic process GO:0042445 86 0.011
positive regulation of epithelial cell proliferation GO:0050679 68 0.011
regulation of anatomical structure size GO:0090066 178 0.011
positive regulation of cell development GO:0010720 237 0.011
positive regulation of leukocyte apoptotic process GO:2000108 21 0.011
forebrain radial glial cell differentiation GO:0021861 4 0.011
icosanoid secretion GO:0032309 12 0.011
cellular response to osmotic stress GO:0071470 7 0.011
circulatory system process GO:0003013 197 0.011
positive regulation of podosome assembly GO:0071803 3 0.011
regulation of cell substrate adhesion GO:0010810 73 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
negative regulation of ossification GO:0030279 49 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
immune response regulating signaling pathway GO:0002764 125 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
protein targeting GO:0006605 143 0.010
gonad development GO:0008406 141 0.010
nucleotide catabolic process GO:0009166 217 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
regulation of transcription factor import into nucleus GO:0042990 24 0.010
phagosome maturation GO:0090382 4 0.010
positive regulation of cell projection organization GO:0031346 95 0.010
neural tube development GO:0021915 160 0.010
notch signaling pathway GO:0007219 71 0.010
regulation of neuron projection development GO:0010975 169 0.010
regulation of nucleocytoplasmic transport GO:0046822 73 0.010
positive regulation of protein complex assembly GO:0031334 45 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010

Cstb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.259
inherited metabolic disorder DOID:655 0 0.259
disease of anatomical entity DOID:7 0 0.045
Human
nervous system disease DOID:863 0 0.045
Human
neuropathy DOID:870 0 0.045
neuromuscular disease DOID:440 0 0.037
charcot marie tooth disease DOID:10595 0 0.037
lipid storage disease DOID:9455 0 0.033
lysosomal storage disease DOID:3211 0 0.033
central nervous system disease DOID:331 0 0.022
Human
brain disease DOID:936 0 0.022
Human
sphingolipidosis DOID:1927 0 0.017
disease of mental health DOID:150 0 0.014
immune system disease DOID:2914 0 0.014
lymphatic system disease DOID:75 0 0.014