Mus musculus

29 known processes

Mcm7

minichromosome maintenance deficient 7 (S. cerevisiae)

(Aliases: AI747533,mCDC47,Mcmd7)

Mcm7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.996
dna dependent dna replication GO:0006261 24 0.996
recombinational repair GO:0000725 21 0.975
Yeast
cellular response to dna damage stimulus GO:0006974 207 0.973
Human Yeast Fly
aromatic compound catabolic process GO:0019439 286 0.944
Human Yeast
deoxyribonucleotide biosynthetic process GO:0009263 6 0.926
dna replication GO:0006260 52 0.912
dna geometric change GO:0032392 7 0.895
double strand break repair via homologous recombination GO:0000724 21 0.818
Yeast
meiotic cell cycle GO:0051321 122 0.802
mitotic cell cycle GO:0000278 195 0.779
Fly
nucleoside monophosphate metabolic process GO:0009123 85 0.744
Human Yeast
dna repair GO:0006281 107 0.736
Yeast
heterocycle catabolic process GO:0046700 280 0.731
Human Yeast
meiotic cell cycle process GO:1903046 77 0.667
cellular nitrogen compound catabolic process GO:0044270 280 0.655
Human Yeast
chromatin organization GO:0006325 206 0.646
gonad development GO:0008406 141 0.644
Worm
gene silencing GO:0016458 38 0.636
Yeast
organic cyclic compound catabolic process GO:1901361 295 0.622
Human Yeast
dna duplex unwinding GO:0032508 7 0.611
nuclear dna replication GO:0033260 3 0.549
Yeast
purine nucleoside catabolic process GO:0006152 205 0.516
Human Yeast
dna unwinding involved in dna replication GO:0006268 5 0.480
development of primary sexual characteristics GO:0045137 143 0.477
Worm
purine containing compound metabolic process GO:0072521 311 0.466
Human Yeast
double strand break repair GO:0006302 48 0.458
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 199 0.453
Human Yeast
dna conformation change GO:0071103 37 0.450
meiosis i GO:0007127 60 0.446
microtubule based process GO:0007017 236 0.442
organelle fission GO:0048285 170 0.435
regulation of cell cycle GO:0051726 281 0.417
Fly
dna recombination GO:0006310 92 0.412
Yeast
nucleobase containing small molecule metabolic process GO:0055086 352 0.409
Human Yeast
base excision repair GO:0006284 9 0.405
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.386
Human Yeast
ribonucleotide metabolic process GO:0009259 291 0.371
Human Yeast
chromosome segregation GO:0007059 48 0.353
ribonucleotide catabolic process GO:0009261 208 0.351
Human Yeast
organophosphate catabolic process GO:0046434 232 0.348
Human Yeast
microtubule cytoskeleton organization GO:0000226 157 0.331
nucleoside metabolic process GO:0009116 246 0.327
Human Yeast
purine nucleoside triphosphate catabolic process GO:0009146 203 0.313
Human Yeast
synapsis GO:0007129 34 0.300
protein dna complex subunit organization GO:0071824 28 0.296
Yeast
nucleotide metabolic process GO:0009117 332 0.289
Human Yeast
meiotic nuclear division GO:0007126 115 0.286
regulation of mitotic cell cycle phase transition GO:1901990 73 0.283
Fly
regulation of transcription by chromatin organization GO:0034401 0 0.283
purine ribonucleoside metabolic process GO:0046128 241 0.282
Human Yeast
purine ribonucleotide metabolic process GO:0009150 290 0.271
Human Yeast
purine nucleoside triphosphate metabolic process GO:0009144 226 0.270
Human Yeast
genitalia development GO:0048806 37 0.270
Worm
mitotic cell cycle process GO:1903047 159 0.265
Fly
chromatin silencing GO:0006342 15 0.252
Yeast
deoxyribonucleotide metabolic process GO:0009262 14 0.249
double strand break repair via nonhomologous end joining GO:0006303 10 0.249
negative regulation of nucleotide catabolic process GO:0030812 9 0.246
dna replication initiation GO:0006270 5 0.235
Yeast
negative regulation of gene expression epigenetic GO:0045814 15 0.234
Yeast
regulation of cellular catabolic process GO:0031329 242 0.212
ribonucleoside metabolic process GO:0009119 245 0.211
Human Yeast
rna dependent dna replication GO:0006278 3 0.209
negative regulation of mitotic cell cycle GO:0045930 58 0.207
Fly
nucleoside triphosphate catabolic process GO:0009143 205 0.198
Human Yeast
purine containing compound catabolic process GO:0072523 213 0.192
Human Yeast
ribose phosphate metabolic process GO:0019693 291 0.184
Human Yeast
mitotic spindle organization GO:0007052 10 0.184
purine nucleotide catabolic process GO:0006195 211 0.181
Human Yeast
ribonucleoside catabolic process GO:0042454 206 0.177
Human Yeast
nucleoside triphosphate metabolic process GO:0009141 230 0.175
Human Yeast
positive regulation of cell cycle phase transition GO:1901989 17 0.169
glycosyl compound metabolic process GO:1901657 246 0.165
Human Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.161
Human Yeast
dna integrity checkpoint GO:0031570 28 0.154
Fly
regulation of mitotic cell cycle GO:0007346 126 0.150
Fly
spindle organization GO:0007051 28 0.146
carbohydrate derivative catabolic process GO:1901136 231 0.145
Human Yeast
camera type eye development GO:0043010 266 0.145
nucleic acid transport GO:0050657 18 0.144
nucleoside phosphate catabolic process GO:1901292 222 0.144
Human Yeast
endocytosis GO:0006897 168 0.140
purine ribonucleoside catabolic process GO:0046130 205 0.139
Human Yeast
rna catabolic process GO:0006401 29 0.137
regulation of dna dependent dna replication initiation GO:0030174 3 0.132
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.130
Human Yeast
negative regulation of chromatin silencing GO:0031936 1 0.128
organonitrogen compound catabolic process GO:1901565 264 0.124
Human Yeast
reciprocal dna recombination GO:0035825 16 0.124
purine ribonucleotide catabolic process GO:0009154 208 0.123
Human Yeast
regulation of hydrolase activity GO:0051336 246 0.122
mitotic nuclear division GO:0007067 48 0.122
nucleoside phosphate metabolic process GO:0006753 338 0.115
Human Yeast
regulation of cell cycle process GO:0010564 160 0.113
Fly
purine nucleotide metabolic process GO:0006163 302 0.111
Human Yeast
atp catabolic process GO:0006200 55 0.110
Human Yeast
nucleotide catabolic process GO:0009166 217 0.109
Human Yeast
nucleotide biosynthetic process GO:0009165 78 0.106
regulation of dna dependent dna replication GO:0090329 8 0.103
nucleoside catabolic process GO:0009164 206 0.101
Human Yeast
ribonucleoside triphosphate metabolic process GO:0009199 220 0.100
Human Yeast
dna packaging GO:0006323 30 0.095
purine nucleoside metabolic process GO:0042278 241 0.093
Human Yeast
regulation of nucleotide catabolic process GO:0030811 122 0.092
cellular macromolecule catabolic process GO:0044265 206 0.088
chromatin modification GO:0016568 187 0.083
dna modification GO:0006304 50 0.082
spindle midzone assembly GO:0051255 1 0.079
g1 s transition of mitotic cell cycle GO:0000082 57 0.077
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.074
Human Yeast
purine nucleoside monophosphate catabolic process GO:0009128 58 0.074
Human Yeast
regulation of purine nucleotide catabolic process GO:0033121 122 0.073
ribonucleoside monophosphate catabolic process GO:0009158 57 0.071
Human Yeast
ribonucleoside monophosphate metabolic process GO:0009161 80 0.071
Human Yeast
negative regulation of atpase activity GO:0032780 2 0.066
dna catabolic process endonucleolytic GO:0000737 15 0.065
nucleobase containing compound transport GO:0015931 27 0.065
interspecies interaction between organisms GO:0044419 83 0.064
sister chromatid cohesion GO:0007062 12 0.064
negative regulation of nucleoside metabolic process GO:0045978 11 0.063
negative regulation of cell cycle GO:0045786 123 0.061
Fly
regulation of purine nucleotide metabolic process GO:1900542 169 0.061
small gtpase mediated signal transduction GO:0007264 97 0.060
protein modification by small protein conjugation GO:0032446 187 0.059
intracellular protein transport GO:0006886 204 0.059
macromolecule catabolic process GO:0009057 281 0.058
posttranscriptional regulation of gene expression GO:0010608 155 0.057
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.056
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.056
negative regulation of cellular protein metabolic process GO:0032269 247 0.056
nucleocytoplasmic transport GO:0006913 139 0.055
glycosyl compound catabolic process GO:1901658 206 0.055
Human Yeast
nuclear transport GO:0051169 139 0.054
cell cycle g1 s phase transition GO:0044843 57 0.053
positive regulation of cell cycle GO:0045787 92 0.053
receptor mediated endocytosis GO:0006898 51 0.052
telomere maintenance via telomerase GO:0007004 1 0.052
dendrite development GO:0016358 115 0.051
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.050
Fly
phagocytosis GO:0006909 66 0.050
cellular response to growth factor stimulus GO:0071363 197 0.049
cell division GO:0051301 120 0.048
chromosome organization involved in meiosis GO:0070192 39 0.048
germ cell development GO:0007281 185 0.048
reciprocal meiotic recombination GO:0007131 16 0.047
mitotic sister chromatid segregation GO:0000070 14 0.047
protein modification by small protein conjugation or removal GO:0070647 207 0.046
atp metabolic process GO:0046034 75 0.046
Human Yeast
regulation of nucleotide metabolic process GO:0006140 169 0.046
cell cycle checkpoint GO:0000075 47 0.046
Fly
regulation of ras protein signal transduction GO:0046578 114 0.045
inner cell mass cell proliferation GO:0001833 15 0.045
organophosphate biosynthetic process GO:0090407 122 0.045
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.045
gene silencing by rna GO:0031047 19 0.044
gtp catabolic process GO:0006184 143 0.044
protein localization to organelle GO:0033365 185 0.044
regulation of protein localization GO:0032880 231 0.043
positive regulation of protein modification process GO:0031401 299 0.043
regulation of nucleoside metabolic process GO:0009118 130 0.042
nucleoside monophosphate catabolic process GO:0009125 59 0.041
Human Yeast
regulation of intracellular protein transport GO:0033157 82 0.041
nucleotide excision repair GO:0006289 13 0.039
protein oligomerization GO:0051259 67 0.037
mitotic cell cycle checkpoint GO:0007093 31 0.037
Fly
viral process GO:0016032 41 0.037
regulation of nuclear cell cycle dna replication GO:0033262 2 0.037
protein import into nucleus GO:0006606 95 0.037
posttranscriptional gene silencing GO:0016441 10 0.036
nucleoside phosphate biosynthetic process GO:1901293 79 0.036
transcription coupled nucleotide excision repair GO:0006283 2 0.035
positive regulation of hydrolase activity GO:0051345 148 0.035
regulation of dna replication GO:0006275 17 0.034
purine nucleoside monophosphate metabolic process GO:0009126 81 0.033
Human Yeast
positive regulation of nucleotide metabolic process GO:0045981 114 0.033
positive regulation of intracellular transport GO:0032388 70 0.032
regulation of cytoplasmic transport GO:1903649 112 0.032
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.031
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.031
rna localization GO:0006403 23 0.030
axon guidance GO:0007411 141 0.030
protein ubiquitination GO:0016567 171 0.030
nuclear division GO:0000280 158 0.030
carbohydrate derivative biosynthetic process GO:1901137 183 0.030
positive regulation of nucleotide catabolic process GO:0030813 88 0.030
chemotaxis GO:0006935 247 0.030
regulation of organelle organization GO:0033043 289 0.029
regulation of dna damage checkpoint GO:2000001 3 0.029
protein maturation GO:0051604 176 0.029
sister chromatid segregation GO:0000819 20 0.029
gtp metabolic process GO:0046039 144 0.029
protein localization to chromatin GO:0071168 3 0.028
response to organic cyclic compound GO:0014070 198 0.028
intra s dna damage checkpoint GO:0031573 4 0.027
positive regulation of gtpase activity GO:0043547 85 0.027
regulation of cellular response to stress GO:0080135 159 0.027
metaphase plate congression GO:0051310 2 0.027
negative regulation of atp catabolic process GO:1903290 2 0.027
response to inorganic substance GO:0010035 96 0.027
cellular component disassembly involved in execution phase of apoptosis GO:0006921 9 0.027
translesion synthesis GO:0019985 1 0.027
blastocyst development GO:0001824 80 0.025
dna catabolic process GO:0006308 19 0.025
cellular response to cytokine stimulus GO:0071345 189 0.025
retina development in camera type eye GO:0060041 119 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.025
regulation of atp metabolic process GO:1903578 17 0.024
determination of adult lifespan GO:0008340 11 0.024
regulation of cellular component biogenesis GO:0044087 181 0.024
cytoplasmic transport GO:0016482 234 0.024
dna replication checkpoint GO:0000076 2 0.024
dna methylation GO:0006306 43 0.024
negative regulation of nucleotide metabolic process GO:0045980 16 0.024
apoptotic dna fragmentation GO:0006309 7 0.023
mitotic cytokinesis GO:0000281 4 0.023
activation of cdc42 gtpase activity GO:0032864 2 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
s adenosylhomocysteine metabolic process GO:0046498 1 0.023
nitrogen compound transport GO:0071705 271 0.023
protein targeting GO:0006605 143 0.022
methylation GO:0032259 134 0.022
ras protein signal transduction GO:0007265 77 0.022
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.022
viral life cycle GO:0019058 36 0.022
membrane organization GO:0061024 245 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
regulation of nucleocytoplasmic transport GO:0046822 73 0.022
histone modification GO:0016570 159 0.021
regulation of intracellular transport GO:0032386 159 0.021
protein localization to nucleus GO:0034504 121 0.021
sensory organ morphogenesis GO:0090596 242 0.021
regulation of cellular amino acid metabolic process GO:0006521 5 0.021
regulation of double strand break repair via nonhomologous end joining GO:2001032 2 0.021
protein import GO:0017038 101 0.021
positive regulation of protein transport GO:0051222 93 0.020
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.020
mitotic recombination GO:0006312 3 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
negative regulation of cell cycle process GO:0010948 69 0.020
Fly
response to oxidative stress GO:0006979 123 0.020
multicellular organismal aging GO:0010259 24 0.020
mrna processing GO:0006397 63 0.020
regulation of neuron death GO:1901214 134 0.019
covalent chromatin modification GO:0016569 163 0.019
cellular ketone metabolic process GO:0042180 84 0.019
non recombinational repair GO:0000726 10 0.019
apoptotic signaling pathway GO:0097190 306 0.019
stem cell differentiation GO:0048863 268 0.019
fertilization GO:0009566 127 0.019
pyrimidine containing compound metabolic process GO:0072527 11 0.019
guanosine containing compound metabolic process GO:1901068 144 0.018
amine metabolic process GO:0009308 45 0.018
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.018
mrna transport GO:0051028 13 0.018
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.018
protein processing GO:0016485 163 0.018
regulation of circadian sleep wake cycle GO:0042749 3 0.018
establishment of protein localization to organelle GO:0072594 118 0.018
positive regulation of histone modification GO:0031058 28 0.018
nuclear export GO:0051168 34 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
cellular amino acid metabolic process GO:0006520 103 0.017
mismatch repair GO:0006298 8 0.017
oxidation reduction process GO:0055114 342 0.017
macromolecule methylation GO:0043414 120 0.017
regulation of response to dna damage stimulus GO:2001020 34 0.017
negative regulation of gene silencing GO:0060969 2 0.017
dna topological change GO:0006265 2 0.017
regulation of vitamin d receptor signaling pathway GO:0070562 2 0.016
dna hypermethylation GO:0044026 3 0.016
multi multicellular organism process GO:0044706 109 0.016
protein heterotetramerization GO:0051290 4 0.016
telomere maintenance via telomere lengthening GO:0010833 4 0.016
synaptonemal complex organization GO:0070193 15 0.016
female gamete generation GO:0007292 74 0.016
locomotory behavior GO:0007626 195 0.016
multi organism behavior GO:0051705 62 0.016
mitotic centrosome separation GO:0007100 4 0.015
spermatogenesis GO:0007283 284 0.015
dna biosynthetic process GO:0071897 22 0.015
regulation of neuron projection development GO:0010975 169 0.015
spindle assembly involved in female meiosis GO:0007056 3 0.015
heterochromatin organization GO:0070828 4 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
leukocyte migration GO:0050900 124 0.014
anatomical structure homeostasis GO:0060249 145 0.014
regulation of cellular ketone metabolic process GO:0010565 66 0.014
negative regulation of histone h3 k9 methylation GO:0051573 4 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
regulation of cell division GO:0051302 76 0.014
synaptonemal complex assembly GO:0007130 13 0.014
cell type specific apoptotic process GO:0097285 268 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.014
cellular homeostasis GO:0019725 240 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
stem cell development GO:0048864 219 0.014
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902254 8 0.014
meiotic chromosome segregation GO:0045132 19 0.014
homeostasis of number of cells GO:0048872 210 0.013
mrna metabolic process GO:0016071 84 0.013
positive regulation of intracellular protein transport GO:0090316 42 0.013
rna transport GO:0050658 18 0.013
regulation of histone modification GO:0031056 56 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
chromatin remodeling GO:0006338 32 0.013
leukocyte proliferation GO:0070661 172 0.013
rna interference GO:0016246 2 0.013
molting cycle GO:0042303 90 0.013
regulation of microtubule cytoskeleton organization GO:0070507 37 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
positive regulation of transcription factor import into nucleus GO:0042993 8 0.013
cellular amine metabolic process GO:0044106 44 0.013
neurofilament cytoskeleton organization GO:0060052 10 0.013
regulation of meiotic cell cycle GO:0051445 34 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
histone phosphorylation GO:0016572 9 0.012
response to testosterone GO:0033574 3 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.012
skeletal system development GO:0001501 356 0.012
synaptic transmission GO:0007268 329 0.012
viral transcription GO:0019083 3 0.012
cytoplasmic mrna processing body assembly GO:0033962 6 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
response to lipopolysaccharide GO:0032496 128 0.012
establishment of rna localization GO:0051236 18 0.012
leukocyte apoptotic process GO:0071887 71 0.012
dna endoreduplication GO:0042023 4 0.012
nuclear import GO:0051170 95 0.012
response to cadmium ion GO:0046686 8 0.012
rna processing GO:0006396 105 0.012
response to acid chemical GO:0001101 111 0.012
body morphogenesis GO:0010171 45 0.012
Worm
regulation of neuron differentiation GO:0045664 281 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
positive regulation of fibroblast proliferation GO:0048146 20 0.011
positive regulation of meiotic cell cycle GO:0051446 15 0.011
neuron projection guidance GO:0097485 141 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
cellular response to interleukin 4 GO:0071353 21 0.011
generation of precursor metabolites and energy GO:0006091 103 0.011
response to oxygen levels GO:0070482 62 0.011
regulation of chromatin organization GO:1902275 57 0.011
regulation of chromosome organization GO:0033044 83 0.011
metal ion homeostasis GO:0055065 189 0.011
regulation of cell migration GO:0030334 219 0.011
protein localization to chromosome GO:0034502 6 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.010
cellular protein complex assembly GO:0043623 116 0.010
Worm
neural tube development GO:0021915 160 0.010
ossification GO:0001503 216 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.010
regulation of protein transport GO:0051223 163 0.010
organelle localization GO:0051640 179 0.010
establishment of organelle localization GO:0051656 122 0.010
neuron migration GO:0001764 122 0.010
learning or memory GO:0007611 148 0.010
response to hypoxia GO:0001666 58 0.010
negative regulation of hydrolase activity GO:0051346 71 0.010
engulfment of apoptotic cell GO:0043652 3 0.010

Mcm7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.104
gastrointestinal system cancer DOID:3119 0 0.060
cancer DOID:162 0 0.060
disease of cellular proliferation DOID:14566 0 0.060
organ system cancer DOID:0050686 0 0.060
inherited metabolic disorder DOID:655 0 0.042
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
large intestine cancer DOID:5672 0 0.014
intestinal cancer DOID:10155 0 0.014
central nervous system disease DOID:331 0 0.012