Mus musculus

0 known processes

Mcm5

minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)

(Aliases: AA617332,AI324988,Mcmd5,AL033333,P1-CDC46,mCD46,Cdc46,mCDC46)

Mcm5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna dependent dna replication GO:0006261 24 0.996
Yeast
dna metabolic process GO:0006259 303 0.984
Yeast Fly
dna geometric change GO:0032392 7 0.954
Yeast Fly
dna replication GO:0006260 52 0.945
Yeast Fly
double strand break repair via homologous recombination GO:0000724 21 0.944
Yeast
dna unwinding involved in dna replication GO:0006268 5 0.942
nuclear dna replication GO:0033260 3 0.934
Yeast
cellular response to dna damage stimulus GO:0006974 207 0.869
Yeast
protein dna complex subunit organization GO:0071824 28 0.735
Yeast
recombinational repair GO:0000725 21 0.720
Yeast
chromatin silencing GO:0006342 15 0.681
Yeast
dna replication initiation GO:0006270 5 0.673
Yeast
dna repair GO:0006281 107 0.665
Yeast
deoxyribonucleotide biosynthetic process GO:0009263 6 0.567
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.523
dna recombination GO:0006310 92 0.514
Yeast Fly
dna duplex unwinding GO:0032508 7 0.507
Yeast Fly
double strand break repair GO:0006302 48 0.502
Yeast
development of primary sexual characteristics GO:0045137 143 0.460
negative regulation of nucleoside metabolic process GO:0045978 11 0.422
sister chromatid cohesion GO:0007062 12 0.419
negative regulation of atp metabolic process GO:1903579 4 0.414
nucleoside phosphate catabolic process GO:1901292 222 0.404
Yeast
translesion synthesis GO:0019985 1 0.399
purine ribonucleotide metabolic process GO:0009150 290 0.340
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 199 0.325
Yeast
regulation of purine nucleotide catabolic process GO:0033121 122 0.319
atp catabolic process GO:0006200 55 0.313
Yeast
heterocycle catabolic process GO:0046700 280 0.313
Yeast
nucleobase containing small molecule metabolic process GO:0055086 352 0.293
Yeast
purine ribonucleoside catabolic process GO:0046130 205 0.267
Yeast
nucleotide catabolic process GO:0009166 217 0.265
Yeast
nucleoside triphosphate metabolic process GO:0009141 230 0.258
Yeast
purine ribonucleoside metabolic process GO:0046128 241 0.245
Yeast
regulation of cell cycle process GO:0010564 160 0.243
negative regulation of gene expression epigenetic GO:0045814 15 0.240
Yeast
nucleoside monophosphate metabolic process GO:0009123 85 0.240
Yeast
nucleotide metabolic process GO:0009117 332 0.227
Yeast
purine nucleoside catabolic process GO:0006152 205 0.225
Yeast
deoxyribonucleotide metabolic process GO:0009262 14 0.225
nucleoside phosphate metabolic process GO:0006753 338 0.221
Yeast
organophosphate catabolic process GO:0046434 232 0.216
Yeast
chromatin organization GO:0006325 206 0.212
Yeast
gene silencing GO:0016458 38 0.207
Yeast
purine nucleoside triphosphate metabolic process GO:0009144 226 0.207
Yeast
organic cyclic compound catabolic process GO:1901361 295 0.205
Yeast
regulation of cell cycle GO:0051726 281 0.198
gonad development GO:0008406 141 0.197
dna integrity checkpoint GO:0031570 28 0.191
endocytosis GO:0006897 168 0.189
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.176
Yeast
chromosome segregation GO:0007059 48 0.168
Fly
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.167
protein heterotetramerization GO:0051290 4 0.166
oxidation reduction process GO:0055114 342 0.165
regulation of cellular catabolic process GO:0031329 242 0.161
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.160
Yeast
negative regulation of cell cycle process GO:0010948 69 0.156
ribonucleoside catabolic process GO:0042454 206 0.155
Yeast
regulation of hydrolase activity GO:0051336 246 0.150
ribonucleotide catabolic process GO:0009261 208 0.145
Yeast
nucleoside catabolic process GO:0009164 206 0.144
Yeast
cell cycle g1 s phase transition GO:0044843 57 0.142
regulation of mitotic cell cycle phase transition GO:1901990 73 0.131
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.126
cellular nitrogen compound catabolic process GO:0044270 280 0.125
Yeast
negative regulation of atpase activity GO:0032780 2 0.124
genitalia development GO:0048806 37 0.123
aromatic compound catabolic process GO:0019439 286 0.119
Yeast
covalent chromatin modification GO:0016569 163 0.119
response to organic cyclic compound GO:0014070 198 0.114
purine containing compound catabolic process GO:0072523 213 0.113
Yeast
positive regulation of cell cycle GO:0045787 92 0.112
organism emergence from protective structure GO:0071684 4 0.111
microtubule based process GO:0007017 236 0.107
ribonucleotide metabolic process GO:0009259 291 0.106
Yeast
mitotic sister chromatid segregation GO:0000070 14 0.105
purine nucleotide catabolic process GO:0006195 211 0.105
Yeast
cellular response to interleukin 4 GO:0071353 21 0.104
microtubule cytoskeleton organization GO:0000226 157 0.103
nucleoside metabolic process GO:0009116 246 0.103
Yeast
purine nucleoside monophosphate catabolic process GO:0009128 58 0.101
Yeast
sister chromatid segregation GO:0000819 20 0.101
meiotic cell cycle process GO:1903046 77 0.100
Fly
purine containing compound metabolic process GO:0072521 311 0.098
Yeast
regulation of atp metabolic process GO:1903578 17 0.093
negative regulation of mitotic cell cycle GO:0045930 58 0.092
chromosome organization involved in meiosis GO:0070192 39 0.090
purine ribonucleotide catabolic process GO:0009154 208 0.086
Yeast
ribonucleoside monophosphate metabolic process GO:0009161 80 0.086
Yeast
purine nucleoside triphosphate catabolic process GO:0009146 203 0.085
Yeast
intrinsic apoptotic signaling pathway GO:0097193 132 0.083
ribose phosphate metabolic process GO:0019693 291 0.083
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.082
Yeast
meiotic cell cycle GO:0051321 122 0.082
Fly
purine nucleotide metabolic process GO:0006163 302 0.081
Yeast
mitotic cell cycle GO:0000278 195 0.080
Zebrafish
mitotic sister chromatid cohesion GO:0007064 1 0.079
cell cycle checkpoint GO:0000075 47 0.078
ribonucleoside metabolic process GO:0009119 245 0.073
Yeast
nuclear division GO:0000280 158 0.073
Fly
nucleoside monophosphate catabolic process GO:0009125 59 0.071
Yeast
organophosphate biosynthetic process GO:0090407 122 0.071
dna conformation change GO:0071103 37 0.070
Yeast Fly
negative regulation of cell cycle GO:0045786 123 0.069
regulation of nucleotide catabolic process GO:0030811 122 0.067
rna dependent dna replication GO:0006278 3 0.066
dna damage checkpoint GO:0000077 26 0.064
regulation of nuclear cell cycle dna replication GO:0033262 2 0.064
intra s dna damage checkpoint GO:0031573 4 0.064
nitrogen compound transport GO:0071705 271 0.063
cellular protein catabolic process GO:0044257 155 0.063
lateral inhibition GO:0046331 1 0.063
negative regulation of cell cycle phase transition GO:1901988 48 0.061
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.058
cellular response to cytokine stimulus GO:0071345 189 0.057
base excision repair GO:0006284 9 0.056
positive regulation of cellular catabolic process GO:0031331 148 0.056
purine nucleoside metabolic process GO:0042278 241 0.051
Yeast
ribonucleoside triphosphate metabolic process GO:0009199 220 0.051
Yeast
negative regulation of nucleotide catabolic process GO:0030812 9 0.051
receptor mediated endocytosis GO:0006898 51 0.050
meiotic nuclear division GO:0007126 115 0.050
Fly
regulation of mitotic cell cycle GO:0007346 126 0.049
cellular amino acid metabolic process GO:0006520 103 0.049
carbohydrate derivative catabolic process GO:1901136 231 0.048
Yeast
cofactor metabolic process GO:0051186 80 0.048
mitotic cell cycle process GO:1903047 159 0.047
organelle fission GO:0048285 170 0.047
Fly
nucleoside triphosphate catabolic process GO:0009143 205 0.047
Yeast
inner cell mass cell proliferation GO:0001833 15 0.047
protein modification by small protein conjugation or removal GO:0070647 207 0.045
synapsis GO:0007129 34 0.043
nucleoside phosphate biosynthetic process GO:1901293 79 0.041
double strand break repair via nonhomologous end joining GO:0006303 10 0.040
macromolecule catabolic process GO:0009057 281 0.040
dna endoreduplication GO:0042023 4 0.039
Fly
positive regulation of cell cycle phase transition GO:1901989 17 0.039
cellular homeostasis GO:0019725 240 0.039
apoptotic signaling pathway GO:0097190 306 0.038
regulation of cell cycle phase transition GO:1901987 77 0.038
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.038
Yeast
atp metabolic process GO:0046034 75 0.036
Yeast
rna catabolic process GO:0006401 29 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
dendrite development GO:0016358 115 0.036
glycosyl compound catabolic process GO:1901658 206 0.035
Yeast
regulation of atp catabolic process GO:1903289 9 0.035
response to testosterone GO:0033574 3 0.035
lipid homeostasis GO:0055088 63 0.034
cellular ketone metabolic process GO:0042180 84 0.034
regulation of nucleotide metabolic process GO:0006140 169 0.033
regulation of dna dependent dna replication GO:0090329 8 0.033
Yeast
organonitrogen compound catabolic process GO:1901565 264 0.032
Yeast
cellular macromolecule catabolic process GO:0044265 206 0.032
fatty acid homeostasis GO:0055089 5 0.031
mitotic nuclear division GO:0007067 48 0.031
chromatin assembly GO:0031497 13 0.031
membrane organization GO:0061024 245 0.031
response to purine containing compound GO:0014074 28 0.031
regulation of nucleoside metabolic process GO:0009118 130 0.030
regulation of cell division GO:0051302 76 0.030
peptidyl threonine phosphorylation GO:0018107 31 0.029
protein processing GO:0016485 163 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
g2 dna damage checkpoint GO:0031572 8 0.028
reciprocal dna recombination GO:0035825 16 0.028
Fly
asymmetric neuroblast division GO:0055059 1 0.028
iron sulfur cluster assembly GO:0016226 3 0.027
cell cell signaling involved in cell fate commitment GO:0045168 35 0.027
purine nucleoside monophosphate metabolic process GO:0009126 81 0.027
Yeast
g1 s transition of mitotic cell cycle GO:0000082 57 0.027
rhythmic process GO:0048511 174 0.027
amine metabolic process GO:0009308 45 0.026
negative regulation of hydrolase activity GO:0051346 71 0.026
response to light stimulus GO:0009416 135 0.026
response to organonitrogen compound GO:0010243 246 0.025
striated muscle myosin thick filament assembly GO:0071688 1 0.024
homeostasis of number of cells GO:0048872 210 0.024
regulation of cell motility GO:2000145 236 0.024
nucleotide biosynthetic process GO:0009165 78 0.024
epithelial tube morphogenesis GO:0060562 303 0.024
regulation of cell projection organization GO:0031344 206 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
spermatogenesis GO:0007283 284 0.023
response to inorganic substance GO:0010035 96 0.023
Zebrafish
folic acid containing compound metabolic process GO:0006760 3 0.023
mitotic g2 dna damage checkpoint GO:0007095 8 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
asymmetric stem cell division GO:0098722 3 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
regulation of cellular ketone metabolic process GO:0010565 66 0.022
spindle midzone assembly GO:0051255 1 0.022
protein oligomerization GO:0051259 67 0.022
circulatory system process GO:0003013 197 0.022
blood circulation GO:0008015 195 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.022
mitotic cell cycle checkpoint GO:0007093 31 0.022
female gamete generation GO:0007292 74 0.022
camera type eye development GO:0043010 266 0.022
Zebrafish
regulation of circadian sleep wake cycle GO:0042749 3 0.022
protein ubiquitination GO:0016567 171 0.022
cyclin catabolic process GO:0008054 1 0.021
histone monoubiquitination GO:0010390 3 0.021
blastocyst development GO:0001824 80 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
Yeast
cell type specific apoptotic process GO:0097285 268 0.021
chromatin modification GO:0016568 187 0.020
Yeast
response to vitamin a GO:0033189 1 0.020
negative regulation of nucleotide metabolic process GO:0045980 16 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
glial cell differentiation GO:0010001 131 0.020
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.019
regulation of organelle organization GO:0033043 289 0.019
mitotic chromosome condensation GO:0007076 1 0.019
positive regulation of cell death GO:0010942 224 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.019
positive regulation of atpase activity GO:0032781 3 0.019
cellular amine metabolic process GO:0044106 44 0.019
regulation of dna dependent dna replication initiation GO:0030174 3 0.019
Yeast
reciprocal meiotic recombination GO:0007131 16 0.019
Fly
regulation of ran gtpase activity GO:0032316 3 0.018
signal transduction by p53 class mediator GO:0072331 51 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
mitotic sister chromatid separation GO:0051306 9 0.018
regulation of secretion GO:0051046 274 0.018
ubiquitin dependent protein catabolic process GO:0006511 129 0.018
peptidyl amino acid modification GO:0018193 336 0.018
response to oxidative stress GO:0006979 123 0.018
hatching GO:0035188 4 0.018
response to metal ion GO:0010038 47 0.018
Zebrafish
ribonucleoside monophosphate catabolic process GO:0009158 57 0.017
Yeast
protein localization to chromatin GO:0071168 3 0.017
cell adhesion GO:0007155 329 0.017
cleavage furrow formation GO:0036089 2 0.017
mitotic centrosome separation GO:0007100 4 0.017
notch signaling pathway GO:0007219 71 0.017
negative regulation of cell development GO:0010721 169 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
regulation of secretion by cell GO:1903530 249 0.017
telomere maintenance via telomerase GO:0007004 1 0.016
s adenosylhomocysteine metabolic process GO:0046498 1 0.016
morphogenesis of a branching epithelium GO:0061138 193 0.016
negative regulation of cell division GO:0051782 24 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
response to interleukin 4 GO:0070670 23 0.016
germ cell development GO:0007281 185 0.016
regulation of neuron differentiation GO:0045664 281 0.016
protein maturation GO:0051604 176 0.016
glucose homeostasis GO:0042593 128 0.016
engulfment of apoptotic cell GO:0043652 3 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
dna ligation GO:0006266 3 0.016
histone modification GO:0016570 159 0.016
non recombinational repair GO:0000726 10 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
cell division GO:0051301 120 0.015
protein heterooligomerization GO:0051291 14 0.015
response to radiation GO:0009314 165 0.015
gtp catabolic process GO:0006184 143 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
regulation of double strand break repair via homologous recombination GO:0010569 2 0.015
positive regulation of protein modification process GO:0031401 299 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
positive regulation of chromosome segregation GO:0051984 4 0.015
regulation of cellular response to stress GO:0080135 159 0.014
placenta development GO:0001890 140 0.014
protein catabolic process GO:0030163 221 0.014
protein homooligomerization GO:0051260 43 0.014
body morphogenesis GO:0010171 45 0.014
regulation of synaptic plasticity GO:0048167 87 0.014
regulation of leukocyte apoptotic process GO:2000106 56 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
negative regulation of atp catabolic process GO:1903290 2 0.014
neural tube development GO:0021915 160 0.013
coenzyme metabolic process GO:0006732 52 0.013
response to acid chemical GO:0001101 111 0.013
striated muscle cell development GO:0055002 125 0.013
regulation of inflammatory response GO:0050727 147 0.013
cellular chemical homeostasis GO:0055082 215 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
regulation of defense response GO:0031347 233 0.013
protein localization to organelle GO:0033365 185 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
regulation of cell migration GO:0030334 219 0.013
protein localization to chromosome GO:0034502 6 0.013
dna replication independent nucleosome assembly GO:0006336 1 0.013
locomotory behavior GO:0007626 195 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
branching morphogenesis of an epithelial tube GO:0048754 159 0.013
ras protein signal transduction GO:0007265 77 0.012
histone phosphorylation GO:0016572 9 0.012
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 1 0.012
negative regulation of molecular function GO:0044092 258 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
cellular response to radiation GO:0071478 28 0.012
peptide transport GO:0015833 133 0.012
connective tissue development GO:0061448 179 0.012
maintenance of dna methylation GO:0010216 4 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
skeletal system development GO:0001501 356 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
anatomical structure homeostasis GO:0060249 145 0.012
sulfur compound metabolic process GO:0006790 100 0.012
dna replication checkpoint GO:0000076 2 0.012
stem cell proliferation GO:0072089 117 0.012
cell fate commitment GO:0045165 210 0.012
positive regulation of nuclear division GO:0051785 27 0.012
regulation of histone modification GO:0031056 56 0.011
mitochondrion organization GO:0007005 134 0.011
myeloid cell differentiation GO:0030099 233 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
intracellular mrna localization GO:0008298 4 0.011
regulation of atpase activity GO:0043462 9 0.011
cation transport GO:0006812 399 0.011
peptidyl serine phosphorylation GO:0018105 74 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
positive regulation of organelle organization GO:0010638 128 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
leukocyte proliferation GO:0070661 172 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
positive regulation of gtpase activity GO:0043547 85 0.011
negative regulation of organelle organization GO:0010639 90 0.011
amide transport GO:0042886 138 0.011
gtp metabolic process GO:0046039 144 0.010
alpha amino acid metabolic process GO:1901605 59 0.010
sensory perception GO:0007600 245 0.010
positive regulation of attachment of spindle microtubules to kinetochore GO:0051987 2 0.010
generation of precursor metabolites and energy GO:0006091 103 0.010
neuron death GO:0070997 154 0.010

Mcm5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.332
cancer DOID:162 0 0.280
gastrointestinal system cancer DOID:3119 0 0.221
organ system cancer DOID:0050686 0 0.221
disease of metabolism DOID:0014667 0 0.209
inherited metabolic disorder DOID:655 0 0.209
intestinal cancer DOID:10155 0 0.085
large intestine cancer DOID:5672 0 0.062
carbohydrate metabolic disorder DOID:2978 0 0.022
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
peripheral neuropathy DOID:0060053 0 0.016
neuropathy DOID:870 0 0.016
thoracic cancer DOID:5093 0 0.015
hereditary sensory neuropathy DOID:0050548 0 0.013
breast cancer DOID:1612 0 0.012
colorectal cancer DOID:9256 0 0.010