Mus musculus

27 known processes

Mcm4

minichromosome maintenance deficient 4 homolog (S. cerevisiae)

(Aliases: Mcmd4,mKIAA4003,AU045576,AI325074,Cdc21,KIAA4003,19G,mcdc21)

Mcm4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.999
dna replication GO:0006260 52 0.989
dna dependent dna replication GO:0006261 24 0.974
dna repair GO:0006281 107 0.965
Yeast
meiotic cell cycle process GO:1903046 77 0.958
cellular response to dna damage stimulus GO:0006974 207 0.958
Yeast
recombinational repair GO:0000725 21 0.956
Yeast
meiotic cell cycle GO:0051321 122 0.955
nuclear dna replication GO:0033260 3 0.874
Yeast
mitotic cell cycle process GO:1903047 159 0.814
Fly
meiosis i GO:0007127 60 0.782
development of primary sexual characteristics GO:0045137 143 0.775
organelle fission GO:0048285 170 0.745
gonad development GO:0008406 141 0.726
meiotic nuclear division GO:0007126 115 0.668
intrinsic apoptotic signaling pathway GO:0097193 132 0.654
gene silencing GO:0016458 38 0.642
dna modification GO:0006304 50 0.590
base excision repair GO:0006284 9 0.589
chromosome segregation GO:0007059 48 0.586
dna conformation change GO:0071103 37 0.582
dna packaging GO:0006323 30 0.577
double strand break repair GO:0006302 48 0.567
Yeast
negative regulation of gene expression epigenetic GO:0045814 15 0.565
dna replication initiation GO:0006270 5 0.558
Yeast
mitotic cell cycle GO:0000278 195 0.522
Fly
chromatin organization GO:0006325 206 0.519
dna recombination GO:0006310 92 0.518
Yeast
negative regulation of mitotic cell cycle GO:0045930 58 0.497
deoxyribonucleotide metabolic process GO:0009262 14 0.485
apoptotic signaling pathway GO:0097190 306 0.485
protein dna complex subunit organization GO:0071824 28 0.469
Yeast
positive regulation of hydrolase activity GO:0051345 148 0.469
cell cycle checkpoint GO:0000075 47 0.453
nucleobase containing small molecule metabolic process GO:0055086 352 0.451
Human Yeast
deoxyribonucleotide biosynthetic process GO:0009263 6 0.449
regulation of dna replication GO:0006275 17 0.405
double strand break repair via homologous recombination GO:0000724 21 0.394
Yeast
chromosome organization involved in meiosis GO:0070192 39 0.386
heterochromatin organization GO:0070828 4 0.369
camera type eye development GO:0043010 266 0.338
dna hypermethylation GO:0044026 3 0.337
reciprocal dna recombination GO:0035825 16 0.322
nucleoside phosphate metabolic process GO:0006753 338 0.322
Human Yeast
genitalia development GO:0048806 37 0.319
nuclear division GO:0000280 158 0.315
regulation of apoptotic signaling pathway GO:2001233 197 0.310
meiotic chromosome segregation GO:0045132 19 0.309
amine metabolic process GO:0009308 45 0.297
regulation of transcription by chromatin organization GO:0034401 0 0.297
regulation of hydrolase activity GO:0051336 246 0.294
rna dependent dna replication GO:0006278 3 0.291
double strand break repair via nonhomologous end joining GO:0006303 10 0.275
response to organic cyclic compound GO:0014070 198 0.274
cellular macromolecule catabolic process GO:0044265 206 0.250
nitrogen compound transport GO:0071705 271 0.250
chromatin remodeling at centromere GO:0031055 2 0.244
negative regulation of cell cycle GO:0045786 123 0.232
cellular response to radiation GO:0071478 28 0.231
response to ionizing radiation GO:0010212 42 0.229
mrna transport GO:0051028 13 0.215
nuclear transport GO:0051169 139 0.199
methylation GO:0032259 134 0.193
negative regulation of chromatin silencing GO:0031936 1 0.189
response to metal ion GO:0010038 47 0.183
dna methylation GO:0006306 43 0.182
regulation of cell cycle process GO:0010564 160 0.179
glycosyl compound metabolic process GO:1901657 246 0.178
Human Yeast
oxidation reduction process GO:0055114 342 0.177
dna geometric change GO:0032392 7 0.175
regulation of cell cycle phase transition GO:1901987 77 0.173
heterocycle catabolic process GO:0046700 280 0.172
Human Yeast
endocytosis GO:0006897 168 0.172
Worm
cellular ketone metabolic process GO:0042180 84 0.171
reciprocal meiotic recombination GO:0007131 16 0.170
protein ubiquitination GO:0016567 171 0.168
cellular amino acid metabolic process GO:0006520 103 0.166
dna endoreduplication GO:0042023 4 0.162
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.158
chromatin silencing GO:0006342 15 0.154
organophosphate biosynthetic process GO:0090407 122 0.153
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.150
regulation of cell cycle GO:0051726 281 0.149
regulation of mitotic cell cycle GO:0007346 126 0.147
oogenesis GO:0048477 56 0.147
nucleocytoplasmic transport GO:0006913 139 0.142
receptor mediated endocytosis GO:0006898 51 0.142
positive regulation of meiotic cell cycle GO:0051446 15 0.139
aromatic compound catabolic process GO:0019439 286 0.139
Human Yeast
regulation of cellular amino acid metabolic process GO:0006521 5 0.137
rna transport GO:0050658 18 0.135
nucleoside metabolic process GO:0009116 246 0.135
Human Yeast
cellular nitrogen compound catabolic process GO:0044270 280 0.133
Human Yeast
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.131
chromatin modification GO:0016568 187 0.130
gene silencing by rna GO:0031047 19 0.129
cell fate commitment GO:0045165 210 0.127
nucleoside phosphate biosynthetic process GO:1901293 79 0.126
ribonucleoside triphosphate metabolic process GO:0009199 220 0.126
Human Yeast
intra s dna damage checkpoint GO:0031573 4 0.122
response to oxidative stress GO:0006979 123 0.119
chromatin assembly or disassembly GO:0006333 16 0.119
regulation of histone methylation GO:0031060 30 0.118
chromatin assembly GO:0031497 13 0.110
cellular amine metabolic process GO:0044106 44 0.108
pyrimidine containing compound metabolic process GO:0072527 11 0.108
dna alkylation GO:0006305 43 0.108
histone acetylation GO:0016573 41 0.107
protein targeting GO:0006605 143 0.107
positive regulation of programmed cell death GO:0043068 218 0.106
response to purine containing compound GO:0014074 28 0.104
regulation of chromosome organization GO:0033044 83 0.104
wnt signaling pathway GO:0016055 188 0.104
peptidyl amino acid modification GO:0018193 336 0.103
response to molecule of bacterial origin GO:0002237 143 0.102
cellular response to cytokine stimulus GO:0071345 189 0.102
spermatogenesis GO:0007283 284 0.102
purine ribonucleotide catabolic process GO:0009154 208 0.101
Human Yeast
regulation of purine nucleotide metabolic process GO:1900542 169 0.101
mitotic sister chromatid segregation GO:0000070 14 0.100
purine nucleoside triphosphate metabolic process GO:0009144 226 0.099
Human Yeast
regulation of cellular catabolic process GO:0031329 242 0.099
ribonucleoside metabolic process GO:0009119 245 0.097
Human Yeast
cell cycle g1 s phase transition GO:0044843 57 0.096
nucleoside triphosphate metabolic process GO:0009141 230 0.096
Human Yeast
response to inorganic substance GO:0010035 96 0.096
posttranscriptional regulation of gene expression GO:0010608 155 0.096
cell type specific apoptotic process GO:0097285 268 0.095
protein modification by small protein conjugation or removal GO:0070647 207 0.094
ras protein signal transduction GO:0007265 77 0.092
positive regulation of gtp catabolic process GO:0033126 85 0.092
single organism nuclear import GO:1902593 95 0.092
regulation of peptidase activity GO:0052547 96 0.091
regulation of cellular ketone metabolic process GO:0010565 66 0.089
regulation of kinase activity GO:0043549 249 0.089
dna damage checkpoint GO:0000077 26 0.087
maintenance of dna methylation GO:0010216 4 0.087
cellular response to growth factor stimulus GO:0071363 197 0.086
regulation of chromatin modification GO:1903308 57 0.084
generation of precursor metabolites and energy GO:0006091 103 0.084
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.083
embryonic organ morphogenesis GO:0048562 276 0.083
response to uv GO:0009411 44 0.081
ribonucleotide metabolic process GO:0009259 291 0.081
Human Yeast
protein localization to organelle GO:0033365 185 0.081
positive regulation of cellular amine metabolic process GO:0033240 5 0.081
maintenance of cell number GO:0098727 3 0.081
regulation of transferase activity GO:0051338 263 0.080
covalent chromatin modification GO:0016569 163 0.079
negative regulation of molecular function GO:0044092 258 0.078
ribonucleotide catabolic process GO:0009261 208 0.076
Human Yeast
rna 3 end processing GO:0031123 20 0.076
ribonucleoside triphosphate catabolic process GO:0009203 199 0.076
Human Yeast
negative regulation of cell cycle phase transition GO:1901988 48 0.075
response to steroid hormone GO:0048545 56 0.074
response to alkaloid GO:0043279 34 0.074
positive regulation of cellular catabolic process GO:0031331 148 0.074
rna interference GO:0016246 2 0.074
histone lysine methylation GO:0034968 50 0.074
sensory organ morphogenesis GO:0090596 242 0.074
mitotic recombination GO:0006312 3 0.074
purine ribonucleoside metabolic process GO:0046128 241 0.073
Human Yeast
ribose phosphate metabolic process GO:0019693 291 0.073
Human Yeast
protein heterotetramerization GO:0051290 4 0.072
negative regulation of cellular component organization GO:0051129 194 0.072
microtubule cytoskeleton organization GO:0000226 157 0.072
Fly
nucleobase containing compound transport GO:0015931 27 0.072
digestive system development GO:0055123 200 0.072
response to vitamin a GO:0033189 1 0.071
positive regulation of cell death GO:0010942 224 0.071
germ cell development GO:0007281 185 0.070
nucleoside catabolic process GO:0009164 206 0.070
Human Yeast
intracellular protein transport GO:0006886 204 0.069
ameboidal type cell migration GO:0001667 128 0.069
male gamete generation GO:0048232 285 0.069
non recombinational repair GO:0000726 10 0.068
i kappab kinase nf kappab signaling GO:0007249 85 0.068
regulation of chromatin organization GO:1902275 57 0.068
protein import into nucleus GO:0006606 95 0.068
positive regulation of apoptotic process GO:0043065 217 0.068
response to radiation GO:0009314 165 0.067
purine nucleotide catabolic process GO:0006195 211 0.067
Human Yeast
positive regulation of cell cycle GO:0045787 92 0.066
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.065
phagocytosis GO:0006909 66 0.065
Worm
regulation of protein kinase activity GO:0045859 232 0.065
regulation of intracellular protein transport GO:0033157 82 0.064
dendrite development GO:0016358 115 0.064
digestive tract development GO:0048565 190 0.063
digestive tract morphogenesis GO:0048546 147 0.063
synaptonemal complex assembly GO:0007130 13 0.062
nucleotide metabolic process GO:0009117 332 0.062
Human Yeast
purine nucleoside metabolic process GO:0042278 241 0.062
Human Yeast
sister chromatid segregation GO:0000819 20 0.061
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.059
Human Yeast
nucleotide biosynthetic process GO:0009165 78 0.059
small gtpase mediated signal transduction GO:0007264 97 0.059
rna localization GO:0006403 23 0.059
response to caffeine GO:0031000 6 0.059
ventricular system development GO:0021591 27 0.059
actin cytoskeleton organization GO:0030036 220 0.058
glial cell differentiation GO:0010001 131 0.058
nucleic acid transport GO:0050657 18 0.058
dna unwinding involved in dna replication GO:0006268 5 0.058
regulation of mitotic cell cycle phase transition GO:1901990 73 0.057
histone modification GO:0016570 159 0.056
posttranscriptional gene silencing GO:0016441 10 0.056
purine nucleoside triphosphate catabolic process GO:0009146 203 0.055
Human Yeast
negative regulation of cell cycle process GO:0010948 69 0.055
regulation of nucleotide catabolic process GO:0030811 122 0.052
regulation of cytoplasmic transport GO:1903649 112 0.051
cytoplasmic transport GO:0016482 234 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
purine nucleotide metabolic process GO:0006163 302 0.050
Human Yeast
mitotic nuclear division GO:0007067 48 0.049
cellular response to organonitrogen compound GO:0071417 145 0.049
response to lipopolysaccharide GO:0032496 128 0.048
purine ribonucleotide metabolic process GO:0009150 290 0.048
Human Yeast
pore complex assembly GO:0046931 3 0.048
regulation of cellular response to stress GO:0080135 159 0.048
response to organonitrogen compound GO:0010243 246 0.048
retina development in camera type eye GO:0060041 119 0.048
cofactor metabolic process GO:0051186 80 0.047
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.047
Human Yeast
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.047
synapsis GO:0007129 34 0.047
multicellular organism growth GO:0035264 161 0.047
b cell activation GO:0042113 161 0.046
negative regulation of cellular protein metabolic process GO:0032269 247 0.046
neuron death GO:0070997 154 0.046
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.046
positive regulation of cell cycle phase transition GO:1901989 17 0.046
dna ligation GO:0006266 3 0.045
regulation of purine nucleotide catabolic process GO:0033121 122 0.045
dna integrity checkpoint GO:0031570 28 0.045
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.045
epithelial tube morphogenesis GO:0060562 303 0.044
regulation of nuclear division GO:0051783 56 0.044
response to growth factor GO:0070848 198 0.044
regulation of cellular amine metabolic process GO:0033238 20 0.043
chemotaxis GO:0006935 247 0.043
dna biosynthetic process GO:0071897 22 0.042
response to extracellular stimulus GO:0009991 127 0.041
tricarboxylic acid metabolic process GO:0072350 5 0.041
cellular response to oxidative stress GO:0034599 76 0.041
regulation of histone modification GO:0031056 56 0.041
female gamete generation GO:0007292 74 0.041
regulation of nucleotide metabolic process GO:0006140 169 0.041
ribonucleoside catabolic process GO:0042454 206 0.040
Human Yeast
purine nucleoside catabolic process GO:0006152 205 0.040
Human Yeast
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.040
meiotic chromosome condensation GO:0010032 3 0.040
extrinsic apoptotic signaling pathway GO:0097191 126 0.040
protein localization to nucleus GO:0034504 121 0.040
telomere maintenance via telomerase GO:0007004 1 0.039
morphogenesis of embryonic epithelium GO:0016331 159 0.039
response to glucocorticoid GO:0051384 20 0.039
circadian rhythm GO:0007623 114 0.039
regulation of protein import into nucleus GO:0042306 52 0.039
nucleoside phosphate catabolic process GO:1901292 222 0.039
Human Yeast
macromolecule methylation GO:0043414 120 0.039
intraspecies interaction between organisms GO:0051703 21 0.039
neuroblast fate determination GO:0007400 1 0.039
regulation of double strand break repair via homologous recombination GO:0010569 2 0.039
negative regulation of histone h3 k9 methylation GO:0051573 4 0.039
ovulation GO:0030728 15 0.038
cell migration involved in gastrulation GO:0042074 13 0.038
nucleotide excision repair GO:0006289 13 0.038
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.038
stem cell development GO:0048864 219 0.038
regulation of actin filament based process GO:0032970 99 0.037
membrane organization GO:0061024 245 0.037
Worm
mitotic cell cycle checkpoint GO:0007093 31 0.036
dna templated transcription termination GO:0006353 4 0.036
response to light stimulus GO:0009416 135 0.036
dna catabolic process GO:0006308 19 0.036
mrna processing GO:0006397 63 0.036
mitotic g2 dna damage checkpoint GO:0007095 8 0.035
gliogenesis GO:0042063 141 0.035
protein maturation GO:0051604 176 0.035
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.035
nucleus organization GO:0006997 45 0.035
Worm
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 11 0.034
cellular amide metabolic process GO:0043603 58 0.034
positive regulation of meiosis i GO:0060903 5 0.034
regulation of protein localization to nucleus GO:1900180 60 0.034
regulation of nucleoside metabolic process GO:0009118 130 0.033
response to heat GO:0009408 27 0.033
cellular response to inorganic substance GO:0071241 37 0.033
internal peptidyl lysine acetylation GO:0018393 42 0.033
macromolecule catabolic process GO:0009057 281 0.033
positive regulation of histone h3 k4 methylation GO:0051571 5 0.032
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.032
posttranscriptional gene silencing by rna GO:0035194 10 0.032
organic cyclic compound catabolic process GO:1901361 295 0.032
Human Yeast
rna catabolic process GO:0006401 29 0.032
regulation of circadian rhythm GO:0042752 58 0.031
axonogenesis GO:0007409 274 0.031
regulation of cell division GO:0051302 76 0.031
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.031
lamellipodium organization GO:0097581 29 0.031
response to testosterone GO:0033574 3 0.031
regulation of neuron apoptotic process GO:0043523 122 0.030
purine nucleoside monophosphate metabolic process GO:0009126 81 0.030
Human Yeast
s adenosylhomocysteine metabolic process GO:0046498 1 0.030
positive regulation of gtpase activity GO:0043547 85 0.030
cell fate determination GO:0001709 32 0.030
regulation of cell cycle g1 s phase transition GO:1902806 35 0.030
regulation of systemic arterial blood pressure by vasopressin GO:0001992 3 0.030
positive regulation of proteolysis GO:0045862 85 0.029
peptidyl tyrosine phosphorylation GO:0018108 143 0.029
purine containing compound metabolic process GO:0072521 311 0.029
Human Yeast
organophosphate catabolic process GO:0046434 232 0.028
Human Yeast
purine containing compound catabolic process GO:0072523 213 0.028
Human Yeast
regulation of organelle organization GO:0033043 289 0.028
hematopoietic progenitor cell differentiation GO:0002244 143 0.028
maintenance of protein location in nucleus GO:0051457 2 0.028
regulation of neuron death GO:1901214 134 0.028
neuron apoptotic process GO:0051402 142 0.028
regulation of nucleocytoplasmic transport GO:0046822 73 0.028
gastrulation GO:0007369 116 0.028
positive regulation of nucleotide metabolic process GO:0045981 114 0.028
positive regulation of intracellular transport GO:0032388 70 0.027
regulation of protein transport GO:0051223 163 0.027
negative regulation of gene silencing GO:0060969 2 0.027
regulation of response to dna damage stimulus GO:2001020 34 0.027
negative regulation of chromosome organization GO:2001251 30 0.027
regulation of muscle system process GO:0090257 80 0.027
rhythmic process GO:0048511 174 0.026
positive regulation of protein phosphorylation GO:0001934 242 0.026
glycosyl compound catabolic process GO:1901658 206 0.026
Human Yeast
negative regulation of apoptotic signaling pathway GO:2001234 104 0.026
regulation of intracellular transport GO:0032386 159 0.026
response to hydrogen peroxide GO:0042542 32 0.026
myeloid cell differentiation GO:0030099 233 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
Human Yeast
nucleoside monophosphate metabolic process GO:0009123 85 0.025
Human Yeast
actomyosin structure organization GO:0031032 56 0.025
positive regulation of cell cycle g1 s phase transition GO:1902808 9 0.025
positive regulation of cell cycle process GO:0090068 61 0.025
histone h3 k9 methylation GO:0051567 17 0.025
neuroblast differentiation GO:0014016 2 0.025
cellular response to abiotic stimulus GO:0071214 56 0.025
muscle contraction GO:0006936 101 0.025
chromosome separation GO:0051304 14 0.025
circulatory system process GO:0003013 197 0.024
carbohydrate derivative catabolic process GO:1901136 231 0.024
Human Yeast
protein import GO:0017038 101 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.024
Human Yeast
regulation of neuron projection development GO:0010975 169 0.024
developmental cell growth GO:0048588 84 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
positive regulation of protein transport GO:0051222 93 0.024
inner cell mass cell proliferation GO:0001833 15 0.024
apoptotic cell clearance GO:0043277 17 0.024
Worm
regulation of centriole replication GO:0046599 1 0.024
establishment of protein localization to organelle GO:0072594 118 0.024
stem cell differentiation GO:0048863 268 0.024
nucleotide catabolic process GO:0009166 217 0.023
Human Yeast
skin development GO:0043588 220 0.023
cellular response to antibiotic GO:0071236 4 0.023
branching morphogenesis of an epithelial tube GO:0048754 159 0.023
histone methylation GO:0016571 71 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
regulation of meiosis i GO:0060631 7 0.023
negative regulation of protein modification process GO:0031400 163 0.023
maintenance of location GO:0051235 89 0.023
response to alcohol GO:0097305 48 0.023
homeostasis of number of cells GO:0048872 210 0.023
positive regulation of histone methylation GO:0031062 16 0.022
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.022
negative regulation of cell activation GO:0050866 111 0.022
developmental growth involved in morphogenesis GO:0060560 138 0.022
lymphocyte proliferation GO:0046651 164 0.022
cellular protein complex assembly GO:0043623 116 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
positive regulation of cytoplasmic transport GO:1903651 40 0.022
microtubule based process GO:0007017 236 0.022
Fly
cellular response to external stimulus GO:0071496 88 0.022
protein methylation GO:0006479 81 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
Human Yeast
atp catabolic process GO:0006200 55 0.021
Human Yeast
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.021
dna duplex unwinding GO:0032508 7 0.021
negative regulation of neuron apoptotic process GO:0043524 92 0.021
body morphogenesis GO:0010171 45 0.021
nuclear export GO:0051168 34 0.020
urogenital system development GO:0001655 261 0.020
negative regulation of ras protein signal transduction GO:0046580 18 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
morphogenesis of a branching epithelium GO:0061138 193 0.020
angiogenesis GO:0001525 201 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
Human Yeast
positive regulation of histone modification GO:0031058 28 0.020
regulation of cell activation GO:0050865 289 0.020
cellular response to metal ion GO:0071248 31 0.020
production of molecular mediator of immune response GO:0002440 103 0.020
axon guidance GO:0007411 141 0.019
respiratory system development GO:0060541 190 0.019
positive regulation of protein modification process GO:0031401 299 0.019
regulation of dna recombination GO:0000018 34 0.019
peptidyl lysine modification GO:0018205 77 0.019
leukocyte migration GO:0050900 124 0.019
anatomical structure homeostasis GO:0060249 145 0.019
protein processing GO:0016485 163 0.019
regulation of membrane potential GO:0042391 192 0.019
positive regulation of epithelial cell proliferation GO:0050679 68 0.019
coenzyme metabolic process GO:0006732 52 0.019
regulation of multi organism process GO:0043900 111 0.019
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.019
blood vessel morphogenesis GO:0048514 285 0.018
positive regulation of histone h3 k9 methylation GO:0051574 4 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
mitotic cytokinesis GO:0000281 4 0.018
zymogen activation GO:0031638 41 0.018
cell junction organization GO:0034330 77 0.018
action potential GO:0001508 78 0.018
response to temperature stimulus GO:0009266 55 0.018
regulation of cell cycle g2 m phase transition GO:1902749 10 0.018
regulation of vesicle mediated transport GO:0060627 139 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
notch signaling pathway GO:0007219 71 0.018
regulation of binding GO:0051098 111 0.018
striated muscle contraction GO:0006941 45 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
gtp catabolic process GO:0006184 143 0.017
multicellular organismal aging GO:0010259 24 0.017
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.017
regulation of gtp catabolic process GO:0033124 113 0.017
muscle cell differentiation GO:0042692 261 0.017
positive regulation of myeloid cell differentiation GO:0045639 43 0.016
internal protein amino acid acetylation GO:0006475 42 0.016
stem cell maintenance GO:0019827 130 0.016
regulation of myeloid cell differentiation GO:0045637 96 0.016
regulation of dna methylation GO:0044030 12 0.016
establishment of rna localization GO:0051236 18 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.016
negative regulation of phagocytosis GO:0050765 4 0.016
regulation of chromatin silencing GO:0031935 2 0.016
lipid biosynthetic process GO:0008610 179 0.016
response to muscle inactivity involved in regulation of muscle adaptation GO:0014877 4 0.016
protein oligomerization GO:0051259 67 0.016
positive regulation of nucleotide catabolic process GO:0030813 88 0.016
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.016
positive regulation of gene silencing by mirna GO:2000637 1 0.016
regulation of striated muscle cell differentiation GO:0051153 81 0.016
response to nutrient levels GO:0031667 109 0.016
mature dendritic cell differentiation GO:0097029 3 0.016
spermatid development GO:0007286 108 0.016
cardiac muscle contraction GO:0060048 32 0.016
gland development GO:0048732 330 0.015
regulation of atp metabolic process GO:1903578 17 0.015
inflammatory response GO:0006954 244 0.015
intracellular mrna localization GO:0008298 4 0.015
positive regulation of chromatin modification GO:1903310 28 0.015
chromatin remodeling GO:0006338 32 0.015
protein heterooligomerization GO:0051291 14 0.015
sulfur compound metabolic process GO:0006790 100 0.015
maternal process involved in female pregnancy GO:0060135 32 0.015
negative regulation of dna replication GO:0008156 4 0.015
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.014
peptidyl lysine acetylation GO:0018394 45 0.014
neural retina development GO:0003407 41 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
regulation of cell projection organization GO:0031344 206 0.014
negative regulation of neuron death GO:1901215 98 0.014
positive regulation of kinase activity GO:0033674 155 0.014
skeletal system development GO:0001501 356 0.014
citrate metabolic process GO:0006101 3 0.014
somatic diversification of immunoglobulins GO:0016445 43 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.014
muscle system process GO:0003012 141 0.014
leukocyte differentiation GO:0002521 342 0.014
mrna export from nucleus GO:0006406 11 0.014
regulation of hormone levels GO:0010817 211 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
exocrine system development GO:0035272 45 0.014
neuron projection guidance GO:0097485 141 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
negative regulation of wnt signaling pathway GO:0030178 73 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.013
mrna metabolic process GO:0016071 84 0.013
response to oxygen levels GO:0070482 62 0.013
response to hypoxia GO:0001666 58 0.013
neuron migration GO:0001764 122 0.013
ossification GO:0001503 216 0.013

Mcm4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
hereditary sensory neuropathy DOID:0050548 0 0.106
peripheral neuropathy DOID:0060053 0 0.106
disease of anatomical entity DOID:7 0 0.106
nervous system disease DOID:863 0 0.106
neuropathy DOID:870 0 0.106
physical disorder DOID:0080015 0 0.072
disease of cellular proliferation DOID:14566 0 0.037
cancer DOID:162 0 0.024
organ system cancer DOID:0050686 0 0.024