|
|
negative regulation of neurotrophin trk receptor signaling pathway
|
GO:0051387 |
2 |
0.818
|
|
|
|
negative regulation of gtpase activity
|
GO:0034260 |
6 |
0.706
|
|
|
|
negative regulation of ras gtpase activity
|
GO:0034261 |
3 |
0.554
|
|
|
|
negative regulation of nucleoside metabolic process
|
GO:0045978 |
11 |
0.501
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.404
|
|
|
|
negative regulation of gtp catabolic process
|
GO:0033125 |
7 |
0.379
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.344
|
|
|
|
regulation of neurotrophin trk receptor signaling pathway
|
GO:0051386 |
4 |
0.336
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.318
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.310
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.308
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.305
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.290
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.264
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.262
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.260
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.254
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.252
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.244
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.244
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.243
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.242
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.241
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.239
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.235
|
Mouse |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.232
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.222
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.220
|
|
|
|
negative regulation of purine nucleotide metabolic process
|
GO:1900543 |
16 |
0.216
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.213
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.208
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.207
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.206
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.205
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.201
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.197
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.195
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.193
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.191
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.189
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.188
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.186
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.183
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.182
|
|
|
|
negative regulation of purine nucleotide catabolic process
|
GO:0033122 |
9 |
0.182
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.182
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.182
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.175
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.174
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.171
|
Fly |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.168
|
|
|
|
lung growth
|
GO:0060437 |
2 |
0.162
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.156
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.155
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.154
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.151
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.150
|
|
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
8 |
0.147
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.143
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.142
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.142
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.141
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.141
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.134
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.129
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.123
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.122
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.121
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.120
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.120
|
|
|
|
negative regulation of nucleotide metabolic process
|
GO:0045980 |
16 |
0.119
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.118
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.116
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.115
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.114
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.113
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.112
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.111
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.111
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.109
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.109
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.107
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.103
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.102
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.100
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.099
|
Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.098
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.096
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.095
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.095
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.095
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.093
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.093
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.093
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.092
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.091
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.089
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.088
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.087
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.082
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.081
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.080
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.080
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.080
|
|
|
|
negative regulation of nucleotide catabolic process
|
GO:0030812 |
9 |
0.080
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.078
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.078
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.078
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.077
|
|
|
|
specification of organ identity
|
GO:0010092 |
30 |
0.074
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.072
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.071
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.069
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.069
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.066
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.065
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.065
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.065
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.065
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.064
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.064
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.063
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.063
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.062
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.062
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.062
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.060
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.060
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.060
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.059
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.058
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.057
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.057
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.055
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.055
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.055
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.054
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.053
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.053
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.053
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.052
|
Mouse |
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.051
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.050
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.050
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.050
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.049
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.048
|
|
|
|
spindle localization
|
GO:0051653 |
22 |
0.047
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.047
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.047
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.047
|
Mouse |
|
|
forebrain development
|
GO:0030900 |
302 |
0.047
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.047
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.046
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.046
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.046
|
Fly |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.046
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.044
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.044
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.044
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
46 |
0.043
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.043
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.043
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.043
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.042
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.042
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.042
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.041
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.041
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.041
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.041
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.040
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.040
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.040
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
47 |
0.039
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.039
|
Fly |
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.039
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.038
|
|
|
|
axis elongation
|
GO:0003401 |
30 |
0.038
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.038
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.037
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.037
|
Mouse |
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.037
|
Mouse Fly |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.037
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.036
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.036
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.036
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.036
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.036
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.036
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.035
|
Mouse |
|
|
establishment of spindle localization
|
GO:0051293 |
19 |
0.035
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.035
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.034
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.034
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.034
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.034
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.034
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.034
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.034
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.033
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.033
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.033
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.033
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.033
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.032
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.032
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.032
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.031
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.030
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.030
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.029
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.029
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.029
|
|
|
|
gene silencing by mirna
|
GO:0035195 |
10 |
0.029
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.029
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.029
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.029
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.028
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.028
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.027
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.027
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.026
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.026
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.026
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.026
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.025
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.025
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.025
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.025
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.025
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.025
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.025
|
|
|
|
retinal blood vessel morphogenesis
|
GO:0061304 |
3 |
0.025
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.025
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.025
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.025
|
|
|
|
rhombomere formation
|
GO:0021594 |
1 |
0.024
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.024
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.024
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.024
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.024
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.024
|
Fly |
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.024
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.024
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.024
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.024
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.023
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.023
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.023
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.023
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.023
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.023
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.023
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.023
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.023
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.022
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.022
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.022
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.022
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.022
|
|
|
|
positive regulation of gene silencing by mirna
|
GO:2000637 |
1 |
0.022
|
|
|
|
negative regulation of osteoblast differentiation
|
GO:0045668 |
30 |
0.022
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.022
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.022
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.021
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.021
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.021
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.021
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.021
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.021
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.021
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.021
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.021
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.021
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.020
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.020
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.020
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.020
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.020
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.020
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.020
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.020
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.020
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.020
|
|
|
|
regulation of branching involved in salivary gland morphogenesis by extracellular matrix epithelial cell signaling
|
GO:0060668 |
1 |
0.019
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.019
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.019
|
|
|
|
developmental induction
|
GO:0031128 |
34 |
0.019
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.019
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.019
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.019
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.019
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.019
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.019
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.019
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.019
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.019
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.019
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.019
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.019
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.019
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.019
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.019
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.019
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.018
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.018
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.018
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.018
|
|
|
|
regulation of organ formation
|
GO:0003156 |
34 |
0.018
|
|
|
|
negative regulation of peptidyl threonine phosphorylation
|
GO:0010801 |
6 |
0.018
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.018
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.018
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.018
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.018
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.018
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.018
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.018
|
|
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.018
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.018
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.017
|
Fly |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.017
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.017
|
Mouse |
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.017
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.017
|
|
|
|
rhombomere morphogenesis
|
GO:0021593 |
2 |
0.017
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.017
|
|
|
|
gene silencing by rna
|
GO:0031047 |
19 |
0.017
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.017
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.017
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.017
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.017
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.017
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.017
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.017
|
|
|
|
response to sterol
|
GO:0036314 |
4 |
0.017
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
10 |
0.017
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.017
|
|
|
|
vascular wound healing
|
GO:0061042 |
3 |
0.017
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.017
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.017
|
|
|
|
regulation of transcription from rna polymerase iii promoter
|
GO:0006359 |
2 |
0.017
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.017
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.017
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.017
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.016
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.016
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.016
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.016
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.016
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.016
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
35 |
0.016
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.016
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.016
|
|
|
|
midgut development
|
GO:0007494 |
4 |
0.016
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.016
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.016
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.016
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.016
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.016
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.016
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.016
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.016
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.016
|
|
|
|
learning
|
GO:0007612 |
98 |
0.016
|
|
|
|
trunk neural crest cell migration
|
GO:0036484 |
4 |
0.016
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.016
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.016
|
|
|
|
negative regulation of smooth muscle cell migration
|
GO:0014912 |
2 |
0.016
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.016
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.016
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.015
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.015
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.015
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.015
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.015
|
|
|
|
positive regulation of transcription from rna polymerase i promoter
|
GO:0045943 |
3 |
0.015
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.015
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.015
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.015
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.015
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.015
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.015
|
|
|
|
regulation of cell migration involved in sprouting angiogenesis
|
GO:0090049 |
4 |
0.015
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
56 |
0.015
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.015
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.015
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.014
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.014
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.014
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.014
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.014
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.014
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.014
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.014
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.014
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.014
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.014
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
10 |
0.014
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.014
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.014
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.014
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.014
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.014
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.014
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.014
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.014
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.014
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.014
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.014
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.014
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.014
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.014
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
18 |
0.014
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.014
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.014
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.014
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.014
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.014
|
|
|
|
metanephric glomerular basement membrane development
|
GO:0072274 |
1 |
0.014
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.014
|
|
|
|
positive regulation of posttranscriptional gene silencing
|
GO:0060148 |
1 |
0.014
|
|
|
|
establishment of spindle orientation
|
GO:0051294 |
15 |
0.014
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.014
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.014
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.014
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.013
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.013
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.013
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.013
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.013
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.013
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.013
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.013
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.013
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.013
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.013
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.013
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.013
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.013
|
|
|
|
negative regulation of catenin import into nucleus
|
GO:0035414 |
2 |
0.013
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.013
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.013
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.013
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.013
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.013
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.013
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.013
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.013
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.013
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.013
|
|
|
|
inter male aggressive behavior
|
GO:0002121 |
3 |
0.013
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.013
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.013
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.013
|
|
|
|
formation of organ boundary
|
GO:0010160 |
1 |
0.013
|
|
|
|
growth involved in heart morphogenesis
|
GO:0003241 |
4 |
0.013
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.013
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.012
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.012
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.012
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.012
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.012
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.012
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.012
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.012
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.012
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.012
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.012
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.012
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
4 |
0.012
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
28 |
0.012
|
Fly |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.012
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.012
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.012
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.012
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.012
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.012
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.012
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.012
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.012
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.012
|
|
|
|
glycosaminoglycan metabolic process
|
GO:0030203 |
34 |
0.012
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.012
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.012
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.012
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.012
|
|
