Mus musculus

134 known processes

Col2a1

collagen, type II, alpha 1

(Aliases: MGC90638,Col2a-1,Col2,Dmm,Del1,Col2a)

Col2a1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
skeletal system morphogenesis GO:0048705 203 0.999
cartilage development GO:0051216 140 0.997
skeletal system development GO:0001501 356 0.996
embryonic skeletal system morphogenesis GO:0048704 91 0.988
Human Mouse
appendage morphogenesis GO:0035107 149 0.987
limb morphogenesis GO:0035108 149 0.976
axon guidance GO:0007411 141 0.975
pallium development GO:0021543 120 0.972
Mouse
forebrain development GO:0030900 302 0.968
Mouse
sensory organ morphogenesis GO:0090596 242 0.966
chondrocyte development GO:0002063 24 0.962
Mouse
proteoglycan metabolic process GO:0006029 38 0.958
embryonic skeletal system development GO:0048706 120 0.958
Human Mouse
chondrocyte differentiation GO:0002062 72 0.956
bone morphogenesis GO:0060349 78 0.950
stem cell development GO:0048864 219 0.942
telencephalon development GO:0021537 186 0.941
Mouse
appendage development GO:0048736 166 0.939
connective tissue development GO:0061448 179 0.932
bmp signaling pathway GO:0030509 93 0.930
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.904
ossification GO:0001503 216 0.903
endoderm development GO:0007492 45 0.897
hypophysis morphogenesis GO:0048850 3 0.894
regionalization GO:0003002 337 0.893
forebrain neuron fate commitment GO:0021877 13 0.884
cardiac muscle tissue morphogenesis GO:0055008 44 0.882
Mouse
digestive tract morphogenesis GO:0048546 147 0.875
heart morphogenesis GO:0003007 178 0.874
ear morphogenesis GO:0042471 118 0.869
diencephalon development GO:0021536 63 0.869
bone development GO:0060348 120 0.865
neural tube development GO:0021915 160 0.857
astrocyte fate commitment GO:0060018 4 0.854
lens morphogenesis in camera type eye GO:0002089 24 0.853
epithelial tube morphogenesis GO:0060562 303 0.845
ureteric bud development GO:0001657 94 0.844
embryonic organ morphogenesis GO:0048562 276 0.837
mesenchymal cell differentiation GO:0048762 107 0.833
mesenchymal cell development GO:0014031 93 0.819
metanephric nephron tubule formation GO:0072289 4 0.818
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.817
neuron apoptotic process GO:0051402 142 0.816
limb development GO:0060173 166 0.814
endodermal cell fate determination GO:0007493 2 0.812
formation of primary germ layer GO:0001704 77 0.811
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.799
regulation of chondrocyte differentiation GO:0032330 33 0.793
central nervous system neuron differentiation GO:0021953 162 0.791
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.790
determination of heart left right asymmetry GO:0061371 48 0.789
cellular component assembly involved in morphogenesis GO:0010927 139 0.788
endochondral bone morphogenesis GO:0060350 50 0.775
gastrulation GO:0007369 116 0.757
midbrain hindbrain boundary maturation GO:0021732 1 0.752
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.749
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.749
notochord development GO:0030903 20 0.744
stem cell differentiation GO:0048863 268 0.740
leukocyte differentiation GO:0002521 342 0.738
t cell activation GO:0042110 289 0.735
palate development GO:0060021 76 0.730
epithelial to mesenchymal transition GO:0001837 47 0.729
forebrain regionalization GO:0021871 25 0.724
renal vesicle induction GO:0072034 3 0.722
regulation of stem cell differentiation GO:2000736 50 0.722
muscle cell differentiation GO:0042692 261 0.709
multicellular organismal homeostasis GO:0048871 164 0.706
extracellular structure organization GO:0043062 148 0.702
kidney epithelium development GO:0072073 121 0.687
tendon cell differentiation GO:0035990 4 0.682
camera type eye development GO:0043010 266 0.680
cardiac muscle tissue development GO:0048738 130 0.678
Mouse
primary neural tube formation GO:0014020 95 0.669
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.666
regulation of rac gtpase activity GO:0032314 13 0.653
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.653
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.650
negative regulation of epithelial cell proliferation GO:0050680 64 0.646
retina morphogenesis in camera type eye GO:0060042 45 0.643
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.642
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.642
nephric duct formation GO:0072179 4 0.636
aorta morphogenesis GO:0035909 22 0.625
Mouse
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.624
primary prostatic bud elongation GO:0060516 2 0.624
lymphocyte differentiation GO:0030098 242 0.618
morphogenesis of embryonic epithelium GO:0016331 159 0.617
blood vessel morphogenesis GO:0048514 285 0.606
Mouse
trachea cartilage morphogenesis GO:0060535 4 0.601
neuron projection guidance GO:0097485 141 0.593
neural tube closure GO:0001843 90 0.588
negative regulation of cell development GO:0010721 169 0.582
Mouse
ear development GO:0043583 200 0.580
pancreatic a cell fate commitment GO:0003326 2 0.573
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.572
pituitary gland development GO:0021983 38 0.572
digestive tract development GO:0048565 190 0.570
Mouse
digestive system development GO:0055123 200 0.564
Mouse
glial cell development GO:0021782 54 0.560
mesonephric tubule development GO:0072164 94 0.560
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.559
negative regulation of nervous system development GO:0051961 156 0.559
Mouse
regulation of muscle tissue development GO:1901861 97 0.558
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.558
tissue homeostasis GO:0001894 115 0.552
muscle tissue development GO:0060537 308 0.548
Mouse
negative regulation of molecular function GO:0044092 258 0.548
head morphogenesis GO:0060323 34 0.545
Mouse
mesenchyme development GO:0060485 152 0.543
negative regulation of prostatic bud formation GO:0060686 4 0.538
cerebellum formation GO:0021588 1 0.532
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 4 0.529
fat cell differentiation GO:0045444 160 0.527
forebrain morphogenesis GO:0048853 17 0.521
forebrain neuron differentiation GO:0021879 52 0.520
axonogenesis GO:0007409 274 0.517
striated muscle cell development GO:0055002 125 0.517
glial cell differentiation GO:0010001 131 0.514
male sex differentiation GO:0046661 109 0.514
neuron migration GO:0001764 122 0.510
Mouse
embryonic limb morphogenesis GO:0030326 126 0.508
ventral midline development GO:0007418 4 0.508
limbic system development GO:0021761 72 0.508
regulation of glial cell differentiation GO:0045685 41 0.504
forebrain generation of neurons GO:0021872 63 0.501
embryonic epithelial tube formation GO:0001838 130 0.493
regulation of retina development in camera type eye GO:1902866 3 0.492
protein processing GO:0016485 163 0.484
pancreatic pp cell fate commitment GO:0003329 2 0.482
regulation of cartilage development GO:0061035 44 0.482
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.481
cardiocyte differentiation GO:0035051 87 0.481
anatomical structure homeostasis GO:0060249 145 0.480
positive regulation of cardioblast differentiation GO:0051891 3 0.473
muscle cell development GO:0055001 133 0.468
embryonic camera type eye development GO:0031076 36 0.465
myeloid leukocyte differentiation GO:0002573 119 0.463
multicellular organismal metabolic process GO:0044236 28 0.461
detection of external stimulus GO:0009581 61 0.460
positive regulation of immature t cell proliferation GO:0033091 4 0.460
astrocyte differentiation GO:0048708 43 0.460
cell proliferation in forebrain GO:0021846 30 0.459
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.458
positive regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014718 2 0.455
actin cytoskeleton organization GO:0030036 220 0.453
cell fate commitment GO:0045165 210 0.453
epithelial cell development GO:0002064 159 0.452
metanephric dct cell differentiation GO:0072240 3 0.451
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.450
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.449
inner ear morphogenesis GO:0042472 101 0.446
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.443
embryonic heart tube morphogenesis GO:0003143 51 0.440
mesoderm morphogenesis GO:0048332 64 0.438
glial cell migration GO:0008347 7 0.436
alpha beta t cell differentiation GO:0046632 69 0.433
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.427
globus pallidus development GO:0021759 2 0.427
osteoblast development GO:0002076 17 0.425
anterior commissure morphogenesis GO:0021960 6 0.423
central nervous system vasculogenesis GO:0022009 3 0.423
positive regulation of neuron apoptotic process GO:0043525 25 0.422
segmentation GO:0035282 93 0.421
glycoprotein metabolic process GO:0009100 116 0.420
protein maturation GO:0051604 176 0.418
embryonic appendage morphogenesis GO:0035113 126 0.414
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.414
retina development in camera type eye GO:0060041 119 0.409
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.409
smooth muscle tissue development GO:0048745 22 0.408
Mouse
axis elongation involved in somitogenesis GO:0090245 4 0.407
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.407
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.403
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.402
positive regulation of ossification GO:0045778 47 0.399
regulation of bmp signaling pathway GO:0030510 60 0.398
paramesonephric duct development GO:0061205 3 0.395
negative regulation of mesodermal cell fate specification GO:0042662 3 0.394
regulation of epithelial cell proliferation GO:0050678 141 0.393
positive regulation of transcription via serum response element binding GO:0010735 1 0.392
diencephalon morphogenesis GO:0048852 6 0.390
spinal cord patterning GO:0021511 25 0.389
t cell differentiation GO:0030217 174 0.383
optic nerve formation GO:0021634 1 0.382
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.382
auditory receptor cell fate determination GO:0042668 3 0.382
lung induction GO:0060492 3 0.381
regulation of epithelial to mesenchymal transition GO:0010717 22 0.381
rho protein signal transduction GO:0007266 32 0.380
Mouse
cerebral cortex neuron differentiation GO:0021895 19 0.377
cell type specific apoptotic process GO:0097285 268 0.376
negative regulation of chondrocyte differentiation GO:0032331 13 0.375
mitral valve development GO:0003174 4 0.374
endodermal cell fate specification GO:0001714 4 0.374
positive regulation of cell development GO:0010720 237 0.373
spinal cord development GO:0021510 81 0.367
cell differentiation in spinal cord GO:0021515 53 0.367
gland development GO:0048732 330 0.366
central nervous system neuron development GO:0021954 67 0.364
mitral valve morphogenesis GO:0003183 4 0.363
protein alkylation GO:0008213 81 0.363
midbrain development GO:0030901 35 0.362
renal outer medulla development GO:0072054 2 0.360
ventricular cardiac myofibril assembly GO:0055005 3 0.359
stem cell fate specification GO:0048866 3 0.359
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.358
retinal ganglion cell axon guidance GO:0031290 18 0.356
renal inner medulla development GO:0072053 3 0.355
ureteric bud morphogenesis GO:0060675 62 0.352
nephron epithelium morphogenesis GO:0072088 68 0.352
regulation of ras protein signal transduction GO:0046578 114 0.349
Mouse
regulation of gliogenesis GO:0014013 50 0.349
regulation of neuron death GO:1901214 134 0.349
limb bud formation GO:0060174 10 0.347
cell proliferation in hindbrain GO:0021534 10 0.346
negative regulation of gastrulation GO:2000542 3 0.344
pharyngeal system development GO:0060037 17 0.344
prostate gland morphogenetic growth GO:0060737 4 0.339
endoderm formation GO:0001706 20 0.336
inner cell mass cellular morphogenesis GO:0001828 1 0.331
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.330
positive regulation of stem cell proliferation GO:2000648 59 0.327
morphogenesis of a branching structure GO:0001763 203 0.326
plasma cell differentiation GO:0002317 3 0.325
regulation of osteoblast differentiation GO:0045667 67 0.324
wnt signaling pathway GO:0016055 188 0.322
regulation of wnt signaling pathway GO:0030111 123 0.318
cardiac ventricle development GO:0003231 83 0.316
Mouse
striated muscle tissue development GO:0014706 293 0.314
Mouse
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.310
embryonic heart tube development GO:0035050 65 0.310
somitogenesis GO:0001756 69 0.309
glial cell fate commitment GO:0021781 14 0.306
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.306
epithelial cell proliferation involved in prostate gland development GO:0060767 11 0.306
asymmetric neuroblast division GO:0055059 1 0.305
endodermal cell fate commitment GO:0001711 12 0.304
positive regulation of hh target transcription factor activity GO:0007228 3 0.304
cell fate specification GO:0001708 72 0.302
branching morphogenesis of an epithelial tube GO:0048754 159 0.301
spinal cord dorsal ventral patterning GO:0021513 23 0.299
positive regulation of metanephric dct cell differentiation GO:2000594 2 0.298
negative regulation of neuron differentiation GO:0045665 101 0.298
developmental maturation GO:0021700 193 0.297
synaptic transmission GO:0007268 329 0.291
auditory receptor cell fate specification GO:0042667 1 0.290
extracellular matrix organization GO:0030198 147 0.289
purine containing compound catabolic process GO:0072523 213 0.287
small gtpase mediated signal transduction GO:0007264 97 0.286
Mouse
cartilage condensation GO:0001502 18 0.284
development of primary male sexual characteristics GO:0046546 88 0.283
male gonad development GO:0008584 88 0.282
regulation of organ morphogenesis GO:2000027 144 0.281
regulation of protein geranylgeranylation GO:2000539 2 0.277
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.273
regulation of alpha beta t cell differentiation GO:0046637 35 0.272
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.266
Mouse
nephron tubule development GO:0072080 84 0.265
nephron epithelium development GO:0072009 92 0.263
paraxial mesodermal cell fate commitment GO:0048343 2 0.263
negative regulation of cell cycle GO:0045786 123 0.262
branching involved in prostate gland morphogenesis GO:0060442 15 0.261
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.261
paraxial mesodermal cell differentiation GO:0048342 2 0.259
prenylation GO:0097354 3 0.256
tendon formation GO:0035992 4 0.254
gliogenesis GO:0042063 141 0.254
negative regulation of cartilage development GO:0061037 17 0.254
mesonephric duct morphogenesis GO:0072180 4 0.253
morphogenesis of a branching epithelium GO:0061138 193 0.252
myotube differentiation GO:0014902 105 0.251
nephron morphogenesis GO:0072028 69 0.250
negative regulation of proteolysis GO:0045861 74 0.250
germ line sex determination GO:0018992 3 0.248
positive regulation of ureteric bud formation GO:0072107 3 0.245
regulation of neuron differentiation GO:0045664 281 0.245
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.242
regulation of nucleoside metabolic process GO:0009118 130 0.242
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.242
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.241
epithelial tube formation GO:0072175 130 0.236
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.235
positive regulation of apoptotic process GO:0043065 217 0.234
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.233
locomotory behavior GO:0007626 195 0.233
regulation of astrocyte differentiation GO:0048710 20 0.232
regulation of biomineral tissue development GO:0070167 33 0.231
positive regulation of immature t cell proliferation in thymus GO:0033092 3 0.230
lens development in camera type eye GO:0002088 62 0.230
oligodendrocyte development GO:0014003 20 0.229
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.229
hindbrain formation GO:0021576 1 0.227
bone trabecula formation GO:0060346 9 0.227
Mouse
cell fate specification involved in pattern specification GO:0060573 11 0.226
regulation of protein transport GO:0051223 163 0.226
positive regulation of cellular amine metabolic process GO:0033240 5 0.224
metanephric loop of henle development GO:0072236 4 0.223
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.223
rac protein signal transduction GO:0016601 13 0.223
organ induction GO:0001759 21 0.222
atrial cardiac muscle cell development GO:0055014 2 0.221
cardiac ventricle morphogenesis GO:0003208 50 0.216
Mouse
regulation of cell adhesion GO:0030155 154 0.216
Mouse
germ cell development GO:0007281 185 0.214
second messenger mediated signaling GO:0019932 73 0.214
embryonic digit morphogenesis GO:0042733 56 0.213
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.213
skin development GO:0043588 220 0.212
Mouse
protein geranylgeranylation GO:0018344 3 0.211
forebrain ventricular zone progenitor cell division GO:0021869 6 0.210
negative regulation of bmp signaling pathway GO:0030514 35 0.208
odontogenesis of dentin containing tooth GO:0042475 66 0.208
stem cell proliferation GO:0072089 117 0.208
neural precursor cell proliferation GO:0061351 121 0.207
nucleoside metabolic process GO:0009116 246 0.206
left lung development GO:0060459 4 0.205
otic vesicle development GO:0071599 14 0.205
trabecula morphogenesis GO:0061383 40 0.202
Mouse
myoblast differentiation GO:0045445 52 0.199
cellular amine metabolic process GO:0044106 44 0.199
regulation of cellular protein catabolic process GO:1903362 61 0.198
positive regulation of cartilage development GO:0061036 18 0.198
regulation of mesenchymal cell proliferation GO:0010464 37 0.198
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.197
regulation of intracellular transport GO:0032386 159 0.196
brain morphogenesis GO:0048854 32 0.196
neuron death GO:0070997 154 0.194
odontogenesis GO:0042476 78 0.193
negative regulation of reproductive process GO:2000242 31 0.192
protein autoprocessing GO:0016540 2 0.191
clara cell differentiation GO:0060486 4 0.191
regulation of cellular amine metabolic process GO:0033238 20 0.190
ventricular cardiac muscle tissue development GO:0003229 38 0.189
Mouse
mammary gland morphogenesis GO:0060443 54 0.189
spemann organizer formation GO:0060061 2 0.189
positive regulation of protein modification process GO:0031401 299 0.188
retinal rod cell differentiation GO:0060221 2 0.187
regulation of transcription from rna polymerase ii promoter involved in definitive endodermal cell fate specification GO:0060807 1 0.187
mesonephric duct formation GO:0072181 2 0.187
type b pancreatic cell differentiation GO:0003309 13 0.186
myeloid cell differentiation GO:0030099 233 0.185
endocardial cell differentiation GO:0060956 4 0.184
kidney rudiment formation GO:0072003 3 0.184
stem cell maintenance GO:0019827 130 0.184
ventral spinal cord development GO:0021517 48 0.179
lung field specification GO:0060424 3 0.178
eye photoreceptor cell differentiation GO:0001754 41 0.177
sensory perception GO:0007600 245 0.176
Human Mouse
positive regulation of growth GO:0045927 104 0.175
telencephalon regionalization GO:0021978 14 0.175
regulation of cardioblast differentiation GO:0051890 3 0.175
regulation of lens epithelial cell proliferation GO:2001109 1 0.175
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.174
smoothened signaling pathway GO:0007224 105 0.174
regulation of mapk cascade GO:0043408 248 0.173
mesonephric epithelium development GO:0072163 94 0.173
chemotaxis GO:0006935 247 0.173
cerebellar purkinje cell granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation GO:0021937 6 0.172
detection of stimulus GO:0051606 84 0.169
pancreatic pp cell differentiation GO:0003312 2 0.168
regulation of proteolysis GO:0030162 164 0.168
embryonic skeletal joint development GO:0072498 13 0.167
Human
establishment of endothelial blood brain barrier GO:0014045 3 0.167
cochlea morphogenesis GO:0090103 22 0.164
deltoid tuberosity development GO:0035993 3 0.164
spinal cord ventral commissure morphogenesis GO:0021965 2 0.163
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.163
positive regulation of programmed cell death GO:0043068 218 0.162
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.162
lens epithelial cell proliferation GO:0097166 1 0.161
regulation of neural precursor cell proliferation GO:2000177 70 0.161
forebrain radial glial cell differentiation GO:0021861 4 0.161
regulation of anatomical structure size GO:0090066 178 0.160
positive regulation of bmp signaling pathway GO:0030513 23 0.160
olfactory bulb interneuron development GO:0021891 7 0.159
artery development GO:0060840 53 0.158
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.157
Mouse
regulation of neuron projection development GO:0010975 169 0.156
developmental growth involved in morphogenesis GO:0060560 138 0.156
germ line stem cell division GO:0042078 2 0.154
nucleobase containing small molecule metabolic process GO:0055086 352 0.153
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.153
hemangioblast cell differentiation GO:0060217 1 0.153
positive regulation of mesonephros development GO:0061213 20 0.151
axial mesoderm formation GO:0048320 3 0.151
kidney development GO:0001822 213 0.150
central nervous system neuron axonogenesis GO:0021955 28 0.150
regulation of nucleocytoplasmic transport GO:0046822 73 0.149
gonad development GO:0008406 141 0.149
urogenital system development GO:0001655 261 0.149
skeletal muscle cell differentiation GO:0035914 66 0.148
neural tube patterning GO:0021532 43 0.148
collagen metabolic process GO:0032963 17 0.148
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.146
cell junction organization GO:0034330 77 0.146
regulation of neuron apoptotic process GO:0043523 122 0.145
canonical wnt signaling pathway GO:0060070 130 0.145
pyramidal neuron migration GO:0021852 1 0.144
cardiac cell fate determination GO:0060913 2 0.144
embryonic eye morphogenesis GO:0048048 29 0.143
embryonic heart tube formation GO:0003144 1 0.142
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.142
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.141
cell adhesion GO:0007155 329 0.141
Mouse
cardiac atrium development GO:0003230 24 0.140
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis GO:0060527 7 0.140
epithelial cell proliferation GO:0050673 174 0.140
developmental induction GO:0031128 34 0.139
mesenchymal stem cell maintenance involved in nephron morphogenesis GO:0072038 7 0.138
skeletal muscle fiber development GO:0048741 58 0.138
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.138
optic vesicle morphogenesis GO:0003404 2 0.137
floor plate morphogenesis GO:0033505 3 0.137
cardiac chamber development GO:0003205 108 0.137
Mouse
multicellular organismal macromolecule metabolic process GO:0044259 19 0.136
oogenesis GO:0048477 56 0.135
dorsal ventral neural tube patterning GO:0021904 28 0.135
regulation of purine nucleotide catabolic process GO:0033121 122 0.134
cervix development GO:0060067 2 0.134
regulation of cardiac muscle tissue development GO:0055024 31 0.134
notochord formation GO:0014028 5 0.134
peptidyl serine modification GO:0018209 83 0.133
respiratory system development GO:0060541 190 0.133
renal system development GO:0072001 225 0.133
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.133
proepicardium development GO:0003342 2 0.133
organelle assembly GO:0070925 177 0.132
metanephric mesenchymal cell proliferation involved in metanephros development GO:0072136 2 0.132
negative regulation of protein processing GO:0010955 79 0.132
male gamete generation GO:0048232 285 0.131
angiogenesis GO:0001525 201 0.131
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 12 0.131
lymphocyte proliferation GO:0046651 164 0.130
negative regulation of gliogenesis GO:0014014 23 0.129
protein localization to organelle GO:0033365 185 0.129
oligodendrocyte differentiation GO:0048709 53 0.128
prostate epithelial cord elongation GO:0060523 3 0.128
nucleoside phosphate catabolic process GO:1901292 222 0.127
negative regulation of kidney development GO:0090185 15 0.127
regulation of rac protein signal transduction GO:0035020 19 0.127
regulation of stem cell maintenance GO:2000036 17 0.126
response to fibroblast growth factor GO:0071774 47 0.126
cell cell signaling involved in cell fate commitment GO:0045168 35 0.126
nephron tubule morphogenesis GO:0072078 68 0.126
cardiac pacemaker cell fate commitment GO:0060927 1 0.126
regulation of cell cycle GO:0051726 281 0.126
respiratory tube development GO:0030323 167 0.123
spinal cord motor neuron differentiation GO:0021522 35 0.123
regulation of embryonic development GO:0045995 71 0.123
histone modification GO:0016570 159 0.123
closure of optic fissure GO:0061386 2 0.122
epithelial cell fate commitment GO:0072148 13 0.122
ascending aorta morphogenesis GO:0035910 3 0.121
somatotropin secreting cell differentiation GO:0060126 4 0.121
male germ line sex determination GO:0019100 2 0.121
frontal suture morphogenesis GO:0060364 2 0.121
ribonucleotide catabolic process GO:0009261 208 0.120
regulation of cellular amino acid metabolic process GO:0006521 5 0.120
biomineral tissue development GO:0031214 64 0.120
determination of left right symmetry GO:0007368 80 0.119
female gamete generation GO:0007292 74 0.119
cellular response to heparin GO:0071504 1 0.119
negative regulation of smooth muscle cell differentiation GO:0051151 4 0.119
lung development GO:0030324 164 0.118
negative regulation of lymphocyte differentiation GO:0045620 32 0.118
purine nucleoside catabolic process GO:0006152 205 0.117
cellular response to lipid GO:0071396 145 0.117
detection of mechanical stimulus involved in equilibrioception GO:0050973 2 0.117
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.117
locus ceruleus development GO:0021703 1 0.116
negative regulation of cell fate specification GO:0009996 4 0.116
cardiac septum morphogenesis GO:0060411 46 0.116
endodermal cell differentiation GO:0035987 14 0.115
development of primary sexual characteristics GO:0045137 143 0.115
negative regulation of neuron projection development GO:0010977 50 0.115
collagen fibril organization GO:0030199 32 0.114
regulation of anagen GO:0051884 1 0.114
purkinje myocyte differentiation GO:0003168 1 0.114
specification of organ identity GO:0010092 30 0.114
positive regulation of epithelial to mesenchymal transition GO:0010718 13 0.114
lung smooth muscle development GO:0061145 2 0.114
regulation of purine nucleotide metabolic process GO:1900542 169 0.114
atrioventricular node cell fate commitment GO:0060929 1 0.114
heart formation GO:0060914 16 0.113
regulation of stem cell division GO:2000035 4 0.113
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.113

Col2a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 1.000
Human
bone disease DOID:0080001 0 1.000
Human
disease of anatomical entity DOID:7 0 1.000
Human
musculoskeletal system disease DOID:17 0 1.000
Human
connective tissue disease DOID:65 0 1.000
Human
osteochondrodysplasia DOID:2256 0 0.953
Human
dysostosis DOID:1934 0 0.388
brachydactyly DOID:0050581 0 0.157