Mus musculus

22 known processes

Fbxl12

F-box and leucine-rich repeat protein 12

(Aliases: Fbl12,3110048D16Rik)

Fbxl12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.180
macromolecule catabolic process GO:0009057 281 0.090
cellular response to dna damage stimulus GO:0006974 207 0.082
regulation of cell cycle GO:0051726 281 0.067
regulation of cellular ketone metabolic process GO:0010565 66 0.058
dna repair GO:0006281 107 0.055
regulation of cellular amino acid metabolic process GO:0006521 5 0.053
cellular macromolecule catabolic process GO:0044265 206 0.049
modification dependent macromolecule catabolic process GO:0043632 133 0.048
peptidyl amino acid modification GO:0018193 336 0.044
organelle fission GO:0048285 170 0.044
Mouse
protein maturation GO:0051604 176 0.040
protein ubiquitination GO:0016567 171 0.040
Mouse
positive regulation of protein modification process GO:0031401 299 0.038
regulation of organelle organization GO:0033043 289 0.036
methylation GO:0032259 134 0.036
nuclear division GO:0000280 158 0.036
Mouse
positive regulation of apoptotic process GO:0043065 217 0.036
cellular amino acid metabolic process GO:0006520 103 0.034
protein localization to organelle GO:0033365 185 0.033
cellular amine metabolic process GO:0044106 44 0.032
chromatin modification GO:0016568 187 0.032
protein modification by small protein conjugation or removal GO:0070647 207 0.032
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.031
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.030
Mouse
regionalization GO:0003002 337 0.030
activation of immune response GO:0002253 138 0.030
positive regulation of innate immune response GO:0045089 80 0.029
ubiquitin dependent protein catabolic process GO:0006511 129 0.029
cellular ketone metabolic process GO:0042180 84 0.029
intracellular mrna localization GO:0008298 4 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
innate immune response GO:0045087 157 0.028
reactive oxygen species metabolic process GO:0072593 84 0.028
retrograde transport endosome to golgi GO:0042147 2 0.027
cell type specific apoptotic process GO:0097285 268 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.027
viral gene expression GO:0019080 3 0.027
oocyte axis specification GO:0007309 2 0.027
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
digestive system development GO:0055123 200 0.026
positive regulation of viral entry into host cell GO:0046598 3 0.026
rna processing GO:0006396 105 0.026
macromolecule methylation GO:0043414 120 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.025
response to radiation GO:0009314 165 0.025
mitochondrion organization GO:0007005 134 0.025
modification dependent protein catabolic process GO:0019941 133 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
positive regulation of cell death GO:0010942 224 0.024
protein polyubiquitination GO:0000209 33 0.024
protein polymerization GO:0051258 57 0.024
positive regulation of organelle organization GO:0010638 128 0.024
regulation of reactive oxygen species metabolic process GO:2000377 40 0.024
mapk cascade GO:0000165 281 0.023
cytokine production GO:0001816 319 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
regulation of protein maturation GO:1903317 96 0.023
phospholipid metabolic process GO:0006644 87 0.022
positive regulation of programmed cell death GO:0043068 218 0.022
amine metabolic process GO:0009308 45 0.022
regulation of mapk cascade GO:0043408 248 0.022
cytoplasmic transport GO:0016482 234 0.022
histone modification GO:0016570 159 0.022
cellular carbohydrate metabolic process GO:0044262 119 0.022
regulation of cellular response to stress GO:0080135 159 0.022
histone methylation GO:0016571 71 0.021
intracellular protein transport GO:0006886 204 0.021
protein catabolic process GO:0030163 221 0.021
covalent chromatin modification GO:0016569 163 0.021
cell division GO:0051301 120 0.021
mitotic cell cycle GO:0000278 195 0.021
Mouse
cellular lipid metabolic process GO:0044255 323 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
regulation of cytoskeleton organization GO:0051493 122 0.021
muscle cell differentiation GO:0042692 261 0.021
apoptotic signaling pathway GO:0097190 306 0.020
myeloid cell differentiation GO:0030099 233 0.020
meiotic nuclear division GO:0007126 115 0.020
meiotic cell cycle GO:0051321 122 0.020
regulation of protein catabolic process GO:0042176 108 0.020
defense response to other organism GO:0098542 197 0.020
chemotaxis GO:0006935 247 0.020
muscle tissue development GO:0060537 308 0.019
positive regulation of protein kinase activity GO:0045860 144 0.019
male gamete generation GO:0048232 285 0.019
carbohydrate biosynthetic process GO:0016051 74 0.019
oxidation reduction process GO:0055114 342 0.018
regulation of cytokine production GO:0001817 266 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
negative regulation of organelle organization GO:0010639 90 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
nitrogen compound transport GO:0071705 271 0.018
regulation of kinase activity GO:0043549 249 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
striated muscle tissue development GO:0014706 293 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
immune response regulating signaling pathway GO:0002764 125 0.018
regulation of cell cycle process GO:0010564 160 0.018
homeostasis of number of cells GO:0048872 210 0.018
positive regulation of cellular catabolic process GO:0031331 148 0.018
positive regulation of cellular component biogenesis GO:0044089 94 0.017
positive regulation of transferase activity GO:0051347 167 0.017
positive regulation of kinase activity GO:0033674 155 0.017
regulation of transferase activity GO:0051338 263 0.017
actin filament polymerization GO:0030041 44 0.017
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.017
myeloid cell homeostasis GO:0002262 114 0.017
negative regulation of molecular function GO:0044092 258 0.017
aromatic compound catabolic process GO:0019439 286 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
nucleotide metabolic process GO:0009117 332 0.017
immune response activating signal transduction GO:0002757 116 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
negative regulation of cell cycle GO:0045786 123 0.017
protein processing GO:0016485 163 0.016
glucose metabolic process GO:0006006 92 0.016
viral transcription GO:0019083 3 0.016
regulation of protein processing GO:0070613 96 0.016
negative regulation of viral transcription GO:0032897 3 0.016
multicellular organism growth GO:0035264 161 0.016
carbohydrate metabolic process GO:0005975 230 0.016
positive regulation of dna templated transcription elongation GO:0032786 2 0.016
interleukin 8 production GO:0032637 4 0.016
response to organonitrogen compound GO:0010243 246 0.016
regulation of insulin receptor signaling pathway GO:0046626 21 0.016
proteasomal protein catabolic process GO:0010498 98 0.016
Mouse
neuron death GO:0070997 154 0.016
positive regulation of apoptotic signaling pathway GO:2001235 95 0.016
germ cell development GO:0007281 185 0.015
regulation of neuron death GO:1901214 134 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
multi multicellular organism process GO:0044706 109 0.015
glucose homeostasis GO:0042593 128 0.015
regulation of protein kinase activity GO:0045859 232 0.015
regulation of defense response GO:0031347 233 0.015
positive regulation of viral genome replication GO:0045070 2 0.015
positive regulation of defense response GO:0031349 124 0.015
digestive tract morphogenesis GO:0048546 147 0.015
stem cell maintenance GO:0019827 130 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
nucleocytoplasmic transport GO:0006913 139 0.014
regulation of cell activation GO:0050865 289 0.014
ras protein signal transduction GO:0007265 77 0.014
chromatin organization GO:0006325 206 0.014
ossification GO:0001503 216 0.014
regulation of cellular component size GO:0032535 121 0.014
compound eye development GO:0048749 1 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
digestive tract development GO:0048565 190 0.014
skeletal muscle organ development GO:0060538 163 0.014
spermatogenesis GO:0007283 284 0.014
placenta development GO:0001890 140 0.014
cellular response to cytokine stimulus GO:0071345 189 0.013
regulation of actin nucleation GO:0051125 4 0.013
negative regulation of cell development GO:0010721 169 0.013
transcription from rna polymerase iii promoter GO:0006383 3 0.013
monosaccharide metabolic process GO:0005996 106 0.013
actin filament organization GO:0007015 113 0.013
small molecule biosynthetic process GO:0044283 132 0.013
actin cytoskeleton organization GO:0030036 220 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
nucleobase containing small molecule metabolic process GO:0055086 352 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
transmembrane transport GO:0055085 412 0.013
regulation of system process GO:0044057 200 0.013
regulation of blood pressure GO:0008217 93 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
negative regulation of immune system process GO:0002683 209 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
response to lipopolysaccharide GO:0032496 128 0.013
mitotic cell cycle process GO:1903047 159 0.013
Mouse
regulation of viral transcription GO:0046782 3 0.013
positive regulation of tor signaling GO:0032008 3 0.013
translation GO:0006412 93 0.013
regulation of homeostatic process GO:0032844 182 0.013
oocyte construction GO:0007308 2 0.013
dephosphorylation GO:0016311 129 0.013
skeletal system development GO:0001501 356 0.013
pole plasm assembly GO:0007315 2 0.013
cellular protein catabolic process GO:0044257 155 0.013
peptidyl serine phosphorylation GO:0018105 74 0.013
response to nutrient levels GO:0031667 109 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
development of primary sexual characteristics GO:0045137 143 0.012
synaptic transmission GO:0007268 329 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
hexose metabolic process GO:0019318 98 0.012
regulation of neuron differentiation GO:0045664 281 0.012
regulation of interleukin 8 production GO:0032677 3 0.012
regulation of cellular protein catabolic process GO:1903362 61 0.012
regulation of translation GO:0006417 71 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
regulation of anatomical structure size GO:0090066 178 0.012
stem cell differentiation GO:0048863 268 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.012
positive regulation of cell development GO:0010720 237 0.012
blood circulation GO:0008015 195 0.012
regulation of actin cytoskeleton organization GO:0032956 84 0.012
mitotic nuclear division GO:0007067 48 0.012
Mouse
lipid biosynthetic process GO:0008610 179 0.012
peptidyl lysine modification GO:0018205 77 0.012
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.012
regulation of chromosome organization GO:0033044 83 0.011
negative regulation of cytokine production GO:0001818 84 0.011
action potential GO:0001508 78 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
regulation of protein binding GO:0043393 60 0.011
regulation of vacuole organization GO:0044088 4 0.011
regulation of protein transport GO:0051223 163 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
response to peptide hormone GO:0043434 127 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
regulation of hydrolase activity GO:0051336 246 0.011
protein methylation GO:0006479 81 0.011
dna replication GO:0006260 52 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
response to acid chemical GO:0001101 111 0.011
response to peptide GO:1901652 136 0.011
cation transport GO:0006812 399 0.011
regulation of nuclear division GO:0051783 56 0.011
gonad development GO:0008406 141 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
innate immune response activating signal transduction GO:0002758 50 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
leukocyte differentiation GO:0002521 342 0.011
negative regulation of cell cycle process GO:0010948 69 0.011
response to drug GO:0042493 75 0.011
myosin filament organization GO:0031033 3 0.011
regulation of secretion GO:0051046 274 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
positive regulation of actin nucleation GO:0051127 3 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
circadian regulation of gene expression GO:0032922 48 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
positive regulation of protein catabolic process GO:0045732 60 0.011
smoothened signaling pathway GO:0007224 105 0.011
regulation of actin filament based process GO:0032970 99 0.011
fat cell differentiation GO:0045444 160 0.010
neuron apoptotic process GO:0051402 142 0.010
germ line stem cell division GO:0042078 2 0.010
regulation of embryonic development GO:0045995 71 0.010
adult behavior GO:0030534 135 0.010
response to organic cyclic compound GO:0014070 198 0.010
epithelial cell proliferation GO:0050673 174 0.010
purine ribonucleotide metabolic process GO:0009150 290 0.010
actin polymerization or depolymerization GO:0008154 54 0.010
nuclear transport GO:0051169 139 0.010
regulation of systemic arterial blood pressure GO:0003073 61 0.010
lymphocyte differentiation GO:0030098 242 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
regulation of intracellular protein transport GO:0033157 82 0.010

Fbxl12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011
immune system disease DOID:2914 0 0.011