Mus musculus

0 known processes

Fbxl16

F-box and leucine-rich repeat protein 16

(Aliases: Scirr1,BC042620)

Fbxl16 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.102
regulation of cellular ketone metabolic process GO:0010565 66 0.091
smoothened signaling pathway GO:0007224 105 0.081
cellular amino acid metabolic process GO:0006520 103 0.079
purine ribonucleotide metabolic process GO:0009150 290 0.069
regulation of membrane potential GO:0042391 192 0.068
negative regulation of cell development GO:0010721 169 0.068
small gtpase mediated signal transduction GO:0007264 97 0.064
rho protein signal transduction GO:0007266 32 0.062
negative regulation of nervous system development GO:0051961 156 0.061
negative regulation of molecular function GO:0044092 258 0.057
negative regulation of neuron differentiation GO:0045665 101 0.054
positive regulation of nervous system development GO:0051962 221 0.054
regulation of cell projection organization GO:0031344 206 0.053
membrane organization GO:0061024 245 0.052
axonogenesis GO:0007409 274 0.050
regulation of neuron differentiation GO:0045664 281 0.050
positive regulation of cell development GO:0010720 237 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.047
regulation of neuron projection development GO:0010975 169 0.047
regulation of cellular amine metabolic process GO:0033238 20 0.046
amine metabolic process GO:0009308 45 0.046
cellular ketone metabolic process GO:0042180 84 0.043
positive regulation of cellular amine metabolic process GO:0033240 5 0.042
positive regulation of cell projection organization GO:0031346 95 0.042
muscle cell differentiation GO:0042692 261 0.042
sensory organ morphogenesis GO:0090596 242 0.042
ribose phosphate metabolic process GO:0019693 291 0.042
muscle cell development GO:0055001 133 0.040
negative regulation of protein metabolic process GO:0051248 282 0.039
limb morphogenesis GO:0035108 149 0.039
cellular amine metabolic process GO:0044106 44 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.038
purine nucleotide metabolic process GO:0006163 302 0.037
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
nucleotide metabolic process GO:0009117 332 0.036
organic cyclic compound catabolic process GO:1901361 295 0.036
guanosine containing compound catabolic process GO:1901069 144 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
chemotaxis GO:0006935 247 0.034
axon guidance GO:0007411 141 0.033
modification dependent macromolecule catabolic process GO:0043632 133 0.033
tube formation GO:0035148 140 0.033
epithelial tube morphogenesis GO:0060562 303 0.032
regulation of hydrolase activity GO:0051336 246 0.032
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.032
synaptic transmission GO:0007268 329 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.031
ubiquitin dependent protein catabolic process GO:0006511 129 0.031
positive regulation of cell death GO:0010942 224 0.030
cell growth GO:0016049 130 0.030
regulation of hormone levels GO:0010817 211 0.030
striated muscle tissue development GO:0014706 293 0.030
protein catabolic process GO:0030163 221 0.030
nucleoside triphosphate metabolic process GO:0009141 230 0.029
regulation of cell growth GO:0001558 91 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
cellular lipid metabolic process GO:0044255 323 0.029
wnt signaling pathway GO:0016055 188 0.029
microtubule based process GO:0007017 236 0.028
regulation of cellular component biogenesis GO:0044087 181 0.028
cell adhesion GO:0007155 329 0.028
negative regulation of cell proliferation GO:0008285 296 0.028
regulation of apoptotic signaling pathway GO:2001233 197 0.028
peptidyl amino acid modification GO:0018193 336 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
muscle tissue development GO:0060537 308 0.027
endomembrane system organization GO:0010256 147 0.027
urogenital system development GO:0001655 261 0.027
purine nucleoside triphosphate metabolic process GO:0009144 226 0.027
microtubule cytoskeleton organization GO:0000226 157 0.027
neuron projection guidance GO:0097485 141 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.026
ribonucleoside catabolic process GO:0042454 206 0.026
macromolecule catabolic process GO:0009057 281 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.025
cation transmembrane transport GO:0098655 266 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.025
morphogenesis of embryonic epithelium GO:0016331 159 0.025
positive regulation of neuron projection development GO:0010976 79 0.025
purine nucleotide catabolic process GO:0006195 211 0.025
aromatic compound catabolic process GO:0019439 286 0.025
nucleoside metabolic process GO:0009116 246 0.025
neurotransmitter secretion GO:0007269 62 0.024
regulation of organelle organization GO:0033043 289 0.024
developmental growth involved in morphogenesis GO:0060560 138 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
gliogenesis GO:0042063 141 0.024
glycosyl compound metabolic process GO:1901657 246 0.023
ear development GO:0043583 200 0.023
central nervous system neuron differentiation GO:0021953 162 0.023
asymmetric neuroblast division GO:0055059 1 0.023
tube closure GO:0060606 91 0.023
regulation of ras protein signal transduction GO:0046578 114 0.023
ribonucleotide catabolic process GO:0009261 208 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
cation transport GO:0006812 399 0.023
germ cell development GO:0007281 185 0.023
cell type specific apoptotic process GO:0097285 268 0.023
renal system development GO:0072001 225 0.022
appendage morphogenesis GO:0035107 149 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
purine containing compound metabolic process GO:0072521 311 0.022
gtp catabolic process GO:0006184 143 0.022
regulation of kinase activity GO:0043549 249 0.022
regulation of smoothened signaling pathway GO:0008589 58 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
glial cell differentiation GO:0010001 131 0.021
modification dependent protein catabolic process GO:0019941 133 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
organelle localization GO:0051640 179 0.021
neurotransmitter transport GO:0006836 76 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.021
positive regulation of neuron differentiation GO:0045666 141 0.021
negative regulation of protein modification process GO:0031400 163 0.021
cellular protein catabolic process GO:0044257 155 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
regulation of secretion by cell GO:1903530 249 0.021
appendage development GO:0048736 166 0.021
cellular macromolecule catabolic process GO:0044265 206 0.021
regulation of secretion GO:0051046 274 0.020
embryonic epithelial tube formation GO:0001838 130 0.020
ion transmembrane transport GO:0034220 361 0.020
skeletal system development GO:0001501 356 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
epithelial tube formation GO:0072175 130 0.020
camera type eye development GO:0043010 266 0.020
positive regulation of protein modification process GO:0031401 299 0.020
regulation of protein kinase activity GO:0045859 232 0.020
negative regulation of phosphorylation GO:0042326 166 0.019
response to growth factor GO:0070848 198 0.019
cellular protein complex assembly GO:0043623 116 0.019
lung development GO:0030324 164 0.019
apoptotic signaling pathway GO:0097190 306 0.019
regulation of purine nucleotide catabolic process GO:0033121 122 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
regulation of canonical wnt signaling pathway GO:0060828 82 0.019
memory GO:0007613 58 0.019
positive regulation of programmed cell death GO:0043068 218 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
protein ubiquitination GO:0016567 171 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
regulation of muscle tissue development GO:1901861 97 0.018
regulation of feeding behavior GO:0060259 3 0.018
multicellular organismal signaling GO:0035637 91 0.018
regulation of cellular response to stress GO:0080135 159 0.018
respiratory system development GO:0060541 190 0.018
dorsal ventral axon guidance GO:0033563 3 0.017
nucleotide catabolic process GO:0009166 217 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.017
neural tube formation GO:0001841 108 0.017
neural tube development GO:0021915 160 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
regulation of cell activation GO:0050865 289 0.017
divalent metal ion transport GO:0070838 172 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
heterocycle catabolic process GO:0046700 280 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
organelle assembly GO:0070925 177 0.017
embryonic organ morphogenesis GO:0048562 276 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
neural precursor cell proliferation GO:0061351 121 0.016
respiratory tube development GO:0030323 167 0.016
neuron migration GO:0001764 122 0.016
divalent inorganic cation transport GO:0072511 178 0.016
regulation of proteolysis GO:0030162 164 0.016
regulation of cellular component size GO:0032535 121 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
plasma membrane organization GO:0007009 90 0.016
nucleoside catabolic process GO:0009164 206 0.016
regulation of cell cycle GO:0051726 281 0.016
regulation of epithelial cell proliferation GO:0050678 141 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
wound healing GO:0042060 157 0.016
compound eye development GO:0048749 1 0.016
metanephros development GO:0001656 79 0.016
myotube differentiation GO:0014902 105 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
lateral inhibition GO:0046331 1 0.016
establishment or maintenance of cell polarity GO:0007163 86 0.016
negative regulation of synapse assembly GO:0051964 3 0.016
regulation of neurotransmitter levels GO:0001505 87 0.016
mitotic cell cycle GO:0000278 195 0.016
regulation of neuron death GO:1901214 134 0.016
regulation of extent of cell growth GO:0061387 52 0.016
regulation of transferase activity GO:0051338 263 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.015
regulation of system process GO:0044057 200 0.015
forebrain development GO:0030900 302 0.015
asymmetric stem cell division GO:0098722 3 0.015
primary neural tube formation GO:0014020 95 0.015
skeletal muscle organ development GO:0060538 163 0.015
chromatin organization GO:0006325 206 0.015
cell fate commitment GO:0045165 210 0.015
peptidyl tyrosine phosphorylation GO:0018108 143 0.015
extracellular matrix organization GO:0030198 147 0.015
chromatin modification GO:0016568 187 0.015
negative regulation of transferase activity GO:0051348 85 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
sensory perception GO:0007600 245 0.015
cell substrate adhesion GO:0031589 130 0.014
negative regulation of cell cycle GO:0045786 123 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
rac protein signal transduction GO:0016601 13 0.014
metal ion homeostasis GO:0055065 189 0.014
histone modification GO:0016570 159 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
spermatogenesis GO:0007283 284 0.014
lateral line system development GO:0048925 1 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
nitrogen compound transport GO:0071705 271 0.014
morphogenesis of a branching epithelium GO:0061138 193 0.014
telencephalon development GO:0021537 186 0.014
ossification GO:0001503 216 0.014
intracellular protein transport GO:0006886 204 0.014
organelle fission GO:0048285 170 0.014
defecation GO:0030421 1 0.014
cation homeostasis GO:0055080 212 0.014
regulation of cell motility GO:2000145 236 0.014
dendrite development GO:0016358 115 0.014
neural tube closure GO:0001843 90 0.014
regulation of cell adhesion GO:0030155 154 0.014
male gamete generation GO:0048232 285 0.013
response to organonitrogen compound GO:0010243 246 0.013
neuron neuron synaptic transmission GO:0007270 69 0.013
regionalization GO:0003002 337 0.013
oxidation reduction process GO:0055114 342 0.013
dephosphorylation GO:0016311 129 0.013
gonad development GO:0008406 141 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
synaptic vesicle localization GO:0097479 59 0.013
limb development GO:0060173 166 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
cellular chemical homeostasis GO:0055082 215 0.013
establishment of vesicle localization GO:0051650 81 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
cell maturation GO:0048469 127 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
response to inorganic substance GO:0010035 96 0.013
fertilization GO:0009566 127 0.013
morphogenesis of a branching structure GO:0001763 203 0.013
actin cytoskeleton organization GO:0030036 220 0.013
regulation of homeostatic process GO:0032844 182 0.013
response to oxidative stress GO:0006979 123 0.013
peptide secretion GO:0002790 114 0.013
gtp metabolic process GO:0046039 144 0.013
fat cell differentiation GO:0045444 160 0.013
transmission of nerve impulse GO:0019226 76 0.013
cellular response to organonitrogen compound GO:0071417 145 0.012
protein polymerization GO:0051258 57 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
embryonic limb morphogenesis GO:0030326 126 0.012
extracellular structure organization GO:0043062 148 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.012
transmembrane transport GO:0055085 412 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
methylation GO:0032259 134 0.012
mesodermal cell migration GO:0008078 4 0.012
multi multicellular organism process GO:0044706 109 0.012
epithelial cell proliferation GO:0050673 174 0.012
actin filament organization GO:0007015 113 0.012
regulation of cell migration GO:0030334 219 0.012
neuron projection extension GO:1990138 64 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
amide transport GO:0042886 138 0.012
mitochondrion transport along microtubule GO:0047497 3 0.012
regulation of postsynaptic membrane potential GO:0060078 48 0.012
regulation of protein localization GO:0032880 231 0.012
sequestering of calcium ion GO:0051208 18 0.012
myeloid cell differentiation GO:0030099 233 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
organophosphate catabolic process GO:0046434 232 0.012
response to endoplasmic reticulum stress GO:0034976 53 0.012
regulation of axon extension GO:0030516 43 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
heart morphogenesis GO:0003007 178 0.012
regulation of interleukin 8 production GO:0032677 3 0.012
interleukin 8 production GO:0032637 4 0.012
rhythmic process GO:0048511 174 0.012
negative regulation of growth GO:0045926 99 0.012
positive regulation of proteolysis GO:0045862 85 0.012
protein localization to membrane GO:0072657 108 0.012
locomotory behavior GO:0007626 195 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
regulation of ras gtpase activity GO:0032318 88 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
regulation of ion transport GO:0043269 215 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
establishment of endothelial blood brain barrier GO:0014045 3 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
response to nutrient levels GO:0031667 109 0.011
regulation of striated muscle cell differentiation GO:0051153 81 0.011
mapk cascade GO:0000165 281 0.011
peptide transport GO:0015833 133 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
axon ensheathment GO:0008366 76 0.011
developmental maturation GO:0021700 193 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
regulation of protein catabolic process GO:0042176 108 0.011
retina development in camera type eye GO:0060041 119 0.011
lipid biosynthetic process GO:0008610 179 0.011
cytoplasmic transport GO:0016482 234 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
ear morphogenesis GO:0042471 118 0.011
negative regulation of kinase activity GO:0033673 81 0.011
covalent chromatin modification GO:0016569 163 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
response to radiation GO:0009314 165 0.011
nuclear division GO:0000280 158 0.011
multicellular organism growth GO:0035264 161 0.011
positive regulation of transferase activity GO:0051347 167 0.011
mitotic cytokinesis GO:0000281 4 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
negative regulation of cell migration GO:0030336 59 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
protein maturation GO:0051604 176 0.011
sodium ion transport GO:0006814 73 0.011
cytokine production GO:0001816 319 0.011
negative regulation of immune system process GO:0002683 209 0.011
striated muscle cell development GO:0055002 125 0.011
peptidyl tyrosine modification GO:0018212 145 0.010
purine ribonucleotide biosynthetic process GO:0009152 59 0.010
ameboidal type cell migration GO:0001667 128 0.010
maintenance of location GO:0051235 89 0.010
regulation of lipid metabolic process GO:0019216 118 0.010
regulation of rho gtpase activity GO:0032319 58 0.010
transition metal ion homeostasis GO:0055076 54 0.010
exocytosis GO:0006887 121 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
stem cell proliferation GO:0072089 117 0.010
protein targeting GO:0006605 143 0.010
positive regulation of interleukin 8 production GO:0032757 2 0.010
neuroblast proliferation GO:0007405 49 0.010
response to light stimulus GO:0009416 135 0.010
organ growth GO:0035265 117 0.010
negative regulation of neuron projection development GO:0010977 50 0.010
regulation of binding GO:0051098 111 0.010
gland development GO:0048732 330 0.010
skeletal system morphogenesis GO:0048705 203 0.010
synaptic vesicle transport GO:0048489 57 0.010
mrna metabolic process GO:0016071 84 0.010
epidermis development GO:0008544 187 0.010

Fbxl16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
central nervous system disease DOID:331 0 0.015
brain disease DOID:936 0 0.012