Mus musculus

18 known processes

Gp2

glycoprotein 2 (zymogen granule membrane)

(Aliases: 2310037I18Rik,MGC141315,AV060639)

Gp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of defense response GO:0031347 233 0.153
g protein coupled receptor signaling pathway GO:0007186 243 0.147
regulation of cellular amine metabolic process GO:0033238 20 0.082
immune response activating signal transduction GO:0002757 116 0.079
inflammatory response GO:0006954 244 0.076
cation transport GO:0006812 399 0.075
transmembrane transport GO:0055085 412 0.070
immune response regulating signaling pathway GO:0002764 125 0.067
activation of immune response GO:0002253 138 0.065
regulation of cytokine production GO:0001817 266 0.063
regulation of membrane potential GO:0042391 192 0.062
positive regulation of keratinocyte proliferation GO:0010838 4 0.059
action potential GO:0001508 78 0.053
regulation of epithelial cell proliferation GO:0050678 141 0.053
organic hydroxy compound transport GO:0015850 93 0.053
response to organonitrogen compound GO:0010243 246 0.053
positive regulation of innate immune response GO:0045089 80 0.053
cytokine production GO:0001816 319 0.052
peptidyl amino acid modification GO:0018193 336 0.052
amine metabolic process GO:0009308 45 0.052
multicellular organismal homeostasis GO:0048871 164 0.050
positive regulation of cytokine production GO:0001819 174 0.050
regulation of cellular amino acid metabolic process GO:0006521 5 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
negative regulation of molecular function GO:0044092 258 0.047
innate immune response GO:0045087 157 0.047
positive regulation of cellular amine metabolic process GO:0033240 5 0.047
cellular amine metabolic process GO:0044106 44 0.046
regulation of body fluid levels GO:0050878 162 0.046
negative regulation of keratinocyte differentiation GO:0045617 4 0.046
regulation of response to wounding GO:1903034 189 0.045
organic anion transport GO:0015711 137 0.044
cellular lipid metabolic process GO:0044255 323 0.044
cellular amino acid metabolic process GO:0006520 103 0.044
macromolecule catabolic process GO:0009057 281 0.044
skin development GO:0043588 220 0.044
sequestering of metal ion GO:0051238 19 0.044
negative regulation of defense response GO:0031348 77 0.043
positive regulation of defense response GO:0031349 124 0.043
regulation of cell activation GO:0050865 289 0.042
regulation of innate immune response GO:0045088 91 0.041
cellular ketone metabolic process GO:0042180 84 0.041
cytoplasmic transport GO:0016482 234 0.040
negative regulation of cell proliferation GO:0008285 296 0.040
myeloid leukocyte activation GO:0002274 83 0.039
cellular homeostasis GO:0019725 240 0.039
striated muscle contraction GO:0006941 45 0.039
heterocycle catabolic process GO:0046700 280 0.038
cation homeostasis GO:0055080 212 0.037
cation transmembrane transport GO:0098655 266 0.037
positive regulation of protein modification process GO:0031401 299 0.037
aromatic compound catabolic process GO:0019439 286 0.037
keratinocyte proliferation GO:0043616 21 0.037
leukocyte mediated immunity GO:0002443 174 0.036
myeloid leukocyte differentiation GO:0002573 119 0.036
positive regulation of secretion GO:0051047 130 0.036
epithelial cell proliferation GO:0050673 174 0.035
neuronal action potential GO:0019228 54 0.035
epidermis development GO:0008544 187 0.034
cell cell recognition GO:0009988 44 0.034
regulation of system process GO:0044057 200 0.034
epithelial tube morphogenesis GO:0060562 303 0.033
divalent inorganic cation transport GO:0072511 178 0.033
oxidation reduction process GO:0055114 342 0.033
fertilization GO:0009566 127 0.032
transmission of nerve impulse GO:0019226 76 0.032
defense response to bacterium GO:0042742 119 0.031
positive regulation of secretion by cell GO:1903532 114 0.031
anion transport GO:0006820 177 0.031
blood circulation GO:0008015 195 0.030
regulation of cellular ketone metabolic process GO:0010565 66 0.030
calcium ion homeostasis GO:0055074 127 0.030
regulation of protein localization GO:0032880 231 0.030
regulation of inflammatory response GO:0050727 147 0.030
sequestering of calcium ion GO:0051208 18 0.030
immune effector process GO:0002252 321 0.030
toll like receptor signaling pathway GO:0002224 38 0.029
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
positive regulation of response to wounding GO:1903036 66 0.029
ensheathment of neurons GO:0007272 76 0.029
wnt signaling pathway GO:0016055 188 0.028
cellular calcium ion homeostasis GO:0006874 119 0.028
amino acid transmembrane transport GO:0003333 37 0.028
nitrogen compound transport GO:0071705 271 0.028
cellular response to cytokine stimulus GO:0071345 189 0.028
nucleotide metabolic process GO:0009117 332 0.028
i kappab kinase nf kappab signaling GO:0007249 85 0.027
regulation of neuron differentiation GO:0045664 281 0.027
regulation of cytokine secretion GO:0050707 61 0.027
regulation of cell migration GO:0030334 219 0.027
camera type eye development GO:0043010 266 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
regulation of secretion by cell GO:1903530 249 0.026
cellular response to peptidoglycan GO:0071224 4 0.026
anatomical structure homeostasis GO:0060249 145 0.026
negative regulation of immune system process GO:0002683 209 0.025
regulation of anatomical structure size GO:0090066 178 0.025
divalent inorganic cation homeostasis GO:0072507 138 0.025
regulation of keratinocyte proliferation GO:0010837 15 0.025
feeding behavior GO:0007631 62 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
acetylcholine transport GO:0015870 2 0.025
regulation of tumor necrosis factor production GO:0032680 49 0.025
carboxylic acid transport GO:0046942 100 0.025
regulation of secretion GO:0051046 274 0.025
cellular ion homeostasis GO:0006873 165 0.024
humoral immune response GO:0006959 57 0.024
male gamete generation GO:0048232 285 0.024
detection of stimulus GO:0051606 84 0.024
multicellular organismal signaling GO:0035637 91 0.024
regulation of cell motility GO:2000145 236 0.024
locomotory behavior GO:0007626 195 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
mapk cascade GO:0000165 281 0.023
binding of sperm to zona pellucida GO:0007339 34 0.023
calcium ion transport GO:0006816 159 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
activation of innate immune response GO:0002218 56 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
t cell activation GO:0042110 289 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
wound healing GO:0042060 157 0.023
divalent metal ion transport GO:0070838 172 0.023
innate immune response activating signal transduction GO:0002758 50 0.022
second messenger mediated signaling GO:0019932 73 0.022
metal ion homeostasis GO:0055065 189 0.022
interleukin 12 secretion GO:0072610 3 0.022
protein catabolic process GO:0030163 221 0.022
positive regulation of cell death GO:0010942 224 0.022
protein maturation GO:0051604 176 0.022
tissue homeostasis GO:0001894 115 0.021
negative regulation of protein modification process GO:0031400 163 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
regulation of leukocyte proliferation GO:0070663 121 0.021
regulation of systemic arterial blood pressure GO:0003073 61 0.021
positive regulation of tumor necrosis factor production GO:0032760 30 0.021
mature dendritic cell differentiation GO:0097029 3 0.021
myelination GO:0042552 74 0.021
muscle tissue development GO:0060537 308 0.020
striated muscle tissue development GO:0014706 293 0.020
regulation of blood pressure GO:0008217 93 0.020
response to organic cyclic compound GO:0014070 198 0.020
skeletal system development GO:0001501 356 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
cellular metal ion homeostasis GO:0006875 151 0.020
positive regulation of kinase activity GO:0033674 155 0.020
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.020
hematopoietic progenitor cell differentiation GO:0002244 143 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
anion transmembrane transport GO:0098656 71 0.019
ion transmembrane transport GO:0034220 361 0.019
regulation of hydrolase activity GO:0051336 246 0.019
positive regulation of epithelial cell proliferation GO:0050679 68 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
protein secretion GO:0009306 111 0.019
myeloid cell differentiation GO:0030099 233 0.019
cytokine mediated signaling pathway GO:0019221 115 0.019
response to nutrient levels GO:0031667 109 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
cellular response to lipopolysaccharide GO:0071222 77 0.019
tumor necrosis factor production GO:0032640 50 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
leukocyte differentiation GO:0002521 342 0.019
response to inorganic substance GO:0010035 96 0.019
digestive system development GO:0055123 200 0.019
organic acid transport GO:0015849 101 0.019
ameboidal type cell migration GO:0001667 128 0.019
axon ensheathment GO:0008366 76 0.019
maintenance of location GO:0051235 89 0.019
digestion GO:0007586 40 0.019
cellular divalent inorganic cation homeostasis GO:0072503 127 0.018
intrinsic apoptotic signaling pathway GO:0097193 132 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
defense response to gram positive bacterium GO:0050830 50 0.018
regulation of organelle organization GO:0033043 289 0.018
cytosolic calcium ion homeostasis GO:0051480 70 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
regulation of feeding behavior GO:0060259 3 0.018
positive regulation of ion transport GO:0043270 65 0.018
regulation of ion transport GO:0043269 215 0.018
osteoclast differentiation GO:0030316 62 0.018
cellular response to molecule of bacterial origin GO:0071219 83 0.018
spermatogenesis GO:0007283 284 0.018
lymphocyte proliferation GO:0046651 164 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
regulation of macrophage activation GO:0043030 17 0.018
keratinocyte differentiation GO:0030216 48 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
apoptotic signaling pathway GO:0097190 306 0.017
cellular chemical homeostasis GO:0055082 215 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
regulation of cellular response to stress GO:0080135 159 0.017
cell recognition GO:0008037 83 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
response to oxidative stress GO:0006979 123 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
muscle system process GO:0003012 141 0.017
regulation of cytokine biosynthetic process GO:0042035 59 0.017
adult behavior GO:0030534 135 0.017
chemokine mediated signaling pathway GO:0070098 17 0.017
regulation of transferase activity GO:0051338 263 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
response to lipopolysaccharide GO:0032496 128 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
organic acid catabolic process GO:0016054 51 0.017
negative regulation of immune effector process GO:0002698 55 0.017
mitotic cell cycle GO:0000278 195 0.017
organelle assembly GO:0070925 177 0.017
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.016
positive regulation of t cell extravasation GO:2000409 2 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
fat cell differentiation GO:0045444 160 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
dna metabolic process GO:0006259 303 0.016
macrophage activation GO:0042116 27 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
amino acid transport GO:0006865 61 0.016
sensory organ morphogenesis GO:0090596 242 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
heart process GO:0003015 94 0.016
homeostasis of number of cells GO:0048872 210 0.016
protein ubiquitination GO:0016567 171 0.016
response to extracellular stimulus GO:0009991 127 0.016
pattern recognition receptor signaling pathway GO:0002221 47 0.016
cardiac muscle contraction GO:0060048 32 0.015
regulation of tube size GO:0035150 57 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
axonogenesis GO:0007409 274 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
regulation of hormone levels GO:0010817 211 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
negative regulation of cell development GO:0010721 169 0.015
cytokine metabolic process GO:0042107 71 0.015
regulation of action potential GO:0098900 4 0.015
regulation of multi organism process GO:0043900 111 0.015
forebrain development GO:0030900 302 0.015
endocytosis GO:0006897 168 0.015
carboxylic acid catabolic process GO:0046395 51 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
chromatin modification GO:0016568 187 0.015
regulation of ion homeostasis GO:2000021 64 0.015
Mouse
defense response to gram negative bacterium GO:0050829 28 0.015
small molecule catabolic process GO:0044282 71 0.015
defecation GO:0030421 1 0.015
hormone metabolic process GO:0042445 86 0.015
positive regulation of interferon alpha production GO:0032727 4 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
response to radiation GO:0009314 165 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
multicellular organism growth GO:0035264 161 0.015
cellular response to lipid GO:0071396 145 0.014
nucleoside catabolic process GO:0009164 206 0.014
muscle cell differentiation GO:0042692 261 0.014
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.014
norepinephrine transport GO:0015874 2 0.014
immunoglobulin transcytosis in epithelial cells GO:0002414 2 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
regulation of neuron projection development GO:0010975 169 0.014
nucleoside metabolic process GO:0009116 246 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
norepinephrine secretion GO:0048243 2 0.014
ossification GO:0001503 216 0.014
regulation of protein transport GO:0051223 163 0.014
regulation of proteolysis GO:0030162 164 0.014
negative regulation of sterol transport GO:0032372 4 0.014
regulation of protein secretion GO:0050708 82 0.014
limb development GO:0060173 166 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
positive regulation of cell activation GO:0050867 158 0.014
negative regulation of epidermal cell differentiation GO:0045605 7 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
endocrine process GO:0050886 39 0.014
single fertilization GO:0007338 82 0.014
protein localization to organelle GO:0033365 185 0.013
protein processing GO:0016485 163 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
regulation of kinase activity GO:0043549 249 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
visual perception GO:0007601 52 0.013
regulation of cell projection organization GO:0031344 206 0.013
muscle contraction GO:0006936 101 0.013
adaptive immune response GO:0002250 155 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
regulation of t cell activation GO:0050863 170 0.013
zymogen activation GO:0031638 41 0.013
negative regulation of response to wounding GO:1903035 77 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
regulation of immunological synapse formation GO:2000520 2 0.013
actin cytoskeleton organization GO:0030036 220 0.013
memory GO:0007613 58 0.013
l amino acid transport GO:0015807 32 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
negative regulation of macrophage apoptotic process GO:2000110 3 0.013
interleukin 18 production GO:0032621 4 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
lipid transport GO:0006869 98 0.013
regulation of binding GO:0051098 111 0.013
positive regulation of cytokine biosynthetic process GO:0042108 40 0.013
regulation of mapk cascade GO:0043408 248 0.013
positive regulation of monocyte chemotaxis GO:0090026 2 0.013
peptide metabolic process GO:0006518 46 0.013
lymphocyte differentiation GO:0030098 242 0.013
purine containing compound metabolic process GO:0072521 311 0.013
cellular response to external stimulus GO:0071496 88 0.013
chemotaxis GO:0006935 247 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
mitotic cell cycle process GO:1903047 159 0.012
multi organism behavior GO:0051705 62 0.012
exocytosis GO:0006887 121 0.012
angiogenesis GO:0001525 201 0.012
negative regulation of cell activation GO:0050866 111 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
positive regulation of interleukin 8 production GO:0032757 2 0.012
telencephalon development GO:0021537 186 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
l alpha amino acid transmembrane transport GO:1902475 23 0.012
cytokine secretion GO:0050663 72 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
monoamine transport GO:0015844 33 0.012
microtubule based process GO:0007017 236 0.012
positive regulation of transferase activity GO:0051347 167 0.012
positive regulation of catecholamine secretion GO:0033605 2 0.012
leukocyte migration GO:0050900 124 0.012
detection of molecule of bacterial origin GO:0032490 2 0.012
antigen processing and presentation GO:0019882 47 0.012
regulation of cell cycle GO:0051726 281 0.012
regulation of neurotransmitter levels GO:0001505 87 0.012
sensory perception of light stimulus GO:0050953 54 0.012
calcium mediated signaling GO:0019722 46 0.012
positive regulation of immune effector process GO:0002699 107 0.012
sterol transport GO:0015918 38 0.012
positive regulation of protein transport GO:0051222 93 0.012
blood vessel morphogenesis GO:0048514 285 0.012
germ cell development GO:0007281 185 0.012
regulation of monocyte chemotaxis GO:0090025 3 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
cytosolic calcium ion transport GO:0060401 48 0.012
cell junction organization GO:0034330 77 0.012
negative regulation of inflammatory response GO:0050728 61 0.012
intracellular protein transport GO:0006886 204 0.012
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.011
cell fate commitment GO:0045165 210 0.011
cellular protein catabolic process GO:0044257 155 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
skeletal muscle organ development GO:0060538 163 0.011
purine containing compound catabolic process GO:0072523 213 0.011
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.011
synaptic transmission GO:0007268 329 0.011
ras protein signal transduction GO:0007265 77 0.011
connective tissue development GO:0061448 179 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
hindbrain development GO:0030902 128 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
regulation of ph GO:0006885 26 0.011
gland development GO:0048732 330 0.011
intestinal epithelial structure maintenance GO:0060729 4 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
renal system development GO:0072001 225 0.011
Mouse
regulation of phospholipase a2 activity GO:0032429 3 0.011
interleukin 6 production GO:0032635 58 0.011
circulatory system process GO:0003013 197 0.011
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.011
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.011
placenta development GO:0001890 140 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
eosinophil activation GO:0043307 1 0.011
detection of external stimulus GO:0009581 61 0.011
regulation of circadian sleep wake cycle GO:0042749 3 0.011
cytokine biosynthetic process GO:0042089 68 0.011
b cell activation GO:0042113 161 0.011
chromatin organization GO:0006325 206 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
pallium development GO:0021543 120 0.011
regulation of interleukin 18 production GO:0032661 3 0.011
lateral inhibition GO:0046331 1 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
positive regulation of cell development GO:0010720 237 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
acetate ester transport GO:1901374 2 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
antigen receptor mediated signaling pathway GO:0050851 64 0.011
regulation of protein kinase activity GO:0045859 232 0.011
pharynx development GO:0060465 1 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
response to iron ion GO:0010039 4 0.010
sperm egg recognition GO:0035036 37 0.010
regulation of adaptive immune response GO:0002819 90 0.010
organelle localization GO:0051640 179 0.010
regulation of leukocyte mediated immunity GO:0002703 104 0.010
regulation of ossification GO:0030278 112 0.010
regulation of homeostatic process GO:0032844 182 0.010
Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
nucleotide catabolic process GO:0009166 217 0.010
sulfur compound metabolic process GO:0006790 100 0.010
adult locomotory behavior GO:0008344 91 0.010
t cell receptor signaling pathway GO:0050852 46 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
positive regulation of interleukin 18 production GO:0032741 2 0.010
cellular response to abiotic stimulus GO:0071214 56 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
protein targeting GO:0006605 143 0.010

Gp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.024
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
eye and adnexa disease DOID:1492 0 0.024
eye disease DOID:5614 0 0.019
organ system cancer DOID:0050686 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011
disease of metabolism DOID:0014667 0 0.011