Mus musculus

79 known processes

Spen

SPEN homolog, transcriptional regulator (Drosophila)

(Aliases: mKIAA0929,Mint)

Spen biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
internal protein amino acid acetylation GO:0006475 42 0.292
covalent chromatin modification GO:0016569 163 0.288
chromatin modification GO:0016568 187 0.209
histone h3 acetylation GO:0043966 14 0.193
chromatin organization GO:0006325 206 0.166
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.146
internal peptidyl lysine acetylation GO:0018393 42 0.136
positive regulation of dna templated transcription elongation GO:0032786 2 0.131
peptidyl lysine modification GO:0018205 77 0.116
histone acetylation GO:0016573 41 0.110
cell fate commitment GO:0045165 210 0.108
Fly
histone modification GO:0016570 159 0.099
embryonic organ morphogenesis GO:0048562 276 0.093
regulation of histone h3 k4 methylation GO:0051569 12 0.088
nucleoside metabolic process GO:0009116 246 0.085
regionalization GO:0003002 337 0.084
Fly
regulation of cell cycle GO:0051726 281 0.082
negative regulation of cell proliferation GO:0008285 296 0.074
peptidyl amino acid modification GO:0018193 336 0.073
protein acylation GO:0043543 64 0.072
cellular ketone metabolic process GO:0042180 84 0.070
regulation of histone methylation GO:0031060 30 0.067
neural precursor cell proliferation GO:0061351 121 0.065
peptidyl lysine acetylation GO:0018394 45 0.065
histone h4 k16 acetylation GO:0043984 3 0.062
stem cell proliferation GO:0072089 117 0.062
organic cyclic compound catabolic process GO:1901361 295 0.061
ribonucleoside triphosphate catabolic process GO:0009203 199 0.061
negative regulation of protein metabolic process GO:0051248 282 0.058
purine nucleotide metabolic process GO:0006163 302 0.057
nucleoside catabolic process GO:0009164 206 0.055
axonogenesis GO:0007409 274 0.055
Fly
purine nucleoside metabolic process GO:0042278 241 0.054
regulation of transcription during meiosis GO:0051037 1 0.054
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.051
Fly
respiratory tube development GO:0030323 167 0.050
methylation GO:0032259 134 0.049
purine ribonucleotide metabolic process GO:0009150 290 0.049
neuron projection guidance GO:0097485 141 0.048
Fly
regulation of histone modification GO:0031056 56 0.048
wnt signaling pathway GO:0016055 188 0.047
Fly
nucleotide catabolic process GO:0009166 217 0.046
protein methylation GO:0006479 81 0.043
heterocycle catabolic process GO:0046700 280 0.043
purine ribonucleoside metabolic process GO:0046128 241 0.043
microtubule based process GO:0007017 236 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.042
regulation of chromatin modification GO:1903308 57 0.042
histone lysine methylation GO:0034968 50 0.042
macromolecule methylation GO:0043414 120 0.041
leukocyte differentiation GO:0002521 342 0.041
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.041
purine nucleoside catabolic process GO:0006152 205 0.040
purine nucleoside triphosphate metabolic process GO:0009144 226 0.040
rho protein signal transduction GO:0007266 32 0.040
aromatic compound catabolic process GO:0019439 286 0.038
purine containing compound catabolic process GO:0072523 213 0.038
gonad development GO:0008406 141 0.037
lung development GO:0030324 164 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.037
regulation of organelle organization GO:0033043 289 0.037
protein alkylation GO:0008213 81 0.036
cellular lipid metabolic process GO:0044255 323 0.036
purine nucleotide catabolic process GO:0006195 211 0.036
negative regulation of molecular function GO:0044092 258 0.035
ribose phosphate metabolic process GO:0019693 291 0.035
ribonucleotide metabolic process GO:0009259 291 0.035
negative regulation of protein modification process GO:0031400 163 0.034
glycosyl compound metabolic process GO:1901657 246 0.034
lipid biosynthetic process GO:0008610 179 0.034
regulation of cellular catabolic process GO:0031329 242 0.034
regulation of mitotic cell cycle GO:0007346 126 0.033
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.033
purine ribonucleotide catabolic process GO:0009154 208 0.033
purine nucleoside triphosphate catabolic process GO:0009146 203 0.033
purine containing compound metabolic process GO:0072521 311 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.033
regulation of membrane potential GO:0042391 192 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
nucleoside triphosphate metabolic process GO:0009141 230 0.031
cellular homeostasis GO:0019725 240 0.030
regulation of binding GO:0051098 111 0.030
forebrain development GO:0030900 302 0.030
myotube differentiation GO:0014902 105 0.030
organonitrogen compound catabolic process GO:1901565 264 0.030
ribonucleoside metabolic process GO:0009119 245 0.029
carbohydrate derivative catabolic process GO:1901136 231 0.029
regulation of neuron differentiation GO:0045664 281 0.029
negative regulation of cellular protein metabolic process GO:0032269 247 0.029
monosaccharide metabolic process GO:0005996 106 0.029
lymphocyte differentiation GO:0030098 242 0.028
positive regulation of nucleoside metabolic process GO:0045979 91 0.028
cellular amino acid metabolic process GO:0006520 103 0.028
rhythmic process GO:0048511 174 0.027
nucleotide metabolic process GO:0009117 332 0.027
regulation of chromosome organization GO:0033044 83 0.027
male gamete generation GO:0048232 285 0.027
immune effector process GO:0002252 321 0.027
response to organonitrogen compound GO:0010243 246 0.027
dephosphorylation GO:0016311 129 0.027
cellular response to dna damage stimulus GO:0006974 207 0.026
regulation of cellular ketone metabolic process GO:0010565 66 0.026
lung alveolus development GO:0048286 45 0.026
histone methylation GO:0016571 71 0.026
guanosine containing compound metabolic process GO:1901068 144 0.026
histone h3 k4 trimethylation GO:0080182 5 0.026
positive regulation of neuron differentiation GO:0045666 141 0.026
hindbrain development GO:0030902 128 0.025
mitotic cell cycle process GO:1903047 159 0.025
regulation of cellular response to stress GO:0080135 159 0.025
regulation of cell cycle process GO:0010564 160 0.025
multicellular organismal signaling GO:0035637 91 0.025
protein catabolic process GO:0030163 221 0.024
ras protein signal transduction GO:0007265 77 0.024
ovarian follicle development GO:0001541 40 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
rna processing GO:0006396 105 0.023
stem cell differentiation GO:0048863 268 0.023
Fly
negative regulation of triglyceride metabolic process GO:0090209 4 0.023
skeletal system morphogenesis GO:0048705 203 0.023
asymmetric stem cell division GO:0098722 3 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
organophosphate catabolic process GO:0046434 232 0.022
cytoplasmic transport GO:0016482 234 0.022
transmission of nerve impulse GO:0019226 76 0.022
cation homeostasis GO:0055080 212 0.022
regulation of purine nucleotide catabolic process GO:0033121 122 0.022
microtubule cytoskeleton organization GO:0000226 157 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
camera type eye development GO:0043010 266 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
acylglycerol biosynthetic process GO:0046463 18 0.021
carbohydrate metabolic process GO:0005975 230 0.021
negative regulation of cell cycle process GO:0010948 69 0.021
skeletal system development GO:0001501 356 0.021
cellular macromolecule catabolic process GO:0044265 206 0.021
regulation of cell motility GO:2000145 236 0.021
anion transport GO:0006820 177 0.021
blood vessel morphogenesis GO:0048514 285 0.021
Mouse
positive regulation of nervous system development GO:0051962 221 0.021
Human
cellular response to organonitrogen compound GO:0071417 145 0.020
gtp catabolic process GO:0006184 143 0.020
second messenger mediated signaling GO:0019932 73 0.020
regulation of mrna processing GO:0050684 41 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.020
muscle tissue development GO:0060537 308 0.020
negative regulation of cell cycle GO:0045786 123 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
bone development GO:0060348 120 0.019
lens development in camera type eye GO:0002088 62 0.019
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
jak stat cascade GO:0007259 42 0.019
regulation of leukocyte differentiation GO:1902105 159 0.019
adult behavior GO:0030534 135 0.019
protein localization to organelle GO:0033365 185 0.019
spermatogenesis GO:0007283 284 0.019
striated muscle tissue development GO:0014706 293 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
sequestering of calcium ion GO:0051208 18 0.019
regulation of stem cell proliferation GO:0072091 78 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.019
compound eye development GO:0048749 1 0.019
Fly
cellular chemical homeostasis GO:0055082 215 0.019
protein localization to cell junction GO:1902414 3 0.019
macromolecule catabolic process GO:0009057 281 0.019
myeloid cell differentiation GO:0030099 233 0.019
Mouse
compartment pattern specification GO:0007386 4 0.018
mitotic cell cycle GO:0000278 195 0.018
gene silencing GO:0016458 38 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
chemotaxis GO:0006935 247 0.018
Fly
positive regulation of protein phosphorylation GO:0001934 242 0.018
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.018
homeostasis of number of cells GO:0048872 210 0.018
rna splicing GO:0008380 54 0.018
ear development GO:0043583 200 0.018
cellular amine metabolic process GO:0044106 44 0.018
development of primary female sexual characteristics GO:0046545 73 0.018
triglyceride biosynthetic process GO:0019432 17 0.018
organelle localization GO:0051640 179 0.018
development of primary sexual characteristics GO:0045137 143 0.018
endocytosis GO:0006897 168 0.017
telencephalon development GO:0021537 186 0.017
dna methylation GO:0006306 43 0.017
negative regulation of triglyceride biosynthetic process GO:0010868 2 0.017
locomotory behavior GO:0007626 195 0.017
transmembrane transport GO:0055085 412 0.017
nuclear division GO:0000280 158 0.017
ribonucleoside monophosphate metabolic process GO:0009161 80 0.017
germ cell development GO:0007281 185 0.017
protein autophosphorylation GO:0046777 61 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
cellular ion homeostasis GO:0006873 165 0.017
axon guidance GO:0007411 141 0.017
Fly
amine metabolic process GO:0009308 45 0.016
dna alkylation GO:0006305 43 0.016
mapk cascade GO:0000165 281 0.016
sensory organ morphogenesis GO:0090596 242 0.016
exocytosis GO:0006887 121 0.016
regulation of secretion by cell GO:1903530 249 0.016
atp metabolic process GO:0046034 75 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
Fly
protein modification by small protein conjugation GO:0032446 187 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
carboxylic acid biosynthetic process GO:0046394 86 0.016
mrna metabolic process GO:0016071 84 0.016
organelle fission GO:0048285 170 0.016
response to molecule of bacterial origin GO:0002237 143 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
regulation of rho protein signal transduction GO:0035023 71 0.016
histone h4 k12 acetylation GO:0043983 2 0.016
regulation of protein localization GO:0032880 231 0.016
asymmetric neuroblast division GO:0055059 1 0.016
circadian rhythm GO:0007623 114 0.016
cartilage development GO:0051216 140 0.016
histone h4 acetylation GO:0043967 10 0.016
response to peptide hormone GO:0043434 127 0.016
sensory perception GO:0007600 245 0.016
regulation of response to drug GO:2001023 2 0.016
cell adhesion GO:0007155 329 0.016
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.015
positive regulation of neuron projection development GO:0010976 79 0.015
inflammatory response GO:0006954 244 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.015
circulatory system process GO:0003013 197 0.015
negative regulation of homeostatic process GO:0032845 71 0.015
positive regulation of cell projection organization GO:0031346 95 0.015
metal ion homeostasis GO:0055065 189 0.015
positive regulation of mapk cascade GO:0043410 170 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.015
epithelial cell development GO:0002064 159 0.015
cardiac muscle cell differentiation GO:0055007 69 0.015
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.015
response to organic cyclic compound GO:0014070 198 0.015
synaptic transmission GO:0007268 329 0.015
nitrogen compound transport GO:0071705 271 0.015
sequestering of metal ion GO:0051238 19 0.015
dna modification GO:0006304 50 0.015
blastocyst development GO:0001824 80 0.015
stem cell development GO:0048864 219 0.015
regulation of homeostatic process GO:0032844 182 0.015
gtp metabolic process GO:0046039 144 0.015
negative regulation of cell cycle phase transition GO:1901988 48 0.015
positive regulation of binding GO:0051099 49 0.015
cation transport GO:0006812 399 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
peptidyl lysine trimethylation GO:0018023 12 0.015
positive regulation of cell migration GO:0030335 109 0.014
histone h3 k14 acetylation GO:0044154 3 0.014
cellular response to peptide hormone stimulus GO:0071375 92 0.014
blastocyst growth GO:0001832 23 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
establishment of organelle localization GO:0051656 122 0.014
regulation of mapk cascade GO:0043408 248 0.014
single organismal cell cell adhesion GO:0016337 131 0.014
connective tissue development GO:0061448 179 0.014
appendage morphogenesis GO:0035107 149 0.014
Fly
proteasomal protein catabolic process GO:0010498 98 0.014
ameboidal type cell migration GO:0001667 128 0.014
sensory perception of mechanical stimulus GO:0050954 107 0.014
neuron migration GO:0001764 122 0.014
regulation of protein processing GO:0070613 96 0.014
regulation of cellular amino acid metabolic process GO:0006521 5 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
purine nucleoside monophosphate catabolic process GO:0009128 58 0.014
action potential GO:0001508 78 0.014
negative regulation of protein maturation GO:1903318 79 0.014
response to peptide GO:1901652 136 0.014
regulation of chromatin organization GO:1902275 57 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
regulation of lymphocyte anergy GO:0002911 4 0.014
cellular response to ethanol GO:0071361 3 0.014
stress activated mapk cascade GO:0051403 80 0.013
negative regulation of platelet derived growth factor receptor alpha signaling pathway GO:2000584 2 0.013
fat cell differentiation GO:0045444 160 0.013
regulation of fibroblast proliferation GO:0048145 34 0.013
regulation of hydrolase activity GO:0051336 246 0.013
regulation of mrna splicing via spliceosome GO:0048024 32 0.013
cellularization GO:0007349 1 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
defecation GO:0030421 1 0.013
organic acid biosynthetic process GO:0016053 86 0.013
male meiosis i GO:0007141 16 0.013
neuroblast differentiation GO:0014016 2 0.013
Fly
t cell differentiation GO:0030217 174 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
nucleoside monophosphate catabolic process GO:0009125 59 0.013
organ growth GO:0035265 117 0.013
translation GO:0006412 93 0.013
gland development GO:0048732 330 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
carbohydrate homeostasis GO:0033500 128 0.013
memory GO:0007613 58 0.013
embryonic hemopoiesis GO:0035162 23 0.013
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.013
male meiosis GO:0007140 37 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
kidney development GO:0001822 213 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
negative regulation of immune system process GO:0002683 209 0.013
Mouse
response to insulin GO:0032868 100 0.013
neutral lipid biosynthetic process GO:0046460 18 0.013
g1 s transition of mitotic cell cycle GO:0000082 57 0.012
hexose biosynthetic process GO:0019319 39 0.012
regulation of lipid biosynthetic process GO:0046890 54 0.012
female sex differentiation GO:0046660 84 0.012
regulation of secretion GO:0051046 274 0.012
regulation of transferase activity GO:0051338 263 0.012
regulation of triglyceride biosynthetic process GO:0010866 10 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
respiratory system development GO:0060541 190 0.012
renal system development GO:0072001 225 0.012
neuronal action potential GO:0019228 54 0.012
ribonucleoside monophosphate catabolic process GO:0009158 57 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
regulation of mrna metabolic process GO:1903311 43 0.012
cellular protein catabolic process GO:0044257 155 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
neuroblast fate commitment GO:0014017 1 0.012
Fly
spermatid differentiation GO:0048515 115 0.012
regulation of neuron projection development GO:0010975 169 0.012
regulation of dna binding GO:0051101 39 0.012
regulation of intracellular transport GO:0032386 159 0.012
embryonic genitalia morphogenesis GO:0030538 4 0.012
carbohydrate biosynthetic process GO:0016051 74 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
t cell activation GO:0042110 289 0.012
cardiac muscle tissue development GO:0048738 130 0.012
regulation of cell projection organization GO:0031344 206 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
mrna processing GO:0006397 63 0.012
female gamete generation GO:0007292 74 0.012
rna interference GO:0016246 2 0.012
regulation of striated muscle cell differentiation GO:0051153 81 0.012
small molecule biosynthetic process GO:0044283 132 0.012
histone h3 k4 methylation GO:0051568 23 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
regulation of protein binding GO:0043393 60 0.012
regulation of fat cell differentiation GO:0045598 81 0.012
positive regulation of protein modification process GO:0031401 299 0.012
cellular response to hormone stimulus GO:0032870 150 0.011
regulation of protein maturation GO:1903317 96 0.011
regulation of translation GO:0006417 71 0.011
muscle system process GO:0003012 141 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.011
cell division GO:0051301 120 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
Mouse
regulation of cell activation GO:0050865 289 0.011
peptide transport GO:0015833 133 0.011
limb morphogenesis GO:0035108 149 0.011
alpha beta t cell differentiation GO:0046632 69 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
primary neural tube formation GO:0014020 95 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
nuclear transport GO:0051169 139 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
monosaccharide biosynthetic process GO:0046364 44 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
glucose homeostasis GO:0042593 128 0.011
regulation of cell adhesion GO:0030155 154 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
positive regulation of cell development GO:0010720 237 0.011
Human
gliogenesis GO:0042063 141 0.011
Fly
response to radiation GO:0009314 165 0.011
intracellular protein transport GO:0006886 204 0.011
inner cell mass cell proliferation GO:0001833 15 0.011
regulation of system process GO:0044057 200 0.011
epithalamus development GO:0021538 2 0.011
limb development GO:0060173 166 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
cytokine production GO:0001816 319 0.011
digestive tract development GO:0048565 190 0.011
actin filament organization GO:0007015 113 0.011
neuroblast proliferation GO:0007405 49 0.011
cell proliferation in forebrain GO:0021846 30 0.011
cell type specific apoptotic process GO:0097285 268 0.011
negative regulation of cell development GO:0010721 169 0.011
establishment of planar polarity GO:0001736 28 0.011
Fly
glycerolipid biosynthetic process GO:0045017 50 0.011
regulation of response to wounding GO:1903034 189 0.011
mitotic cytokinesis GO:0000281 4 0.011
heart morphogenesis GO:0003007 178 0.011
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.011
smoothened signaling pathway GO:0007224 105 0.011
regulation of ion transport GO:0043269 215 0.011
urogenital system development GO:0001655 261 0.011
glycerolipid metabolic process GO:0046486 122 0.010
regulation of stress activated mapk cascade GO:0032872 69 0.010
monocarboxylic acid biosynthetic process GO:0072330 61 0.010
response to extracellular stimulus GO:0009991 127 0.010
calcium ion homeostasis GO:0055074 127 0.010
protein localization to nucleus GO:0034504 121 0.010
dna metabolic process GO:0006259 303 0.010
chromatin remodeling GO:0006338 32 0.010
regulation of extent of cell growth GO:0061387 52 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.010
appendage development GO:0048736 166 0.010
Fly
ion transmembrane transport GO:0034220 361 0.010
regulation of hippo signaling GO:0035330 1 0.010
negative regulation of organelle organization GO:0010639 90 0.010
smad protein signal transduction GO:0060395 21 0.010
i kappab kinase nf kappab signaling GO:0007249 85 0.010
regulation of cell migration GO:0030334 219 0.010
response to light stimulus GO:0009416 135 0.010
regulation of rna splicing GO:0043484 37 0.010
multi multicellular organism process GO:0044706 109 0.010
regulation of lamellipodium assembly GO:0010591 3 0.010
small gtpase mediated signal transduction GO:0007264 97 0.010
muscle cell differentiation GO:0042692 261 0.010
oocyte axis specification GO:0007309 2 0.010
organic anion transport GO:0015711 137 0.010
spleen development GO:0048536 39 0.010
Mouse

Spen disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.041
disease of mental health DOID:150 0 0.014
musculoskeletal system disease DOID:17 0 0.013
immune system disease DOID:2914 0 0.013
hematopoietic system disease DOID:74 0 0.013
immune system cancer DOID:0060083 0 0.012
hematologic cancer DOID:2531 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
central nervous system disease DOID:331 0 0.011
neurodegenerative disease DOID:1289 0 0.011