Mus musculus

13 known processes

Defb6

defensin beta 6

(Aliases: BD-6)

Defb6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.346
inorganic ion transmembrane transport GO:0098660 234 0.167
transmembrane transport GO:0055085 412 0.148
regulation of membrane potential GO:0042391 192 0.105
inorganic cation transmembrane transport GO:0098662 207 0.095
cation transmembrane transport GO:0098655 266 0.081
positive regulation of cellular amine metabolic process GO:0033240 5 0.075
leukocyte differentiation GO:0002521 342 0.074
organic cyclic compound catabolic process GO:1901361 295 0.070
regulation of muscle tissue development GO:1901861 97 0.068
membrane organization GO:0061024 245 0.066
regulation of cytokine production GO:0001817 266 0.056
cellular amino acid metabolic process GO:0006520 103 0.055
response to molecule of bacterial origin GO:0002237 143 0.055
cation homeostasis GO:0055080 212 0.055
regulation of renin secretion into blood stream GO:1900133 4 0.054
regulation of protein transport GO:0051223 163 0.052
regulation of protein localization GO:0032880 231 0.052
hematopoietic progenitor cell differentiation GO:0002244 143 0.052
metal ion homeostasis GO:0055065 189 0.051
positive regulation of eosinophil migration GO:2000418 2 0.050
cellular ion homeostasis GO:0006873 165 0.050
intermediate filament based process GO:0045103 27 0.049
cellular response to organonitrogen compound GO:0071417 145 0.049
skin development GO:0043588 220 0.049
regulation of body fluid levels GO:0050878 162 0.049
response to organonitrogen compound GO:0010243 246 0.048
cellular homeostasis GO:0019725 240 0.048
cellular ketone metabolic process GO:0042180 84 0.048
cellular response to cytokine stimulus GO:0071345 189 0.048
regulation of hydrolase activity GO:0051336 246 0.046
regulation of secretion GO:0051046 274 0.045
cell type specific apoptotic process GO:0097285 268 0.044
developmental maturation GO:0021700 193 0.041
regulation of cell activation GO:0050865 289 0.040
macromolecule catabolic process GO:0009057 281 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
regulation of secretion by cell GO:1903530 249 0.038
organic hydroxy compound metabolic process GO:1901615 203 0.038
positive regulation of protein modification process GO:0031401 299 0.038
cellular lipid metabolic process GO:0044255 323 0.038
regulation of epithelial cell proliferation GO:0050678 141 0.037
amine metabolic process GO:0009308 45 0.037
purine nucleotide metabolic process GO:0006163 302 0.037
protein processing GO:0016485 163 0.037
cellular amine metabolic process GO:0044106 44 0.037
regulation of cellular ketone metabolic process GO:0010565 66 0.036
g protein coupled receptor signaling pathway GO:0007186 243 0.036
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.035
regulation of hormone levels GO:0010817 211 0.035
positive regulation of cytokine production GO:0001819 174 0.034
detection of abiotic stimulus GO:0009582 60 0.034
cellular chemical homeostasis GO:0055082 215 0.034
sensory perception GO:0007600 245 0.033
innate immune response GO:0045087 157 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
regulation of defense response GO:0031347 233 0.033
extrinsic apoptotic signaling pathway GO:0097191 126 0.031
t cell activation GO:0042110 289 0.031
regulation of transmembrane transport GO:0034762 128 0.031
regulation of protein kinase activity GO:0045859 232 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.030
cytokine production GO:0001816 319 0.030
apoptotic signaling pathway GO:0097190 306 0.030
negative regulation of molecular function GO:0044092 258 0.030
regulation of systemic arterial blood pressure GO:0003073 61 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.029
nucleotide catabolic process GO:0009166 217 0.029
homeostasis of number of cells GO:0048872 210 0.029
regulation of transferase activity GO:0051338 263 0.029
lymphocyte differentiation GO:0030098 242 0.029
cation transport GO:0006812 399 0.029
cytoplasmic transport GO:0016482 234 0.029
response to lipopolysaccharide GO:0032496 128 0.028
purine nucleoside catabolic process GO:0006152 205 0.028
sequestering of metal ion GO:0051238 19 0.028
leukocyte mediated immunity GO:0002443 174 0.028
regulation of cell migration GO:0030334 219 0.027
small gtpase mediated signal transduction GO:0007264 97 0.026
inorganic anion transport GO:0015698 43 0.026
nitrogen compound transport GO:0071705 271 0.026
regulation of lymphocyte activation GO:0051249 240 0.026
regulation of t cell differentiation GO:0045580 83 0.026
regulation of ion transport GO:0043269 215 0.026
regulation of action potential GO:0098900 4 0.026
myoblast differentiation GO:0045445 52 0.025
epithelial cell development GO:0002064 159 0.025
aromatic compound catabolic process GO:0019439 286 0.025
divalent inorganic cation transport GO:0072511 178 0.025
positive regulation of immune effector process GO:0002699 107 0.025
regulation of response to wounding GO:1903034 189 0.024
divalent metal ion transport GO:0070838 172 0.024
neuronal action potential GO:0019228 54 0.024
regulation of kinase activity GO:0043549 249 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
spermatogenesis GO:0007283 284 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
skeletal muscle fiber development GO:0048741 58 0.023
regulation of blood pressure GO:0008217 93 0.023
single fertilization GO:0007338 82 0.023
exocytosis GO:0006887 121 0.023
positive regulation of ion transport GO:0043270 65 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
sequestering of calcium ion GO:0051208 18 0.023
divalent inorganic cation homeostasis GO:0072507 138 0.023
neutral lipid metabolic process GO:0006638 57 0.023
regulation of striated muscle cell differentiation GO:0051153 81 0.022
response to light stimulus GO:0009416 135 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
organic hydroxy compound transport GO:0015850 93 0.022
immune effector process GO:0002252 321 0.022
response to drug GO:0042493 75 0.022
regulation of ion homeostasis GO:2000021 64 0.022
epidermis development GO:0008544 187 0.022
rho protein signal transduction GO:0007266 32 0.022
response to organic cyclic compound GO:0014070 198 0.022
detection of stimulus GO:0051606 84 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
lymphocyte proliferation GO:0046651 164 0.021
positive regulation of protein transport GO:0051222 93 0.021
transepithelial chloride transport GO:0030321 4 0.021
cytokine mediated signaling pathway GO:0019221 115 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
regulation of t cell activation GO:0050863 170 0.021
calcium ion transport GO:0006816 159 0.021
epithelial cell proliferation GO:0050673 174 0.021
regulation of establishment of protein localization GO:0070201 181 0.021
transmission of nerve impulse GO:0019226 76 0.020
endocrine process GO:0050886 39 0.020
regulation of protein secretion GO:0050708 82 0.020
wound healing GO:0042060 157 0.020
regulation of metal ion transport GO:0010959 106 0.020
cellular calcium ion homeostasis GO:0006874 119 0.020
response to inorganic substance GO:0010035 96 0.020
atrial ventricular junction remodeling GO:0003294 2 0.020
nucleotide metabolic process GO:0009117 332 0.020
protein secretion GO:0009306 111 0.020
myotube cell development GO:0014904 60 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
protein oligomerization GO:0051259 67 0.019
inflammatory response GO:0006954 244 0.019
positive regulation of transferase activity GO:0051347 167 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
hormone metabolic process GO:0042445 86 0.019
purine containing compound metabolic process GO:0072521 311 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
defense response to bacterium GO:0042742 119 0.019
male gamete generation GO:0048232 285 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
regulation of ketone biosynthetic process GO:0010566 2 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
regulation of thyroid hormone generation GO:2000609 4 0.019
muscle fiber development GO:0048747 76 0.019
detection of external stimulus GO:0009581 61 0.019
cell communication by chemical coupling GO:0010643 2 0.018
purine containing compound catabolic process GO:0072523 213 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
anion transport GO:0006820 177 0.018
calcium ion homeostasis GO:0055074 127 0.018
positive regulation of secretion GO:0051047 130 0.018
cellular response to lipopolysaccharide GO:0071222 77 0.018
myeloid leukocyte differentiation GO:0002573 119 0.018
mapk cascade GO:0000165 281 0.018
regulation of homeostatic process GO:0032844 182 0.018
regulation of endocytosis GO:0030100 69 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.018
sa node cell action potential GO:0086015 4 0.018
ras protein signal transduction GO:0007265 77 0.018
cell differentiation involved in embryonic placenta development GO:0060706 26 0.018
axon ensheathment GO:0008366 76 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
protein catabolic process GO:0030163 221 0.018
sodium ion transmembrane transport GO:0035725 49 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
cell cell recognition GO:0009988 44 0.017
organophosphate catabolic process GO:0046434 232 0.017
blood circulation GO:0008015 195 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
chloride transport GO:0006821 32 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
response to tumor necrosis factor GO:0034612 26 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
actin filament based movement GO:0030048 23 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
striated muscle contraction GO:0006941 45 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
regulation of inflammatory response GO:0050727 147 0.016
leukocyte activation involved in immune response GO:0002366 126 0.016
detection of stimulus involved in sensory perception GO:0050906 44 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
nucleoside catabolic process GO:0009164 206 0.016
positive regulation of leukocyte differentiation GO:1902107 86 0.016
hair cycle GO:0042633 90 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
regulation of proteolysis GO:0030162 164 0.016
regulation of skeletal muscle fiber development GO:0048742 36 0.016
regulation of peptidase activity GO:0052547 96 0.016
regulation of neuron death GO:1901214 134 0.016
cell maturation GO:0048469 127 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
heterocycle catabolic process GO:0046700 280 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
sensory perception of sound GO:0007605 97 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
dephosphorylation GO:0016311 129 0.015
muscle cell differentiation GO:0042692 261 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
cofactor transport GO:0051181 4 0.015
leukocyte proliferation GO:0070661 172 0.015
ossification GO:0001503 216 0.015
negative regulation of cell motility GO:2000146 61 0.015
negative regulation of defense response GO:0031348 77 0.014
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.014
dna metabolic process GO:0006259 303 0.014
lipid catabolic process GO:0016042 69 0.014
placenta development GO:0001890 140 0.014
defense response to other organism GO:0098542 197 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
positive regulation of leukocyte mediated immunity GO:0002705 70 0.014
coagulation GO:0050817 78 0.014
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.014
tissue regeneration GO:0042246 22 0.014
cell chemotaxis GO:0060326 81 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
regulation of leukocyte apoptotic process GO:2000106 56 0.013
cell adhesion GO:0007155 329 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
blood vessel morphogenesis GO:0048514 285 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
regulation of leukocyte mediated immunity GO:0002703 104 0.013
cellular potassium ion transport GO:0071804 43 0.013
regulation of mapk cascade GO:0043408 248 0.013
cytosolic calcium ion homeostasis GO:0051480 70 0.013
response to amino acid GO:0043200 37 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
positive regulation of secretion by cell GO:1903532 114 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
cardiac muscle cell contraction GO:0086003 7 0.013
regulation of system process GO:0044057 200 0.013
insemination GO:0007320 6 0.013
cardiac muscle contraction GO:0060048 32 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
regulation of gtp catabolic process GO:0033124 113 0.013
regulation of protein processing GO:0070613 96 0.012
regulation of cell cycle GO:0051726 281 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
protein maturation GO:0051604 176 0.012
cell killing GO:0001906 67 0.012
response to peptide GO:1901652 136 0.012
regulation of epidermal cell differentiation GO:0045604 21 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
neuron apoptotic process GO:0051402 142 0.012
intermediate filament cytoskeleton organization GO:0045104 26 0.012
establishment of skin barrier GO:0061436 14 0.012
positive regulation of interleukin 6 production GO:0032755 37 0.012
peptidyl amino acid modification GO:0018193 336 0.012
regulation of ossification GO:0030278 112 0.012
multi multicellular organism process GO:0044706 109 0.012
embryonic placenta development GO:0001892 98 0.012
cellular lipid catabolic process GO:0044242 52 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.012
anion transmembrane transport GO:0098656 71 0.012
fatty acid metabolic process GO:0006631 121 0.012
maintenance of location GO:0051235 89 0.012
action potential GO:0001508 78 0.012
multicellular organismal signaling GO:0035637 91 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
sterol metabolic process GO:0016125 58 0.012
response to vitamin d GO:0033280 3 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.012
adaptive immune response GO:0002250 155 0.012
tissue remodeling GO:0048771 102 0.011
alcohol metabolic process GO:0006066 116 0.011
nucleoside metabolic process GO:0009116 246 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
sensory perception of chemical stimulus GO:0007606 51 0.011
heart process GO:0003015 94 0.011
compound eye development GO:0048749 1 0.011
circulatory system process GO:0003013 197 0.011
organ growth GO:0035265 117 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
release of sequestered calcium ion into cytosol GO:0051209 42 0.011
leukocyte migration GO:0050900 124 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
response to peptide hormone GO:0043434 127 0.011
carbohydrate transport GO:0008643 62 0.011
cellular response to lipid GO:0071396 145 0.011
leukocyte apoptotic process GO:0071887 71 0.011
chemotaxis GO:0006935 247 0.011
molting cycle GO:0042303 90 0.011
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.011
regulation of neuron differentiation GO:0045664 281 0.011
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.011
regulation of myotube differentiation GO:0010830 62 0.011
otic placode formation GO:0043049 1 0.011
cytosolic calcium ion transport GO:0060401 48 0.011
positive regulation of thymocyte migration GO:2000412 2 0.011
fertilization GO:0009566 127 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
granulocyte migration GO:0097530 43 0.011
renal system process GO:0003014 48 0.011
regeneration GO:0031099 38 0.011
regulation of epidermis development GO:0045682 33 0.011
ventricular cardiac muscle cell action potential GO:0086005 4 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
negative regulation of muscle cell differentiation GO:0051148 33 0.011
interleukin 8 production GO:0032637 4 0.011
cellularization GO:0007349 1 0.010
single organism cell adhesion GO:0098602 156 0.010
t cell mediated immunity GO:0002456 50 0.010
leukocyte mediated cytotoxicity GO:0001909 62 0.010
regulation of protein catabolic process GO:0042176 108 0.010
regulation of water loss via skin GO:0033561 16 0.010
sensory perception of mechanical stimulus GO:0050954 107 0.010
angiogenesis GO:0001525 201 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010
striated muscle tissue development GO:0014706 293 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.010
t cell differentiation GO:0030217 174 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
positive regulation of cell migration GO:0030335 109 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
negative regulation of response to wounding GO:1903035 77 0.010
negative regulation of phosphorus metabolic process GO:0010563 184 0.010
leukocyte chemotaxis GO:0030595 69 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.010
regulation of cell projection organization GO:0031344 206 0.010
calcium ion transport into cytosol GO:0060402 48 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.010

Defb6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.017
disease of anatomical entity DOID:7 0 0.017
disease of metabolism DOID:0014667 0 0.013
musculoskeletal system disease DOID:17 0 0.013
bone disease DOID:0080001 0 0.013
connective tissue disease DOID:65 0 0.013
inherited metabolic disorder DOID:655 0 0.011