Mus musculus

0 known processes

Defb4

defensin beta 4

(Aliases: BD-4,2310001F05Rik)

Defb4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
spermatogenesis GO:0007283 284 0.125
defense response to other organism GO:0098542 197 0.108
Mouse
defense response to bacterium GO:0042742 119 0.106
Mouse
male gamete generation GO:0048232 285 0.074
hematopoietic progenitor cell differentiation GO:0002244 143 0.062
developmental maturation GO:0021700 193 0.059
cellular response to cytokine stimulus GO:0071345 189 0.058
cation transport GO:0006812 399 0.056
glycoprotein metabolic process GO:0009100 116 0.053
dna metabolic process GO:0006259 303 0.051
epidermis development GO:0008544 187 0.051
regulation of cell cycle GO:0051726 281 0.051
regulation of t cell activation GO:0050863 170 0.050
striated muscle tissue development GO:0014706 293 0.049
cellular macromolecule catabolic process GO:0044265 206 0.045
cell adhesion GO:0007155 329 0.045
negative regulation of cellular protein metabolic process GO:0032269 247 0.043
leukocyte differentiation GO:0002521 342 0.042
regulation of leukocyte differentiation GO:1902105 159 0.039
sulfur compound metabolic process GO:0006790 100 0.039
cellular amino acid metabolic process GO:0006520 103 0.039
macromolecule catabolic process GO:0009057 281 0.037
regulation of blood pressure GO:0008217 93 0.037
cellular amine metabolic process GO:0044106 44 0.037
transmembrane transport GO:0055085 412 0.036
regulation of protein localization GO:0032880 231 0.036
negative regulation of molecular function GO:0044092 258 0.035
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
apoptotic signaling pathway GO:0097190 306 0.034
innate immune response GO:0045087 157 0.034
amine metabolic process GO:0009308 45 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.032
cell recognition GO:0008037 83 0.032
regulation of lymphocyte activation GO:0051249 240 0.032
skin development GO:0043588 220 0.031
protein catabolic process GO:0030163 221 0.031
leukocyte mediated immunity GO:0002443 174 0.030
sequestering of calcium ion GO:0051208 18 0.030
heterocycle catabolic process GO:0046700 280 0.030
myeloid cell differentiation GO:0030099 233 0.029
regulation of system process GO:0044057 200 0.029
nuclear division GO:0000280 158 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
posttranscriptional regulation of gene expression GO:0010608 155 0.028
regulation of t cell proliferation GO:0042129 92 0.027
lymphocyte mediated immunity GO:0002449 139 0.027
germ cell development GO:0007281 185 0.026
glycoprotein biosynthetic process GO:0009101 89 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.026
cell maturation GO:0048469 127 0.025
cellular ketone metabolic process GO:0042180 84 0.025
fertilization GO:0009566 127 0.025
muscle cell differentiation GO:0042692 261 0.025
aromatic compound catabolic process GO:0019439 286 0.025
regulation of protein transport GO:0051223 163 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
regulation of transferase activity GO:0051338 263 0.024
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.024
adaptive immune response GO:0002250 155 0.024
neural tube development GO:0021915 160 0.023
regulation of cytokine production GO:0001817 266 0.023
regulation of kinase activity GO:0043549 249 0.023
t cell activation GO:0042110 289 0.023
regulation of muscle tissue development GO:1901861 97 0.023
potassium ion transport GO:0006813 52 0.023
regulation of skeletal muscle fiber development GO:0048742 36 0.022
muscle tissue development GO:0060537 308 0.022
cellular lipid metabolic process GO:0044255 323 0.022
organic cyclic compound catabolic process GO:1901361 295 0.021
striated muscle cell development GO:0055002 125 0.021
positive regulation of nervous system development GO:0051962 221 0.021
fatty acid metabolic process GO:0006631 121 0.021
peptidyl amino acid modification GO:0018193 336 0.021
sensory perception of mechanical stimulus GO:0050954 107 0.021
t cell proliferation GO:0042098 120 0.021
negative regulation of cell proliferation GO:0008285 296 0.020
spermatid differentiation GO:0048515 115 0.020
cellular alcohol metabolic process GO:0044107 3 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
positive regulation of protein modification process GO:0031401 299 0.020
blood circulation GO:0008015 195 0.020
protein secretion GO:0009306 111 0.020
negative regulation of immune system process GO:0002683 209 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
cell type specific apoptotic process GO:0097285 268 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
positive regulation of transferase activity GO:0051347 167 0.020
leukocyte proliferation GO:0070661 172 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
regulation of feeding behavior GO:0060259 3 0.019
regulation of systemic arterial blood pressure GO:0003073 61 0.019
regulation of membrane potential GO:0042391 192 0.019
protein maturation GO:0051604 176 0.019
regulation of hydrolase activity GO:0051336 246 0.019
regulation of cell cycle process GO:0010564 160 0.019
organelle fission GO:0048285 170 0.019
regulation of lymphocyte differentiation GO:0045619 107 0.019
regulation of cell activation GO:0050865 289 0.019
maintenance of location GO:0051235 89 0.019
muscle fiber development GO:0048747 76 0.018
protein processing GO:0016485 163 0.018
regulation of cell growth GO:0001558 91 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
muscle system process GO:0003012 141 0.018
positive regulation of t cell activation GO:0050870 101 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
cell growth GO:0016049 130 0.017
engulfment of apoptotic cell GO:0043652 3 0.017
homeostasis of number of cells GO:0048872 210 0.017
regulation of defense response GO:0031347 233 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
regulation of protein kinase activity GO:0045859 232 0.017
proteoglycan metabolic process GO:0006029 38 0.017
muscle cell development GO:0055001 133 0.017
skeletal muscle fiber development GO:0048741 58 0.016
extracellular structure organization GO:0043062 148 0.016
kidney development GO:0001822 213 0.016
regulation of protein secretion GO:0050708 82 0.016
ion transmembrane transport GO:0034220 361 0.016
neural tube formation GO:0001841 108 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
lateral inhibition GO:0046331 1 0.016
steroid metabolic process GO:0008202 119 0.016
translation GO:0006412 93 0.016
camera type eye development GO:0043010 266 0.016
response to inorganic substance GO:0010035 96 0.016
embryonic epithelial tube formation GO:0001838 130 0.016
cytokine production GO:0001816 319 0.016
regulation of lymphocyte mediated immunity GO:0002706 84 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
mucopolysaccharide metabolic process GO:1903510 25 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
regulation of striated muscle cell differentiation GO:0051153 81 0.015
aminoglycan metabolic process GO:0006022 34 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
membrane organization GO:0061024 245 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.015
regulation of myoblast differentiation GO:0045661 29 0.015
cellular alcohol biosynthetic process GO:0044108 3 0.015
rho protein signal transduction GO:0007266 32 0.015
carbohydrate metabolic process GO:0005975 230 0.015
t cell mediated immunity GO:0002456 50 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
molting cycle GO:0042303 90 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
compound eye development GO:0048749 1 0.015
regulation of cell projection organization GO:0031344 206 0.015
urogenital system development GO:0001655 261 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
lymphocyte differentiation GO:0030098 242 0.015
glycosylation GO:0070085 62 0.015
oxidation reduction process GO:0055114 342 0.014
hair cycle GO:0042633 90 0.014
cytokine mediated signaling pathway GO:0019221 115 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
protein localization to membrane GO:0072657 108 0.014
regulation of mapk cascade GO:0043408 248 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
regulation of secretion by cell GO:1903530 249 0.014
regulation of transmembrane transport GO:0034762 128 0.014
extracellular matrix organization GO:0030198 147 0.014
organic acid transport GO:0015849 101 0.014
leukocyte homeostasis GO:0001776 79 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
lipid biosynthetic process GO:0008610 179 0.013
secondary alcohol metabolic process GO:1902652 3 0.013
response to lipopolysaccharide GO:0032496 128 0.013
regulation of t cell mediated immunity GO:0002709 34 0.013
positive regulation of cell development GO:0010720 237 0.013
calcitriol biosynthetic process from calciol GO:0036378 3 0.013
organ growth GO:0035265 117 0.013
regulation of organelle organization GO:0033043 289 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
sequestering of metal ion GO:0051238 19 0.013
regulation of secretion GO:0051046 274 0.013
response to acid chemical GO:0001101 111 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
mitotic cell cycle GO:0000278 195 0.012
regulation of ion transport GO:0043269 215 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
negative regulation of muscle cell differentiation GO:0051148 33 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
response to organonitrogen compound GO:0010243 246 0.012
regulation of t cell differentiation GO:0045580 83 0.012
sensory perception GO:0007600 245 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
embryonic placenta development GO:0001892 98 0.012
regulation of homeostatic process GO:0032844 182 0.012
negative regulation of leukocyte proliferation GO:0070664 46 0.012
cellular protein catabolic process GO:0044257 155 0.012
defense response to virus GO:0051607 68 0.012
intracellular protein transport GO:0006886 204 0.012
regulation of binding GO:0051098 111 0.012
protein ubiquitination GO:0016567 171 0.012
myotube cell development GO:0014904 60 0.012
regulation of proteolysis GO:0030162 164 0.012
proton transport GO:0015992 35 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
epithelial tube formation GO:0072175 130 0.012
negative regulation of cell activation GO:0050866 111 0.012
negative regulation of protein modification process GO:0031400 163 0.012
spermatid development GO:0007286 108 0.012
organophosphate catabolic process GO:0046434 232 0.012
vitamin d biosynthetic process GO:0042368 3 0.012
positive regulation of immune effector process GO:0002699 107 0.012
regulation of translation GO:0006417 71 0.012
positive regulation of cytokine production GO:0001819 174 0.012
regulation of myotube differentiation GO:0010830 62 0.012
metal ion homeostasis GO:0055065 189 0.012
regulation of cytoplasmic transport GO:1903649 112 0.011
organic acid biosynthetic process GO:0016053 86 0.011
meiotic nuclear division GO:0007126 115 0.011
cellularization GO:0007349 1 0.011
nucleotide metabolic process GO:0009117 332 0.011
cytoplasmic transport GO:0016482 234 0.011
meiosis i GO:0007127 60 0.011
regulation of leukocyte apoptotic process GO:2000106 56 0.011
binding of sperm to zona pellucida GO:0007339 34 0.011
regulation of adaptive immune response GO:0002819 90 0.011
cellular response to metal ion GO:0071248 31 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
myoblast differentiation GO:0045445 52 0.011
sperm egg recognition GO:0035036 37 0.011
glycerolipid metabolic process GO:0046486 122 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
placenta development GO:0001890 140 0.011
protein glycosylation GO:0006486 55 0.011
calcium ion transport GO:0006816 159 0.011
vitamin d3 metabolic process GO:0070640 3 0.011
nucleotide catabolic process GO:0009166 217 0.011
epithelial cell proliferation GO:0050673 174 0.011
negative regulation of protein maturation GO:1903318 79 0.011
regulation of cellular response to stress GO:0080135 159 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
action potential GO:0001508 78 0.011
skeletal muscle organ development GO:0060538 163 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
negative regulation of t cell activation GO:0050868 65 0.011
t cell differentiation GO:0030217 174 0.011
regulation of protein stability GO:0031647 52 0.011
positive regulation of kinase activity GO:0033674 155 0.011
cell cell recognition GO:0009988 44 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
cardiac chamber development GO:0003205 108 0.010
response to insulin GO:0032868 100 0.010
female gamete generation GO:0007292 74 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.010
sodium ion transport GO:0006814 73 0.010
sensory perception of sound GO:0007605 97 0.010
small molecule biosynthetic process GO:0044283 132 0.010
negative regulation of hydrolase activity GO:0051346 71 0.010
regulation of intracellular transport GO:0032386 159 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
defecation GO:0030421 1 0.010
regulation of angiotensin levels in blood GO:0002002 4 0.010
ear development GO:0043583 200 0.010
inflammatory response GO:0006954 244 0.010
negative regulation of proteolysis GO:0045861 74 0.010
negative regulation of t cell proliferation GO:0042130 38 0.010
chemotaxis GO:0006935 247 0.010

Defb4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.014
disease by infectious agent DOID:0050117 0 0.012
viral infectious disease DOID:934 0 0.012
dengue disease DOID:12205 0 0.012