Mus musculus

66 known processes

Med25

mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)

(Aliases: ESTM2,X83308,2610529E18Rik,2610034E13Rik)

Med25 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein catabolic process GO:0030163 221 0.041
macromolecule catabolic process GO:0009057 281 0.040
intracellular receptor signaling pathway GO:0030522 74 0.040
immune effector process GO:0002252 321 0.039
Fly
positive regulation of cell death GO:0010942 224 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
striated muscle tissue development GO:0014706 293 0.036
ras protein signal transduction GO:0007265 77 0.034
nitrogen compound transport GO:0071705 271 0.034
regulation of organelle organization GO:0033043 289 0.033
posttranscriptional regulation of gene expression GO:0010608 155 0.033
negative regulation of immune system process GO:0002683 209 0.033
neuronal action potential GO:0019228 54 0.033
covalent chromatin modification GO:0016569 163 0.031
lipid biosynthetic process GO:0008610 179 0.031
compound eye development GO:0048749 1 0.030
response to molecule of bacterial origin GO:0002237 143 0.030
limb morphogenesis GO:0035108 149 0.030
regulation of translational initiation GO:0006446 15 0.029
positive regulation of organelle organization GO:0010638 128 0.029
ribose phosphate metabolic process GO:0019693 291 0.028
male gamete generation GO:0048232 285 0.028
aromatic compound catabolic process GO:0019439 286 0.028
appendage development GO:0048736 166 0.028
endocytosis GO:0006897 168 0.028
cellular ketone metabolic process GO:0042180 84 0.028
homeostasis of number of cells GO:0048872 210 0.027
muscle tissue development GO:0060537 308 0.027
wnt signaling pathway GO:0016055 188 0.027
response to peptide hormone GO:0043434 127 0.026
positive regulation of cholesterol homeostasis GO:2000189 2 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
cellular protein catabolic process GO:0044257 155 0.026
negative regulation of cell proliferation GO:0008285 296 0.026
Human
modulation by virus of host morphology or physiology GO:0019048 3 0.026
regulation of cell cycle GO:0051726 281 0.025
Human
regulation of cellular ketone metabolic process GO:0010565 66 0.025
kidney development GO:0001822 213 0.025
antimicrobial peptide biosynthetic process GO:0002777 2 0.025
Fly
protein processing GO:0016485 163 0.025
ubiquitin dependent protein catabolic process GO:0006511 129 0.025
response to acid chemical GO:0001101 111 0.024
digestive system development GO:0055123 200 0.024
organic acid biosynthetic process GO:0016053 86 0.024
regulation of antimicrobial humoral response GO:0002759 3 0.024
Fly
protein modification by small protein conjugation GO:0032446 187 0.023
translation GO:0006412 93 0.022
regulation of neuron differentiation GO:0045664 281 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
multicellular organismal signaling GO:0035637 91 0.022
glucose homeostasis GO:0042593 128 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
regulation of binding GO:0051098 111 0.022
Human
regulation of translation GO:0006417 71 0.022
amine metabolic process GO:0009308 45 0.022
sterol homeostasis GO:0055092 45 0.022
cytokine production GO:0001816 319 0.022
modification dependent protein catabolic process GO:0019941 133 0.022
stem cell differentiation GO:0048863 268 0.022
cellular homeostasis GO:0019725 240 0.022
chromatin organization GO:0006325 206 0.021
cellular response to hormone stimulus GO:0032870 150 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
peptidyl amino acid modification GO:0018193 336 0.021
sensory perception GO:0007600 245 0.021
cellular response to dna damage stimulus GO:0006974 207 0.021
cell type specific apoptotic process GO:0097285 268 0.021
development of primary sexual characteristics GO:0045137 143 0.020
nucleocytoplasmic transport GO:0006913 139 0.020
response to organonitrogen compound GO:0010243 246 0.020
membrane organization GO:0061024 245 0.020
carboxylic acid biosynthetic process GO:0046394 86 0.020
spermatogenesis GO:0007283 284 0.020
regulation of system process GO:0044057 200 0.020
regionalization GO:0003002 337 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
circulatory system process GO:0003013 197 0.020
negative regulation of translational initiation GO:0045947 4 0.019
transmission of nerve impulse GO:0019226 76 0.019
muscle cell differentiation GO:0042692 261 0.019
microtubule based process GO:0007017 236 0.019
antimicrobial peptide production GO:0002775 2 0.019
Fly
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
cytoplasmic transport GO:0016482 234 0.019
oxidation reduction process GO:0055114 342 0.019
cholesterol homeostasis GO:0042632 44 0.019
oocyte axis specification GO:0007309 2 0.019
protein localization to organelle GO:0033365 185 0.019
limb development GO:0060173 166 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
mitotic cell cycle GO:0000278 195 0.018
peptide secretion GO:0002790 114 0.018
skeletal muscle organ development GO:0060538 163 0.018
myeloid cell homeostasis GO:0002262 114 0.018
regulation of homeostatic process GO:0032844 182 0.018
positive regulation of translational initiation GO:0045948 4 0.018
cellular response to peptide GO:1901653 92 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
multi multicellular organism process GO:0044706 109 0.018
carbohydrate homeostasis GO:0033500 128 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.018
regulation of mitotic cell cycle GO:0007346 126 0.017
positive regulation of steroid biosynthetic process GO:0010893 4 0.017
cellular response to lipid GO:0071396 145 0.017
midgut development GO:0007494 4 0.017
peptide transport GO:0015833 133 0.017
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
translational initiation GO:0006413 24 0.017
regulation of cell cycle process GO:0010564 160 0.017
Human
organ growth GO:0035265 117 0.017
carbohydrate metabolic process GO:0005975 230 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
regulation of cytokine production GO:0001817 266 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
heterocycle catabolic process GO:0046700 280 0.017
cellular response to peptide hormone stimulus GO:0071375 92 0.017
urogenital system development GO:0001655 261 0.017
amide transport GO:0042886 138 0.017
intracellular protein transport GO:0006886 204 0.017
microtubule cytoskeleton organization GO:0000226 157 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
embryonic placenta development GO:0001892 98 0.016
meiotic nuclear division GO:0007126 115 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
protein localization to nucleus GO:0034504 121 0.016
telencephalon development GO:0021537 186 0.016
protein targeting GO:0006605 143 0.016
cellular response to lipopolysaccharide GO:0071222 77 0.016
proteasomal protein catabolic process GO:0010498 98 0.016
oocyte construction GO:0007308 2 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
fat cell differentiation GO:0045444 160 0.016
nucleobase containing small molecule metabolic process GO:0055086 352 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
regulation of cell activation GO:0050865 289 0.016
lipid homeostasis GO:0055088 63 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
regulation of anatomical structure size GO:0090066 178 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
positive regulation of apoptotic process GO:0043065 217 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
cellular amide metabolic process GO:0043603 58 0.015
Fly
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.015
regulation of membrane potential GO:0042391 192 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
actin cytoskeleton organization GO:0030036 220 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
regulation of hormone levels GO:0010817 211 0.015
neural tube development GO:0021915 160 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
fatty acid metabolic process GO:0006631 121 0.015
connective tissue development GO:0061448 179 0.015
ossification GO:0001503 216 0.015
cellular lipid metabolic process GO:0044255 323 0.015
gland development GO:0048732 330 0.014
multicellular organism growth GO:0035264 161 0.014
respiratory tube development GO:0030323 167 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
harderian gland development GO:0070384 2 0.014
rhythmic process GO:0048511 174 0.014
stem cell maintenance GO:0019827 130 0.014
cell adhesion GO:0007155 329 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
liver development GO:0001889 66 0.014
inflammatory response GO:0006954 244 0.014
regulation of hormone secretion GO:0046883 88 0.014
lipid transport GO:0006869 98 0.014
forebrain development GO:0030900 302 0.014
epithelial cell development GO:0002064 159 0.014
regulation of peptide transport GO:0090087 91 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
regulation of cell cycle phase transition GO:1901987 77 0.014
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.014
regulation of secretion GO:0051046 274 0.014
circadian rhythm GO:0007623 114 0.014
wound healing GO:0042060 157 0.014
myotube differentiation GO:0014902 105 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.014
cellular response to organic cyclic compound GO:0071407 87 0.014
regulation of hydrolase activity GO:0051336 246 0.014
cellular chemical homeostasis GO:0055082 215 0.014
maintenance of location GO:0051235 89 0.014
purine containing compound metabolic process GO:0072521 311 0.013
response to peptide GO:1901652 136 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
embryonic appendage morphogenesis GO:0035113 126 0.013
regulation of circadian rhythm GO:0042752 58 0.013
protein ubiquitination GO:0016567 171 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
lung development GO:0030324 164 0.013
negative regulation of cytokine production GO:0001818 84 0.013
response to inorganic substance GO:0010035 96 0.013
camera type eye development GO:0043010 266 0.013
gliogenesis GO:0042063 141 0.013
negative regulation of nervous system development GO:0051961 156 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
rho protein signal transduction GO:0007266 32 0.013
nuclear import GO:0051170 95 0.013
regulation of feeding behavior GO:0060259 3 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
purine containing compound catabolic process GO:0072523 213 0.013
negative regulation of granulocyte differentiation GO:0030853 3 0.013
lateral inhibition GO:0046331 1 0.013
cardiac muscle tissue development GO:0048738 130 0.013
positive regulation of cell development GO:0010720 237 0.013
placenta development GO:0001890 140 0.013
response to temperature stimulus GO:0009266 55 0.013
negative regulation of protein modification process GO:0031400 163 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
action potential GO:0001508 78 0.012
positive regulation of protein modification process GO:0031401 299 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
regulation of cell motility GO:2000145 236 0.012
regulation of protein kinase activity GO:0045859 232 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
pallium development GO:0021543 120 0.012
cardiac chamber morphogenesis GO:0003206 93 0.012
regulation of protein catabolic process GO:0042176 108 0.012
regulation of antimicrobial peptide production GO:0002784 1 0.012
Fly
organophosphate catabolic process GO:0046434 232 0.012
protein import GO:0017038 101 0.012
notch signaling pathway GO:0007219 71 0.012
embryonic limb morphogenesis GO:0030326 126 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
regulation of tumor necrosis factor production GO:0032680 49 0.012
cardiocyte differentiation GO:0035051 87 0.012
cellular response to acid chemical GO:0071229 68 0.012
cilium morphogenesis GO:0060271 102 0.012
learning or memory GO:0007611 148 0.012
respiratory system development GO:0060541 190 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
regulation of protein processing GO:0070613 96 0.012
asymmetric neuroblast division GO:0055059 1 0.012
macromolecule methylation GO:0043414 120 0.012
germ cell development GO:0007281 185 0.012
modification by symbiont of host morphology or physiology GO:0044003 4 0.012
regulation of cellular amino acid metabolic process GO:0006521 5 0.012
nucleoside metabolic process GO:0009116 246 0.012
gene silencing by rna GO:0031047 19 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.011
histone modification GO:0016570 159 0.011
epithelial tube formation GO:0072175 130 0.011
digestive tract morphogenesis GO:0048546 147 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
localization within membrane GO:0051668 4 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
positive regulation of nervous system development GO:0051962 221 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
regulation of cell projection organization GO:0031344 206 0.011
regulation of neuron projection development GO:0010975 169 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
digestive tract development GO:0048565 190 0.011
regulation of cellular component size GO:0032535 121 0.011
positive regulation of immune effector process GO:0002699 107 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
negative regulation of female receptivity GO:0007621 2 0.011
regulation of cholesterol homeostasis GO:2000188 9 0.011
response to lipopolysaccharide GO:0032496 128 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
regulation of peptide hormone secretion GO:0090276 75 0.011
hindbrain development GO:0030902 128 0.011
lipid localization GO:0010876 126 0.011
response to monosaccharide GO:0034284 67 0.011
regulation of inflammatory response GO:0050727 147 0.011
regulation of protein complex disassembly GO:0043244 28 0.011
nuclear transport GO:0051169 139 0.011
insulin secretion GO:0030073 89 0.011
muscle system process GO:0003012 141 0.011
regulation of secretion by cell GO:1903530 249 0.011
tube formation GO:0035148 140 0.011
skeletal system development GO:0001501 356 0.010
circadian regulation of gene expression GO:0032922 48 0.010
purine nucleotide metabolic process GO:0006163 302 0.010
leukocyte activation involved in immune response GO:0002366 126 0.010
bone development GO:0060348 120 0.010
mitotic cell cycle process GO:1903047 159 0.010
regulation of cell migration GO:0030334 219 0.010
sensory perception of mechanical stimulus GO:0050954 107 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.010
epithelial cell proliferation GO:0050673 174 0.010
small molecule biosynthetic process GO:0044283 132 0.010
cell substrate adhesion GO:0031589 130 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
steroid metabolic process GO:0008202 119 0.010
cartilage development GO:0051216 140 0.010
axonogenesis GO:0007409 274 0.010
endomembrane system organization GO:0010256 147 0.010
monocarboxylic acid biosynthetic process GO:0072330 61 0.010
cellular component assembly involved in morphogenesis GO:0010927 139 0.010
nuclear division GO:0000280 158 0.010
organic hydroxy compound biosynthetic process GO:1901617 77 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
positive regulation of neuron differentiation GO:0045666 141 0.010
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.010
multicellular organismal homeostasis GO:0048871 164 0.010

Med25 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
Human
nervous system disease DOID:863 0 0.024
Human
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.013
neuromuscular disease DOID:440 0 0.011
Human
neuropathy DOID:870 0 0.011
Human