Mus musculus

0 known processes

Ak4

adenylate kinase 4

(Aliases: Ak-3,Ak3,Ak3l1,D4Ertd274e,Ak-4)

Ak4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.358
monocarboxylic acid metabolic process GO:0032787 191 0.133
transmembrane transport GO:0055085 412 0.121
anion transport GO:0006820 177 0.115
cellular ketone metabolic process GO:0042180 84 0.109
alpha amino acid metabolic process GO:1901605 59 0.092
cellular amine metabolic process GO:0044106 44 0.092
cellular lipid metabolic process GO:0044255 323 0.091
cation transport GO:0006812 399 0.087
organic acid transport GO:0015849 101 0.076
regulation of protein kinase activity GO:0045859 232 0.076
peptidyl amino acid modification GO:0018193 336 0.076
oxidation reduction process GO:0055114 342 0.075
regulation of cellular amino acid metabolic process GO:0006521 5 0.074
organic anion transport GO:0015711 137 0.074
regulation of cellular amine metabolic process GO:0033238 20 0.070
carboxylic acid transport GO:0046942 100 0.065
regulation of cellular ketone metabolic process GO:0010565 66 0.065
carbohydrate metabolic process GO:0005975 230 0.064
cation homeostasis GO:0055080 212 0.063
nitrogen compound transport GO:0071705 271 0.062
membrane organization GO:0061024 245 0.061
synaptic transmission GO:0007268 329 0.059
amine metabolic process GO:0009308 45 0.057
lipid biosynthetic process GO:0008610 179 0.053
cellular homeostasis GO:0019725 240 0.052
regulation of membrane potential GO:0042391 192 0.050
mitochondrion organization GO:0007005 134 0.049
cellular chemical homeostasis GO:0055082 215 0.049
nucleotide metabolic process GO:0009117 332 0.047
Human Yeast
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.047
nucleobase containing small molecule metabolic process GO:0055086 352 0.044
Human Yeast
purine nucleoside triphosphate metabolic process GO:0009144 226 0.043
Human
purine ribonucleoside metabolic process GO:0046128 241 0.043
Human
regulation of kinase activity GO:0043549 249 0.042
cation transmembrane transport GO:0098655 266 0.042
cellular modified amino acid metabolic process GO:0006575 63 0.041
apoptotic signaling pathway GO:0097190 306 0.041
glycerolipid metabolic process GO:0046486 122 0.039
negative regulation of molecular function GO:0044092 258 0.039
ion transmembrane transport GO:0034220 361 0.039
cellular carbohydrate metabolic process GO:0044262 119 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.037
organic hydroxy compound metabolic process GO:1901615 203 0.037
glucose homeostasis GO:0042593 128 0.037
nucleoside metabolic process GO:0009116 246 0.036
Human
regulation of ion transport GO:0043269 215 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.036
Human Yeast
nucleotide catabolic process GO:0009166 217 0.035
regulation of mapk cascade GO:0043408 248 0.035
sulfur compound metabolic process GO:0006790 100 0.035
organonitrogen compound biosynthetic process GO:1901566 192 0.035
regulation of transferase activity GO:0051338 263 0.034
kidney development GO:0001822 213 0.033
purine containing compound metabolic process GO:0072521 311 0.033
Human
negative regulation of protein metabolic process GO:0051248 282 0.033
organophosphate catabolic process GO:0046434 232 0.032
epidermis development GO:0008544 187 0.032
ribonucleotide metabolic process GO:0009259 291 0.031
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
mapk cascade GO:0000165 281 0.031
regulation of organelle organization GO:0033043 289 0.031
lipid transport GO:0006869 98 0.031
carbohydrate homeostasis GO:0033500 128 0.031
heterocycle catabolic process GO:0046700 280 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
Human
glycosyl compound metabolic process GO:1901657 246 0.030
Human
macromolecule catabolic process GO:0009057 281 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
Human
renal system development GO:0072001 225 0.030
ribonucleoside metabolic process GO:0009119 245 0.030
Human
cofactor metabolic process GO:0051186 80 0.030
monocarboxylic acid transport GO:0015718 44 0.029
regulation of hormone levels GO:0010817 211 0.029
cellular response to hormone stimulus GO:0032870 150 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
amide transport GO:0042886 138 0.029
organonitrogen compound catabolic process GO:1901565 264 0.029
lipid localization GO:0010876 126 0.028
peptide transport GO:0015833 133 0.028
gland development GO:0048732 330 0.028
anion transmembrane transport GO:0098656 71 0.028
purine ribonucleoside catabolic process GO:0046130 205 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
amino acid transmembrane transport GO:0003333 37 0.028
ras protein signal transduction GO:0007265 77 0.027
protein maturation GO:0051604 176 0.027
response to organonitrogen compound GO:0010243 246 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
Human
cell adhesion GO:0007155 329 0.026
aromatic compound catabolic process GO:0019439 286 0.026
coenzyme metabolic process GO:0006732 52 0.025
phospholipid metabolic process GO:0006644 87 0.025
skin development GO:0043588 220 0.025
small gtpase mediated signal transduction GO:0007264 97 0.025
organic acid biosynthetic process GO:0016053 86 0.024
endomembrane system organization GO:0010256 147 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
cellular ion homeostasis GO:0006873 165 0.024
negative regulation of phosphate metabolic process GO:0045936 184 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.023
cellular response to organonitrogen compound GO:0071417 145 0.023
urogenital system development GO:0001655 261 0.023
regulation of secretion GO:0051046 274 0.023
carboxylic acid biosynthetic process GO:0046394 86 0.023
fatty acid metabolic process GO:0006631 121 0.023
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
negative regulation of protein modification process GO:0031400 163 0.023
cellular protein complex assembly GO:0043623 116 0.022
respiratory system development GO:0060541 190 0.022
response to organic cyclic compound GO:0014070 198 0.022
learning or memory GO:0007611 148 0.022
locomotory behavior GO:0007626 195 0.022
amino acid transport GO:0006865 61 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
regulation of hydrolase activity GO:0051336 246 0.022
response to oxygen levels GO:0070482 62 0.022
regulation of cellular response to stress GO:0080135 159 0.021
response to extracellular stimulus GO:0009991 127 0.021
glycerophospholipid metabolic process GO:0006650 71 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
intracellular protein transport GO:0006886 204 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
blood vessel morphogenesis GO:0048514 285 0.021
small molecule catabolic process GO:0044282 71 0.021
regulation of cell cycle GO:0051726 281 0.021
organelle localization GO:0051640 179 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
Human
sodium ion transport GO:0006814 73 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
Human
cognition GO:0050890 149 0.020
synapse organization GO:0050808 125 0.020
positive regulation of mapk cascade GO:0043410 170 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
response to nutrient levels GO:0031667 109 0.020
action potential GO:0001508 78 0.019
sensory perception GO:0007600 245 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
nucleoside catabolic process GO:0009164 206 0.019
positive regulation of kinase activity GO:0033674 155 0.019
positive regulation of protein kinase activity GO:0045860 144 0.019
cellular amino acid catabolic process GO:0009063 25 0.019
protein processing GO:0016485 163 0.019
cellular response to peptide GO:1901653 92 0.019
response to peptide GO:1901652 136 0.019
purine nucleoside catabolic process GO:0006152 205 0.018
stem cell differentiation GO:0048863 268 0.018
oocyte construction GO:0007308 2 0.018
epithelial cell proliferation GO:0050673 174 0.018
positive regulation of organelle organization GO:0010638 128 0.018
fat cell differentiation GO:0045444 160 0.018
regulation of transmembrane transport GO:0034762 128 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
cell type specific apoptotic process GO:0097285 268 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
neuron neuron synaptic transmission GO:0007270 69 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.018
response to oxidative stress GO:0006979 123 0.018
regulation of neuron differentiation GO:0045664 281 0.018
aspartate family amino acid metabolic process GO:0009066 10 0.018
generation of precursor metabolites and energy GO:0006091 103 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
Human
actin cytoskeleton organization GO:0030036 220 0.018
response to peptide hormone GO:0043434 127 0.017
small molecule biosynthetic process GO:0044283 132 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
Human
peptide hormone secretion GO:0030072 109 0.017
rho protein signal transduction GO:0007266 32 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
negative regulation of hydrolase activity GO:0051346 71 0.017
positive regulation of protein modification process GO:0031401 299 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
fertilization GO:0009566 127 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
hexose metabolic process GO:0019318 98 0.017
regulation of lipid metabolic process GO:0019216 118 0.017
muscle tissue development GO:0060537 308 0.017
positive regulation of transferase activity GO:0051347 167 0.017
lipoprotein metabolic process GO:0042157 43 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
cellular response to insulin stimulus GO:0032869 78 0.016
plasma membrane organization GO:0007009 90 0.016
regulation of system process GO:0044057 200 0.016
germ cell development GO:0007281 185 0.016
purine containing compound catabolic process GO:0072523 213 0.016
organic hydroxy compound transport GO:0015850 93 0.016
forebrain development GO:0030900 302 0.016
response to insulin GO:0032868 100 0.016
nuclear division GO:0000280 158 0.016
protein ubiquitination GO:0016567 171 0.016
organelle fission GO:0048285 170 0.016
monosaccharide metabolic process GO:0005996 106 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
ear development GO:0043583 200 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
neurotransmitter transport GO:0006836 76 0.016
learning GO:0007612 98 0.016
nuclear transport GO:0051169 139 0.016
blood circulation GO:0008015 195 0.016
regulation of body fluid levels GO:0050878 162 0.016
endocytosis GO:0006897 168 0.016
protein oligomerization GO:0051259 67 0.016
adult behavior GO:0030534 135 0.016
regulation of neurotransmitter levels GO:0001505 87 0.016
morphogenesis of a branching structure GO:0001763 203 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.015
respiratory tube development GO:0030323 167 0.015
hormone secretion GO:0046879 128 0.015
spermatogenesis GO:0007283 284 0.015
steroid metabolic process GO:0008202 119 0.015
regulation of protein localization GO:0032880 231 0.015
regulation of chloride transport GO:2001225 2 0.015
regulation of anatomical structure size GO:0090066 178 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
establishment of vesicle localization GO:0051650 81 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
sodium ion transmembrane transport GO:0035725 49 0.015
inorganic anion transport GO:0015698 43 0.015
protein targeting GO:0006605 143 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
Human
protein catabolic process GO:0030163 221 0.015
regulation of cell adhesion GO:0030155 154 0.015
metal ion homeostasis GO:0055065 189 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
response to decreased oxygen levels GO:0036293 59 0.015
neuron apoptotic process GO:0051402 142 0.015
single organism cell adhesion GO:0098602 156 0.014
regulation of secretion by cell GO:1903530 249 0.014
sensory organ morphogenesis GO:0090596 242 0.014
regulation of proteolysis GO:0030162 164 0.014
oocyte axis specification GO:0007309 2 0.014
positive regulation of cell development GO:0010720 237 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
insulin secretion GO:0030073 89 0.014
skeletal system development GO:0001501 356 0.014
cytoplasmic transport GO:0016482 234 0.014
mitotic cell cycle process GO:1903047 159 0.014
protein localization to organelle GO:0033365 185 0.014
ossification GO:0001503 216 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
positive regulation of cell death GO:0010942 224 0.014
cell growth GO:0016049 130 0.014
regulation of cell migration GO:0030334 219 0.014
dephosphorylation GO:0016311 129 0.014
actin filament organization GO:0007015 113 0.014
protein polymerization GO:0051258 57 0.014
exocytosis GO:0006887 121 0.014
divalent inorganic cation transport GO:0072511 178 0.014
cellular response to lipid GO:0071396 145 0.014
microtubule based process GO:0007017 236 0.014
regulation of homeostatic process GO:0032844 182 0.013
regulation of anion transport GO:0044070 27 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
axonogenesis GO:0007409 274 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
neuron death GO:0070997 154 0.013
negative regulation of organelle organization GO:0010639 90 0.013
apoptotic mitochondrial changes GO:0008637 48 0.013
cell maturation GO:0048469 127 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
positive regulation of nervous system development GO:0051962 221 0.013
protein localization to membrane GO:0072657 108 0.013
response to radiation GO:0009314 165 0.013
cellular response to carbohydrate stimulus GO:0071322 50 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
Human
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
regulation of metal ion transport GO:0010959 106 0.013
carbohydrate biosynthetic process GO:0016051 74 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
developmental maturation GO:0021700 193 0.013
atp metabolic process GO:0046034 75 0.013
Human
regulation of peptidase activity GO:0052547 96 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
response to inorganic substance GO:0010035 96 0.013
l amino acid transport GO:0015807 32 0.013
response to acid chemical GO:0001101 111 0.012
glucose metabolic process GO:0006006 92 0.012
chloride transport GO:0006821 32 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
regulation of protein processing GO:0070613 96 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
circulatory system process GO:0003013 197 0.012
response to drug GO:0042493 75 0.012
positive regulation of growth GO:0045927 104 0.012
regulation of peptide transport GO:0090087 91 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
chemotaxis GO:0006935 247 0.012
regulation of synaptic plasticity GO:0048167 87 0.012
rhythmic process GO:0048511 174 0.012
maintenance of location GO:0051235 89 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
epithelial cell development GO:0002064 159 0.012
lipid modification GO:0030258 65 0.012
store operated calcium entry GO:0002115 7 0.012
multicellular organism growth GO:0035264 161 0.012
regulation of hormone secretion GO:0046883 88 0.012
regulation of carbohydrate metabolic process GO:0006109 75 0.012
multi multicellular organism process GO:0044706 109 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
circadian rhythm GO:0007623 114 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
Human
regulation of peptide secretion GO:0002791 77 0.012
striated muscle tissue development GO:0014706 293 0.012
regulation of cell projection organization GO:0031344 206 0.012
establishment of organelle localization GO:0051656 122 0.012
wnt signaling pathway GO:0016055 188 0.012
oligopeptide transmembrane transport GO:0035672 4 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of feeding behavior GO:0060259 3 0.012
lateral inhibition GO:0046331 1 0.011
dna metabolic process GO:0006259 303 0.011
negative regulation of transferase activity GO:0051348 85 0.011
bone development GO:0060348 120 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
development of primary sexual characteristics GO:0045137 143 0.011
intracellular mrna localization GO:0008298 4 0.011
regulation of neuron projection development GO:0010975 169 0.011
angiogenesis GO:0001525 201 0.011
cell substrate adhesion GO:0031589 130 0.011
mitochondrion distribution GO:0048311 4 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
peptide secretion GO:0002790 114 0.011
l alpha amino acid transmembrane transport GO:1902475 23 0.011
regulation of map kinase activity GO:0043405 120 0.011
telencephalon development GO:0021537 186 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
calcium ion homeostasis GO:0055074 127 0.011
negative regulation of protein processing GO:0010955 79 0.011
skeletal system morphogenesis GO:0048705 203 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
Human
carboxylic acid catabolic process GO:0046395 51 0.011
homeostasis of number of cells GO:0048872 210 0.011
male gamete generation GO:0048232 285 0.011
insulin receptor signaling pathway GO:0008286 49 0.011
branching morphogenesis of an epithelial tube GO:0048754 159 0.011
vesicle localization GO:0051648 86 0.011
inflammatory response GO:0006954 244 0.011
limb development GO:0060173 166 0.011
gtp catabolic process GO:0006184 143 0.011
erk1 and erk2 cascade GO:0070371 77 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
extracellular matrix organization GO:0030198 147 0.011
mitotic cell cycle GO:0000278 195 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
negative regulation of neuron apoptotic process GO:0043524 92 0.010
pallium development GO:0021543 120 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
alcohol metabolic process GO:0006066 116 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
regulation of protein maturation GO:1903317 96 0.010
rna processing GO:0006396 105 0.010
monovalent inorganic cation homeostasis GO:0055067 33 0.010
response to light stimulus GO:0009416 135 0.010
regulation of cellular component size GO:0032535 121 0.010
regulation of ph GO:0006885 26 0.010
regulation of ossification GO:0030278 112 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
rac protein signal transduction GO:0016601 13 0.010
regulation of cell motility GO:2000145 236 0.010
gonad development GO:0008406 141 0.010
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.010
organ growth GO:0035265 117 0.010
gtp metabolic process GO:0046039 144 0.010
Human
modification dependent macromolecule catabolic process GO:0043632 133 0.010
cholesterol metabolic process GO:0008203 56 0.010
muscle system process GO:0003012 141 0.010
lung development GO:0030324 164 0.010
spermatid differentiation GO:0048515 115 0.010
cell junction organization GO:0034330 77 0.010
actin filament polymerization GO:0030041 44 0.010
negative regulation of protein maturation GO:1903318 79 0.010

Ak4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.022
central nervous system disease DOID:331 0 0.020
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
inherited metabolic disorder DOID:655 0 0.017
neurodegenerative disease DOID:1289 0 0.015
immune system disease DOID:2914 0 0.015
hematopoietic system disease DOID:74 0 0.012
musculoskeletal system disease DOID:17 0 0.011