Mus musculus

26 known processes

Thop1

thimet oligopeptidase 1

(Aliases: EP24.15,AI131655,AI327041)

Thop1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular ketone metabolic process GO:0010565 66 0.086
Mouse
heterocycle catabolic process GO:0046700 280 0.067
cellular amino acid metabolic process GO:0006520 103 0.067
microtubule based process GO:0007017 236 0.060
aromatic compound catabolic process GO:0019439 286 0.057
cellular ketone metabolic process GO:0042180 84 0.057
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
nucleoside triphosphate metabolic process GO:0009141 230 0.048
nucleoside triphosphate catabolic process GO:0009143 205 0.048
amine metabolic process GO:0009308 45 0.047
small gtpase mediated signal transduction GO:0007264 97 0.047
cellular nitrogen compound catabolic process GO:0044270 280 0.046
purine containing compound metabolic process GO:0072521 311 0.044
ras protein signal transduction GO:0007265 77 0.044
cellular amine metabolic process GO:0044106 44 0.044
protein catabolic process GO:0030163 221 0.044
macromolecule catabolic process GO:0009057 281 0.044
positive regulation of cellular amine metabolic process GO:0033240 5 0.043
regulation of cellular amine metabolic process GO:0033238 20 0.043
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
ribose phosphate metabolic process GO:0019693 291 0.042
transmembrane transport GO:0055085 412 0.041
purine nucleoside triphosphate metabolic process GO:0009144 226 0.041
peptidyl amino acid modification GO:0018193 336 0.041
nucleotide metabolic process GO:0009117 332 0.040
nucleoside metabolic process GO:0009116 246 0.038
ribonucleotide catabolic process GO:0009261 208 0.038
purine nucleotide metabolic process GO:0006163 302 0.038
ribonucleotide metabolic process GO:0009259 291 0.037
negative regulation of protein metabolic process GO:0051248 282 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
regulation of cellular catabolic process GO:0031329 242 0.035
purine containing compound catabolic process GO:0072523 213 0.033
purine nucleoside metabolic process GO:0042278 241 0.033
organonitrogen compound catabolic process GO:1901565 264 0.032
regulation of organelle organization GO:0033043 289 0.032
apoptotic signaling pathway GO:0097190 306 0.032
glycosyl compound catabolic process GO:1901658 206 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.031
nucleoside phosphate metabolic process GO:0006753 338 0.031
ribonucleoside catabolic process GO:0042454 206 0.031
carbohydrate derivative biosynthetic process GO:1901137 183 0.030
organonitrogen compound biosynthetic process GO:1901566 192 0.030
regulation of hydrolase activity GO:0051336 246 0.030
regulation of protein localization GO:0032880 231 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
ribonucleoside triphosphate catabolic process GO:0009203 199 0.029
single organism nuclear import GO:1902593 95 0.029
purine nucleoside triphosphate catabolic process GO:0009146 203 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.028
positive regulation of gtp catabolic process GO:0033126 85 0.028
spermatogenesis GO:0007283 284 0.028
glycosyl compound metabolic process GO:1901657 246 0.027
germ cell development GO:0007281 185 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
ion transmembrane transport GO:0034220 361 0.027
nucleoside catabolic process GO:0009164 206 0.027
ribonucleoside metabolic process GO:0009119 245 0.027
purine ribonucleotide catabolic process GO:0009154 208 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.026
nuclear division GO:0000280 158 0.026
guanosine containing compound catabolic process GO:1901069 144 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.026
intracellular protein transport GO:0006886 204 0.026
modification dependent macromolecule catabolic process GO:0043632 133 0.025
positive regulation of cellular catabolic process GO:0031331 148 0.025
regulation of nucleotide metabolic process GO:0006140 169 0.025
nucleotide catabolic process GO:0009166 217 0.025
microtubule cytoskeleton organization GO:0000226 157 0.025
regulation of transferase activity GO:0051338 263 0.025
negative regulation of molecular function GO:0044092 258 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
muscle tissue development GO:0060537 308 0.024
Mouse
regulation of purine nucleotide catabolic process GO:0033121 122 0.024
carbohydrate metabolic process GO:0005975 230 0.024
Mouse
protein localization to organelle GO:0033365 185 0.023
protein import GO:0017038 101 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
cation transport GO:0006812 399 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
organelle assembly GO:0070925 177 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.023
male gamete generation GO:0048232 285 0.023
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
organelle fission GO:0048285 170 0.022
organophosphate catabolic process GO:0046434 232 0.022
positive regulation of nucleotide catabolic process GO:0030813 88 0.022
leukocyte differentiation GO:0002521 342 0.022
cellular lipid metabolic process GO:0044255 323 0.021
mitotic cell cycle GO:0000278 195 0.021
regulation of protein kinase activity GO:0045859 232 0.021
maintenance of location GO:0051235 89 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
regulation of anatomical structure size GO:0090066 178 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
nitrogen compound transport GO:0071705 271 0.021
endocytosis GO:0006897 168 0.021
negative regulation of protein modification process GO:0031400 163 0.021
regulation of cell motility GO:2000145 236 0.020
response to organonitrogen compound GO:0010243 246 0.020
chromatin organization GO:0006325 206 0.020
regulation of ion transport GO:0043269 215 0.020
nucleocytoplasmic transport GO:0006913 139 0.020
protein glycosylation GO:0006486 55 0.020
positive regulation of protein modification process GO:0031401 299 0.020
glycoprotein metabolic process GO:0009100 116 0.020
lymphocyte differentiation GO:0030098 242 0.020
dna metabolic process GO:0006259 303 0.019
positive regulation of gtpase activity GO:0043547 85 0.019
guanosine containing compound metabolic process GO:1901068 144 0.019
regulation of protein catabolic process GO:0042176 108 0.019
regulation of cell cycle GO:0051726 281 0.019
establishment of protein localization to organelle GO:0072594 118 0.019
regulation of nucleoside metabolic process GO:0009118 130 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
cytoplasmic transport GO:0016482 234 0.019
gtp catabolic process GO:0006184 143 0.019
negative regulation of cell proliferation GO:0008285 296 0.018
sensory perception GO:0007600 245 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
cellular carbohydrate metabolic process GO:0044262 119 0.018
Mouse
camera type eye development GO:0043010 266 0.018
nuclear transport GO:0051169 139 0.018
rho protein signal transduction GO:0007266 32 0.018
protein localization to nucleus GO:0034504 121 0.018
regulation of nucleotide catabolic process GO:0030811 122 0.018
striated muscle tissue development GO:0014706 293 0.018
Mouse
mapk cascade GO:0000165 281 0.017
protein targeting GO:0006605 143 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
peptidyl serine modification GO:0018209 83 0.017
cell growth GO:0016049 130 0.017
regulation of kinase activity GO:0043549 249 0.017
regionalization GO:0003002 337 0.017
response to peptide GO:1901652 136 0.017
positive regulation of nucleoside metabolic process GO:0045979 91 0.017
lymphocyte proliferation GO:0046651 164 0.017
skeletal muscle organ development GO:0060538 163 0.017
Mouse
negative regulation of phosphorylation GO:0042326 166 0.017
protein ubiquitination GO:0016567 171 0.017
gland development GO:0048732 330 0.017
development of primary sexual characteristics GO:0045137 143 0.017
skeletal system development GO:0001501 356 0.017
spermatid differentiation GO:0048515 115 0.016
regulation of cytokine production GO:0001817 266 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
leukocyte proliferation GO:0070661 172 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
immune effector process GO:0002252 321 0.016
cytokine production GO:0001816 319 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
regulation of cell growth GO:0001558 91 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
regulation of lymphocyte activation GO:0051249 240 0.015
axonogenesis GO:0007409 274 0.015
t cell activation GO:0042110 289 0.015
histone modification GO:0016570 159 0.015
protein maturation GO:0051604 176 0.015
sensory organ morphogenesis GO:0090596 242 0.015
homeostasis of number of cells GO:0048872 210 0.015
compound eye development GO:0048749 1 0.015
mitotic cell cycle process GO:1903047 159 0.015
meiotic cell cycle GO:0051321 122 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
dendrite development GO:0016358 115 0.015
positive regulation of cell development GO:0010720 237 0.015
regulation of neuron differentiation GO:0045664 281 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
developmental maturation GO:0021700 193 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
organelle localization GO:0051640 179 0.015
regulation of cell activation GO:0050865 289 0.015
circulatory system process GO:0003013 197 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
oxidation reduction process GO:0055114 342 0.015
cell adhesion GO:0007155 329 0.015
lipid biosynthetic process GO:0008610 179 0.014
response to organic cyclic compound GO:0014070 198 0.014
rhythmic process GO:0048511 174 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
regulation of proteolysis GO:0030162 164 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
placenta development GO:0001890 140 0.014
protein processing GO:0016485 163 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
protein import into nucleus GO:0006606 95 0.014
cellular response to lipid GO:0071396 145 0.014
transmission of nerve impulse GO:0019226 76 0.014
rna processing GO:0006396 105 0.013
regulation of secretion by cell GO:1903530 249 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
skin development GO:0043588 220 0.013
regulation of protein transport GO:0051223 163 0.013
establishment of organelle localization GO:0051656 122 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
multicellular organism growth GO:0035264 161 0.013
positive regulation of transferase activity GO:0051347 167 0.013
spermatid development GO:0007286 108 0.013
response to inorganic substance GO:0010035 96 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
cell substrate adhesion GO:0031589 130 0.012
positive regulation of growth GO:0045927 104 0.012
wound healing GO:0042060 157 0.012
regulation of transmembrane transport GO:0034762 128 0.012
stem cell differentiation GO:0048863 268 0.012
meiotic nuclear division GO:0007126 115 0.012
cellular homeostasis GO:0019725 240 0.012
methylation GO:0032259 134 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
regulation of mapk cascade GO:0043408 248 0.012
actin cytoskeleton organization GO:0030036 220 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
muscle cell differentiation GO:0042692 261 0.012
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.012
protein localization to membrane GO:0072657 108 0.012
positive regulation of organelle organization GO:0010638 128 0.012
regulation of t cell activation GO:0050863 170 0.012
myeloid cell differentiation GO:0030099 233 0.012
blood vessel morphogenesis GO:0048514 285 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
action potential GO:0001508 78 0.012
regulation of gtp catabolic process GO:0033124 113 0.012
divalent metal ion transport GO:0070838 172 0.012
cell division GO:0051301 120 0.012
mitotic nuclear division GO:0007067 48 0.012
regulation of cell size GO:0008361 72 0.012
glycerolipid metabolic process GO:0046486 122 0.012
extracellular matrix organization GO:0030198 147 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.011
connective tissue development GO:0061448 179 0.011
synaptic transmission GO:0007268 329 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
embryonic placenta development GO:0001892 98 0.011
regulation of membrane potential GO:0042391 192 0.011
glucose metabolic process GO:0006006 92 0.011
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.011
telencephalon development GO:0021537 186 0.011
neuron projection guidance GO:0097485 141 0.011
peptidyl lysine modification GO:0018205 77 0.011
cellular protein complex assembly GO:0043623 116 0.011
cell type specific apoptotic process GO:0097285 268 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
negative regulation of cell cycle GO:0045786 123 0.011
ossification GO:0001503 216 0.011
stem cell development GO:0048864 219 0.011
hindbrain development GO:0030902 128 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
regulation of cell adhesion GO:0030155 154 0.011
cell activation involved in immune response GO:0002263 126 0.011
response to light stimulus GO:0009416 135 0.011
acetylcholine transport GO:0015870 2 0.011
epithelial cell proliferation GO:0050673 174 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
cellular amide metabolic process GO:0043603 58 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
regulation of cellular component size GO:0032535 121 0.011
meiosis i GO:0007127 60 0.011
retina development in camera type eye GO:0060041 119 0.011
hexose metabolic process GO:0019318 98 0.011
Mouse
modification dependent protein catabolic process GO:0019941 133 0.011
glucose homeostasis GO:0042593 128 0.011
regulation of metal ion transport GO:0010959 106 0.011
positive regulation of ras gtpase activity GO:0032320 65 0.011
endomembrane system organization GO:0010256 147 0.011
single organism cell adhesion GO:0098602 156 0.011
establishment or maintenance of cell polarity GO:0007163 86 0.011
cellular protein catabolic process GO:0044257 155 0.011
regulation of neuron projection development GO:0010975 169 0.011
cellular ion homeostasis GO:0006873 165 0.011
membrane organization GO:0061024 245 0.011
respiratory tube development GO:0030323 167 0.011
response to oxygen levels GO:0070482 62 0.011
response to acid chemical GO:0001101 111 0.011
macromolecule glycosylation GO:0043413 55 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
regulation of cell projection organization GO:0031344 206 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
protein polymerization GO:0051258 57 0.011
regulation of secretion GO:0051046 274 0.011
negative regulation of organelle organization GO:0010639 90 0.011
carbohydrate homeostasis GO:0033500 128 0.011
forebrain development GO:0030900 302 0.011
regulation of actin filament based process GO:0032970 99 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
cellular chemical homeostasis GO:0055082 215 0.010
chemotaxis GO:0006935 247 0.010
macromolecule methylation GO:0043414 120 0.010
calcium ion transport GO:0006816 159 0.010
dephosphorylation GO:0016311 129 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
lateral inhibition GO:0046331 1 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
organ growth GO:0035265 117 0.010
asymmetric stem cell division GO:0098722 3 0.010
fertilization GO:0009566 127 0.010
cell fate commitment GO:0045165 210 0.010
glycosylation GO:0070085 62 0.010
carboxylic acid transport GO:0046942 100 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
appendage development GO:0048736 166 0.010
regulation of peptidase activity GO:0052547 96 0.010
epithelial cell development GO:0002064 159 0.010
t cell differentiation GO:0030217 174 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
cognition GO:0050890 149 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
metal ion homeostasis GO:0055065 189 0.010
divalent inorganic cation transport GO:0072511 178 0.010
positive regulation of immune effector process GO:0002699 107 0.010

Thop1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013