Mus musculus

0 known processes

Dhx8

DEAH (Asp-Glu-Ala-His) box polypeptide 8

(Aliases: MGC31290,mKIAA4096,Ddx8,mDEAH6,KIAA4096)

Dhx8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
myeloid cell differentiation GO:0030099 233 0.081
mrna metabolic process GO:0016071 84 0.055
Yeast Fly
protein modification by small protein conjugation or removal GO:0070647 207 0.054
cellular ketone metabolic process GO:0042180 84 0.050
protein modification by small protein conjugation GO:0032446 187 0.049
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.049
apoptotic signaling pathway GO:0097190 306 0.046
rna processing GO:0006396 105 0.043
Yeast Fly
regulation of cellular ketone metabolic process GO:0010565 66 0.043
regulation of cellular amine metabolic process GO:0033238 20 0.041
cellular amino acid metabolic process GO:0006520 103 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
cellular amine metabolic process GO:0044106 44 0.038
positive regulation of protein modification process GO:0031401 299 0.037
dephosphorylation GO:0016311 129 0.037
regulation of organelle organization GO:0033043 289 0.036
mitotic cell cycle GO:0000278 195 0.034
modification dependent macromolecule catabolic process GO:0043632 133 0.034
protein ubiquitination GO:0016567 171 0.034
cytoplasmic transport GO:0016482 234 0.032
modification dependent protein catabolic process GO:0019941 133 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
amine metabolic process GO:0009308 45 0.031
homeostasis of number of cells GO:0048872 210 0.030
regulation of apoptotic signaling pathway GO:2001233 197 0.030
rna splicing GO:0008380 54 0.029
Yeast Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.028
regulation of cell cycle GO:0051726 281 0.028
negative regulation of intracellular signal transduction GO:1902532 167 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
macromolecule catabolic process GO:0009057 281 0.028
regulation of myeloid cell differentiation GO:0045637 96 0.028
histone h4 k16 acetylation GO:0043984 3 0.027
cellular response to dna damage stimulus GO:0006974 207 0.027
positive regulation of protein phosphorylation GO:0001934 242 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
Yeast
myeloid cell homeostasis GO:0002262 114 0.025
dna metabolic process GO:0006259 303 0.025
immune effector process GO:0002252 321 0.025
negative regulation of immune system process GO:0002683 209 0.024
membrane organization GO:0061024 245 0.024
covalent chromatin modification GO:0016569 163 0.024
peptidyl amino acid modification GO:0018193 336 0.023
erythrocyte differentiation GO:0030218 88 0.022
histone lysine methylation GO:0034968 50 0.022
positive regulation of dna templated transcription elongation GO:0032786 2 0.022
cell division GO:0051301 120 0.022
macromolecule methylation GO:0043414 120 0.022
stem cell differentiation GO:0048863 268 0.022
protein maturation GO:0051604 176 0.022
lymphocyte differentiation GO:0030098 242 0.022
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.021
Yeast Fly
intracellular mrna localization GO:0008298 4 0.021
cellular response to molecule of bacterial origin GO:0071219 83 0.021
cellular response to cytokine stimulus GO:0071345 189 0.021
digestive system development GO:0055123 200 0.021
histone modification GO:0016570 159 0.021
regulation of mapk cascade GO:0043408 248 0.021
intracellular protein transport GO:0006886 204 0.021
transdifferentiation GO:0060290 1 0.021
protein catabolic process GO:0030163 221 0.021
chromatin organization GO:0006325 206 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
Yeast
stem cell development GO:0048864 219 0.020
lipid biosynthetic process GO:0008610 179 0.020
regulation of protein catabolic process GO:0042176 108 0.020
regulation of cell division GO:0051302 76 0.020
mrna processing GO:0006397 63 0.019
Yeast Fly
protein processing GO:0016485 163 0.019
regulation of cell activation GO:0050865 289 0.019
mapk cascade GO:0000165 281 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
mrna splicing via spliceosome GO:0000398 43 0.019
Yeast Fly
small gtpase mediated signal transduction GO:0007264 97 0.018
tube formation GO:0035148 140 0.018
regulation of protein processing GO:0070613 96 0.018
germ cell development GO:0007281 185 0.018
Fly
cell type specific apoptotic process GO:0097285 268 0.018
leukocyte differentiation GO:0002521 342 0.018
neural tube development GO:0021915 160 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
histone h3 k4 methylation GO:0051568 23 0.018
regulation of mitotic cell cycle GO:0007346 126 0.017
endomembrane system organization GO:0010256 147 0.017
response to lipopolysaccharide GO:0032496 128 0.017
spermatogenesis GO:0007283 284 0.017
Fly
learning or memory GO:0007611 148 0.017
protein localization to organelle GO:0033365 185 0.017
protein methylation GO:0006479 81 0.017
positive regulation of cell death GO:0010942 224 0.017
negative regulation of proteolysis GO:0045861 74 0.017
mitotic cell cycle process GO:1903047 159 0.017
blastocyst development GO:0001824 80 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
negative regulation of myeloid cell differentiation GO:0045638 38 0.017
response to growth factor GO:0070848 198 0.017
positive regulation of lymphocyte differentiation GO:0045621 61 0.016
organophosphate catabolic process GO:0046434 232 0.016
Yeast
regulation of cellular catabolic process GO:0031329 242 0.016
molting cycle GO:0042303 90 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
methylation GO:0032259 134 0.016
cytokine mediated signaling pathway GO:0019221 115 0.016
regulation of chromosome organization GO:0033044 83 0.016
morphogenesis of embryonic epithelium GO:0016331 159 0.016
skeletal system development GO:0001501 356 0.016
camera type eye development GO:0043010 266 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
Yeast
purine ribonucleoside catabolic process GO:0046130 205 0.015
Yeast
cellularization GO:0007349 1 0.015
cellular protein complex assembly GO:0043623 116 0.015
cellular response to lipid GO:0071396 145 0.015
organelle fission GO:0048285 170 0.015
protein alkylation GO:0008213 81 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
carbohydrate metabolic process GO:0005975 230 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
Yeast
nucleotide catabolic process GO:0009166 217 0.015
Yeast
negative regulation of cell proliferation GO:0008285 296 0.015
nitrogen compound transport GO:0071705 271 0.014
regulation of proteolysis GO:0030162 164 0.014
histone methylation GO:0016571 71 0.014
mitotic cytokinesis GO:0000281 4 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
nucleobase containing small molecule metabolic process GO:0055086 352 0.014
Yeast
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
digestive tract development GO:0048565 190 0.014
dna endoreduplication GO:0042023 4 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
positive regulation of chromosome segregation GO:0051984 4 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
Yeast
ras protein signal transduction GO:0007265 77 0.014
tube closure GO:0060606 91 0.014
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.014
protein localization to membrane GO:0072657 108 0.014
regulation of protein localization GO:0032880 231 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
macromolecular complex disassembly GO:0032984 43 0.013
Yeast
cytokine production GO:0001816 319 0.013
positive regulation of nervous system development GO:0051962 221 0.013
blastocyst growth GO:0001832 23 0.013
maintenance of location GO:0051235 89 0.013
positive regulation of defense response GO:0031349 124 0.013
regulation of nuclear division GO:0051783 56 0.013
negative regulation of organelle organization GO:0010639 90 0.013
response to oxygen levels GO:0070482 62 0.013
aromatic compound catabolic process GO:0019439 286 0.013
Yeast
purine nucleotide metabolic process GO:0006163 302 0.013
Yeast
positive regulation of programmed cell death GO:0043068 218 0.013
response to organic cyclic compound GO:0014070 198 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
regulation of cellular protein catabolic process GO:1903362 61 0.013
ossification GO:0001503 216 0.012
cell adhesion GO:0007155 329 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
Yeast
heterocycle catabolic process GO:0046700 280 0.012
Yeast
inflammatory response GO:0006954 244 0.012
regulation of protein complex assembly GO:0043254 83 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
regulation of cellular response to stress GO:0080135 159 0.012
cellular homeostasis GO:0019725 240 0.012
blood circulation GO:0008015 195 0.012
cell cycle g1 s phase transition GO:0044843 57 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
Yeast
dna alkylation GO:0006305 43 0.012
regulation of protein maturation GO:1903317 96 0.012
purine containing compound catabolic process GO:0072523 213 0.012
Yeast
nuclear division GO:0000280 158 0.012
gland development GO:0048732 330 0.012
g1 s transition of mitotic cell cycle GO:0000082 57 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
negative regulation of protein catabolic process GO:0042177 36 0.012
purine containing compound metabolic process GO:0072521 311 0.012
Yeast
positive regulation of cell development GO:0010720 237 0.012
regulation of hormone levels GO:0010817 211 0.012
peptidyl lysine modification GO:0018205 77 0.012
cellular protein catabolic process GO:0044257 155 0.012
negative regulation of dna replication GO:0008156 4 0.011
cellular protein complex disassembly GO:0043624 36 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.011
muscle cell differentiation GO:0042692 261 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
Yeast
response to organonitrogen compound GO:0010243 246 0.011
cognition GO:0050890 149 0.011
t cell activation GO:0042110 289 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
gtp metabolic process GO:0046039 144 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
regulation of proteasomal protein catabolic process GO:0061136 46 0.011
chromosome organization involved in meiosis GO:0070192 39 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
digestive tract morphogenesis GO:0048546 147 0.011
ncrna 3 end processing GO:0043628 2 0.011
regulation of cell adhesion GO:0030155 154 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
blood vessel morphogenesis GO:0048514 285 0.011
response to acid chemical GO:0001101 111 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
positive regulation of cell activation GO:0050867 158 0.011
ribose phosphate metabolic process GO:0019693 291 0.011
Yeast
epithelial tube formation GO:0072175 130 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
primary neural tube formation GO:0014020 95 0.011
response to starvation GO:0042594 65 0.011
negative regulation of molecular function GO:0044092 258 0.011
locomotory behavior GO:0007626 195 0.011
actin cytoskeleton organization GO:0030036 220 0.011
transmembrane transport GO:0055085 412 0.011
endocytosis GO:0006897 168 0.011
rna localization GO:0006403 23 0.011
neural tube formation GO:0001841 108 0.011
regulation of transferase activity GO:0051338 263 0.011
regulation of membrane potential GO:0042391 192 0.011
forebrain development GO:0030900 302 0.011
neuron death GO:0070997 154 0.011
habituation GO:0046959 3 0.011
response to extracellular stimulus GO:0009991 127 0.011
protein targeting GO:0006605 143 0.010
regulation of homeostatic process GO:0032844 182 0.010
sensory perception GO:0007600 245 0.010
nuclear transport GO:0051169 139 0.010
negative regulation of protein maturation GO:1903318 79 0.010
regulation of cell projection organization GO:0031344 206 0.010
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.010
response to oxidative stress GO:0006979 123 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
development of primary sexual characteristics GO:0045137 143 0.010
leukocyte mediated immunity GO:0002443 174 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
Yeast
positive regulation of leukocyte differentiation GO:1902107 86 0.010
meiotic cell cycle GO:0051321 122 0.010
regulation of response to wounding GO:1903034 189 0.010

Dhx8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.053
retinal degeneration DOID:8466 0 0.053
sensory system disease DOID:0050155 0 0.053
disease of anatomical entity DOID:7 0 0.053
eye and adnexa disease DOID:1492 0 0.053
nervous system disease DOID:863 0 0.053
eye disease DOID:5614 0 0.053
retinitis pigmentosa DOID:10584 0 0.040
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.013
immune system disease DOID:2914 0 0.012
organ system cancer DOID:0050686 0 0.011