Mus musculus

52 known processes

Xpa

xeroderma pigmentosum, complementation group A

(Aliases: AI573865,Xpac)

Xpa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intra s dna damage checkpoint GO:0031573 4 0.928
cellular response to dna damage stimulus GO:0006974 207 0.892
dna metabolic process GO:0006259 303 0.827
response to uv GO:0009411 44 0.746
response to radiation GO:0009314 165 0.716
dna repair GO:0006281 107 0.662
negative regulation of phosphorylation GO:0042326 166 0.365
response to uv b GO:0010224 5 0.361
regulation of cell cycle GO:0051726 281 0.335
negative regulation of cell cycle GO:0045786 123 0.330
cell cycle checkpoint GO:0000075 47 0.322
regulation of transferase activity GO:0051338 263 0.297
apoptotic signaling pathway GO:0097190 306 0.260
regulation of kinase activity GO:0043549 249 0.246
transmission of nerve impulse GO:0019226 76 0.229
cellular macromolecule catabolic process GO:0044265 206 0.229
ensheathment of neurons GO:0007272 76 0.221
positive regulation of cell death GO:0010942 224 0.221
nucleotide excision repair GO:0006289 13 0.218
negative regulation of cellular protein metabolic process GO:0032269 247 0.213
regulation of protein kinase activity GO:0045859 232 0.211
regulation of membrane potential GO:0042391 192 0.206
mitotic cell cycle arrest GO:0071850 4 0.202
regulation of mitotic cell cycle phase transition GO:1901990 73 0.202
negative regulation of protein phosphorylation GO:0001933 126 0.194
leukocyte differentiation GO:0002521 342 0.188
purine ribonucleoside catabolic process GO:0046130 205 0.187
lymphocyte differentiation GO:0030098 242 0.181
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.178
response to x ray GO:0010165 11 0.175
glycosyl compound metabolic process GO:1901657 246 0.175
organonitrogen compound catabolic process GO:1901565 264 0.174
purine nucleoside triphosphate catabolic process GO:0009146 203 0.173
negative regulation of mammary gland epithelial cell proliferation GO:0033600 3 0.171
cation transport GO:0006812 399 0.168
regulation of mapk cascade GO:0043408 248 0.164
response to light stimulus GO:0009416 135 0.162
t cell activation GO:0042110 289 0.159
neuronal action potential GO:0019228 54 0.158
multicellular organismal signaling GO:0035637 91 0.154
negative regulation of mitotic cell cycle GO:0045930 58 0.154
negative regulation of phosphorus metabolic process GO:0010563 184 0.153
nucleobase containing small molecule metabolic process GO:0055086 352 0.152
intrinsic apoptotic signaling pathway GO:0097193 132 0.148
regulation of cell cycle phase transition GO:1901987 77 0.144
nucleotide metabolic process GO:0009117 332 0.144
nucleoside phosphate metabolic process GO:0006753 338 0.141
carbohydrate derivative catabolic process GO:1901136 231 0.140
cellular amine metabolic process GO:0044106 44 0.131
action potential GO:0001508 78 0.131
negative regulation of cell cycle phase transition GO:1901988 48 0.131
purine ribonucleoside metabolic process GO:0046128 241 0.128
regulation of cellular ketone metabolic process GO:0010565 66 0.124
cellular amino acid metabolic process GO:0006520 103 0.123
ribonucleotide catabolic process GO:0009261 208 0.123
cell cycle arrest GO:0007050 37 0.122
regulation of hydrolase activity GO:0051336 246 0.121
positive regulation of apoptotic process GO:0043065 217 0.120
immune effector process GO:0002252 321 0.119
nucleoside triphosphate metabolic process GO:0009141 230 0.119
muscle tissue development GO:0060537 308 0.119
regulation of mitotic cell cycle GO:0007346 126 0.116
negative regulation of leukocyte differentiation GO:1902106 51 0.114
oxidation reduction process GO:0055114 342 0.114
aromatic compound catabolic process GO:0019439 286 0.113
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.111
cell adhesion GO:0007155 329 0.109
forebrain development GO:0030900 302 0.109
positive regulation of programmed cell death GO:0043068 218 0.109
negative regulation of lymphocyte activation GO:0051250 91 0.109
neuron apoptotic process GO:0051402 142 0.109
ribonucleotide metabolic process GO:0009259 291 0.108
negative regulation of growth GO:0045926 99 0.108
negative regulation of phosphate metabolic process GO:0045936 184 0.107
purine nucleoside metabolic process GO:0042278 241 0.106
purine containing compound catabolic process GO:0072523 213 0.105
protein modification by small protein conjugation or removal GO:0070647 207 0.104
regulation of cellular catabolic process GO:0031329 242 0.104
negative regulation of cell growth GO:0030308 44 0.104
ribonucleoside catabolic process GO:0042454 206 0.104
regulation of cell cycle process GO:0010564 160 0.103
purine ribonucleotide catabolic process GO:0009154 208 0.100
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.100
regulation of reactive oxygen species metabolic process GO:2000377 40 0.099
epithelial cell proliferation GO:0050673 174 0.099
regulation of protein serine threonine kinase activity GO:0071900 157 0.099
nucleoside phosphate catabolic process GO:1901292 222 0.098
purine nucleotide catabolic process GO:0006195 211 0.095
response to oxidative stress GO:0006979 123 0.095
regulation of cell growth GO:0001558 91 0.094
negative regulation of immune system process GO:0002683 209 0.092
reactive oxygen species metabolic process GO:0072593 84 0.092
organic cyclic compound catabolic process GO:1901361 295 0.092
kidney development GO:0001822 213 0.091
regulation of leukocyte differentiation GO:1902105 159 0.091
cellular ketone metabolic process GO:0042180 84 0.089
regulation of cell activation GO:0050865 289 0.089
purine nucleotide metabolic process GO:0006163 302 0.089
nucleoside catabolic process GO:0009164 206 0.089
male sex differentiation GO:0046661 109 0.088
negative regulation of protein modification process GO:0031400 163 0.087
heterocycle catabolic process GO:0046700 280 0.086
organophosphate catabolic process GO:0046434 232 0.085
purine nucleoside triphosphate metabolic process GO:0009144 226 0.084
epithelial tube morphogenesis GO:0060562 303 0.084
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.083
nucleotide catabolic process GO:0009166 217 0.083
macromolecule catabolic process GO:0009057 281 0.082
purine containing compound metabolic process GO:0072521 311 0.082
regulation of cellular amino acid metabolic process GO:0006521 5 0.081
dna integrity checkpoint GO:0031570 28 0.081
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.081
mapk cascade GO:0000165 281 0.080
nucleoside metabolic process GO:0009116 246 0.080
myeloid cell differentiation GO:0030099 233 0.079
homeostasis of number of cells GO:0048872 210 0.079
response to organonitrogen compound GO:0010243 246 0.079
glycosyl compound catabolic process GO:1901658 206 0.079
ubiquitin dependent protein catabolic process GO:0006511 129 0.078
development of primary male sexual characteristics GO:0046546 88 0.078
hematopoietic progenitor cell differentiation GO:0002244 143 0.078
somatic cell dna recombination GO:0016444 51 0.076
stem cell differentiation GO:0048863 268 0.075
response to ionizing radiation GO:0010212 42 0.073
ribose phosphate metabolic process GO:0019693 291 0.073
cellular nitrogen compound catabolic process GO:0044270 280 0.072
mitotic cell cycle process GO:1903047 159 0.072
ribonucleoside metabolic process GO:0009119 245 0.072
germ cell development GO:0007281 185 0.072
regulation of insulin receptor signaling pathway GO:0046626 21 0.071
myeloid cell homeostasis GO:0002262 114 0.070
ribonucleoside triphosphate metabolic process GO:0009199 220 0.070
stress activated protein kinase signaling cascade GO:0031098 81 0.070
angiogenesis GO:0001525 201 0.069
purine ribonucleotide metabolic process GO:0009150 290 0.069
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.069
nucleoside triphosphate catabolic process GO:0009143 205 0.069
ribonucleoside triphosphate catabolic process GO:0009203 199 0.069
regulation of cohesin localization to chromatin GO:0071922 1 0.069
positive regulation of protein phosphorylation GO:0001934 242 0.068
muscle cell differentiation GO:0042692 261 0.068
rho protein signal transduction GO:0007266 32 0.068
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.068
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.067
glandular epithelial cell differentiation GO:0002067 38 0.067
ras protein signal transduction GO:0007265 77 0.067
regulation of t cell differentiation GO:0045580 83 0.066
neuron death GO:0070997 154 0.066
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 1 0.065
axon ensheathment GO:0008366 76 0.065
regulation of lymphocyte activation GO:0051249 240 0.064
respiratory system development GO:0060541 190 0.064
somite development GO:0061053 81 0.063
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.063
regulation of cellular amine metabolic process GO:0033238 20 0.063
positive regulation of hydrolase activity GO:0051345 148 0.062
protein localization to chromatin GO:0071168 3 0.062
cell type specific apoptotic process GO:0097285 268 0.062
cellular protein catabolic process GO:0044257 155 0.062
protein catabolic process GO:0030163 221 0.062
regulation of autophagy GO:0010506 30 0.061
regulation of t cell activation GO:0050863 170 0.061
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.061
cellular response to growth factor stimulus GO:0071363 197 0.061
cohesin localization to chromatin GO:0071921 1 0.060
developmental maturation GO:0021700 193 0.059
leukocyte proliferation GO:0070661 172 0.059
renal system development GO:0072001 225 0.059
negative regulation of cell cycle process GO:0010948 69 0.059
leukocyte activation involved in immune response GO:0002366 126 0.058
protein maturation GO:0051604 176 0.058
regionalization GO:0003002 337 0.057
negative regulation of protein metabolic process GO:0051248 282 0.056
cell growth GO:0016049 130 0.056
negative regulation of molecular function GO:0044092 258 0.056
response to nutrient levels GO:0031667 109 0.056
dna damage checkpoint GO:0000077 26 0.056
negative regulation of apoptotic signaling pathway GO:2001234 104 0.056
mitotic cell cycle GO:0000278 195 0.055
regulation of lymphocyte differentiation GO:0045619 107 0.055
positive regulation of cellular amine metabolic process GO:0033240 5 0.054
t cell differentiation GO:0030217 174 0.054
mitotic cell cycle checkpoint GO:0007093 31 0.054
negative regulation of kinase activity GO:0033673 81 0.054
b cell activation GO:0042113 161 0.054
negative regulation of lymphocyte differentiation GO:0045620 32 0.054
positive regulation of mapk cascade GO:0043410 170 0.054
branching morphogenesis of an epithelial tube GO:0048754 159 0.053
t cell proliferation GO:0042098 120 0.053
striated muscle tissue development GO:0014706 293 0.053
negative regulation of intracellular signal transduction GO:1902532 167 0.052
regulation of organelle organization GO:0033043 289 0.052
nucleocytoplasmic transport GO:0006913 139 0.052
cellular response to hormone stimulus GO:0032870 150 0.052
pole plasm assembly GO:0007315 2 0.051
cellular response to oxidative stress GO:0034599 76 0.051
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.051
maintenance of location GO:0051235 89 0.051
nitrogen compound transport GO:0071705 271 0.051
cellular response to insulin stimulus GO:0032869 78 0.050
regulation of protein stability GO:0031647 52 0.050
response to oxygen levels GO:0070482 62 0.050
myelination GO:0042552 74 0.050
negative regulation of t cell activation GO:0050868 65 0.049
methylation GO:0032259 134 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
generation of precursor metabolites and energy GO:0006091 103 0.048
regulation of leukocyte proliferation GO:0070663 121 0.048
male gamete generation GO:0048232 285 0.047
blood vessel morphogenesis GO:0048514 285 0.047
negative regulation of neuron death GO:1901215 98 0.047
sensory perception GO:0007600 245 0.047
organelle fission GO:0048285 170 0.047
lymphocyte activation involved in immune response GO:0002285 93 0.046
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.046
positive regulation of kinase activity GO:0033674 155 0.046
multicellular organism growth GO:0035264 161 0.046
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.045
regulation of purine nucleotide metabolic process GO:1900542 169 0.045
cellular response to external stimulus GO:0071496 88 0.045
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.045
guanosine containing compound metabolic process GO:1901068 144 0.045
gtp catabolic process GO:0006184 143 0.045
adaptive immune response GO:0002250 155 0.044
negative regulation of dna replication GO:0008156 4 0.043
positive regulation of protein modification process GO:0031401 299 0.043
regulation of cytoskeleton organization GO:0051493 122 0.043
negative regulation of cell proliferation GO:0008285 296 0.043
response to extracellular stimulus GO:0009991 127 0.043
regulation of protein processing GO:0070613 96 0.043
cell activation involved in immune response GO:0002263 126 0.042
regulation of epithelial cell proliferation GO:0050678 141 0.042
small gtpase mediated signal transduction GO:0007264 97 0.042
morphogenesis of a branching structure GO:0001763 203 0.042
mitotic g1 dna damage checkpoint GO:0031571 4 0.042
negative regulation of dna recombination GO:0045910 13 0.042
skin development GO:0043588 220 0.042
regulation of cysteine type endopeptidase activity GO:2000116 65 0.042
regulation of cellular response to growth factor stimulus GO:0090287 82 0.042
signal transduction involved in dna damage checkpoint GO:0072422 3 0.042
regulation of cellular component biogenesis GO:0044087 181 0.041
extrinsic apoptotic signaling pathway GO:0097191 126 0.041
meiotic cell cycle GO:0051321 122 0.041
peptidyl amino acid modification GO:0018193 336 0.041
negative regulation of cell size GO:0045792 3 0.041
cell cycle g1 s phase transition GO:0044843 57 0.041
digestive tract development GO:0048565 190 0.040
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.040
morphogenesis of embryonic epithelium GO:0016331 159 0.040
signal transduction by p53 class mediator GO:0072331 51 0.040
epidermis development GO:0008544 187 0.040
regulation of timing of cell differentiation GO:0048505 11 0.040
somitogenesis GO:0001756 69 0.040
positive regulation of rho gtpase activity GO:0032321 41 0.040
glial cell differentiation GO:0010001 131 0.039
myeloid leukocyte differentiation GO:0002573 119 0.039
negative regulation of protein processing GO:0010955 79 0.039
respiratory tube development GO:0030323 167 0.039
dna catabolic process endonucleolytic GO:0000737 15 0.039
regulation of actin cytoskeleton organization GO:0032956 84 0.039
ear development GO:0043583 200 0.038
amine metabolic process GO:0009308 45 0.038
erythrocyte differentiation GO:0030218 88 0.038
gtp metabolic process GO:0046039 144 0.038
multicellular organismal homeostasis GO:0048871 164 0.038
regulation of nucleoside metabolic process GO:0009118 130 0.038
cellular response to lipid GO:0071396 145 0.037
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.037
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.037
urogenital system development GO:0001655 261 0.036
somatic diversification of immune receptors via somatic mutation GO:0002566 8 0.036
autophagy GO:0006914 45 0.036
regulation of lymphocyte proliferation GO:0050670 117 0.036
sensory perception of sound GO:0007605 97 0.036
negative regulation of tor signaling GO:0032007 13 0.036
embryonic organ morphogenesis GO:0048562 276 0.036
carbohydrate transport GO:0008643 62 0.036
peptidyl tyrosine modification GO:0018212 145 0.036
cardiocyte differentiation GO:0035051 87 0.035
negative regulation of cellular amine metabolic process GO:0033239 1 0.035
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.035
chemotaxis GO:0006935 247 0.035
regulation of protein catabolic process GO:0042176 108 0.035
cell substrate adhesion GO:0031589 130 0.035
peptidyl tyrosine phosphorylation GO:0018108 143 0.035
monocarboxylic acid metabolic process GO:0032787 191 0.035
response to decreased oxygen levels GO:0036293 59 0.035
actin filament organization GO:0007015 113 0.035
regulation of protein maturation GO:1903317 96 0.035
b cell differentiation GO:0030183 78 0.035
oocyte axis specification GO:0007309 2 0.035
positive regulation of protein kinase activity GO:0045860 144 0.034
hair cycle GO:0042633 90 0.034
negative regulation of cell activation GO:0050866 111 0.034
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.034
immunoglobulin production GO:0002377 73 0.034
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.034
regulation of nucleocytoplasmic transport GO:0046822 73 0.034
modification dependent protein catabolic process GO:0019941 133 0.034
protein kinase b signaling GO:0043491 74 0.034
cilium morphogenesis GO:0060271 102 0.033
single organismal cell cell adhesion GO:0016337 131 0.033
cell division GO:0051301 120 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.033
regulation of neuron apoptotic process GO:0043523 122 0.033
ossification GO:0001503 216 0.033
cellular homeostasis GO:0019725 240 0.033
regulation of cell substrate adhesion GO:0010810 73 0.033
extracellular matrix organization GO:0030198 147 0.032
production of molecular mediator of immune response GO:0002440 103 0.032
negative regulation of protein maturation GO:1903318 79 0.032
positive regulation of cell development GO:0010720 237 0.032
positive regulation of nucleoside metabolic process GO:0045979 91 0.032
modification dependent macromolecule catabolic process GO:0043632 133 0.032
lymphocyte proliferation GO:0046651 164 0.032
lateral inhibition GO:0046331 1 0.031
regulation of cytoplasmic transport GO:1903649 112 0.031
regulation of ras protein signal transduction GO:0046578 114 0.031
regulation of intracellular transport GO:0032386 159 0.031
cytokine production GO:0001816 319 0.031
cellular response to organonitrogen compound GO:0071417 145 0.031
dephosphorylation GO:0016311 129 0.031
b cell mediated immunity GO:0019724 71 0.031
mitotic sister chromatid cohesion GO:0007064 1 0.031
membrane organization GO:0061024 245 0.031
macromolecule methylation GO:0043414 120 0.031
immunoglobulin mediated immune response GO:0016064 69 0.031
response to growth factor GO:0070848 198 0.030
positive regulation of nucleotide catabolic process GO:0030813 88 0.030
regulation of cytokine production GO:0001817 266 0.030
immune response regulating signaling pathway GO:0002764 125 0.030
purine nucleoside catabolic process GO:0006152 205 0.030
potassium ion transport GO:0006813 52 0.030
posttranscriptional regulation of gene expression GO:0010608 155 0.030
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.029
neural tube closure GO:0001843 90 0.029
leukocyte mediated immunity GO:0002443 174 0.029
regulation of actin filament bundle assembly GO:0032231 18 0.029
jnk cascade GO:0007254 72 0.029
glucose import GO:0046323 32 0.029
regulation of cell cycle g1 s phase transition GO:1902806 35 0.029
regulation of cellular component size GO:0032535 121 0.029
b cell activation involved in immune response GO:0002312 50 0.029
neural tube development GO:0021915 160 0.029
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.029
lymphocyte mediated immunity GO:0002449 139 0.029
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.028
atp metabolic process GO:0046034 75 0.028
cell maturation GO:0048469 127 0.028
glucose transport GO:0015758 56 0.028
g protein coupled receptor signaling pathway GO:0007186 243 0.028
embryonic appendage morphogenesis GO:0035113 126 0.028
dna recombination GO:0006310 92 0.028
sensory perception of mechanical stimulus GO:0050954 107 0.028
regulation of homeostatic process GO:0032844 182 0.028
dna catabolic process GO:0006308 19 0.028
inflammatory response GO:0006954 244 0.028
positive regulation of nervous system development GO:0051962 221 0.027
response to reactive oxygen species GO:0000302 56 0.027
somatic diversification of immunoglobulins GO:0016445 43 0.027
regulation of cell adhesion GO:0030155 154 0.027
carbohydrate homeostasis GO:0033500 128 0.027
regulation of proteolysis GO:0030162 164 0.027
nuclear division GO:0000280 158 0.027
ribonucleoside monophosphate metabolic process GO:0009161 80 0.027
regulation of chromosome organization GO:0033044 83 0.027
lung development GO:0030324 164 0.027
cellular lipid metabolic process GO:0044255 323 0.027
regulation of nucleotide metabolic process GO:0006140 169 0.027
tissue homeostasis GO:0001894 115 0.027
regulation of anatomical structure size GO:0090066 178 0.027
cytoplasmic transport GO:0016482 234 0.027
purine nucleoside monophosphate catabolic process GO:0009128 58 0.026
guanosine containing compound catabolic process GO:1901069 144 0.026
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.026
monosaccharide metabolic process GO:0005996 106 0.026
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.026
embryonic limb morphogenesis GO:0030326 126 0.026
digestive system development GO:0055123 200 0.026
positive regulation of nucleotide metabolic process GO:0045981 114 0.026
determination of left right symmetry GO:0007368 80 0.026
cellular response to acid chemical GO:0071229 68 0.026
positive regulation of map kinase activity GO:0043406 84 0.026
response to acid chemical GO:0001101 111 0.026
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.026
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.026
pallium development GO:0021543 120 0.026
anatomical structure homeostasis GO:0060249 145 0.026
regulation of rho protein signal transduction GO:0035023 71 0.026
response to molecule of bacterial origin GO:0002237 143 0.026
g1 s transition of mitotic cell cycle GO:0000082 57 0.026
actin cytoskeleton organization GO:0030036 220 0.026
apoptotic process involved in mammary gland involution GO:0060057 4 0.026
response to endoplasmic reticulum stress GO:0034976 53 0.026
embryonic epithelial tube formation GO:0001838 130 0.026
connective tissue development GO:0061448 179 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.025
t cell differentiation in thymus GO:0033077 77 0.025
positive regulation of cell adhesion GO:0045785 80 0.025
negative regulation of transferase activity GO:0051348 85 0.025
appendage development GO:0048736 166 0.025
defense response to other organism GO:0098542 197 0.025
anion transport GO:0006820 177 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.025
positive regulation of cellular catabolic process GO:0031331 148 0.025
regulation of cellular response to insulin stimulus GO:1900076 30 0.025
positive regulation of transferase activity GO:0051347 167 0.025
regulation of stress activated mapk cascade GO:0032872 69 0.025
regulation of translation GO:0006417 71 0.025
insulin receptor signaling pathway GO:0008286 49 0.025
actin filament bundle assembly GO:0051017 40 0.025
negative regulation of immature t cell proliferation GO:0033087 3 0.025
organophosphate biosynthetic process GO:0090407 122 0.025
notch signaling pathway GO:0007219 71 0.025
oocyte construction GO:0007308 2 0.025
neural tube formation GO:0001841 108 0.024
carbohydrate metabolic process GO:0005975 230 0.024
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.024
negative regulation of neuron apoptotic process GO:0043524 92 0.024
negative regulation of t cell differentiation GO:0045581 23 0.024
b cell proliferation GO:0042100 53 0.024
positive regulation of gtpase activity GO:0043547 85 0.024
positive regulation of leukocyte differentiation GO:1902107 86 0.024
regulation of leukocyte apoptotic process GO:2000106 56 0.024
skeletal system development GO:0001501 356 0.024
camera type eye development GO:0043010 266 0.024
regulation of cell motility GO:2000145 236 0.024
positive regulation of cytokine production GO:0001819 174 0.024
response to lipopolysaccharide GO:0032496 128 0.024
hematopoietic stem cell differentiation GO:0060218 8 0.024
protein ubiquitination GO:0016567 171 0.023
regulation of nucleotide catabolic process GO:0030811 122 0.023
glial cell apoptotic process GO:0034349 3 0.023
morphogenesis of a branching epithelium GO:0061138 193 0.023
hexose metabolic process GO:0019318 98 0.023
response to peptide GO:1901652 136 0.023
regulation of t cell proliferation GO:0042129 92 0.023
regulation of binding GO:0051098 111 0.023
positive regulation of apoptotic signaling pathway GO:2001235 95 0.023
signal transduction involved in cell cycle checkpoint GO:0072395 3 0.023
positive regulation of cellular component biogenesis GO:0044089 94 0.023
cellular response to oxygen levels GO:0071453 20 0.023
cellular response to peptide GO:1901653 92 0.023
spinal cord development GO:0021510 81 0.022
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.022
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 18 0.022
central nervous system neuron differentiation GO:0021953 162 0.022
protein localization to organelle GO:0033365 185 0.022
regulation of stress fiber assembly GO:0051492 15 0.022
limb development GO:0060173 166 0.022
photoreceptor cell maintenance GO:0045494 19 0.022
negative regulation of organ growth GO:0046621 17 0.022
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 9 0.022
gland development GO:0048732 330 0.022
positive regulation of rac protein signal transduction GO:0035022 1 0.022
cellular response to decreased oxygen levels GO:0036294 18 0.022
regulation of tor signaling GO:0032006 17 0.022
cell matrix adhesion GO:0007160 68 0.022
telencephalon development GO:0021537 186 0.022
response to oxygen radical GO:0000305 16 0.022
regulation of jnk cascade GO:0046328 62 0.022
innate immune response GO:0045087 157 0.022
peptidyl lysine modification GO:0018205 77 0.022
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 3 0.021
synaptic transmission GO:0007268 329 0.021
microtubule based process GO:0007017 236 0.021
histone lysine methylation GO:0034968 50 0.021
transmembrane transport GO:0055085 412 0.021
translation GO:0006412 93 0.021
regulation of protein localization GO:0032880 231 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
regulation of defense response GO:0031347 233 0.021
somatic hypermutation of immunoglobulin genes GO:0016446 7 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
activation of immune response GO:0002253 138 0.021
regulation of cellular response to stress GO:0080135 159 0.021
regulation of rho gtpase activity GO:0032319 58 0.021
meiosis i GO:0007127 60 0.021
gliogenesis GO:0042063 141 0.021
hexose transport GO:0008645 56 0.021
cell cell junction organization GO:0045216 72 0.021
mitochondrion organization GO:0007005 134 0.021
stem cell proliferation GO:0072089 117 0.020
positive regulation of apoptotic process involved in morphogenesis GO:1902339 4 0.020
wnt signaling pathway GO:0016055 188 0.020
extracellular structure organization GO:0043062 148 0.020
response to insulin GO:0032868 100 0.020
axonogenesis GO:0007409 274 0.020

Xpa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.050
thoracic cancer DOID:5093 0 0.032
cancer DOID:162 0 0.032
organ system cancer DOID:0050686 0 0.032
disease of metabolism DOID:0014667 0 0.028
disease of anatomical entity DOID:7 0 0.020