Mus musculus

15 known processes

Hsph1

heat shock 105kDa/110kDa protein 1

(Aliases: AI790491,Hsp105,hsp-E7I,Hsp110,105kDa)

Hsph1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein refolding GO:0042026 1 1.000
Yeast
protein localization to mitochondrion GO:0070585 15 0.971
chaperone mediated protein folding GO:0061077 10 0.936
protein targeting to mitochondrion GO:0006626 6 0.910
negative regulation of transposition GO:0010529 2 0.906
protein folding GO:0006457 28 0.895
de novo protein folding GO:0006458 9 0.840
organelle disassembly GO:1903008 2 0.812
regulation of transposition GO:0010528 2 0.793
striated muscle myosin thick filament assembly GO:0071688 1 0.732
negative regulation of inclusion body assembly GO:0090084 1 0.729
positive regulation of cardiac muscle contraction GO:0060452 2 0.711
protein transmembrane transport GO:0071806 8 0.692
response to heat GO:0009408 27 0.687
myosin filament organization GO:0031033 3 0.601
microtubule cytoskeleton organization GO:0000226 157 0.499
macromolecule catabolic process GO:0009057 281 0.485
vesicle uncoating GO:0072319 4 0.473
cellular response to topologically incorrect protein GO:0035967 25 0.445
mitochondrial transport GO:0006839 36 0.436
cell cell recognition GO:0009988 44 0.408
protein modification by small protein conjugation or removal GO:0070647 207 0.382
toxin transport GO:1901998 38 0.371
negative regulation of transferase activity GO:0051348 85 0.365
sperm egg recognition GO:0035036 37 0.351
microtubule based process GO:0007017 236 0.332
transmembrane transport GO:0055085 412 0.330
regulation of circadian sleep wake cycle GO:0042749 3 0.329
response to topologically incorrect protein GO:0035966 25 0.320
regulation of microtubule based process GO:0032886 52 0.271
negative regulation of cellular protein metabolic process GO:0032269 247 0.270
protein localization to nucleus GO:0034504 121 0.265
myosin filament assembly GO:0031034 2 0.244
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.244
positive regulation of striated muscle contraction GO:0045989 3 0.238
cellular response to interleukin 4 GO:0071353 21 0.234
misfolded protein transport GO:0070843 1 0.219
negative regulation of phosphorylation GO:0042326 166 0.218
protein import into nucleus GO:0006606 95 0.215
posttranscriptional regulation of gene expression GO:0010608 155 0.215
circadian sleep wake cycle GO:0042745 5 0.208
muscle cell differentiation GO:0042692 261 0.198
establishment of protein localization to mitochondrion GO:0072655 11 0.194
stress granule disassembly GO:0035617 2 0.190
single organism nuclear import GO:1902593 95 0.183
jnk cascade GO:0007254 72 0.181
protein import GO:0017038 101 0.175
regulation of protein transport GO:0051223 163 0.172
regulation of establishment of protein localization GO:0070201 181 0.170
protein targeting to er GO:0045047 2 0.167
regulation of inclusion body assembly GO:0090083 1 0.162
peptidyl proline hydroxylation GO:0019511 3 0.156
inclusion body assembly GO:0070841 3 0.153
ribonucleoprotein complex disassembly GO:0032988 3 0.147
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.145
posttranscriptional gene silencing by rna GO:0035194 10 0.145
detection of stimulus GO:0051606 84 0.142
single fertilization GO:0007338 82 0.142
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.142
establishment of protein localization to organelle GO:0072594 118 0.140
negative regulation of protein phosphorylation GO:0001933 126 0.132
purine containing compound catabolic process GO:0072523 213 0.125
Yeast
spindle assembly involved in mitosis GO:0090307 4 0.124
regulation of protein serine threonine kinase activity GO:0071900 157 0.124
cellular response to heat GO:0034605 15 0.123
positive regulation of protein import into nucleus translocation GO:0033160 1 0.123
regulation of transferase activity GO:0051338 263 0.122
protein localization to organelle GO:0033365 185 0.119
negative regulation of map kinase activity GO:0043407 34 0.118
regulation of intracellular transport GO:0032386 159 0.116
rna dependent dna replication GO:0006278 3 0.115
dna metabolic process GO:0006259 303 0.106
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.105
peptidyl proline modification GO:0018208 6 0.104
regulation of protein import into nucleus translocation GO:0033158 2 0.103
nucleoside metabolic process GO:0009116 246 0.101
Yeast
regulation of cytoskeleton organization GO:0051493 122 0.099
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.099
cellular macromolecule catabolic process GO:0044265 206 0.098
intracellular protein transport GO:0006886 204 0.096
response to organonitrogen compound GO:0010243 246 0.095
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.094
pore complex assembly GO:0046931 3 0.093
heterocycle catabolic process GO:0046700 280 0.093
Yeast
positive regulation of apoptotic process GO:0043065 217 0.092
response to osmotic stress GO:0006970 21 0.090
sperm motility GO:0030317 47 0.090
clathrin coat disassembly GO:0072318 3 0.088
actin cytoskeleton organization GO:0030036 220 0.088
cellular component assembly involved in morphogenesis GO:0010927 139 0.088
ribonucleoside triphosphate catabolic process GO:0009203 199 0.087
Yeast
telomere maintenance via telomerase GO:0007004 1 0.087
cell recognition GO:0008037 83 0.086
amine metabolic process GO:0009308 45 0.086
protein modification by small protein conjugation GO:0032446 187 0.085
regulation of cell size GO:0008361 72 0.082
positive regulation of cell death GO:0010942 224 0.082
regulation of cytoplasmic transport GO:1903649 112 0.081
gene silencing by rna GO:0031047 19 0.080
response to metal ion GO:0010038 47 0.080
cellular protein complex assembly GO:0043623 116 0.080
neuron death GO:0070997 154 0.080
intracellular receptor signaling pathway GO:0030522 74 0.080
regulation of protein localization GO:0032880 231 0.079
negative regulation of protein metabolic process GO:0051248 282 0.079
nucleoside phosphate metabolic process GO:0006753 338 0.079
Yeast
regulation of anatomical structure size GO:0090066 178 0.078
organelle assembly GO:0070925 177 0.078
dna replication GO:0006260 52 0.077
response to temperature stimulus GO:0009266 55 0.077
fertilization GO:0009566 127 0.075
atp catabolic process GO:0006200 55 0.074
Yeast
regulation of circadian rhythm GO:0042752 58 0.074
reactive nitrogen species metabolic process GO:2001057 0 0.074
negative regulation of phosphorus metabolic process GO:0010563 184 0.074
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.073
nuclear import GO:0051170 95 0.073
cellular nitrogen compound catabolic process GO:0044270 280 0.073
Yeast
regulation of cellular response to stress GO:0080135 159 0.071
regulation of protein kinase activity GO:0045859 232 0.071
negative regulation of viral genome replication GO:0045071 10 0.070
cell type specific apoptotic process GO:0097285 268 0.070
reactive oxygen species biosynthetic process GO:1903409 8 0.069
regulation of kinase activity GO:0043549 249 0.069
nucleocytoplasmic transport GO:0006913 139 0.068
nucleoside phosphate catabolic process GO:1901292 222 0.068
Yeast
rna interference GO:0016246 2 0.067
establishment of protein localization to endoplasmic reticulum GO:0072599 2 0.067
positive regulation of dna replication GO:0045740 9 0.066
negative regulation of jun kinase activity GO:0043508 9 0.066
protein catabolic process GO:0030163 221 0.065
mitochondrion organization GO:0007005 134 0.065
cellular response to cytokine stimulus GO:0071345 189 0.064
cellular protein catabolic process GO:0044257 155 0.064
ribonucleoside metabolic process GO:0009119 245 0.062
Yeast
ribonucleoprotein complex subunit organization GO:0071826 28 0.062
negative regulation of kinase activity GO:0033673 81 0.060
nuclear transport GO:0051169 139 0.059
regulation of jun kinase activity GO:0043506 40 0.059
snorna metabolic process GO:0016074 1 0.058
organic cyclic compound catabolic process GO:1901361 295 0.058
Yeast
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.057
regulation of cell cycle GO:0051726 281 0.057
regulation of cell projection organization GO:0031344 206 0.057
response to peptide GO:1901652 136 0.057
aromatic compound catabolic process GO:0019439 286 0.056
Yeast
negative regulation of cell proliferation GO:0008285 296 0.055
actomyosin structure organization GO:0031032 56 0.053
nucleobase containing small molecule metabolic process GO:0055086 352 0.053
Yeast
ribonucleoside monophosphate catabolic process GO:0009158 57 0.053
Yeast
cellular amine metabolic process GO:0044106 44 0.053
negative regulation of protein modification process GO:0031400 163 0.053
protein targeting GO:0006605 143 0.052
telomere maintenance GO:0000723 19 0.052
microtubule organizing center organization GO:0031023 28 0.051
purine ribonucleotide catabolic process GO:0009154 208 0.051
Yeast
positive regulation of protein transport GO:0051222 93 0.050
cellular amino acid metabolic process GO:0006520 103 0.050
striated muscle contraction GO:0006941 45 0.050
cardiac muscle tissue development GO:0048738 130 0.050
protein hydroxylation GO:0018126 4 0.049
purine nucleoside metabolic process GO:0042278 241 0.049
Yeast
response to interleukin 4 GO:0070670 23 0.049
circadian behavior GO:0048512 13 0.049
regulation of jnk cascade GO:0046328 62 0.048
regulation of chromosome organization GO:0033044 83 0.047
regulation of protein targeting GO:1903533 61 0.047
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.046
protein complex disassembly GO:0043241 40 0.046
regulation of microtubule cytoskeleton organization GO:0070507 37 0.046
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.045
gonad development GO:0008406 141 0.045
carbohydrate derivative catabolic process GO:1901136 231 0.044
Yeast
proteasome assembly GO:0043248 1 0.043
nucleoside triphosphate catabolic process GO:0009143 205 0.043
Yeast
organonitrogen compound catabolic process GO:1901565 264 0.043
Yeast
myeloid leukocyte activation GO:0002274 83 0.043
protein ubiquitination GO:0016567 171 0.043
skeletal muscle thin filament assembly GO:0030240 2 0.042
glycosyl compound catabolic process GO:1901658 206 0.042
Yeast
regulation of protein ubiquitination GO:0031396 52 0.041
regulation of nucleocytoplasmic transport GO:0046822 73 0.041
nucleoside catabolic process GO:0009164 206 0.041
Yeast
purine nucleoside triphosphate metabolic process GO:0009144 226 0.041
Yeast
cytoplasmic transport GO:0016482 234 0.041
oocyte anterior posterior axis specification GO:0007314 2 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.041
Yeast
glycosyl compound metabolic process GO:1901657 246 0.041
Yeast
androgen receptor signaling pathway GO:0030521 8 0.041
respiratory system development GO:0060541 190 0.040
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.040
Yeast
regulation of protein import into nucleus GO:0042306 52 0.040
actin filament organization GO:0007015 113 0.039
regulation of reactive oxygen species metabolic process GO:2000377 40 0.039
monocarboxylic acid metabolic process GO:0032787 191 0.038
positive regulation of muscle contraction GO:0045933 10 0.038
cajal body organization GO:0030576 1 0.038
positive regulation of hydrolase activity GO:0051345 148 0.037
ribonucleotide metabolic process GO:0009259 291 0.037
Yeast
purine ribonucleotide metabolic process GO:0009150 290 0.036
Yeast
striated muscle tissue development GO:0014706 293 0.036
nitric oxide metabolic process GO:0046209 25 0.036
response to unfolded protein GO:0006986 21 0.036
muscle contraction GO:0006936 101 0.035
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.035
regulation of cellular component size GO:0032535 121 0.034
positive regulation of cytoplasmic transport GO:1903651 40 0.034
nucleoside monophosphate metabolic process GO:0009123 85 0.034
Yeast
skeletal muscle myosin thick filament assembly GO:0030241 1 0.034
male gamete generation GO:0048232 285 0.034
protein targeting to membrane GO:0006612 20 0.034
regulation of mrna metabolic process GO:1903311 43 0.034
regulation of neuron apoptotic process GO:0043523 122 0.033
fibril organization GO:0097435 2 0.032
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
Yeast
regulation of cell projection assembly GO:0060491 38 0.032
endoplasmic reticulum unfolded protein response GO:0030968 19 0.032
centrosome cycle GO:0007098 23 0.031
positive regulation of protein localization to nucleus GO:1900182 30 0.031
rna splicing GO:0008380 54 0.031
rhythmic process GO:0048511 174 0.031
negative regulation of neuron death GO:1901215 98 0.030
regulation of muscle contraction GO:0006937 49 0.030
cellular response to calcium ion GO:0071277 14 0.030
striated muscle cell development GO:0055002 125 0.030
muscle tissue development GO:0060537 308 0.030
regulation of map kinase activity GO:0043405 120 0.030
purine nucleotide metabolic process GO:0006163 302 0.030
Yeast
respiratory tube development GO:0030323 167 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
negative regulation of molecular function GO:0044092 258 0.029
regulation of intracellular protein transport GO:0033157 82 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
regulation of dna replication GO:0006275 17 0.028
centriole assembly GO:0098534 6 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
receptor mediated endocytosis GO:0006898 51 0.028
nucleoside monophosphate catabolic process GO:0009125 59 0.028
Yeast
circadian rhythm GO:0007623 114 0.028
spermatogenesis GO:0007283 284 0.028
posttranscriptional gene silencing GO:0016441 10 0.027
mrna metabolic process GO:0016071 84 0.027
macromolecular complex disassembly GO:0032984 43 0.027
dendrite development GO:0016358 115 0.027
organophosphate catabolic process GO:0046434 232 0.027
Yeast
regulation of tube size GO:0035150 57 0.027
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.026
Yeast
regulation of cellular response to oxidative stress GO:1900407 19 0.026
ribonucleoside monophosphate metabolic process GO:0009161 80 0.026
Yeast
nucleotide catabolic process GO:0009166 217 0.026
Yeast
cellular response to cadmium ion GO:0071276 3 0.026
regulation of homeostatic process GO:0032844 182 0.026
purine nucleoside monophosphate catabolic process GO:0009128 58 0.026
Yeast
binding of sperm to zona pellucida GO:0007339 34 0.026
regulation of neuron projection development GO:0010975 169 0.026
response to calcium ion GO:0051592 20 0.025
neuron recognition GO:0008038 25 0.025
regulation of cellular catabolic process GO:0031329 242 0.025
extracellular matrix organization GO:0030198 147 0.025
misfolded or incompletely synthesized protein catabolic process GO:0006515 4 0.025
cellular protein complex disassembly GO:0043624 36 0.024
regulation of ion transport GO:0043269 215 0.024
nuclear division GO:0000280 158 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.024
Yeast
purine ribonucleoside catabolic process GO:0046130 205 0.024
Yeast
rna splicing via transesterification reactions GO:0000375 43 0.024
positive regulation of t cell activation GO:0050870 101 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
positive regulation of adaptive immune response GO:0002821 61 0.023
regulation of endopeptidase activity GO:0052548 89 0.023
anatomical structure homeostasis GO:0060249 145 0.023
ribose phosphate metabolic process GO:0019693 291 0.023
Yeast
ribonucleoside catabolic process GO:0042454 206 0.022
Yeast
positive regulation of kinase activity GO:0033674 155 0.022
cardiac muscle cell differentiation GO:0055007 69 0.022
cardiac muscle contraction GO:0060048 32 0.022
mapk cascade GO:0000165 281 0.022
regulation of peptidase activity GO:0052547 96 0.022
oxidation reduction process GO:0055114 342 0.022
regulation of neurotransmitter levels GO:0001505 87 0.022
neuron apoptotic process GO:0051402 142 0.022
positive regulation of protein import into nucleus GO:0042307 26 0.022
purine nucleotide catabolic process GO:0006195 211 0.022
Yeast
positive regulation of programmed cell death GO:0043068 218 0.021
purine nucleoside monophosphate metabolic process GO:0009126 81 0.021
Yeast
urogenital system development GO:0001655 261 0.021
sensory perception GO:0007600 245 0.021
ras protein signal transduction GO:0007265 77 0.021
oocyte differentiation GO:0009994 35 0.021
negative regulation of cell development GO:0010721 169 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
establishment of protein localization to membrane GO:0090150 54 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
Yeast
purine nucleoside catabolic process GO:0006152 205 0.021
Yeast
muscle system process GO:0003012 141 0.021
sensory perception of light stimulus GO:0050953 54 0.020
translational initiation GO:0006413 24 0.020
rna processing GO:0006396 105 0.020
regulation of hydrolase activity GO:0051336 246 0.020
protein import into nucleus translocation GO:0000060 12 0.020
response to organic cyclic compound GO:0014070 198 0.020
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.020
lymphocyte activation involved in immune response GO:0002285 93 0.020
protein export from nucleus GO:0006611 20 0.020
substantia nigra development GO:0021762 2 0.020
gene silencing GO:0016458 38 0.020
response to oxygen levels GO:0070482 62 0.019
negative regulation of neuron apoptotic process GO:0043524 92 0.019
response to nutrient levels GO:0031667 109 0.019
skin development GO:0043588 220 0.019
development of primary sexual characteristics GO:0045137 143 0.019
cellular ketone metabolic process GO:0042180 84 0.019
positive regulation of intracellular transport GO:0032388 70 0.019
positive regulation of lamellipodium organization GO:1902745 3 0.019
positive regulation of chromosome organization GO:2001252 33 0.019
developmental maturation GO:0021700 193 0.019
positive regulation of homeostatic process GO:0032846 64 0.019
nitric oxide biosynthetic process GO:0006809 25 0.019
protein localization to membrane GO:0072657 108 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.018
protein localization to chromosome centromeric region GO:0071459 1 0.018
regulation of nitric oxide biosynthetic process GO:0045428 18 0.018
positive regulation of intracellular protein transport GO:0090316 42 0.018
regulation of action potential GO:0098900 4 0.018
response to inorganic substance GO:0010035 96 0.018
male courtship behavior GO:0008049 2 0.018
adaptive immune response GO:0002250 155 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
Yeast
proteasomal protein catabolic process GO:0010498 98 0.018
intracellular mrna localization GO:0008298 4 0.018
mitotic spindle organization GO:0007052 10 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.017
midgut development GO:0007494 4 0.017
primary mirna processing GO:0031053 1 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
nucleus organization GO:0006997 45 0.017
positive regulation of cellular component biogenesis GO:0044089 94 0.017
regulation of angiogenesis GO:0045765 81 0.017
regulation of organelle organization GO:0033043 289 0.017
synaptic transmission GO:0007268 329 0.017
nitrogen compound transport GO:0071705 271 0.017
positive regulation of cell projection organization GO:0031346 95 0.017
peptidyl amino acid modification GO:0018193 336 0.017
regulation of metal ion transport GO:0010959 106 0.017
positive regulation of defense response GO:0031349 124 0.016
cation transmembrane transport GO:0098655 266 0.016
regulation of rna splicing GO:0043484 37 0.016
viral genome replication GO:0019079 17 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
Yeast
interleukin 6 production GO:0032635 58 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
positive regulation of interferon gamma production GO:0032729 39 0.016
negative regulation of viral process GO:0048525 23 0.016
regulation of neuron death GO:1901214 134 0.016
3 utr mediated mrna stabilization GO:0070935 2 0.016
muscle cell apoptotic process GO:0010657 18 0.016
response to peptide hormone GO:0043434 127 0.016
positive regulation of binding GO:0051099 49 0.016
sleep GO:0030431 7 0.015
positive regulation of rna splicing GO:0033120 12 0.015
striated muscle cell apoptotic process GO:0010658 12 0.015
regulation of binding GO:0051098 111 0.015
immunoglobulin production GO:0002377 73 0.015
regulation of stress activated mapk cascade GO:0032872 69 0.015
fatty acid metabolic process GO:0006631 121 0.015
rhythmic behavior GO:0007622 15 0.015
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.015
regulation of vasculature development GO:1901342 88 0.015
oocyte axis specification GO:0007309 2 0.015
axonogenesis GO:0007409 274 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
protein deubiquitination GO:0016579 19 0.014
protein depolymerization GO:0051261 34 0.014
kidney development GO:0001822 213 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
stress activated mapk cascade GO:0051403 80 0.014
negative regulation of synapse assembly GO:0051964 3 0.014
b cell activation GO:0042113 161 0.014
maintenance of protein localization in organelle GO:0072595 2 0.014
positive regulation of peptidase activity GO:0010952 49 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
negative regulation of protein ubiquitination GO:0031397 19 0.014
glycerophospholipid biosynthetic process GO:0046474 32 0.014
positive regulation of interferon alpha production GO:0032727 4 0.014
chromatin modification GO:0016568 187 0.014
regulation of viral genome replication GO:0045069 13 0.014
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.013
regulation of cell shape GO:0008360 39 0.013
genitalia development GO:0048806 37 0.013
prostaglandin metabolic process GO:0006693 11 0.013
mitochondrion degradation GO:0000422 3 0.013
negative regulation of multi organism process GO:0043901 68 0.013
organelle fission GO:0048285 170 0.013
positive regulation of lamellipodium assembly GO:0010592 2 0.013
cell activation involved in immune response GO:0002263 126 0.013
renal system development GO:0072001 225 0.013
cellular biogenic amine metabolic process GO:0006576 28 0.013
regulation of protein localization to nucleus GO:1900180 60 0.013
positive regulation of angiogenesis GO:0045766 46 0.013
germ cell development GO:0007281 185 0.013
somatic diversification of immunoglobulins GO:0016445 43 0.013
positive regulation of cytokine production GO:0001819 174 0.013
regulation of cellular amine metabolic process GO:0033238 20 0.013
er nucleus signaling pathway GO:0006984 27 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.013
cognition GO:0050890 149 0.013
positive regulation of cell activation GO:0050867 158 0.013
regulation of centrosome cycle GO:0046605 10 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
regulation of cell cycle process GO:0010564 160 0.012
regulation of lamellipodium assembly GO:0010591 3 0.012
innate immune response GO:0045087 157 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
response to misfolded protein GO:0051788 5 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
digestive system development GO:0055123 200 0.012
ribosome localization GO:0033750 1 0.012
response to transforming growth factor beta GO:0071559 88 0.012
regulation of cell motility GO:2000145 236 0.012
positive regulation of cell motility GO:2000147 116 0.012
heart process GO:0003015 94 0.012
calcium ion transmembrane transport GO:0070588 85 0.012
nuclear export GO:0051168 34 0.012
organic acid biosynthetic process GO:0016053 86 0.012
regulation of defense response GO:0031347 233 0.012
centrosome organization GO:0051297 26 0.012
pallium development GO:0021543 120 0.012
cellular response to metal ion GO:0071248 31 0.012
centrosome duplication GO:0051298 16 0.012
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
response to oxidative stress GO:0006979 123 0.011
male genitalia morphogenesis GO:0048808 4 0.011
macrophage activation GO:0042116 27 0.011
mitotic cell cycle process GO:1903047 159 0.011
cation transport GO:0006812 399 0.011
interspecies interaction between organisms GO:0044419 83 0.011
regulation of atp catabolic process GO:1903289 9 0.011
regulation of cytokine production GO:0001817 266 0.011
cell maturation GO:0048469 127 0.011
positive regulation of transferase activity GO:0051347 167 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.011
cytokine production GO:0001816 319 0.011
gene silencing by mirna GO:0035195 10 0.011
cellular response to decreased oxygen levels GO:0036294 18 0.011
cell adhesion GO:0007155 329 0.011
negative regulation of neuron differentiation GO:0045665 101 0.011
regulation of protein export from nucleus GO:0046825 11 0.011
cotranslational protein targeting to membrane GO:0006613 2 0.011
epithelial cell development GO:0002064 159 0.011
response to radiation GO:0009314 165 0.011
chemotaxis GO:0006935 247 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
Yeast
multi multicellular organism process GO:0044706 109 0.011
fatty acid derivative biosynthetic process GO:1901570 15 0.011
blood circulation GO:0008015 195 0.011
neuron migration GO:0001764 122 0.011
cilium morphogenesis GO:0060271 102 0.011
myofibril assembly GO:0030239 34 0.011
spermine metabolic process GO:0008215 3 0.011
regulation of mapk cascade GO:0043408 248 0.011
positive regulation of immune effector process GO:0002699 107 0.011
extracellular structure organization GO:0043062 148 0.011
placenta development GO:0001890 140 0.011
negative regulation of mapk cascade GO:0043409 65 0.011
meiotic nuclear division GO:0007126 115 0.011
regulation of ion homeostasis GO:2000021 64 0.011
nucleotide metabolic process GO:0009117 332 0.011
Yeast
unsaturated fatty acid metabolic process GO:0033559 31 0.011
carbohydrate homeostasis GO:0033500 128 0.010
cellular response to inorganic substance GO:0071241 37 0.010
organelle localization GO:0051640 179 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.010
response to light stimulus GO:0009416 135 0.010
regulation of multi organism process GO:0043900 111 0.010
cerebellum development GO:0021549 77 0.010
compound eye development GO:0048749 1 0.010
response to estrogen GO:0043627 24 0.010
icosanoid biosynthetic process GO:0046456 15 0.010
response to extracellular stimulus GO:0009991 127 0.010
microtubule severing GO:0051013 5 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
positive regulation of atp catabolic process GO:1903291 3 0.010
axonal fasciculation GO:0007413 15 0.010

Hsph1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.068
nervous system disease DOID:863 0 0.068
paraplegia DOID:607 0 0.023
hereditary spastic paraplegia DOID:2476 0 0.023
central nervous system disease DOID:331 0 0.023
immune system disease DOID:2914 0 0.018
physical disorder DOID:0080015 0 0.013
congenital nervous system abnormality DOID:2490 0 0.013
primary immunodeficiency disease DOID:612 0 0.010