Mus musculus

518 known processes

Nod2

nucleotide-binding oligomerization domain containing 2

(Aliases: BLAU,Card15,CD,IBD1,F830032C23Rik,ACUG,Nlrc2)

Nod2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytokine production GO:0001816 319 0.469
regulation of cellular amino acid metabolic process GO:0006521 5 0.278
regulation of cellular ketone metabolic process GO:0010565 66 0.261
skeletal system development GO:0001501 356 0.261
amine metabolic process GO:0009308 45 0.237
mapk cascade GO:0000165 281 0.237
cellular amino acid metabolic process GO:0006520 103 0.230
positive regulation of cellular amine metabolic process GO:0033240 5 0.210
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.204
apoptotic signaling pathway GO:0097190 306 0.203
immune effector process GO:0002252 321 0.201
regulation of apoptotic signaling pathway GO:2001233 197 0.189
regulation of protein kinase activity GO:0045859 232 0.185
cellular response to dna damage stimulus GO:0006974 207 0.178
dna metabolic process GO:0006259 303 0.176
regulation of homeostatic process GO:0032844 182 0.172
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.169
adaptive immune response GO:0002250 155 0.168
positive regulation of cell activation GO:0050867 158 0.168
positive regulation of protein modification process GO:0031401 299 0.167
regulation of t cell activation GO:0050863 170 0.164
leukocyte differentiation GO:0002521 342 0.158
stem cell differentiation GO:0048863 268 0.155
cellular amine metabolic process GO:0044106 44 0.155
negative regulation of immune system process GO:0002683 209 0.151
regulation of kinase activity GO:0043549 249 0.151
regulation of cytokine production GO:0001817 266 0.150
positive regulation of kinase activity GO:0033674 155 0.150
peptidyl amino acid modification GO:0018193 336 0.147
cellular ketone metabolic process GO:0042180 84 0.145
response to radiation GO:0009314 165 0.142
regulation of cell motility GO:2000145 236 0.141
positive regulation of nervous system development GO:0051962 221 0.137
regulation of neuron differentiation GO:0045664 281 0.136
kidney development GO:0001822 213 0.135
regulation of cellular amine metabolic process GO:0033238 20 0.135
gland development GO:0048732 330 0.134
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.130
placenta development GO:0001890 140 0.127
positive regulation of cytokine production GO:0001819 174 0.123
positive regulation of cell development GO:0010720 237 0.122
leukocyte activation involved in immune response GO:0002366 126 0.119
ras protein signal transduction GO:0007265 77 0.117
cell type specific apoptotic process GO:0097285 268 0.114
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.113
immune response activating signal transduction GO:0002757 116 0.111
positive regulation of apoptotic signaling pathway GO:2001235 95 0.111
renal system development GO:0072001 225 0.108
cation transport GO:0006812 399 0.108
heart morphogenesis GO:0003007 178 0.108
regulation of cell activation GO:0050865 289 0.108
reactive oxygen species metabolic process GO:0072593 84 0.107
response to amino acid GO:0043200 37 0.106
fat cell differentiation GO:0045444 160 0.104
ion transmembrane transport GO:0034220 361 0.104
protein secretion GO:0009306 111 0.104
myeloid cell differentiation GO:0030099 233 0.103
cytokine mediated signaling pathway GO:0019221 115 0.101
peptidyl tyrosine modification GO:0018212 145 0.101
urogenital system development GO:0001655 261 0.099
regulation of response to wounding GO:1903034 189 0.099
forebrain development GO:0030900 302 0.098
positive regulation of protein phosphorylation GO:0001934 242 0.097
intrinsic apoptotic signaling pathway GO:0097193 132 0.096
negative regulation of phosphate metabolic process GO:0045936 184 0.095
Mouse
cytokine secretion GO:0050663 72 0.095
morphogenesis of a branching structure GO:0001763 203 0.095
regulation of cellular response to stress GO:0080135 159 0.095
t cell activation GO:0042110 289 0.093
negative regulation of cellular protein metabolic process GO:0032269 247 0.092
regulation of leukocyte mediated immunity GO:0002703 104 0.092
negative regulation of apoptotic signaling pathway GO:2001234 104 0.091
regulation of protein secretion GO:0050708 82 0.091
striated muscle tissue development GO:0014706 293 0.090
morphogenesis of a branching epithelium GO:0061138 193 0.090
renal tubule development GO:0061326 87 0.089
regulation of lymphocyte activation GO:0051249 240 0.089
negative regulation of cell activation GO:0050866 111 0.089
extrinsic apoptotic signaling pathway GO:0097191 126 0.088
response to molecule of bacterial origin GO:0002237 143 0.088
regulation of adaptive immune response GO:0002819 90 0.088
cellular homeostasis GO:0019725 240 0.086
cellular chemical homeostasis GO:0055082 215 0.086
response to acid chemical GO:0001101 111 0.085
sensory organ morphogenesis GO:0090596 242 0.085
embryonic placenta development GO:0001892 98 0.085
response to organonitrogen compound GO:0010243 246 0.085
blood vessel morphogenesis GO:0048514 285 0.084
peptidyl tyrosine phosphorylation GO:0018108 143 0.084
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.084
cellular response to lipid GO:0071396 145 0.083
g protein coupled receptor signaling pathway GO:0007186 243 0.082
regulation of membrane potential GO:0042391 192 0.082
branching morphogenesis of an epithelial tube GO:0048754 159 0.082
protein processing GO:0016485 163 0.082
Mouse
regulation of cellular catabolic process GO:0031329 242 0.082
Mouse
positive regulation of cell adhesion GO:0045785 80 0.082
neuron death GO:0070997 154 0.081
muscle system process GO:0003012 141 0.081
transmission of nerve impulse GO:0019226 76 0.080
regulation of defense response GO:0031347 233 0.079
negative regulation of neuron apoptotic process GO:0043524 92 0.079
lymphocyte differentiation GO:0030098 242 0.079
regulation of transferase activity GO:0051338 263 0.078
cellular response to growth factor stimulus GO:0071363 197 0.078
metal ion homeostasis GO:0055065 189 0.078
regulation of cell projection organization GO:0031344 206 0.077
regulation of cell migration GO:0030334 219 0.076
epithelial tube morphogenesis GO:0060562 303 0.076
epithelial cell proliferation GO:0050673 174 0.076
single organism cell adhesion GO:0098602 156 0.076
inflammatory response GO:0006954 244 0.075
spermatogenesis GO:0007283 284 0.075
b cell activation GO:0042113 161 0.075
response to organic cyclic compound GO:0014070 198 0.075
positive regulation of t cell activation GO:0050870 101 0.074
regulation of establishment of protein localization GO:0070201 181 0.074
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.074
regulation of leukocyte differentiation GO:1902105 159 0.074
stem cell development GO:0048864 219 0.073
regulation of peptidase activity GO:0052547 96 0.073
Mouse
positive regulation of cell death GO:0010942 224 0.073
Mouse
camera type eye development GO:0043010 266 0.073
regulation of protein localization GO:0032880 231 0.072
regulation of neuron apoptotic process GO:0043523 122 0.071
cation transmembrane transport GO:0098655 266 0.071
t cell differentiation GO:0030217 174 0.071
positive regulation of programmed cell death GO:0043068 218 0.070
Mouse
cation homeostasis GO:0055080 212 0.069
transmembrane transport GO:0055085 412 0.069
protein maturation GO:0051604 176 0.069
Mouse
negative regulation of cell proliferation GO:0008285 296 0.069
regulation of inflammatory response GO:0050727 147 0.068
mesonephros development GO:0001823 97 0.068
cytokine metabolic process GO:0042107 71 0.068
cytokine biosynthetic process GO:0042089 68 0.067
coagulation GO:0050817 78 0.067
muscle tissue development GO:0060537 308 0.067
regulation of myeloid cell differentiation GO:0045637 96 0.066
cellular response to cytokine stimulus GO:0071345 189 0.066
Mouse
muscle contraction GO:0006936 101 0.066
nephron development GO:0072006 109 0.065
neuron apoptotic process GO:0051402 142 0.065
oxidation reduction process GO:0055114 342 0.065
regulation of cytokine secretion GO:0050707 61 0.064
nucleoside phosphate metabolic process GO:0006753 338 0.064
calcium ion transport GO:0006816 159 0.064
skeletal system morphogenesis GO:0048705 203 0.063
regulation of cell adhesion GO:0030155 154 0.063
small gtpase mediated signal transduction GO:0007264 97 0.063
multicellular organismal signaling GO:0035637 91 0.063
negative regulation of lymphocyte activation GO:0051250 91 0.062
wound healing GO:0042060 157 0.062
Mouse
regulation of t cell proliferation GO:0042129 92 0.062
circulatory system process GO:0003013 197 0.062
negative regulation of phosphorylation GO:0042326 166 0.062
Mouse
lymphocyte activation involved in immune response GO:0002285 93 0.061
protein ubiquitination GO:0016567 171 0.061
myeloid leukocyte activation GO:0002274 83 0.061
wnt signaling pathway GO:0016055 188 0.060
protein modification by small protein conjugation GO:0032446 187 0.060
regulation of ion transport GO:0043269 215 0.060
sensory perception GO:0007600 245 0.059
ribonucleotide metabolic process GO:0009259 291 0.059
activation of immune response GO:0002253 138 0.059
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.058
cellular response to oxidative stress GO:0034599 76 0.058
homeostasis of number of cells GO:0048872 210 0.058
regulation of mapk cascade GO:0043408 248 0.057
cellular divalent inorganic cation homeostasis GO:0072503 127 0.057
purine containing compound metabolic process GO:0072521 311 0.057
epidermis development GO:0008544 187 0.057
regulation of engulfment of apoptotic cell GO:1901074 2 0.057
positive regulation of mapk cascade GO:0043410 170 0.056
divalent metal ion transport GO:0070838 172 0.056
negative regulation of t cell activation GO:0050868 65 0.056
divalent inorganic cation homeostasis GO:0072507 138 0.056
macromolecule catabolic process GO:0009057 281 0.056
regulation of leukocyte proliferation GO:0070663 121 0.056
calcium ion homeostasis GO:0055074 127 0.055
lymphocyte mediated immunity GO:0002449 139 0.055
cellular metal ion homeostasis GO:0006875 151 0.055
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.055
muscle cell differentiation GO:0042692 261 0.055
rho protein signal transduction GO:0007266 32 0.055
myeloid leukocyte differentiation GO:0002573 119 0.055
response to oxidative stress GO:0006979 123 0.054
kidney epithelium development GO:0072073 121 0.054
negative regulation of defense response GO:0031348 77 0.054
regulation of erk1 and erk2 cascade GO:0070372 71 0.053
actin filament organization GO:0007015 113 0.053
carbohydrate homeostasis GO:0033500 128 0.053
male gamete generation GO:0048232 285 0.052
appendage development GO:0048736 166 0.052
carbohydrate derivative catabolic process GO:1901136 231 0.052
positive regulation of protein kinase activity GO:0045860 144 0.052
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.052
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.052
cellular response to organonitrogen compound GO:0071417 145 0.052
glial cell differentiation GO:0010001 131 0.052
nephron tubule development GO:0072080 84 0.052
regulation of protein transport GO:0051223 163 0.052
immune response regulating signaling pathway GO:0002764 125 0.051
regulation of protein processing GO:0070613 96 0.051
cellular ion homeostasis GO:0006873 165 0.051
lymphocyte homeostasis GO:0002260 64 0.051
t cell activation involved in immune response GO:0002286 43 0.050
negative regulation of protein maturation GO:1903318 79 0.050
negative regulation of molecular function GO:0044092 258 0.050
multicellular organism growth GO:0035264 161 0.050
response to extracellular stimulus GO:0009991 127 0.050
negative regulation of cellular amine metabolic process GO:0033239 1 0.050
positive regulation of vasoconstriction GO:0045907 4 0.050
regulation of interferon gamma production GO:0032649 57 0.050
telencephalon development GO:0021537 186 0.049
negative regulation of endopeptidase activity GO:0010951 44 0.048
negative regulation of proteolysis GO:0045861 74 0.048
axonogenesis GO:0007409 274 0.048
nephron epithelium morphogenesis GO:0072088 68 0.048
hematopoietic progenitor cell differentiation GO:0002244 143 0.048
phagocytosis GO:0006909 66 0.047
carbohydrate metabolic process GO:0005975 230 0.047
regulation of neuron death GO:1901214 134 0.047
response to oxygen levels GO:0070482 62 0.047
regulation of system process GO:0044057 200 0.047
regulation of protein serine threonine kinase activity GO:0071900 157 0.047
erk1 and erk2 cascade GO:0070371 77 0.046
nucleobase containing small molecule metabolic process GO:0055086 352 0.046
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.046
cell adhesion GO:0007155 329 0.046
negative regulation of cytokine production GO:0001818 84 0.046
leukocyte proliferation GO:0070661 172 0.045
negative regulation of immune effector process GO:0002698 55 0.045
positive regulation of t cell differentiation GO:0045582 52 0.045
regulation of ion transmembrane transport GO:0034765 119 0.045
heterocycle catabolic process GO:0046700 280 0.045
cellular calcium ion homeostasis GO:0006874 119 0.045
inorganic ion transmembrane transport GO:0098660 234 0.045
regulation of metal ion transport GO:0010959 106 0.045
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.044
Mouse
neural tube development GO:0021915 160 0.044
negative regulation of homeostatic process GO:0032845 71 0.044
mesonephric tubule morphogenesis GO:0072171 63 0.044
labyrinthine layer development GO:0060711 49 0.044
neuronal action potential GO:0019228 54 0.044
angiogenesis GO:0001525 201 0.044
positive regulation of cellular catabolic process GO:0031331 148 0.044
action potential GO:0001508 78 0.044
regulation of secretion GO:0051046 274 0.043
organonitrogen compound biosynthetic process GO:1901566 192 0.043
negative regulation of intracellular signal transduction GO:1902532 167 0.043
Mouse
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.043
connective tissue development GO:0061448 179 0.042
renal tubule morphogenesis GO:0061333 72 0.042
extracellular matrix organization GO:0030198 147 0.042
germ cell development GO:0007281 185 0.042
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.042
regulation of cysteine type endopeptidase activity GO:2000116 65 0.042
Mouse
inorganic cation transmembrane transport GO:0098662 207 0.042
pallium development GO:0021543 120 0.041
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.041
nucleotide metabolic process GO:0009117 332 0.041
neuron migration GO:0001764 122 0.041
positive regulation of ion transport GO:0043270 65 0.041
regulation of cell cycle GO:0051726 281 0.041
antigen receptor mediated signaling pathway GO:0050851 64 0.041
negative regulation of peptidase activity GO:0010466 46 0.040
purine nucleoside triphosphate catabolic process GO:0009146 203 0.040
regulation of myeloid leukocyte differentiation GO:0002761 58 0.040
sequestering of metal ion GO:0051238 19 0.040
ribose phosphate metabolic process GO:0019693 291 0.040
positive regulation of organelle organization GO:0010638 128 0.040
response to growth factor GO:0070848 198 0.040
kidney morphogenesis GO:0060993 83 0.040
somatic diversification of immune receptors GO:0002200 53 0.040
response to nutrient levels GO:0031667 109 0.040
cellular response to molecule of bacterial origin GO:0071219 83 0.040
regulation of ras protein signal transduction GO:0046578 114 0.040
negative regulation of neuron death GO:1901215 98 0.039
positive regulation of transferase activity GO:0051347 167 0.039
divalent inorganic cation transport GO:0072511 178 0.039
negative regulation of secretion GO:0051048 61 0.039
cellular response to external stimulus GO:0071496 88 0.039
reactive nitrogen species metabolic process GO:2001057 0 0.039
t cell differentiation in thymus GO:0033077 77 0.039
mitochondrion organization GO:0007005 134 0.038
negative regulation of protein metabolic process GO:0051248 282 0.038
anion transport GO:0006820 177 0.038
dna repair GO:0006281 107 0.038
defense response to other organism GO:0098542 197 0.038
regulation of transmembrane transport GO:0034762 128 0.037
regulation of interleukin 10 secretion GO:2001179 4 0.037
regulation of ossification GO:0030278 112 0.037
notch signaling pathway GO:0007219 71 0.037
mucopolysaccharide metabolic process GO:1903510 25 0.037
jak stat cascade GO:0007259 42 0.037
limb development GO:0060173 166 0.037
microtubule based process GO:0007017 236 0.037
positive regulation of hydrolase activity GO:0051345 148 0.037
Mouse
dna recombination GO:0006310 92 0.037
peptide transport GO:0015833 133 0.037
positive regulation of cell migration GO:0030335 109 0.036
aminoglycan metabolic process GO:0006022 34 0.036
regulation of anatomical structure size GO:0090066 178 0.036
engulfment of apoptotic cell GO:0043652 3 0.036
positive regulation of inflammatory response GO:0050729 47 0.036
interleukin 10 secretion GO:0072608 4 0.036
ureteric bud morphogenesis GO:0060675 62 0.036
protein catabolic process GO:0030163 221 0.036
protein kinase b signaling GO:0043491 74 0.036
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.035
cellular response to amino acid stimulus GO:0071230 29 0.035
protein modification by small protein conjugation or removal GO:0070647 207 0.035
regulation of cellular component biogenesis GO:0044087 181 0.035
regulation of secretion by cell GO:1903530 249 0.035
positive regulation of lymphocyte differentiation GO:0045621 61 0.035
positive regulation of adaptive immune response GO:0002821 61 0.035
negative regulation of growth GO:0045926 99 0.035
interferon gamma production GO:0032609 67 0.035
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.035
single organismal cell cell adhesion GO:0016337 131 0.035
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.035
glucose homeostasis GO:0042593 128 0.034
negative regulation of hydrolase activity GO:0051346 71 0.034
regulation of endopeptidase activity GO:0052548 89 0.034
Mouse
odontogenesis GO:0042476 78 0.034
small molecule biosynthetic process GO:0044283 132 0.034
lateral inhibition GO:0046331 1 0.033
amide transport GO:0042886 138 0.033
positive regulation of homeostatic process GO:0032846 64 0.033
leukocyte homeostasis GO:0001776 79 0.033
cytoplasmic transport GO:0016482 234 0.033
respiratory system development GO:0060541 190 0.033
leukocyte mediated immunity GO:0002443 174 0.033
regulation of production of molecular mediator of immune response GO:0002700 65 0.033
regulation of organelle organization GO:0033043 289 0.033
b cell homeostasis GO:0001782 34 0.033
bone development GO:0060348 120 0.033
regulation of neuron projection development GO:0010975 169 0.033
neuron projection guidance GO:0097485 141 0.033
forebrain cell migration GO:0021885 58 0.033
negative regulation of protein processing GO:0010955 79 0.032
negative regulation of phosphorus metabolic process GO:0010563 184 0.032
Mouse
immunoglobulin production GO:0002377 73 0.032
regulation of action potential GO:0098900 4 0.032
mitotic cell cycle GO:0000278 195 0.032
positive regulation of myeloid cell differentiation GO:0045639 43 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
cellular lipid metabolic process GO:0044255 323 0.032
regulation of lymphocyte mediated immunity GO:0002706 84 0.032
negative regulation of cellular component organization GO:0051129 194 0.032
peptidyl serine phosphorylation GO:0018105 74 0.031
negative regulation of inflammatory response GO:0050728 61 0.031
mesonephric tubule development GO:0072164 94 0.031
regulation of map kinase activity GO:0043405 120 0.031
mesonephric epithelium development GO:0072163 94 0.030
retina development in camera type eye GO:0060041 119 0.030
regulation of proteolysis GO:0030162 164 0.030
Mouse
regulation of interleukin 6 production GO:0032675 55 0.030
hematopoietic stem cell migration GO:0035701 1 0.030
blood coagulation GO:0007596 76 0.030
inflammatory response to wounding GO:0090594 4 0.030
positive regulation of secretion GO:0051047 130 0.030
response to inorganic substance GO:0010035 96 0.030
regulation of cytokine biosynthetic process GO:0042035 59 0.030
positive regulation of defense response GO:0031349 124 0.029
embryonic appendage morphogenesis GO:0035113 126 0.029
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.029
positive regulation of map kinase activity GO:0043406 84 0.029
regulation of systemic arterial blood pressure GO:0003073 61 0.029
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.029
digestive tract development GO:0048565 190 0.029
regulation of rho protein signal transduction GO:0035023 71 0.029
digestive system development GO:0055123 200 0.029
embryonic organ morphogenesis GO:0048562 276 0.029
cellular response to organic cyclic compound GO:0071407 87 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
purine containing compound catabolic process GO:0072523 213 0.029
methylation GO:0032259 134 0.028
wound healing involved in inflammatory response GO:0002246 4 0.028
chromatin organization GO:0006325 206 0.028
interleukin 2 production GO:0032623 33 0.028
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.028
membrane organization GO:0061024 245 0.028
nephron morphogenesis GO:0072028 69 0.028
odontogenesis of dentin containing tooth GO:0042475 66 0.028
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.028
regulation of b cell apoptotic process GO:0002902 13 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.028
circadian rhythm GO:0007623 114 0.028
maintenance of location GO:0051235 89 0.028
regulation of hormone levels GO:0010817 211 0.028
positive regulation of protein secretion GO:0050714 52 0.028
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.028
t cell extravasation GO:0072683 4 0.028
positive regulation of nucleotide metabolic process GO:0045981 114 0.028
positive regulation of epithelial cell proliferation GO:0050679 68 0.028
monocarboxylic acid metabolic process GO:0032787 191 0.027
ureteric bud development GO:0001657 94 0.027
cellular amide metabolic process GO:0043603 58 0.027
anatomical structure homeostasis GO:0060249 145 0.027
immunoglobulin mediated immune response GO:0016064 69 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
ribonucleotide catabolic process GO:0009261 208 0.027
purine ribonucleotide catabolic process GO:0009154 208 0.027
alpha beta t cell activation GO:0046631 91 0.027
cellular response to extracellular stimulus GO:0031668 81 0.027
positive regulation of lymphocyte activation GO:0051251 140 0.027
respiratory tube development GO:0030323 167 0.027
regulation of alpha beta t cell activation GO:0046634 53 0.027
regulation of fat cell differentiation GO:0045598 81 0.027
positive regulation of t cell proliferation GO:0042102 52 0.027
myotube differentiation GO:0014902 105 0.027
nuclear transport GO:0051169 139 0.027
synaptic transmission GO:0007268 329 0.027
microglia differentiation GO:0014004 2 0.027
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.027
tissue homeostasis GO:0001894 115 0.027
cell chemotaxis GO:0060326 81 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.027
ossification GO:0001503 216 0.027
exocytosis GO:0006887 121 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
negative regulation of neuron differentiation GO:0045665 101 0.027
negative regulation of leukocyte differentiation GO:1902106 51 0.026
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.026
t cell receptor signaling pathway GO:0050852 46 0.026
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.026
t cell proliferation GO:0042098 120 0.026
bmp signaling pathway GO:0030509 93 0.026
cell activation involved in immune response GO:0002263 126 0.026
response to peptide GO:1901652 136 0.026
morphogenesis of embryonic epithelium GO:0016331 159 0.026
organic anion transport GO:0015711 137 0.026
mesenchyme development GO:0060485 152 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
regulation of body fluid levels GO:0050878 162 0.025
Mouse
modification dependent protein catabolic process GO:0019941 133 0.025
determination of left right symmetry GO:0007368 80 0.025
ear development GO:0043583 200 0.025
nucleoside metabolic process GO:0009116 246 0.025
hormone secretion GO:0046879 128 0.025
female gamete generation GO:0007292 74 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
glycoprotein metabolic process GO:0009100 116 0.025
response to metal ion GO:0010038 47 0.025
response to heat GO:0009408 27 0.025
meiotic cell cycle GO:0051321 122 0.025
nitrogen compound transport GO:0071705 271 0.024
t cell selection GO:0045058 34 0.024
embryonic epithelial tube formation GO:0001838 130 0.024
chromatin modification GO:0016568 187 0.024
regulation of nucleoside metabolic process GO:0009118 130 0.024
embryonic limb morphogenesis GO:0030326 126 0.024
sequestering of calcium ion GO:0051208 18 0.024
positive regulation of neuron differentiation GO:0045666 141 0.024
positive regulation of acute inflammatory response GO:0002675 16 0.024
negative regulation of protein modification process GO:0031400 163 0.024
regulation of protein maturation GO:1903317 96 0.024
nephron tubule morphogenesis GO:0072078 68 0.024
regulation of purine nucleotide metabolic process GO:1900542 169 0.024
positive regulation of leukocyte differentiation GO:1902107 86 0.024
myeloid leukocyte migration GO:0097529 57 0.024
lymphocyte apoptotic process GO:0070227 54 0.024
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.024
negative regulation of cell cycle GO:0045786 123 0.024
positive regulation of proteolysis GO:0045862 85 0.024
Mouse
positive regulation of peptidase activity GO:0010952 49 0.024
Mouse
regulation of organ morphogenesis GO:2000027 144 0.024
leukocyte chemotaxis GO:0030595 69 0.024
regulation of tumor necrosis factor production GO:0032680 49 0.023
negative regulation of cell development GO:0010721 169 0.023
cellular response to peptide GO:1901653 92 0.023
endocytosis GO:0006897 168 0.023
granulocyte chemotaxis GO:0071621 39 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.023
response to ionizing radiation GO:0010212 42 0.023
response to insulin GO:0032868 100 0.023
regulation of hydrolase activity GO:0051336 246 0.023
Mouse
cardiac muscle cell differentiation GO:0055007 69 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
response to peptide hormone GO:0043434 127 0.023
somatic diversification of immunoglobulins GO:0016445 43 0.023
lung development GO:0030324 164 0.023
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.023
regulation of monocyte extravasation GO:2000437 2 0.023
neural tube formation GO:0001841 108 0.023
cerebral cortex development GO:0021987 86 0.023
regulation of blood vessel size GO:0050880 56 0.023

Nod2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.079
nervous system disease DOID:863 0 0.079
central nervous system disease DOID:331 0 0.036
cancer DOID:162 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
neurodegenerative disease DOID:1289 0 0.028
musculoskeletal system disease DOID:17 0 0.027