Mus musculus

0 known processes

Tnpo2

transportin 2 (importin 3, karyopherin beta 2b)

(Aliases: MGC6380,Knpb2b,AI852433,AI464345,Kpnb2b,1110034O24Rik,AA414969,TRN2,IPO3)

Tnpo2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.257
modification dependent protein catabolic process GO:0019941 133 0.232
protein modification by small protein conjugation GO:0032446 187 0.148
protein modification by small protein conjugation or removal GO:0070647 207 0.145
male gamete generation GO:0048232 285 0.133
regulation of cellular ketone metabolic process GO:0010565 66 0.097
homeostasis of number of cells GO:0048872 210 0.095
spermatogenesis GO:0007283 284 0.087
protein catabolic process GO:0030163 221 0.078
ubiquitin dependent protein catabolic process GO:0006511 129 0.068
protein ubiquitination GO:0016567 171 0.065
cellular ketone metabolic process GO:0042180 84 0.064
gtp catabolic process GO:0006184 143 0.062
positive regulation of cellular catabolic process GO:0031331 148 0.060
proteasomal protein catabolic process GO:0010498 98 0.058
cellular protein catabolic process GO:0044257 155 0.058
regulation of cellular amine metabolic process GO:0033238 20 0.056
ion transmembrane transport GO:0034220 361 0.056
membrane organization GO:0061024 245 0.054
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.054
mrna metabolic process GO:0016071 84 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
regulation of organelle organization GO:0033043 289 0.049
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.048
regulation of cellular catabolic process GO:0031329 242 0.048
cellular amine metabolic process GO:0044106 44 0.047
dna metabolic process GO:0006259 303 0.046
regulation of cellular component biogenesis GO:0044087 181 0.046
regulation of cell cycle GO:0051726 281 0.045
cellular response to dna damage stimulus GO:0006974 207 0.045
macromolecule catabolic process GO:0009057 281 0.045
amine metabolic process GO:0009308 45 0.045
cellular lipid metabolic process GO:0044255 323 0.044
axonogenesis GO:0007409 274 0.044
cellular nitrogen compound catabolic process GO:0044270 280 0.044
transmembrane transport GO:0055085 412 0.043
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
cellular macromolecule catabolic process GO:0044265 206 0.041
organophosphate catabolic process GO:0046434 232 0.041
microtubule cytoskeleton organization GO:0000226 157 0.040
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.040
cation transport GO:0006812 399 0.039
multicellular organism growth GO:0035264 161 0.039
positive regulation of protein modification process GO:0031401 299 0.038
cellular amino acid metabolic process GO:0006520 103 0.037
modification dependent macromolecule catabolic process GO:0043632 133 0.037
positive regulation of protein phosphorylation GO:0001934 242 0.036
negative regulation of cellular component organization GO:0051129 194 0.036
mitotic cell cycle process GO:1903047 159 0.035
negative regulation of synapse assembly GO:0051964 3 0.035
aromatic compound catabolic process GO:0019439 286 0.034
gtp metabolic process GO:0046039 144 0.034
cation transmembrane transport GO:0098655 266 0.033
guanosine containing compound catabolic process GO:1901069 144 0.033
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.033
mitotic cell cycle GO:0000278 195 0.033
positive regulation of dna templated transcription elongation GO:0032786 2 0.033
regulation of cellular protein catabolic process GO:1903362 61 0.032
nitrogen compound transport GO:0071705 271 0.031
regulation of cytoskeleton organization GO:0051493 122 0.031
retrograde transport endosome to golgi GO:0042147 2 0.030
guanosine containing compound metabolic process GO:1901068 144 0.030
cell growth GO:0016049 130 0.030
rna processing GO:0006396 105 0.030
habituation GO:0046959 3 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
purine nucleotide metabolic process GO:0006163 302 0.028
regulation of protein localization GO:0032880 231 0.028
Fly
heterocycle catabolic process GO:0046700 280 0.028
carbohydrate metabolic process GO:0005975 230 0.028
oocyte construction GO:0007308 2 0.028
histone modification GO:0016570 159 0.028
apoptotic signaling pathway GO:0097190 306 0.027
engulfment of apoptotic cell GO:0043652 3 0.027
regulation of proteolysis GO:0030162 164 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
organic cyclic compound catabolic process GO:1901361 295 0.027
regulation of gtp catabolic process GO:0033124 113 0.026
oocyte axis specification GO:0007309 2 0.026
regulation of nucleoside metabolic process GO:0009118 130 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
regulation of hydrolase activity GO:0051336 246 0.025
immune effector process GO:0002252 321 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
purine ribonucleoside catabolic process GO:0046130 205 0.025
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.024
leukocyte differentiation GO:0002521 342 0.024
establishment of organelle localization GO:0051656 122 0.024
innate immune response GO:0045087 157 0.024
skeletal system development GO:0001501 356 0.024
chemotaxis GO:0006935 247 0.024
myeloid cell differentiation GO:0030099 233 0.023
germ cell development GO:0007281 185 0.023
compound eye development GO:0048749 1 0.023
maintenance of location GO:0051235 89 0.023
circadian rhythm GO:0007623 114 0.023
multicellular organismal signaling GO:0035637 91 0.023
regulation of protein catabolic process GO:0042176 108 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
ribonucleoside catabolic process GO:0042454 206 0.023
regulation of lymphocyte activation GO:0051249 240 0.022
dephosphorylation GO:0016311 129 0.022
peptidyl amino acid modification GO:0018193 336 0.022
positive regulation of organelle organization GO:0010638 128 0.022
regulation of anatomical structure size GO:0090066 178 0.021
methylation GO:0032259 134 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
negative regulation of growth GO:0045926 99 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
oxidation reduction process GO:0055114 342 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
negative regulation of molecular function GO:0044092 258 0.021
regulation of vesicle mediated transport GO:0060627 139 0.021
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.021
regulation of membrane potential GO:0042391 192 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
organelle localization GO:0051640 179 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
nucleotide catabolic process GO:0009166 217 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.020
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
cytoplasmic transport GO:0016482 234 0.020
Fly
positive regulation of nervous system development GO:0051962 221 0.020
dna alkylation GO:0006305 43 0.020
cell type specific apoptotic process GO:0097285 268 0.020
cell adhesion GO:0007155 329 0.019
rna splicing GO:0008380 54 0.019
cellularization GO:0007349 1 0.019
purine containing compound metabolic process GO:0072521 311 0.019
macromolecule methylation GO:0043414 120 0.019
glycerolipid metabolic process GO:0046486 122 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
mapk cascade GO:0000165 281 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
glycerophospholipid metabolic process GO:0006650 71 0.019
regulation of cellular component size GO:0032535 121 0.019
tissue homeostasis GO:0001894 115 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
cellular homeostasis GO:0019725 240 0.019
protein methylation GO:0006479 81 0.018
negative regulation of nervous system development GO:0051961 156 0.018
protein processing GO:0016485 163 0.018
telencephalon development GO:0021537 186 0.018
microtubule based process GO:0007017 236 0.018
actin cytoskeleton organization GO:0030036 220 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
organic anion transport GO:0015711 137 0.018
regulation of cell projection organization GO:0031344 206 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
regulation of protein complex assembly GO:0043254 83 0.018
stem cell differentiation GO:0048863 268 0.018
regulation of homeostatic process GO:0032844 182 0.018
rac protein signal transduction GO:0016601 13 0.018
regulation of secretion GO:0051046 274 0.018
regulation of nucleotide catabolic process GO:0030811 122 0.018
intracellular protein transport GO:0006886 204 0.018
Fly
fertilization GO:0009566 127 0.018
dna modification GO:0006304 50 0.018
positive regulation of growth GO:0045927 104 0.018
regulation of cell cycle process GO:0010564 160 0.018
regulation of mitotic cell cycle phase transition GO:1901990 73 0.017
histone methylation GO:0016571 71 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
positive regulation of neuron differentiation GO:0045666 141 0.017
protein polyubiquitination GO:0000209 33 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
positive regulation of nucleotide catabolic process GO:0030813 88 0.017
anion transport GO:0006820 177 0.017
endomembrane system organization GO:0010256 147 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
positive regulation of gtpase activity GO:0043547 85 0.017
lymphocyte differentiation GO:0030098 242 0.017
protein oligomerization GO:0051259 67 0.017
meiotic cell cycle GO:0051321 122 0.016
response to organonitrogen compound GO:0010243 246 0.016
organelle assembly GO:0070925 177 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
rhythmic process GO:0048511 174 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
positive regulation of protein catabolic process GO:0045732 60 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
regulation of ras gtpase activity GO:0032318 88 0.016
regulation of cell size GO:0008361 72 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
organelle fission GO:0048285 170 0.016
neuron projection guidance GO:0097485 141 0.016
purine containing compound catabolic process GO:0072523 213 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
regionalization GO:0003002 337 0.016
rab protein signal transduction GO:0032482 1 0.016
mitochondrion organization GO:0007005 134 0.016
regulation of neuron differentiation GO:0045664 281 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
negative regulation of proteolysis GO:0045861 74 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
glycerolipid biosynthetic process GO:0045017 50 0.015
synaptic transmission GO:0007268 329 0.015
nuclear division GO:0000280 158 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
spermatid development GO:0007286 108 0.015
regulation of proteasomal protein catabolic process GO:0061136 46 0.015
response to insulin GO:0032868 100 0.015
nucleoside catabolic process GO:0009164 206 0.015
maternal determination of anterior posterior axis embryo GO:0008358 2 0.015
meiosis i GO:0007127 60 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.015
cell fate commitment GO:0045165 210 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
neuronal action potential GO:0019228 54 0.015
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
bone development GO:0060348 120 0.015
covalent chromatin modification GO:0016569 163 0.015
skin development GO:0043588 220 0.015
histone h4 k16 acetylation GO:0043984 3 0.015
ras protein signal transduction GO:0007265 77 0.015
myeloid cell homeostasis GO:0002262 114 0.014
histone h3 k9 methylation GO:0051567 17 0.014
regulation of chromosome organization GO:0033044 83 0.014
regulation of secretion by cell GO:1903530 249 0.014
exocytosis GO:0006887 121 0.014
lipid modification GO:0030258 65 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
regulation of neuron projection development GO:0010975 169 0.014
alcohol metabolic process GO:0006066 116 0.014
protein localization to organelle GO:0033365 185 0.014
Fly
chromatin organization GO:0006325 206 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
rho protein signal transduction GO:0007266 32 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
Fly
carbohydrate homeostasis GO:0033500 128 0.014
single organism cell adhesion GO:0098602 156 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
blood circulation GO:0008015 195 0.014
spermatid differentiation GO:0048515 115 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
heterochromatin assembly GO:0031507 2 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.014
sensory perception GO:0007600 245 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
establishment or maintenance of cell polarity GO:0007163 86 0.014
regulation of hormone levels GO:0010817 211 0.013
muscle tissue development GO:0060537 308 0.013
cognition GO:0050890 149 0.013
gland development GO:0048732 330 0.013
l amino acid transport GO:0015807 32 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
negative regulation of cell cycle GO:0045786 123 0.013
regulation of system process GO:0044057 200 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
nucleotide metabolic process GO:0009117 332 0.013
regulation of kinase activity GO:0043549 249 0.013
regulation of ion transport GO:0043269 215 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
negative regulation of organelle organization GO:0010639 90 0.013
actin filament organization GO:0007015 113 0.013
dendrite development GO:0016358 115 0.013
photoreceptor cell morphogenesis GO:0008594 3 0.013
dna methylation GO:0006306 43 0.013
lipoprotein metabolic process GO:0042157 43 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
organic acid transport GO:0015849 101 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
digestive system development GO:0055123 200 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
negative regulation of cell development GO:0010721 169 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.013
blastocyst growth GO:0001832 23 0.013
protein targeting GO:0006605 143 0.013
Fly
lateral inhibition GO:0046331 1 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
divalent inorganic cation transport GO:0072511 178 0.013
viral process GO:0016032 41 0.013
regulation of cell activation GO:0050865 289 0.013
positive regulation of cell activation GO:0050867 158 0.012
positive regulation of ras gtpase activity GO:0032320 65 0.012
positive regulation of cell death GO:0010942 224 0.012
regulation of protein maturation GO:1903317 96 0.012
epithelial cell proliferation GO:0050673 174 0.012
positive regulation of neuron projection development GO:0010976 79 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
Fly
histone lysine methylation GO:0034968 50 0.012
female gamete generation GO:0007292 74 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
cerebral cortex development GO:0021987 86 0.012
learning or memory GO:0007611 148 0.012
vesicle organization GO:0016050 60 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
positive regulation of tor signaling GO:0032008 3 0.012
forebrain development GO:0030900 302 0.012
lipid biosynthetic process GO:0008610 179 0.012
single fertilization GO:0007338 82 0.012
regulation of cell cycle phase transition GO:1901987 77 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
protein palmitoylation GO:0018345 14 0.012
regulation of mapk cascade GO:0043408 248 0.012
locomotory behavior GO:0007626 195 0.012
misfolded protein transport GO:0070843 1 0.012
cellular response to epidermal growth factor stimulus GO:0071364 4 0.012
positive regulation of leukocyte differentiation GO:1902107 86 0.012
mrna splicing via spliceosome GO:0000398 43 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
inflammatory response GO:0006954 244 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
cellular response to peptide GO:1901653 92 0.011
viral transcription GO:0019083 3 0.011
regulation of mrna metabolic process GO:1903311 43 0.011
negative regulation of protein processing GO:0010955 79 0.011
negative regulation of protein maturation GO:1903318 79 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
regulation of protein processing GO:0070613 96 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
cellular protein complex assembly GO:0043623 116 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
regulation of protein kinase activity GO:0045859 232 0.011
positive regulation of cell development GO:0010720 237 0.011
blood vessel morphogenesis GO:0048514 285 0.011
oogenesis GO:0048477 56 0.011
developmental maturation GO:0021700 193 0.011
regulation of transmembrane transport GO:0034762 128 0.011
peptidyl lysine methylation GO:0018022 29 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
regulation of cell growth GO:0001558 91 0.011
wound healing GO:0042060 157 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
phospholipid metabolic process GO:0006644 87 0.011
transition metal ion transport GO:0000041 38 0.011
negative regulation of wnt signaling pathway GO:0030178 73 0.011
interleukin 10 secretion GO:0072608 4 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.011
erythrocyte differentiation GO:0030218 88 0.011
regulation of protein transport GO:0051223 163 0.011
Fly
regulation of interleukin 10 secretion GO:2001179 4 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.010
divalent metal ion transport GO:0070838 172 0.010
inclusion body assembly GO:0070841 3 0.010
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 3 0.010
cytokine mediated signaling pathway GO:0019221 115 0.010
negative regulation of phosphorus metabolic process GO:0010563 184 0.010
cellular chemical homeostasis GO:0055082 215 0.010
cellular response to external stimulus GO:0071496 88 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
dna endoreduplication GO:0042023 4 0.010
multi multicellular organism process GO:0044706 109 0.010
protein polymerization GO:0051258 57 0.010
response to starvation GO:0042594 65 0.010
cellular response to nutrient levels GO:0031669 64 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
glucose homeostasis GO:0042593 128 0.010
positive regulation of transferase activity GO:0051347 167 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
regulation of cell migration GO:0030334 219 0.010
lipid localization GO:0010876 126 0.010
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.010
protein alkylation GO:0008213 81 0.010

Tnpo2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.012
neuropathy DOID:870 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
neuromuscular disease DOID:440 0 0.010