Mus musculus

28 known processes

Scn4b

sodium channel, type IV, beta

(Aliases: Gm1471)

Scn4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.158
cation transmembrane transport GO:0098655 266 0.130
transmembrane transport GO:0055085 412 0.104
cation transport GO:0006812 399 0.102
nucleoside phosphate metabolic process GO:0006753 338 0.076
cation homeostasis GO:0055080 212 0.074
regulation of transmembrane transport GO:0034762 128 0.072
monocarboxylic acid metabolic process GO:0032787 191 0.057
muscle contraction GO:0006936 101 0.053
Human
purine ribonucleotide metabolic process GO:0009150 290 0.051
regulation of nucleotide metabolic process GO:0006140 169 0.048
regulation of ion transport GO:0043269 215 0.046
actin cytoskeleton organization GO:0030036 220 0.046
cellular lipid metabolic process GO:0044255 323 0.045
ribonucleotide metabolic process GO:0009259 291 0.044
regulation of ion transmembrane transport GO:0034765 119 0.043
purine nucleoside metabolic process GO:0042278 241 0.043
cellular divalent inorganic cation homeostasis GO:0072503 127 0.043
amine metabolic process GO:0009308 45 0.042
cellular chemical homeostasis GO:0055082 215 0.041
muscle system process GO:0003012 141 0.041
Human
regulation of purine nucleotide metabolic process GO:1900542 169 0.040
synaptic transmission GO:0007268 329 0.040
nucleotide metabolic process GO:0009117 332 0.038
regulation of nucleoside metabolic process GO:0009118 130 0.038
regulation of protein localization GO:0032880 231 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
purine nucleotide metabolic process GO:0006163 302 0.038
cellular homeostasis GO:0019725 240 0.038
membrane organization GO:0061024 245 0.037
cellular metal ion homeostasis GO:0006875 151 0.037
ribonucleoside metabolic process GO:0009119 245 0.036
action potential GO:0001508 78 0.036
Human
organophosphate catabolic process GO:0046434 232 0.035
metal ion homeostasis GO:0055065 189 0.035
muscle tissue development GO:0060537 308 0.035
regulation of cellular component biogenesis GO:0044087 181 0.034
carbohydrate derivative catabolic process GO:1901136 231 0.034
regulation of purine nucleotide catabolic process GO:0033121 122 0.034
ribonucleoside triphosphate catabolic process GO:0009203 199 0.033
cellular ketone metabolic process GO:0042180 84 0.033
g protein coupled receptor signaling pathway GO:0007186 243 0.033
cardiac muscle contraction GO:0060048 32 0.032
Human
regulation of system process GO:0044057 200 0.032
Human
small gtpase mediated signal transduction GO:0007264 97 0.032
purine containing compound metabolic process GO:0072521 311 0.032
myosin filament assembly GO:0031034 2 0.032
lipid biosynthetic process GO:0008610 179 0.032
ribonucleoside catabolic process GO:0042454 206 0.032
cellular nitrogen compound catabolic process GO:0044270 280 0.031
cytoplasmic transport GO:0016482 234 0.031
negative regulation of immune system process GO:0002683 209 0.031
carbohydrate metabolic process GO:0005975 230 0.031
nucleoside triphosphate metabolic process GO:0009141 230 0.031
inorganic cation transmembrane transport GO:0098662 207 0.031
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
mapk cascade GO:0000165 281 0.030
muscle cell differentiation GO:0042692 261 0.030
organic cyclic compound catabolic process GO:1901361 295 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.030
glycosyl compound catabolic process GO:1901658 206 0.029
striated muscle tissue development GO:0014706 293 0.029
aromatic compound catabolic process GO:0019439 286 0.029
blood circulation GO:0008015 195 0.029
Human
oxidation reduction process GO:0055114 342 0.029
nucleoside metabolic process GO:0009116 246 0.029
regulation of secretion by cell GO:1903530 249 0.028
divalent inorganic cation homeostasis GO:0072507 138 0.028
regulation of hormone levels GO:0010817 211 0.028
striated muscle myosin thick filament assembly GO:0071688 1 0.028
nucleoside phosphate catabolic process GO:1901292 222 0.028
myosin filament organization GO:0031033 3 0.028
regulation of neuron differentiation GO:0045664 281 0.028
anatomical structure homeostasis GO:0060249 145 0.028
striated muscle cell development GO:0055002 125 0.027
heterocycle catabolic process GO:0046700 280 0.027
actin filament based movement GO:0030048 23 0.027
fatty acid metabolic process GO:0006631 121 0.027
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
plasma membrane organization GO:0007009 90 0.027
cellular amino acid metabolic process GO:0006520 103 0.026
positive regulation of hydrolase activity GO:0051345 148 0.026
purine nucleoside triphosphate catabolic process GO:0009146 203 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
ribonucleotide catabolic process GO:0009261 208 0.026
positive regulation of nucleotide metabolic process GO:0045981 114 0.026
regulation of membrane potential GO:0042391 192 0.025
Human
hormone metabolic process GO:0042445 86 0.025
heart process GO:0003015 94 0.025
Human
purine nucleoside catabolic process GO:0006152 205 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
regulation of hydrolase activity GO:0051336 246 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.024
ras protein signal transduction GO:0007265 77 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
sequestering of metal ion GO:0051238 19 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
nitrogen compound transport GO:0071705 271 0.023
neuronal action potential GO:0019228 54 0.023
circulatory system process GO:0003013 197 0.023
Human
regulation of nucleotide catabolic process GO:0030811 122 0.022
regulation of kinase activity GO:0043549 249 0.022
cellular ion homeostasis GO:0006873 165 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
divalent metal ion transport GO:0070838 172 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
purine containing compound catabolic process GO:0072523 213 0.022
organelle assembly GO:0070925 177 0.022
positive regulation of cell development GO:0010720 237 0.021
sodium ion transmembrane transport GO:0035725 49 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
regulation of cell projection organization GO:0031344 206 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
cellular amine metabolic process GO:0044106 44 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
gland development GO:0048732 330 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.021
positive regulation of cellular catabolic process GO:0031331 148 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
response to organic cyclic compound GO:0014070 198 0.021
maintenance of location GO:0051235 89 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
regulation of actin filament based process GO:0032970 99 0.020
Human
homeostasis of number of cells GO:0048872 210 0.020
organic acid transport GO:0015849 101 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
regulation of anatomical structure size GO:0090066 178 0.020
sequestering of calcium ion GO:0051208 18 0.020
calcium ion transmembrane transport GO:0070588 85 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
regulation of metal ion transport GO:0010959 106 0.020
Human
regulation of muscle contraction GO:0006937 49 0.020
Human
negative regulation of intracellular signal transduction GO:1902532 167 0.019
multicellular organismal signaling GO:0035637 91 0.019
Human
hormone secretion GO:0046879 128 0.019
cellular calcium ion homeostasis GO:0006874 119 0.019
apoptotic signaling pathway GO:0097190 306 0.019
divalent inorganic cation transport GO:0072511 178 0.019
regulation of organelle organization GO:0033043 289 0.019
nucleoside monophosphate metabolic process GO:0009123 85 0.019
cellular response to lipid GO:0071396 145 0.019
regulation of transporter activity GO:0032409 57 0.019
Human
positive regulation of programmed cell death GO:0043068 218 0.018
regulation of homeostatic process GO:0032844 182 0.018
single organism cell adhesion GO:0098602 156 0.018
Mouse
leukocyte differentiation GO:0002521 342 0.018
Mouse
calcium ion homeostasis GO:0055074 127 0.018
developmental growth involved in morphogenesis GO:0060560 138 0.018
positive regulation of nervous system development GO:0051962 221 0.018
nucleotide catabolic process GO:0009166 217 0.018
protein localization to membrane GO:0072657 108 0.018
learning or memory GO:0007611 148 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
heart contraction GO:0060047 93 0.017
Human
intracellular protein transport GO:0006886 204 0.017
neurotransmitter transport GO:0006836 76 0.017
microtubule based process GO:0007017 236 0.017
alcohol metabolic process GO:0006066 116 0.017
transmission of nerve impulse GO:0019226 76 0.017
regulation of ion transmembrane transporter activity GO:0032412 54 0.017
Human
muscle cell development GO:0055001 133 0.017
macromolecule catabolic process GO:0009057 281 0.017
small molecule biosynthetic process GO:0044283 132 0.017
regulation of cell cycle GO:0051726 281 0.017
calcium ion transport GO:0006816 159 0.017
glucose transport GO:0015758 56 0.017
protein localization to organelle GO:0033365 185 0.016
striated muscle contraction GO:0006941 45 0.016
Human
regulation of cellular component size GO:0032535 121 0.016
nucleoside catabolic process GO:0009164 206 0.016
regulation of transferase activity GO:0051338 263 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
peptide transport GO:0015833 133 0.016
muscle fiber development GO:0048747 76 0.016
adult locomotory behavior GO:0008344 91 0.016
positive regulation of secretion GO:0051047 130 0.016
cognition GO:0050890 149 0.016
positive regulation of cell death GO:0010942 224 0.016
tube formation GO:0035148 140 0.016
regulation of synaptic plasticity GO:0048167 87 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
regulation of proteolysis GO:0030162 164 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
regulation of ion homeostasis GO:2000021 64 0.015
atp metabolic process GO:0046034 75 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
regulation of mapk cascade GO:0043408 248 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
cellular protein complex assembly GO:0043623 116 0.015
regulation of cytoskeleton organization GO:0051493 122 0.015
axonogenesis GO:0007409 274 0.015
developmental cell growth GO:0048588 84 0.015
respiratory system development GO:0060541 190 0.015
negative regulation of protein modification process GO:0031400 163 0.015
myeloid cell differentiation GO:0030099 233 0.015
cell type specific apoptotic process GO:0097285 268 0.015
dephosphorylation GO:0016311 129 0.015
amide transport GO:0042886 138 0.015
skeletal muscle organ development GO:0060538 163 0.015
long term synaptic potentiation GO:0060291 25 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
protein ubiquitination GO:0016567 171 0.014
wound healing GO:0042060 157 0.014
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
endomembrane system organization GO:0010256 147 0.014
peptidyl amino acid modification GO:0018193 336 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
organelle fission GO:0048285 170 0.014
rho protein signal transduction GO:0007266 32 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
cell adhesion GO:0007155 329 0.014
Mouse
skeletal muscle fiber development GO:0048741 58 0.014
response to radiation GO:0009314 165 0.014
organic anion transport GO:0015711 137 0.014
neuron neuron synaptic transmission GO:0007270 69 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
skin development GO:0043588 220 0.014
mesodermal cell migration GO:0008078 4 0.014
multicellular organismal homeostasis GO:0048871 164 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
carboxylic acid transport GO:0046942 100 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
regulation of neuron projection development GO:0010975 169 0.013
regulation of cell adhesion GO:0030155 154 0.013
protein targeting GO:0006605 143 0.013
sodium ion transport GO:0006814 73 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
positive regulation of neuron projection development GO:0010976 79 0.013
ossification GO:0001503 216 0.013
defecation GO:0030421 1 0.013
epithelial cell proliferation GO:0050673 174 0.013
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
single organismal cell cell adhesion GO:0016337 131 0.013
Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
positive regulation of protein modification process GO:0031401 299 0.013
locomotory behavior GO:0007626 195 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
cell growth GO:0016049 130 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
purine ribonucleotide biosynthetic process GO:0009152 59 0.013
cardiac muscle cell contraction GO:0086003 7 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
t cell activation GO:0042110 289 0.012
Mouse
activation of meiosis involved in egg activation GO:0060466 2 0.012
regulation of chloride transport GO:2001225 2 0.012
neuron apoptotic process GO:0051402 142 0.012
response to nutrient levels GO:0031667 109 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regionalization GO:0003002 337 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
skeletal myofibril assembly GO:0014866 4 0.012
tissue homeostasis GO:0001894 115 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of protein transport GO:0051223 163 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
organic hydroxy compound biosynthetic process GO:1901617 77 0.012
regulation of map kinase activity GO:0043405 120 0.012
sensory organ morphogenesis GO:0090596 242 0.012
cellular potassium ion transport GO:0071804 43 0.012
glycerolipid metabolic process GO:0046486 122 0.012
membrane lipid biosynthetic process GO:0046467 32 0.012
regulation of secretion GO:0051046 274 0.012
regulation of blood circulation GO:1903522 93 0.012
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
developmental maturation GO:0021700 193 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
camera type eye development GO:0043010 266 0.012
organelle localization GO:0051640 179 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
gpi anchor metabolic process GO:0006505 7 0.012
organic hydroxy compound transport GO:0015850 93 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
positive regulation of growth GO:0045927 104 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
negative regulation of nervous system development GO:0051961 156 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
positive regulation of ion transport GO:0043270 65 0.012
Human
negative regulation of phosphorylation GO:0042326 166 0.012
actin mediated cell contraction GO:0070252 15 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
regulation of cell activation GO:0050865 289 0.011
negative regulation of cell development GO:0010721 169 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
steroid metabolic process GO:0008202 119 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
regulation of cell cycle process GO:0010564 160 0.011
epidermis development GO:0008544 187 0.011
forebrain development GO:0030900 302 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
Mouse
glycerophospholipid metabolic process GO:0006650 71 0.011
spermatogenesis GO:0007283 284 0.011
sensory perception GO:0007600 245 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
osteoclast differentiation GO:0030316 62 0.011
mitochondrion organization GO:0007005 134 0.011
nuclear dna replication GO:0033260 3 0.011
nuclear transport GO:0051169 139 0.011
membrane lipid metabolic process GO:0006643 53 0.011
regulation of peptidase activity GO:0052547 96 0.011
cytosolic calcium ion homeostasis GO:0051480 70 0.011
neuron death GO:0070997 154 0.011
organic acid biosynthetic process GO:0016053 86 0.011
male gamete generation GO:0048232 285 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
inclusion body assembly GO:0070841 3 0.010
response to extracellular stimulus GO:0009991 127 0.010
ribose phosphate biosynthetic process GO:0046390 59 0.010
protein catabolic process GO:0030163 221 0.010
purine nucleoside monophosphate catabolic process GO:0009128 58 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
adult behavior GO:0030534 135 0.010
positive regulation of cell adhesion GO:0045785 80 0.010
digestive system development GO:0055123 200 0.010
ribonucleoside monophosphate catabolic process GO:0009158 57 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
peptide hormone secretion GO:0030072 109 0.010
peptide secretion GO:0002790 114 0.010
response to organonitrogen compound GO:0010243 246 0.010
guanosine containing compound metabolic process GO:1901068 144 0.010
blood vessel morphogenesis GO:0048514 285 0.010
myotube cell development GO:0014904 60 0.010
protein maturation GO:0051604 176 0.010
cellular macromolecule catabolic process GO:0044265 206 0.010
regulation of gtp catabolic process GO:0033124 113 0.010
negative regulation of molecular function GO:0044092 258 0.010

Scn4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.046
disease of anatomical entity DOID:7 0 0.046
muscular disease DOID:0080000 0 0.032
musculoskeletal system disease DOID:17 0 0.032
muscle tissue disease DOID:66 0 0.032
cardiovascular system disease DOID:1287 0 0.024
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.015
central nervous system disease DOID:331 0 0.014
sensory system disease DOID:0050155 0 0.013
myopathy DOID:423 0 0.013
disease of metabolism DOID:0014667 0 0.012
heart disease DOID:114 0 0.010
cardiomyopathy DOID:0050700 0 0.010