Mus musculus

81 known processes

Grem2

gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)

(Aliases: Gremlin2,Prdc)

Grem2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
urogenital system development GO:0001655 261 0.184
regulation of system process GO:0044057 200 0.178
regulation of defense response GO:0031347 233 0.159
renal system development GO:0072001 225 0.151
immune effector process GO:0002252 321 0.116
gland development GO:0048732 330 0.112
response to organonitrogen compound GO:0010243 246 0.112
cytokine production GO:0001816 319 0.111
positive regulation of cellular amine metabolic process GO:0033240 5 0.105
negative regulation of immune system process GO:0002683 209 0.103
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.086
organonitrogen compound biosynthetic process GO:1901566 192 0.084
regulation of cytokine production GO:0001817 266 0.083
sensory perception of pain GO:0019233 47 0.077
sensory organ morphogenesis GO:0090596 242 0.076
g protein coupled receptor signaling pathway GO:0007186 243 0.076
regulation of epithelial cell proliferation GO:0050678 141 0.075
digestive tract development GO:0048565 190 0.074
negative regulation of cell proliferation GO:0008285 296 0.073
neuron projection extension GO:1990138 64 0.073
cellular lipid metabolic process GO:0044255 323 0.072
negative regulation of endothelial cell migration GO:0010596 4 0.069
nephron development GO:0072006 109 0.068
branching morphogenesis of an epithelial tube GO:0048754 159 0.068
lipid biosynthetic process GO:0008610 179 0.067
angiogenesis GO:0001525 201 0.067
multicellular organism growth GO:0035264 161 0.067
developmental growth involved in morphogenesis GO:0060560 138 0.065
blood circulation GO:0008015 195 0.064
dna metabolic process GO:0006259 303 0.064
positive regulation of kinase activity GO:0033674 155 0.064
cellular ketone metabolic process GO:0042180 84 0.059
circulatory system process GO:0003013 197 0.059
response to organic cyclic compound GO:0014070 198 0.059
defense response to other organism GO:0098542 197 0.058
positive regulation of cell adhesion GO:0045785 80 0.058
wound healing GO:0042060 157 0.058
forebrain development GO:0030900 302 0.057
regulation of secretion by cell GO:1903530 249 0.055
muscle cell differentiation GO:0042692 261 0.055
response to extracellular stimulus GO:0009991 127 0.054
regionalization GO:0003002 337 0.054
regulation of lymphocyte activation GO:0051249 240 0.054
regulation of cell motility GO:2000145 236 0.054
sensory perception GO:0007600 245 0.054
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.054
neuron projection guidance GO:0097485 141 0.053
regulation of secretion GO:0051046 274 0.053
monocarboxylic acid metabolic process GO:0032787 191 0.053
regulation of blood pressure GO:0008217 93 0.052
positive regulation of cytokine production GO:0001819 174 0.052
telencephalon development GO:0021537 186 0.052
cellular chemical homeostasis GO:0055082 215 0.051
regulation of hormone levels GO:0010817 211 0.051
digestive system development GO:0055123 200 0.050
inflammatory response GO:0006954 244 0.050
apoptotic signaling pathway GO:0097190 306 0.050
regulation of cell adhesion GO:0030155 154 0.049
endothelial cell migration GO:0043542 44 0.048
female sex differentiation GO:0046660 84 0.048
regulation of chemotaxis GO:0050920 53 0.047
camera type eye development GO:0043010 266 0.047
digestive tract morphogenesis GO:0048546 147 0.047
cellular divalent inorganic cation homeostasis GO:0072503 127 0.047
regulation of ion transport GO:0043269 215 0.047
positive regulation of nervous system development GO:0051962 221 0.046
chemotaxis GO:0006935 247 0.046
detection of stimulus GO:0051606 84 0.046
midgut development GO:0007494 4 0.046
positive regulation of cellular component biogenesis GO:0044089 94 0.046
positive regulation of phospholipase activity GO:0010518 3 0.045
morphogenesis of a branching structure GO:0001763 203 0.044
hematopoietic progenitor cell differentiation GO:0002244 143 0.043
negative regulation of multi organism process GO:0043901 68 0.043
cellular response to hormone stimulus GO:0032870 150 0.043
regulation of cellular ketone metabolic process GO:0010565 66 0.043
cytokine mediated signaling pathway GO:0019221 115 0.042
hindbrain development GO:0030902 128 0.042
regulation of protein kinase activity GO:0045859 232 0.042
nucleotide metabolic process GO:0009117 332 0.041
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.040
sequestering of calcium ion GO:0051208 18 0.039
small molecule biosynthetic process GO:0044283 132 0.039
fatty acid metabolic process GO:0006631 121 0.039
epithelium migration GO:0090132 63 0.039
vascular process in circulatory system GO:0003018 62 0.039
ameboidal type cell migration GO:0001667 128 0.039
regulation of anatomical structure size GO:0090066 178 0.039
response to peptide hormone GO:0043434 127 0.038
regulation of vesicle mediated transport GO:0060627 139 0.038
cellular amino acid metabolic process GO:0006520 103 0.038
cellular response to cytokine stimulus GO:0071345 189 0.038
response to lipopolysaccharide GO:0032496 128 0.038
carbohydrate metabolic process GO:0005975 230 0.037
cytosolic calcium ion homeostasis GO:0051480 70 0.037
positive regulation of angiogenesis GO:0045766 46 0.037
regulation of cell activation GO:0050865 289 0.037
development of primary sexual characteristics GO:0045137 143 0.036
organ growth GO:0035265 117 0.036
kidney development GO:0001822 213 0.036
retina development in camera type eye GO:0060041 119 0.036
cellular response to growth factor stimulus GO:0071363 197 0.036
endomembrane system organization GO:0010256 147 0.036
response to molecule of bacterial origin GO:0002237 143 0.036
myeloid leukocyte mediated immunity GO:0002444 42 0.035
regulation of cell migration GO:0030334 219 0.035
metencephalon development GO:0022037 89 0.035
negative regulation of protein metabolic process GO:0051248 282 0.035
female gonad development GO:0008585 71 0.035
cellular calcium ion homeostasis GO:0006874 119 0.035
gonad development GO:0008406 141 0.034
cell growth GO:0016049 130 0.034
negative regulation of cellular protein metabolic process GO:0032269 247 0.034
cell chemotaxis GO:0060326 81 0.034
cellular amine metabolic process GO:0044106 44 0.034
regulation of organelle organization GO:0033043 289 0.034
locomotory behavior GO:0007626 195 0.034
purine nucleoside metabolic process GO:0042278 241 0.034
regulation of cell projection organization GO:0031344 206 0.033
maintenance of location GO:0051235 89 0.033
cytokine metabolic process GO:0042107 71 0.033
cell adhesion GO:0007155 329 0.033
skeletal system development GO:0001501 356 0.033
regulation of multi organism process GO:0043900 111 0.033
placenta development GO:0001890 140 0.033
muscle tissue development GO:0060537 308 0.032
positive regulation of immune effector process GO:0002699 107 0.032
calcium ion homeostasis GO:0055074 127 0.032
regulation of vasculature development GO:1901342 88 0.032
response to alcohol GO:0097305 48 0.032
epithelial tube morphogenesis GO:0060562 303 0.032
adult behavior GO:0030534 135 0.032
regulation of mapk cascade GO:0043408 248 0.032
regulation of inflammatory response GO:0050727 147 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.032
learning or memory GO:0007611 148 0.032
regulation of morphogenesis of a branching structure GO:0060688 53 0.032
regulation of monocyte chemotaxis GO:0090025 3 0.031
axonogenesis GO:0007409 274 0.031
cellular protein complex assembly GO:0043623 116 0.031
meiotic cell cycle GO:0051321 122 0.031
germ cell development GO:0007281 185 0.031
cation homeostasis GO:0055080 212 0.030
protein processing GO:0016485 163 0.030
developmental cell growth GO:0048588 84 0.030
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.030
organonitrogen compound catabolic process GO:1901565 264 0.029
synapse organization GO:0050808 125 0.029
cellular homeostasis GO:0019725 240 0.029
axon guidance GO:0007411 141 0.029
cell type specific apoptotic process GO:0097285 268 0.029
regulation of kinase activity GO:0043549 249 0.029
hormone metabolic process GO:0042445 86 0.029
nitrogen compound transport GO:0071705 271 0.029
kidney epithelium development GO:0072073 121 0.029
negative regulation of growth GO:0045926 99 0.028
cation transmembrane transport GO:0098655 266 0.028
wnt signaling pathway GO:0016055 188 0.028
nuclear division GO:0000280 158 0.028
homeostasis of number of cells GO:0048872 210 0.028
oxidation reduction process GO:0055114 342 0.028
myeloid cell differentiation GO:0030099 233 0.028
cell recognition GO:0008037 83 0.028
morphogenesis of a branching epithelium GO:0061138 193 0.028
cellular response to lipid GO:0071396 145 0.028
regulation of cellular response to growth factor stimulus GO:0090287 82 0.027
nephron morphogenesis GO:0072028 69 0.027
mitotic cell cycle GO:0000278 195 0.027
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 3 0.027
innate immune response GO:0045087 157 0.027
regulation of neuron projection development GO:0010975 169 0.027
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
male gamete generation GO:0048232 285 0.027
calcium ion transport GO:0006816 159 0.027
multi multicellular organism process GO:0044706 109 0.027
response to acid chemical GO:0001101 111 0.027
transmembrane transport GO:0055085 412 0.026
negative regulation of hormone metabolic process GO:0032351 4 0.026
leukocyte differentiation GO:0002521 342 0.026
gastrulation GO:0007369 116 0.026
somite development GO:0061053 81 0.026
regulation of endothelial cell migration GO:0010594 22 0.026
divalent metal ion transport GO:0070838 172 0.026
single organism cell adhesion GO:0098602 156 0.026
acute inflammatory response GO:0002526 41 0.026
striated muscle tissue development GO:0014706 293 0.026
ribonucleotide metabolic process GO:0009259 291 0.026
negative regulation of cell migration GO:0030336 59 0.026
positive regulation of transferase activity GO:0051347 167 0.026
inorganic cation transmembrane transport GO:0098662 207 0.026
cellular response to extracellular stimulus GO:0031668 81 0.025
bone development GO:0060348 120 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
positive regulation of cell migration GO:0030335 109 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
regulation of mitotic cell cycle GO:0007346 126 0.025
positive regulation of cell motility GO:2000147 116 0.025
regulation of transferase activity GO:0051338 263 0.025
mesoderm development GO:0007498 100 0.025
tissue migration GO:0090130 68 0.025
ribose phosphate metabolic process GO:0019693 291 0.024
stem cell differentiation GO:0048863 268 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.024
membrane organization GO:0061024 245 0.024
central nervous system neuron differentiation GO:0021953 162 0.024
steroid metabolic process GO:0008202 119 0.024
regulation of body fluid levels GO:0050878 162 0.024
lymphocyte proliferation GO:0046651 164 0.024
regulation of cell growth GO:0001558 91 0.024
organophosphate biosynthetic process GO:0090407 122 0.024
organic hydroxy compound metabolic process GO:1901615 203 0.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.023
positive regulation of epithelial cell proliferation GO:0050679 68 0.023
amine metabolic process GO:0009308 45 0.023
peptidyl amino acid modification GO:0018193 336 0.023
regulation of protein localization GO:0032880 231 0.023
positive regulation of protein kinase activity GO:0045860 144 0.023
protein localization to nucleus GO:0034504 121 0.023
muscle system process GO:0003012 141 0.023
cellular response to external stimulus GO:0071496 88 0.023
cellular ion homeostasis GO:0006873 165 0.023
exocytosis GO:0006887 121 0.023
second messenger mediated signaling GO:0019932 73 0.023
regulation of cell cycle GO:0051726 281 0.023
regulation of acute inflammatory response GO:0002673 27 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
steroid biosynthetic process GO:0006694 47 0.022
positive regulation of synapse assembly GO:0051965 18 0.022
lung development GO:0030324 164 0.022
camp biosynthetic process GO:0006171 31 0.022
response to steroid hormone GO:0048545 56 0.022
epithelial cell proliferation GO:0050673 174 0.022
regulation of proteolysis GO:0030162 164 0.022
regulation of tube size GO:0035150 57 0.022
blood vessel morphogenesis GO:0048514 285 0.022
regulation of protein secretion GO:0050708 82 0.022
regulation of erk1 and erk2 cascade GO:0070372 71 0.022
carbohydrate homeostasis GO:0033500 128 0.022
positive regulation of camp mediated signaling GO:0043950 3 0.022
alcohol metabolic process GO:0006066 116 0.022
actin filament based movement GO:0030048 23 0.022
negative regulation of reproductive process GO:2000242 31 0.022
organelle fission GO:0048285 170 0.022
adult locomotory behavior GO:0008344 91 0.022
vitamin d biosynthetic process GO:0042368 3 0.022
rhythmic process GO:0048511 174 0.021
response to nutrient levels GO:0031667 109 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
development of primary female sexual characteristics GO:0046545 73 0.021
chemokine mediated signaling pathway GO:0070098 17 0.021
neuron migration GO:0001764 122 0.021
regulation of blood circulation GO:1903522 93 0.021
cellular response to gonadotropin stimulus GO:0071371 4 0.021
cerebellum development GO:0021549 77 0.021
regulation of angiogenesis GO:0045765 81 0.021
defense response to bacterium GO:0042742 119 0.021
positive regulation of chemotaxis GO:0050921 38 0.021
positive regulation of protein modification process GO:0031401 299 0.021
spermatogenesis GO:0007283 284 0.021
limb development GO:0060173 166 0.021
pallium development GO:0021543 120 0.021
protein maturation GO:0051604 176 0.021
morphogenesis of embryonic epithelium GO:0016331 159 0.021
embryonic organ morphogenesis GO:0048562 276 0.021
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.020
positive regulation of smooth muscle cell migration GO:0014911 4 0.020
regulation of cell size GO:0008361 72 0.020
diencephalon development GO:0021536 63 0.020
metal ion homeostasis GO:0055065 189 0.020
chromosome segregation GO:0007059 48 0.020
regulation of blood vessel size GO:0050880 56 0.020
positive regulation of protein secretion GO:0050714 52 0.020
glycoprotein biosynthetic process GO:0009101 89 0.020
nucleoside metabolic process GO:0009116 246 0.020
positive regulation of behavior GO:0048520 40 0.020
regulation of axon guidance GO:1902667 13 0.019
regulation of lipid metabolic process GO:0019216 118 0.019
neural precursor cell proliferation GO:0061351 121 0.019
positive regulation of defense response GO:0031349 124 0.019
leukocyte chemotaxis GO:0030595 69 0.019
cellular response to alcohol GO:0097306 23 0.019
endochondral bone morphogenesis GO:0060350 50 0.019
negative regulation of hormone biosynthetic process GO:0032353 4 0.019
macromolecule catabolic process GO:0009057 281 0.019
chromatin modification GO:0016568 187 0.019
respiratory tube development GO:0030323 167 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
regulation of testosterone biosynthetic process GO:2000224 2 0.019
carbohydrate biosynthetic process GO:0016051 74 0.019
regulation of hydrolase activity GO:0051336 246 0.019
positive regulation of cell substrate adhesion GO:0010811 47 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
genitalia development GO:0048806 37 0.019
regulation of cell substrate adhesion GO:0010810 73 0.019
cytoplasmic transport GO:0016482 234 0.019
appendage morphogenesis GO:0035107 149 0.019
positive regulation of endothelial cell proliferation GO:0001938 17 0.019
leukocyte mediated immunity GO:0002443 174 0.018
lymphocyte differentiation GO:0030098 242 0.018
response to radiation GO:0009314 165 0.018
ion transmembrane transport GO:0034220 361 0.018
endocytosis GO:0006897 168 0.018
activin receptor signaling pathway GO:0032924 18 0.018
regulation of homeostatic process GO:0032844 182 0.018
somatotropin secreting cell differentiation GO:0060126 4 0.018
humoral immune response GO:0006959 57 0.018
single organismal cell cell adhesion GO:0016337 131 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
cellular response to organic cyclic compound GO:0071407 87 0.018
cation transport GO:0006812 399 0.018
kidney morphogenesis GO:0060993 83 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
regulation of response to wounding GO:1903034 189 0.018
endothelial cell proliferation GO:0001935 27 0.018
hormone secretion GO:0046879 128 0.018
circadian rhythm GO:0007623 114 0.017
negative regulation of immune effector process GO:0002698 55 0.017
response to hypoxia GO:0001666 58 0.017
plasma membrane organization GO:0007009 90 0.017
response to oxygen levels GO:0070482 62 0.017
response to growth factor GO:0070848 198 0.017
regulation of renal sodium excretion GO:0035813 3 0.017
muscle fiber development GO:0048747 76 0.017
lipid localization GO:0010876 126 0.017
regulation of neurological system process GO:0031644 22 0.017
t cell activation GO:0042110 289 0.017
cell matrix adhesion GO:0007160 68 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
embryonic skeletal system morphogenesis GO:0048704 91 0.017
glycerophospholipid metabolic process GO:0006650 71 0.017
neuron death GO:0070997 154 0.017
negative regulation of defense response GO:0031348 77 0.017
embryonic skeletal system development GO:0048706 120 0.017
cellular response to inorganic substance GO:0071241 37 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.016
ribonucleotide biosynthetic process GO:0009260 59 0.016
regulation of fat cell differentiation GO:0045598 81 0.016
positive regulation of phospholipase c activity GO:0010863 2 0.016
negative regulation of blood vessel morphogenesis GO:2000181 25 0.016
regulation of neuron differentiation GO:0045664 281 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
establishment of tissue polarity GO:0007164 28 0.016
positive regulation of secretion by cell GO:1903532 114 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
divalent inorganic cation transport GO:0072511 178 0.016
negative regulation of secretion by cell GO:1903531 54 0.016
positive regulation of lymphocyte activation GO:0051251 140 0.016
stem cell development GO:0048864 219 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
regulation of leukocyte mediated immunity GO:0002703 104 0.016
cell division GO:0051301 120 0.016
regulation of organ growth GO:0046620 61 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
i kappab kinase nf kappab signaling GO:0007249 85 0.016
interspecies interaction between organisms GO:0044419 83 0.016
endothelium development GO:0003158 45 0.016
peptidyl tyrosine modification GO:0018212 145 0.016
organophosphate catabolic process GO:0046434 232 0.016
aromatic compound catabolic process GO:0019439 286 0.016
activation of immune response GO:0002253 138 0.016
regulation of endocytosis GO:0030100 69 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
smooth muscle cell chemotaxis GO:0071670 2 0.016
cognition GO:0050890 149 0.016
negative regulation of cell motility GO:2000146 61 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
mesonephric duct morphogenesis GO:0072180 4 0.015
response to corticosterone GO:0051412 1 0.015
glucose homeostasis GO:0042593 128 0.015
tissue remodeling GO:0048771 102 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.015
developmental maturation GO:0021700 193 0.015
regulation of systemic arterial blood pressure GO:0003073 61 0.015
organic hydroxy compound biosynthetic process GO:1901617 77 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
regulation of interleukin 6 production GO:0032675 55 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.015
regulation of endothelial cell proliferation GO:0001936 23 0.015
inner ear morphogenesis GO:0042472 101 0.015
limb morphogenesis GO:0035108 149 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
renal tubule development GO:0061326 87 0.015
regulation of muscle system process GO:0090257 80 0.015
peptidyl serine phosphorylation GO:0018105 74 0.015
mesonephros development GO:0001823 97 0.015
nephron tubule development GO:0072080 84 0.015
telencephalon cell migration GO:0022029 55 0.015
ossification GO:0001503 216 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
protein secretion GO:0009306 111 0.015
positive regulation of cell development GO:0010720 237 0.015
lipid catabolic process GO:0016042 69 0.015
erk1 and erk2 cascade GO:0070371 77 0.015
synaptic transmission GO:0007268 329 0.015
male sex differentiation GO:0046661 109 0.015
negative regulation of cell activation GO:0050866 111 0.015
regulation of cellular response to stress GO:0080135 159 0.015
positive regulation of cell activation GO:0050867 158 0.015
regulation of wnt signaling pathway GO:0030111 123 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
mesenchyme development GO:0060485 152 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
multicellular organismal signaling GO:0035637 91 0.015
chromatin organization GO:0006325 206 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
social behavior GO:0035176 21 0.014
amide transport GO:0042886 138 0.014
cellular response to abiotic stimulus GO:0071214 56 0.014
regulation of membrane potential GO:0042391 192 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
t cell differentiation GO:0030217 174 0.014
glycerolipid metabolic process GO:0046486 122 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
vasoconstriction GO:0042310 27 0.014
synapse assembly GO:0007416 56 0.014
regulation of ion homeostasis GO:2000021 64 0.014
mitotic cytokinesis GO:0000281 4 0.014
response to mineralocorticoid GO:0051385 1 0.014
epithelial cell migration GO:0010631 63 0.014
leukocyte migration GO:0050900 124 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
organic acid biosynthetic process GO:0016053 86 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
cofactor metabolic process GO:0051186 80 0.014
meiotic nuclear division GO:0007126 115 0.014
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.014
positive regulation of cell death GO:0010942 224 0.014
asymmetric neuroblast division GO:0055059 1 0.014
retinal ganglion cell axon guidance GO:0031290 18 0.014
response to inorganic substance GO:0010035 96 0.014
leukocyte proliferation GO:0070661 172 0.014
negative regulation of homeostatic process GO:0032845 71 0.014
regulation of protein catabolic process GO:0042176 108 0.014
covalent chromatin modification GO:0016569 163 0.014
lung alveolus development GO:0048286 45 0.014
renal sodium excretion GO:0035812 3 0.014
protein localization to membrane GO:0072657 108 0.013
protein oligomerization GO:0051259 67 0.013
bmp signaling pathway GO:0030509 93 0.013
regulation of intracellular transport GO:0032386 159 0.013
positive regulation of secretion GO:0051047 130 0.013
cyclic purine nucleotide metabolic process GO:0052652 43 0.013
immune response activating signal transduction GO:0002757 116 0.013
endothelial cell differentiation GO:0045446 41 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
interleukin 6 production GO:0032635 58 0.013
axon extension involved in axon guidance GO:0048846 14 0.013
organelle localization GO:0051640 179 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
response to water GO:0009415 1 0.013
glycoprotein metabolic process GO:0009100 116 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
regulation of cellular component size GO:0032535 121 0.013
positive regulation of ion transport GO:0043270 65 0.013
response to amino acid GO:0043200 37 0.013
activation of phospholipase c activity GO:0007202 2 0.013
female gamete generation GO:0007292 74 0.013
histone modification GO:0016570 159 0.013
regulation of adaptive immune response GO:0002819 90 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
regulation of fibroblast proliferation GO:0048145 34 0.013
cartilage development GO:0051216 140 0.013
neuron neuron synaptic transmission GO:0007270 69 0.013
negative regulation of camp mediated signaling GO:0043951 3 0.013
skin morphogenesis GO:0043589 38 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
negative regulation of protein processing GO:0010955 79 0.013
response to glucocorticoid GO:0051384 20 0.013
regulation of protein kinase b signaling GO:0051896 56 0.013
myeloid leukocyte activation GO:0002274 83 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
skeletal system morphogenesis GO:0048705 203 0.013
regulation of b cell activation GO:0050864 81 0.013
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.013
skeletal muscle organ development GO:0060538 163 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
negative regulation of response to wounding GO:1903035 77 0.013
mitotic cell cycle process GO:1903047 159 0.013
trunk neural crest cell migration GO:0036484 4 0.013
nephron tubule morphogenesis GO:0072078 68 0.012
olfactory learning GO:0008355 2 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
cardiac muscle tissue development GO:0048738 130 0.012
regulation of peptidase activity GO:0052547 96 0.012
body fluid secretion GO:0007589 53 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
regulation of phospholipase c activity GO:1900274 3 0.012

Grem2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
central nervous system disease DOID:331 0 0.029
vascular disease DOID:178 0 0.023
cardiovascular system disease DOID:1287 0 0.023
musculoskeletal system disease DOID:17 0 0.016