Mus musculus

431 known processes

Grem1

gremlin 1

(Aliases: ld,Drm,Cktsf1b1)

Grem1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
urogenital system development GO:0001655 261 0.932
embryonic organ morphogenesis GO:0048562 276 0.880
morphogenesis of a branching epithelium GO:0061138 193 0.820
axonogenesis GO:0007409 274 0.812
appendage development GO:0048736 166 0.791
kidney development GO:0001822 213 0.782
ureteric bud development GO:0001657 94 0.782
mesonephric tubule development GO:0072164 94 0.778
kidney epithelium development GO:0072073 121 0.748
stem cell maintenance GO:0019827 130 0.746
embryonic limb morphogenesis GO:0030326 126 0.732
ureteric bud morphogenesis GO:0060675 62 0.731
lymphocyte differentiation GO:0030098 242 0.704
renal tubule development GO:0061326 87 0.696
mesonephros development GO:0001823 97 0.694
branching morphogenesis of an epithelial tube GO:0048754 159 0.675
developmental growth involved in morphogenesis GO:0060560 138 0.650
Mouse
skeletal system morphogenesis GO:0048705 203 0.626
Human Mouse
mesonephric epithelium development GO:0072163 94 0.553
gastrulation GO:0007369 116 0.547
Mouse
appendage morphogenesis GO:0035107 149 0.544
bone morphogenesis GO:0060349 78 0.534
Mouse
cartilage development GO:0051216 140 0.529
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.512
forelimb morphogenesis GO:0035136 40 0.509
regulation of neuron projection development GO:0010975 169 0.507
ear development GO:0043583 200 0.503
endochondral bone morphogenesis GO:0060350 50 0.487
Mouse
limb morphogenesis GO:0035108 149 0.485
inflammatory response GO:0006954 244 0.481
axon guidance GO:0007411 141 0.474
regulation of defense response GO:0031347 233 0.464
skeletal system development GO:0001501 356 0.464
Human Mouse
nephron morphogenesis GO:0072028 69 0.454
response to growth factor GO:0070848 198 0.454
Mouse
forebrain development GO:0030900 302 0.444
regulation of cellular ketone metabolic process GO:0010565 66 0.442
morphogenesis of a branching structure GO:0001763 203 0.432
positive regulation of cell development GO:0010720 237 0.428
Mouse
connective tissue development GO:0061448 179 0.427
Mouse
ear morphogenesis GO:0042471 118 0.427
sensory organ morphogenesis GO:0090596 242 0.420
cellular amine metabolic process GO:0044106 44 0.414
bone development GO:0060348 120 0.413
Human Mouse
limb development GO:0060173 166 0.412
neuron projection guidance GO:0097485 141 0.412
negative regulation of cell proliferation GO:0008285 296 0.400
Human Mouse
stem cell development GO:0048864 219 0.391
Human
gliogenesis GO:0042063 141 0.384
renal system development GO:0072001 225 0.371
mesonephric tubule morphogenesis GO:0072171 63 0.355
angiogenesis GO:0001525 201 0.355
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.351
sensory perception GO:0007600 245 0.335
cardiac septum development GO:0003279 59 0.330
Mouse
stem cell differentiation GO:0048863 268 0.323
epithelial cell proliferation GO:0050673 174 0.312
bmp signaling pathway GO:0030509 93 0.311
digestive tract development GO:0048565 190 0.304
Mouse
regulation of neuron differentiation GO:0045664 281 0.301
Mouse
nephron tubule morphogenesis GO:0072078 68 0.287
branching involved in ureteric bud morphogenesis GO:0001658 56 0.285
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.283
Mouse
digestive system development GO:0055123 200 0.280
Mouse
heart morphogenesis GO:0003007 178 0.280
apoptotic signaling pathway GO:0097190 306 0.276
telencephalon cell migration GO:0022029 55 0.276
regionalization GO:0003002 337 0.269
cardiac ventricle development GO:0003231 83 0.263
Mouse
telencephalon development GO:0021537 186 0.259
lung development GO:0030324 164 0.259
diencephalon development GO:0021536 63 0.259
epidermis development GO:0008544 187 0.257
epithelial tube morphogenesis GO:0060562 303 0.257
positive regulation of programmed cell death GO:0043068 218 0.256
sensory perception of pain GO:0019233 47 0.249
regulation of inflammatory response GO:0050727 147 0.244
regulation of homeostatic process GO:0032844 182 0.244
positive regulation of apoptotic process GO:0043065 217 0.239
kidney morphogenesis GO:0060993 83 0.237
cellular ketone metabolic process GO:0042180 84 0.234
peptidyl amino acid modification GO:0018193 336 0.234
regulation of cell migration GO:0030334 219 0.232
Mouse
neuron migration GO:0001764 122 0.230
nephron tubule development GO:0072080 84 0.227
cardiac chamber morphogenesis GO:0003206 93 0.225
cellular response to growth factor stimulus GO:0071363 197 0.224
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.223
positive regulation of nervous system development GO:0051962 221 0.222
Mouse
gland development GO:0048732 330 0.222
blood vessel morphogenesis GO:0048514 285 0.221
regulation of apoptotic signaling pathway GO:2001233 197 0.220
ossification GO:0001503 216 0.218
Human
respiratory system development GO:0060541 190 0.212
embryonic forelimb morphogenesis GO:0035115 32 0.211
neuron projection extension GO:1990138 64 0.210
amine metabolic process GO:0009308 45 0.207
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.207
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.202
regulation of secretion GO:0051046 274 0.199
small molecule biosynthetic process GO:0044283 132 0.196
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.196
trachea cartilage morphogenesis GO:0060535 4 0.195
negative regulation of cytokine production GO:0001818 84 0.186
odontogenesis GO:0042476 78 0.185
nephron epithelium morphogenesis GO:0072088 68 0.184
digestive tract morphogenesis GO:0048546 147 0.184
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.183
Human
nephron epithelium development GO:0072009 92 0.179
embryonic appendage morphogenesis GO:0035113 126 0.179
glial cell differentiation GO:0010001 131 0.174
molting cycle GO:0042303 90 0.173
regulation of protein transport GO:0051223 163 0.173
hindbrain development GO:0030902 128 0.170
regulation of organ morphogenesis GO:2000027 144 0.170
metanephros development GO:0001656 79 0.167
pallium development GO:0021543 120 0.165
central nervous system neuron differentiation GO:0021953 162 0.164
transmembrane transport GO:0055085 412 0.162
cation transmembrane transport GO:0098655 266 0.159
male sex differentiation GO:0046661 109 0.159
forebrain cell migration GO:0021885 58 0.159
negative regulation of epithelial cell proliferation GO:0050680 64 0.159
wnt signaling pathway GO:0016055 188 0.158
Human
leukocyte proliferation GO:0070661 172 0.158
Human
formation of primary germ layer GO:0001704 77 0.157
regulation of epithelial cell proliferation GO:0050678 141 0.157
regulation of response to wounding GO:1903034 189 0.154
regulation of chondrocyte differentiation GO:0032330 33 0.154
chondrocyte differentiation GO:0002062 72 0.153
cerebral cortex development GO:0021987 86 0.150
embryonic digit morphogenesis GO:0042733 56 0.150
regulation of cellular response to growth factor stimulus GO:0090287 82 0.149
Mouse
positive regulation of neuron projection development GO:0010976 79 0.148
steroid metabolic process GO:0008202 119 0.147
metanephric nephron development GO:0072210 34 0.145
striated muscle tissue development GO:0014706 293 0.144
regulation of system process GO:0044057 200 0.144
extracellular structure organization GO:0043062 148 0.141
Human
cell fate commitment GO:0045165 210 0.138
divalent metal ion transport GO:0070838 172 0.137
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.137
regulation of cytokine production GO:0001817 266 0.136
t cell activation GO:0042110 289 0.135
positive regulation of neuron differentiation GO:0045666 141 0.133
Mouse
inner ear morphogenesis GO:0042472 101 0.133
skin development GO:0043588 220 0.132
neuronal action potential GO:0019228 54 0.132
limbic system development GO:0021761 72 0.132
motor neuron axon guidance GO:0008045 26 0.130
camera type eye development GO:0043010 266 0.129
cardiac muscle tissue morphogenesis GO:0055008 44 0.129
response to acid chemical GO:0001101 111 0.128
spinal cord development GO:0021510 81 0.128
regulation of cellular amino acid metabolic process GO:0006521 5 0.127
canonical wnt signaling pathway GO:0060070 130 0.127
Human
nephron development GO:0072006 109 0.126
lymphocyte proliferation GO:0046651 164 0.126
cellular amino acid metabolic process GO:0006520 103 0.124
cation transport GO:0006812 399 0.123
myeloid cell differentiation GO:0030099 233 0.123
lung cell differentiation GO:0060479 30 0.122
positive regulation of protein modification process GO:0031401 299 0.122
muscle tissue morphogenesis GO:0060415 53 0.122
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.121
regulation of transmembrane transport GO:0034762 128 0.121
axis elongation involved in somitogenesis GO:0090245 4 0.120
positive regulation of lymphocyte activation GO:0051251 140 0.120
signal transduction in absence of ligand GO:0038034 55 0.119
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.119
cerebral cortex cell migration GO:0021795 44 0.119
cellular chemical homeostasis GO:0055082 215 0.115
hindlimb morphogenesis GO:0035137 42 0.113
central nervous system neuron development GO:0021954 67 0.113
extracellular matrix organization GO:0030198 147 0.112
Human
ameboidal type cell migration GO:0001667 128 0.111
response to organonitrogen compound GO:0010243 246 0.111
positive regulation of cellular amine metabolic process GO:0033240 5 0.111
epithelial cell development GO:0002064 159 0.110
cardiocyte differentiation GO:0035051 87 0.107
circulatory system process GO:0003013 197 0.107
olfactory bulb interneuron development GO:0021891 7 0.107
fat cell differentiation GO:0045444 160 0.107
bronchiole development GO:0060435 3 0.106
negative regulation of cell development GO:0010721 169 0.106
lipid biosynthetic process GO:0008610 179 0.105
ion transmembrane transport GO:0034220 361 0.105
development of primary male sexual characteristics GO:0046546 88 0.103
development of primary sexual characteristics GO:0045137 143 0.102
alcohol metabolic process GO:0006066 116 0.102
calcium ion transport GO:0006816 159 0.101
maintenance of location GO:0051235 89 0.101
Mouse
tube formation GO:0035148 140 0.101
odontogenesis of dentin containing tooth GO:0042475 66 0.101
protein localization to membrane GO:0072657 108 0.100
neural precursor cell proliferation GO:0061351 121 0.100
regulation of cell motility GO:2000145 236 0.100
Mouse
acetylcholine secretion neurotransmission GO:0014055 2 0.100
sequestering of metal ion GO:0051238 19 0.099
regulation of interleukin 1 beta production GO:0032651 25 0.099
mesenchymal cell proliferation GO:0010463 44 0.099
midbrain development GO:0030901 35 0.098
chemotaxis GO:0006935 247 0.098
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.098
cardiac chamber development GO:0003205 108 0.096
Mouse
positive regulation of keratinocyte proliferation GO:0010838 4 0.096
cellular homeostasis GO:0019725 240 0.094
tissue remodeling GO:0048771 102 0.094
Human
extrinsic apoptotic signaling pathway GO:0097191 126 0.093
regulation of ion transmembrane transport GO:0034765 119 0.093
response to extracellular stimulus GO:0009991 127 0.092
leukocyte differentiation GO:0002521 342 0.092
response to molecule of bacterial origin GO:0002237 143 0.091
regulation of ossification GO:0030278 112 0.091
Human
hindbrain morphogenesis GO:0021575 46 0.090
hair follicle development GO:0001942 85 0.090
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.090
cerebellum development GO:0021549 77 0.090
organ growth GO:0035265 117 0.089
Mouse
exocrine system development GO:0035272 45 0.089
sensory perception of mechanical stimulus GO:0050954 107 0.089
regulation of hormone levels GO:0010817 211 0.089
biomineral tissue development GO:0031214 64 0.088
Human
mesoderm development GO:0007498 100 0.088
Mouse
gonad development GO:0008406 141 0.087
cell differentiation in spinal cord GO:0021515 53 0.087
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.087
lung alveolus development GO:0048286 45 0.086
embryonic heart tube development GO:0035050 65 0.086
negative regulation of molecular function GO:0044092 258 0.085
t cell differentiation GO:0030217 174 0.084
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.084
single organismal cell cell adhesion GO:0016337 131 0.084
metencephalon development GO:0022037 89 0.084
mesodermal cell differentiation GO:0048333 22 0.083
mapk cascade GO:0000165 281 0.083
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.082
action potential GO:0001508 78 0.082
regulation of vesicle mediated transport GO:0060627 139 0.082
prostate gland epithelium morphogenesis GO:0060740 31 0.081
regulation of intracellular transport GO:0032386 159 0.081
negative regulation of cellular protein metabolic process GO:0032269 247 0.081
Human
cardiac epithelial to mesenchymal transition GO:0060317 18 0.081
embryonic skeletal system morphogenesis GO:0048704 91 0.081
organelle localization GO:0051640 179 0.080
regulation of kinase activity GO:0043549 249 0.080
rhythmic process GO:0048511 174 0.080
glycerolipid biosynthetic process GO:0045017 50 0.079
cellular metal ion homeostasis GO:0006875 151 0.078
protein catabolic process GO:0030163 221 0.078
somatotropin secreting cell differentiation GO:0060126 4 0.077
cardiac muscle tissue development GO:0048738 130 0.076
regulation of protein localization GO:0032880 231 0.075
epithelial tube formation GO:0072175 130 0.075
regulation of ion transport GO:0043269 215 0.075
negative regulation of cellular component organization GO:0051129 194 0.075
hypophysis morphogenesis GO:0048850 3 0.074
macromolecule catabolic process GO:0009057 281 0.074
cytokine production GO:0001816 319 0.074
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.074
regulation of lymphocyte activation GO:0051249 240 0.074
mesoderm formation GO:0001707 62 0.073
regulation of secretion by cell GO:1903530 249 0.073
multicellular organismal homeostasis GO:0048871 164 0.073
hair cycle GO:0042633 90 0.073
cytokine mediated signaling pathway GO:0019221 115 0.073
calcium mediated signaling GO:0019722 46 0.073
sensory system development GO:0048880 3 0.072
negative regulation of prostatic bud formation GO:0060686 4 0.072
negative regulation of cellular amine metabolic process GO:0033239 1 0.072
artery development GO:0060840 53 0.071
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.070
regulation of anatomical structure size GO:0090066 178 0.070
cell type specific apoptotic process GO:0097285 268 0.070
paraxial mesodermal cell fate commitment GO:0048343 2 0.070
positive regulation of leukocyte proliferation GO:0070665 73 0.070
lung morphogenesis GO:0060425 50 0.070
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.070
negative regulation of myeloid cell differentiation GO:0045638 38 0.070
regulation of hydrolase activity GO:0051336 246 0.070
renal tubule morphogenesis GO:0061333 72 0.069
regulation of bmp signaling pathway GO:0030510 60 0.069
negative regulation of inflammatory response GO:0050728 61 0.069
cell fate specification GO:0001708 72 0.069
prostate gland development GO:0030850 48 0.069
cartilage morphogenesis GO:0060536 11 0.068
positive regulation of cell death GO:0010942 224 0.068
myelination GO:0042552 74 0.068
sequestering of calcium ion GO:0051208 18 0.068
cerebellum morphogenesis GO:0021587 42 0.068
protein modification by small protein conjugation GO:0032446 187 0.067
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.067
cell substrate adhesion GO:0031589 130 0.066
acetylcholine transport GO:0015870 2 0.065
negative regulation of synapse assembly GO:0051964 3 0.065
intracellular protein transport GO:0006886 204 0.065
astrocyte fate commitment GO:0060018 4 0.065
lung epithelium development GO:0060428 37 0.064
multicellular organismal signaling GO:0035637 91 0.064
neural tube development GO:0021915 160 0.064
regulation of chemotaxis GO:0050920 53 0.064
Mouse
determination of left right symmetry GO:0007368 80 0.064
Mouse
lipid localization GO:0010876 126 0.064
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.063
cell growth GO:0016049 130 0.063
anion transport GO:0006820 177 0.063
regulation of cell projection organization GO:0031344 206 0.062
divalent inorganic cation transport GO:0072511 178 0.062
negative regulation of fat cell differentiation GO:0045599 36 0.062
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.062
regulation of ion homeostasis GO:2000021 64 0.062
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.062
t cell differentiation in thymus GO:0033077 77 0.061
lateral line system development GO:0048925 1 0.061
positive regulation of cell motility GO:2000147 116 0.061
male gonad development GO:0008584 88 0.061
negative regulation of immune system process GO:0002683 209 0.061
Mouse
regulation of cell size GO:0008361 72 0.060
regulation of vasculature development GO:1901342 88 0.060
dendrite development GO:0016358 115 0.059
regulation of monocyte extravasation GO:2000437 2 0.059
positive regulation of epithelial cell proliferation GO:0050679 68 0.059
positive regulation of angiogenesis GO:0045766 46 0.059
positive regulation of cell migration GO:0030335 109 0.059
prostate gland morphogenesis GO:0060512 32 0.059
paraxial mesodermal cell differentiation GO:0048342 2 0.058
endomembrane system organization GO:0010256 147 0.058
multi multicellular organism process GO:0044706 109 0.058
spermatogenesis GO:0007283 284 0.058
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.058
muscle tissue development GO:0060537 308 0.058
cellular lipid metabolic process GO:0044255 323 0.057
skin morphogenesis GO:0043589 38 0.057
cardiac atrium development GO:0003230 24 0.057
Mouse
cardiac right atrium morphogenesis GO:0003213 3 0.057
glandular epithelial cell differentiation GO:0002067 38 0.057
regulation of cardiac muscle tissue development GO:0055024 31 0.057
pancreas development GO:0031016 57 0.056
exocytosis GO:0006887 121 0.056
cellular response to lipid GO:0071396 145 0.056
forebrain generation of neurons GO:0021872 63 0.056
lung epithelial cell differentiation GO:0060487 29 0.056
organic hydroxy compound metabolic process GO:1901615 203 0.055
cellular calcium ion homeostasis GO:0006874 119 0.055
trabecula morphogenesis GO:0061383 40 0.055
Human
embryonic genitalia morphogenesis GO:0030538 4 0.055
positive regulation of cell adhesion GO:0045785 80 0.055
bone mineralization GO:0030282 54 0.055
Human
cell division GO:0051301 120 0.054
peptidyl serine modification GO:0018209 83 0.054
neural tube formation GO:0001841 108 0.054
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.054
ventricular septum development GO:0003281 42 0.054
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.054
cell chemotaxis GO:0060326 81 0.053
Mouse
regulation of cartilage development GO:0061035 44 0.053
synapse assembly GO:0007416 56 0.053
regulation of cell activation GO:0050865 289 0.053
regulation of cellular component size GO:0032535 121 0.052
regulation of tissue remodeling GO:0034103 38 0.052
Human
smooth muscle contraction GO:0006939 44 0.051
response to nutrient levels GO:0031667 109 0.051
regulation of blood circulation GO:1903522 93 0.051
positive regulation of kinase activity GO:0033674 155 0.051
polarity specification of proximal distal axis GO:0010085 2 0.051
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.051
microglial cell activation GO:0001774 3 0.051
second messenger mediated signaling GO:0019932 73 0.051
paramesonephric duct development GO:0061205 3 0.051
muscle contraction GO:0006936 101 0.050
membrane organization GO:0061024 245 0.050
protein localization to nucleus GO:0034504 121 0.050
response to oxygen levels GO:0070482 62 0.050
response to oxidative stress GO:0006979 123 0.050
response to decreased oxygen levels GO:0036293 59 0.049
glycerolipid metabolic process GO:0046486 122 0.049
glycerophospholipid metabolic process GO:0006650 71 0.049
regulation of blood vessel size GO:0050880 56 0.049
cardiac muscle cell proliferation GO:0060038 31 0.049
regulation of angiogenesis GO:0045765 81 0.049
b cell activation GO:0042113 161 0.048
negative regulation of nervous system development GO:0051961 156 0.048
morphogenesis of an epithelial sheet GO:0002011 27 0.048
regulation of biomineral tissue development GO:0070167 33 0.048
Human
muscle cell differentiation GO:0042692 261 0.048
anatomical structure maturation GO:0071695 49 0.048
Human
female gonad development GO:0008585 71 0.048
cellular response to acid chemical GO:0071229 68 0.047
histone modification GO:0016570 159 0.047
ventricular cardiac muscle tissue development GO:0003229 38 0.047
innate immune response GO:0045087 157 0.047
epithelial cell morphogenesis GO:0003382 41 0.047
synapse organization GO:0050808 125 0.047
posttranscriptional regulation of gene expression GO:0010608 155 0.047
sa node cell action potential GO:0086015 4 0.047
regulation of extent of cell growth GO:0061387 52 0.046
regulation of membrane potential GO:0042391 192 0.046
cation homeostasis GO:0055080 212 0.046
sensory perception of sound GO:0007605 97 0.046
embryonic placenta development GO:0001892 98 0.046
transdifferentiation GO:0060290 1 0.046
cerebellar granule cell precursor proliferation GO:0021930 10 0.046
central nervous system morphogenesis GO:0021551 2 0.046
morphogenesis of embryonic epithelium GO:0016331 159 0.045
cell proliferation in hindbrain GO:0021534 10 0.045
respiratory tube development GO:0030323 167 0.045
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.045
regulation of tube size GO:0035150 57 0.044
lung induction GO:0060492 3 0.044
regulation of lipid metabolic process GO:0019216 118 0.044
response to transforming growth factor beta GO:0071559 88 0.044
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.044
cytoplasmic transport GO:0016482 234 0.044
organ induction GO:0001759 21 0.044
regulation of cell adhesion GO:0030155 154 0.043
response to organic cyclic compound GO:0014070 198 0.043
aminoglycan metabolic process GO:0006022 34 0.043
outflow tract morphogenesis GO:0003151 53 0.043
inner cell mass cell proliferation GO:0001833 15 0.043
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.043
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.043
response to hypoxia GO:0001666 58 0.043
regulation of leukocyte differentiation GO:1902105 159 0.042
regulation of muscle system process GO:0090257 80 0.042
covalent chromatin modification GO:0016569 163 0.042
negative regulation of defense response GO:0031348 77 0.042
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.042
embryonic heart tube formation GO:0003144 1 0.042
regulation of glial cell differentiation GO:0045685 41 0.042
regulation of protein kinase activity GO:0045859 232 0.042
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.042
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.042
alcohol biosynthetic process GO:0046165 43 0.042
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.042
protein import into nucleus GO:0006606 95 0.042
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.041
epithelial to mesenchymal transition GO:0001837 47 0.041
Human
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.041
establishment of neuroblast polarity GO:0045200 1 0.041
positive regulation of ion transport GO:0043270 65 0.041
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.041
metanephric nephron tubule development GO:0072234 16 0.041
mesodermal cell fate commitment GO:0001710 17 0.041
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.041
calcium ion homeostasis GO:0055074 127 0.041
regulation of bone mineralization GO:0030500 31 0.041
Human
bone trabecula formation GO:0060346 9 0.041
Human
protein localization to organelle GO:0033365 185 0.041
nuclear import GO:0051170 95 0.040
spleen development GO:0048536 39 0.040
metanephros morphogenesis GO:0003338 24 0.040
central nervous system vasculogenesis GO:0022009 3 0.040
regulation of interleukin 8 secretion GO:2000482 2 0.040
positive regulation of mapk cascade GO:0043410 170 0.040
pancreatic pp cell fate commitment GO:0003329 2 0.040
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.039
response to amino acid GO:0043200 37 0.039
somatic stem cell maintenance GO:0035019 47 0.039
cerebellar cortex formation GO:0021697 22 0.039
positive regulation of cartilage development GO:0061036 18 0.039
positive regulation of cytokine production GO:0001819 174 0.039
positive regulation of transferase activity GO:0051347 167 0.039
germ cell development GO:0007281 185 0.039
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.039
mesenchymal cell development GO:0014031 93 0.039
Human
regulation of cytoskeleton organization GO:0051493 122 0.038
developmental induction GO:0031128 34 0.038
hormone secretion GO:0046879 128 0.038
anatomical structure homeostasis GO:0060249 145 0.038
cardiac septum morphogenesis GO:0060411 46 0.038
embryonic heart tube morphogenesis GO:0003143 51 0.038
regulation of proteolysis GO:0030162 164 0.037
forebrain neuron development GO:0021884 30 0.037
lipid transport GO:0006869 98 0.037
positive regulation of homeostatic process GO:0032846 64 0.037
regulation of cell cycle GO:0051726 281 0.037
mesenchyme development GO:0060485 152 0.037
Human Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.037
developmental cell growth GO:0048588 84 0.037
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.037
placenta development GO:0001890 140 0.037
vascular process in circulatory system GO:0003018 62 0.037
olfactory bulb interneuron differentiation GO:0021889 12 0.037
mammary gland duct morphogenesis GO:0060603 38 0.037
negative regulation of secretion by cell GO:1903531 54 0.036
regulation of organelle organization GO:0033043 289 0.036
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.036
insulin secretion GO:0030073 89 0.036
negative regulation of cell activation GO:0050866 111 0.036
mesonephric duct morphogenesis GO:0072180 4 0.036

Grem1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.217
musculoskeletal system disease DOID:17 0 0.217
connective tissue disease DOID:65 0 0.059
bone disease DOID:0080001 0 0.044
nervous system disease DOID:863 0 0.043