Mus musculus

93 known processes

Itpr1

inositol 1,4,5-trisphosphate receptor 1

(Aliases: P400,Ip3r,opt,Pcp1,Itpr-1,D6Pas2,Pcp-1,IP3R1,InsP3R)

Itpr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rhodopsin mediated signaling pathway GO:0016056 4 0.354
macromolecule catabolic process GO:0009057 281 0.301
Worm
regulation of membrane potential GO:0042391 192 0.238
Fly
calcium ion transmembrane transport GO:0070588 85 0.219
cellular chemical homeostasis GO:0055082 215 0.198
regulation of ion transmembrane transporter activity GO:0032412 54 0.188
nucleotide metabolic process GO:0009117 332 0.175
cellular homeostasis GO:0019725 240 0.174
g protein coupled receptor signaling pathway GO:0007186 243 0.172
Fly
regulation of ion transmembrane transport GO:0034765 119 0.171
cognition GO:0050890 149 0.166
Mouse
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity GO:0031585 2 0.153
cation homeostasis GO:0055080 212 0.153
cellular ion homeostasis GO:0006873 165 0.148
regulation of hydrolase activity GO:0051336 246 0.138
nucleoside phosphate metabolic process GO:0006753 338 0.138
leukocyte differentiation GO:0002521 342 0.136
calcium ion transport GO:0006816 159 0.130
nucleoside catabolic process GO:0009164 206 0.124
muscle tissue development GO:0060537 308 0.123
purine nucleotide metabolic process GO:0006163 302 0.123
response to radiation GO:0009314 165 0.122
multicellular organismal signaling GO:0035637 91 0.117
divalent inorganic cation transport GO:0072511 178 0.113
ribose phosphate metabolic process GO:0019693 291 0.111
regulation of transmembrane transport GO:0034762 128 0.111
regulation of transporter activity GO:0032409 57 0.109
organonitrogen compound catabolic process GO:1901565 264 0.108
response to light stimulus GO:0009416 135 0.108
regulation of ion transport GO:0043269 215 0.107
mitotic cell cycle process GO:1903047 159 0.107
cellular divalent inorganic cation homeostasis GO:0072503 127 0.106
striated muscle tissue development GO:0014706 293 0.106
fertilization GO:0009566 127 0.103
cation transport GO:0006812 399 0.102
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.097
myotube differentiation GO:0014902 105 0.097
muscle cell differentiation GO:0042692 261 0.097
forebrain development GO:0030900 302 0.097
locomotory behavior GO:0007626 195 0.095
Worm Fly
regulation of homeostatic process GO:0032844 182 0.095
regulation of cation channel activity GO:2001257 22 0.092
ribonucleoside metabolic process GO:0009119 245 0.089
metal ion homeostasis GO:0055065 189 0.088
calcium ion homeostasis GO:0055074 127 0.088
inorganic ion transmembrane transport GO:0098660 234 0.087
nucleoside triphosphate catabolic process GO:0009143 205 0.087
cellular metal ion homeostasis GO:0006875 151 0.085
cation transmembrane transport GO:0098655 266 0.085
cellular ketone metabolic process GO:0042180 84 0.084
glycoprotein metabolic process GO:0009100 116 0.084
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.084
purine containing compound metabolic process GO:0072521 311 0.083
adult locomotory behavior GO:0008344 91 0.082
Fly
carbohydrate derivative biosynthetic process GO:1901137 183 0.082
divalent inorganic cation homeostasis GO:0072507 138 0.082
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.081
nucleobase containing small molecule metabolic process GO:0055086 352 0.081
acetylcholine secretion neurotransmission GO:0014055 2 0.080
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.080
regulation of cellular amino acid metabolic process GO:0006521 5 0.080
purine nucleotide catabolic process GO:0006195 211 0.079
organophosphate biosynthetic process GO:0090407 122 0.078
telencephalon development GO:0021537 186 0.078
ion transmembrane transport GO:0034220 361 0.076
multi organism behavior GO:0051705 62 0.076
Worm
regulation of organelle organization GO:0033043 289 0.075
sequestering of metal ion GO:0051238 19 0.074
purine nucleoside metabolic process GO:0042278 241 0.074
purine nucleoside catabolic process GO:0006152 205 0.072
nuclear division GO:0000280 158 0.072
Fly
blood vessel morphogenesis GO:0048514 285 0.071
positive regulation of apoptotic process GO:0043065 217 0.071
nucleoside triphosphate metabolic process GO:0009141 230 0.071
muscle cell development GO:0055001 133 0.070
circadian rhythm GO:0007623 114 0.068
heterocycle catabolic process GO:0046700 280 0.068
amine metabolic process GO:0009308 45 0.066
cell cycle g1 s phase transition GO:0044843 57 0.066
learning or memory GO:0007611 148 0.066
Mouse
transmembrane transport GO:0055085 412 0.065
reproductive behavior GO:0019098 32 0.065
Worm
transmission of nerve impulse GO:0019226 76 0.064
small gtpase mediated signal transduction GO:0007264 97 0.064
glycosyl compound catabolic process GO:1901658 206 0.064
sensory perception GO:0007600 245 0.064
Mouse Fly
neuron death GO:0070997 154 0.063
ribonucleotide metabolic process GO:0009259 291 0.063
purine containing compound catabolic process GO:0072523 213 0.062
apoptotic signaling pathway GO:0097190 306 0.062
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.062
purine ribonucleoside metabolic process GO:0046128 241 0.062
single fertilization GO:0007338 82 0.062
axon ensheathment GO:0008366 76 0.061
negative regulation of homeostatic process GO:0032845 71 0.061
ubiquitin dependent protein catabolic process GO:0006511 129 0.061
nucleoside metabolic process GO:0009116 246 0.061
cellular nitrogen compound catabolic process GO:0044270 280 0.060
cytoplasmic transport GO:0016482 234 0.060
cellular calcium ion homeostasis GO:0006874 119 0.059
ribonucleoside triphosphate metabolic process GO:0009199 220 0.059
multi multicellular organism process GO:0044706 109 0.058
Worm
regulation of calcium ion transmembrane transport GO:1903169 20 0.058
purine ribonucleoside catabolic process GO:0046130 205 0.058
divalent metal ion transport GO:0070838 172 0.057
regulation of cellular ketone metabolic process GO:0010565 66 0.057
multicellular organismal reproductive behavior GO:0033057 23 0.057
Worm
purine nucleoside triphosphate metabolic process GO:0009144 226 0.056
phospholipid metabolic process GO:0006644 87 0.056
regulation of cellular amine metabolic process GO:0033238 20 0.055
meiotic nuclear division GO:0007126 115 0.055
mitochondrion organization GO:0007005 134 0.055
ribonucleoside catabolic process GO:0042454 206 0.054
cellular response to growth factor stimulus GO:0071363 197 0.054
intracellular protein transport GO:0006886 204 0.054
cellular response to abiotic stimulus GO:0071214 56 0.053
positive regulation of growth GO:0045927 104 0.053
cytokine production GO:0001816 319 0.053
purine nucleoside triphosphate catabolic process GO:0009146 203 0.053
protein ubiquitination GO:0016567 171 0.052
modification dependent macromolecule catabolic process GO:0043632 133 0.052
nitrogen compound transport GO:0071705 271 0.052
neurotransmitter secretion GO:0007269 62 0.051
regulation of cell motility GO:2000145 236 0.051
Worm
nucleoside phosphate catabolic process GO:1901292 222 0.051
positive regulation of ion transmembrane transport GO:0034767 24 0.051
chemotaxis GO:0006935 247 0.051
olfactory learning GO:0008355 2 0.051
nucleotide catabolic process GO:0009166 217 0.051
cellular amino acid metabolic process GO:0006520 103 0.051
positive regulation of calcium ion transport GO:0051928 27 0.051
leukocyte migration GO:0050900 124 0.050
purine ribonucleotide metabolic process GO:0009150 290 0.050
regulation of calcium ion transport GO:0051924 69 0.049
negative regulation of protein metabolic process GO:0051248 282 0.049
dephosphorylation GO:0016311 129 0.049
organic hydroxy compound biosynthetic process GO:1901617 77 0.049
glycoprotein biosynthetic process GO:0009101 89 0.049
adult behavior GO:0030534 135 0.049
Fly
acetylcholine transport GO:0015870 2 0.048
phototransduction GO:0007602 17 0.048
response to transforming growth factor beta GO:0071559 88 0.047
calcium mediated signaling GO:0019722 46 0.047
Human
skeletal muscle organ development GO:0060538 163 0.047
synaptic transmission GO:0007268 329 0.046
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.046
positive regulation of ion transport GO:0043270 65 0.046
mitotic cell cycle GO:0000278 195 0.046
protein catabolic process GO:0030163 221 0.046
Worm
modification dependent protein catabolic process GO:0019941 133 0.045
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.045
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.045
organophosphate catabolic process GO:0046434 232 0.044
small molecule biosynthetic process GO:0044283 132 0.044
regulation of secretion GO:0051046 274 0.044
neuronal action potential GO:0019228 54 0.044
regulation of metal ion transport GO:0010959 106 0.044
dopamine receptor signaling pathway GO:0007212 16 0.044
regulation of nucleotide metabolic process GO:0006140 169 0.044
response to growth factor GO:0070848 198 0.044
central nervous system neuron differentiation GO:0021953 162 0.044
regulation of vesicle mediated transport GO:0060627 139 0.044
ribonucleotide catabolic process GO:0009261 208 0.044
regulation of ion homeostasis GO:2000021 64 0.043
regulation of cell projection organization GO:0031344 206 0.043
Worm
glycosyl compound metabolic process GO:1901657 246 0.043
positive regulation of programmed cell death GO:0043068 218 0.043
cellular response to radiation GO:0071478 28 0.043
rhythmic process GO:0048511 174 0.043
Worm
anatomical structure homeostasis GO:0060249 145 0.043
positive regulation of transmembrane transport GO:0034764 29 0.043
proteasomal protein catabolic process GO:0010498 98 0.043
regulation of circadian rhythm GO:0042752 58 0.043
cell type specific apoptotic process GO:0097285 268 0.043
ribonucleoside triphosphate catabolic process GO:0009203 199 0.043
positive regulation of calcium ion transmembrane transporter activity GO:1901021 8 0.042
dna metabolic process GO:0006259 303 0.042
regulation of neurotransmitter transport GO:0051588 35 0.042
regulation of feeding behavior GO:0060259 3 0.042
Worm Fly
regulation of neuron projection development GO:0010975 169 0.042
response to endoplasmic reticulum stress GO:0034976 53 0.042
g1 s transition of mitotic cell cycle GO:0000082 57 0.041
regulation of multi organism process GO:0043900 111 0.041
cellular response to light stimulus GO:0071482 19 0.041
regulation of cell migration GO:0030334 219 0.041
Worm
developmental maturation GO:0021700 193 0.041
Worm
feeding behavior GO:0007631 62 0.041
Worm Fly
response to inorganic substance GO:0010035 96 0.041
neuron apoptotic process GO:0051402 142 0.041
lymphocyte differentiation GO:0030098 242 0.041
positive regulation of hydrolase activity GO:0051345 148 0.041
carbohydrate metabolic process GO:0005975 230 0.040
calcium ion dependent exocytosis GO:0017156 35 0.040
multicellular organism growth GO:0035264 161 0.040
cytosolic calcium ion homeostasis GO:0051480 70 0.040
cellular macromolecule catabolic process GO:0044265 206 0.040
cellular protein catabolic process GO:0044257 155 0.038
spermatogenesis GO:0007283 284 0.038
microtubule based movement GO:0007018 84 0.038
regulation of neuron apoptotic process GO:0043523 122 0.038
peptidyl amino acid modification GO:0018193 336 0.038
axonogenesis GO:0007409 274 0.038
cellular amine metabolic process GO:0044106 44 0.037
phototransduction visible light GO:0007603 6 0.037
regionalization GO:0003002 337 0.037
striated muscle cell development GO:0055002 125 0.036
regulation of circadian sleep wake cycle GO:0042749 3 0.036
organelle assembly GO:0070925 177 0.036
cellular lipid metabolic process GO:0044255 323 0.036
memory GO:0007613 58 0.035
Mouse
detection of external stimulus GO:0009581 61 0.035
organonitrogen compound biosynthetic process GO:1901566 192 0.035
detection of chemical stimulus involved in sensory perception GO:0050907 10 0.034
inorganic cation transmembrane transport GO:0098662 207 0.034
regulation of cell cycle GO:0051726 281 0.034
wnt signaling pathway GO:0016055 188 0.034
exocytosis GO:0006887 121 0.034
glutamate receptor signaling pathway GO:0007215 35 0.034
ensheathment of neurons GO:0007272 76 0.034
skeletal muscle fiber development GO:0048741 58 0.034
cell recognition GO:0008037 83 0.034
detection of abiotic stimulus GO:0009582 60 0.034
positive regulation of nucleotide metabolic process GO:0045981 114 0.033
microtubule based process GO:0007017 236 0.033
b cell activation GO:0042113 161 0.033
action potential GO:0001508 78 0.033
glial cell differentiation GO:0010001 131 0.033
regulation of nucleotide catabolic process GO:0030811 122 0.032
gliogenesis GO:0042063 141 0.032
regulation of protein localization GO:0032880 231 0.032
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.032
regulation of purine nucleotide metabolic process GO:1900542 169 0.032
regulation of neurotransmitter levels GO:0001505 87 0.032
neural tube development GO:0021915 160 0.032
second messenger mediated signaling GO:0019932 73 0.032
b cell differentiation GO:0030183 78 0.031
organic hydroxy compound metabolic process GO:1901615 203 0.031
detection of visible light GO:0009584 14 0.031
ras protein signal transduction GO:0007265 77 0.030
negative regulation of cellular component organization GO:0051129 194 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.030
maintenance of location GO:0051235 89 0.030
cerebellum development GO:0021549 77 0.030
organic cyclic compound catabolic process GO:1901361 295 0.030
regulation of neuron death GO:1901214 134 0.030
positive regulation of cell death GO:0010942 224 0.030
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.030
polyol metabolic process GO:0019751 26 0.030
regulation of secretion by cell GO:1903530 249 0.030
organelle fission GO:0048285 170 0.030
Fly
male gamete generation GO:0048232 285 0.029
endomembrane system organization GO:0010256 147 0.029
positive regulation of organelle organization GO:0010638 128 0.029
multi organism reproductive behavior GO:0044705 29 0.029
Worm
purine ribonucleotide catabolic process GO:0009154 208 0.028
glycerolipid metabolic process GO:0046486 122 0.028
nucleoside monophosphate metabolic process GO:0009123 85 0.028
ribonucleoside monophosphate metabolic process GO:0009161 80 0.028
myelination GO:0042552 74 0.028
placenta development GO:0001890 140 0.028
negative regulation of molecular function GO:0044092 258 0.028
rho protein signal transduction GO:0007266 32 0.028
associative learning GO:0008306 61 0.028
immune response regulating signaling pathway GO:0002764 125 0.028
actin filament based movement GO:0030048 23 0.027
regulation of nucleoside metabolic process GO:0009118 130 0.027
positive regulation of nervous system development GO:0051962 221 0.027
microtubule cytoskeleton organization GO:0000226 157 0.027
meiotic cell cycle GO:0051321 122 0.027
muscle fiber development GO:0048747 76 0.027
regulation of gtp catabolic process GO:0033124 113 0.027
regulation of cellular catabolic process GO:0031329 242 0.027
regulation of kinase activity GO:0043549 249 0.027
multicellular organismal homeostasis GO:0048871 164 0.027
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.027
pallium development GO:0021543 120 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.027
protein targeting GO:0006605 143 0.026
smoothened signaling pathway GO:0007224 105 0.026
skeletal system development GO:0001501 356 0.026
aromatic compound catabolic process GO:0019439 286 0.026
synapse organization GO:0050808 125 0.026
alcohol metabolic process GO:0006066 116 0.026
muscle contraction GO:0006936 101 0.026
Worm
response to oxidative stress GO:0006979 123 0.026
Fly
tissue homeostasis GO:0001894 115 0.025
response to organonitrogen compound GO:0010243 246 0.025
Mouse
protein modification by small protein conjugation GO:0032446 187 0.025
negative regulation of phosphate metabolic process GO:0045936 184 0.025
embryonic organ morphogenesis GO:0048562 276 0.025
intrinsic apoptotic signaling pathway GO:0097193 132 0.025
establishment of organelle localization GO:0051656 122 0.025
neurotransmitter transport GO:0006836 76 0.025
negative regulation of cell development GO:0010721 169 0.025
adaptive immune response GO:0002250 155 0.025
monocarboxylic acid metabolic process GO:0032787 191 0.025
sensory perception of taste GO:0050909 18 0.025
Mouse Fly
regulation of neurotransmitter secretion GO:0046928 29 0.025
heart morphogenesis GO:0003007 178 0.024
regulation of system process GO:0044057 200 0.024
regulation of cell activation GO:0050865 289 0.024
negative regulation of nervous system development GO:0051961 156 0.024
germ cell development GO:0007281 185 0.024
Worm
regulation of neuron differentiation GO:0045664 281 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.024
gland development GO:0048732 330 0.024
peptidyl serine modification GO:0018209 83 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.024
regulation of cell cycle g1 s phase transition GO:1902806 35 0.023
response to molecule of bacterial origin GO:0002237 143 0.023
positive regulation of ras gtpase activity GO:0032320 65 0.023
glucose homeostasis GO:0042593 128 0.023
activation of immune response GO:0002253 138 0.023
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.023
regulation of synaptic plasticity GO:0048167 87 0.023
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.023
Worm
regulation of protein kinase activity GO:0045859 232 0.023
neural tube formation GO:0001841 108 0.023
cellular component assembly involved in morphogenesis GO:0010927 139 0.023
tube formation GO:0035148 140 0.023
myosin filament assembly GO:0031034 2 0.023
positive regulation of cell development GO:0010720 237 0.023
regulation of striated muscle cell differentiation GO:0051153 81 0.023
regulation of reproductive process GO:2000241 66 0.023
response to uv GO:0009411 44 0.022
alcohol biosynthetic process GO:0046165 43 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
lymphocyte proliferation GO:0046651 164 0.022
spermatid development GO:0007286 108 0.022
regulation of intracellular transport GO:0032386 159 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
plasma membrane organization GO:0007009 90 0.022
acetate ester transport GO:1901374 2 0.022
insemination GO:0007320 6 0.022
Worm
connective tissue development GO:0061448 179 0.022
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.022
response to lipopolysaccharide GO:0032496 128 0.022
myosin filament organization GO:0031033 3 0.022
regulation of cell cycle process GO:0010564 160 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
Human
carbohydrate derivative catabolic process GO:1901136 231 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.021
establishment of mitochondrion localization GO:0051654 4 0.021
release of sequestered calcium ion into cytosol GO:0051209 42 0.021
glycerophospholipid metabolic process GO:0006650 71 0.021
positive regulation of cation channel activity GO:2001259 8 0.021
circulatory system process GO:0003013 197 0.021
camera type eye development GO:0043010 266 0.021
negative regulation of immune system process GO:0002683 209 0.021
cerebellum morphogenesis GO:0021587 42 0.021
cell adhesion GO:0007155 329 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
response to temperature stimulus GO:0009266 55 0.021
axon guidance GO:0007411 141 0.020
b 1 b cell differentiation GO:0001923 3 0.020
cofactor metabolic process GO:0051186 80 0.020
positive regulation of muscle cell differentiation GO:0051149 39 0.020
cell maturation GO:0048469 127 0.020
Worm
epithelial tube morphogenesis GO:0060562 303 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
regulation of exocytosis GO:0017157 61 0.020
striated muscle myosin thick filament assembly GO:0071688 1 0.020
positive regulation of nucleoside metabolic process GO:0045979 91 0.020
immune response activating signal transduction GO:0002757 116 0.020
sensory perception of smell GO:0007608 26 0.020
cell growth GO:0016049 130 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
primary neural tube formation GO:0014020 95 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
mating GO:0007618 27 0.020
Worm
protein localization to organelle GO:0033365 185 0.020
mitochondrion distribution GO:0048311 4 0.020
regulation of cytokine production GO:0001817 266 0.019
learning GO:0007612 98 0.019
gtp metabolic process GO:0046039 144 0.019
myotube cell development GO:0014904 60 0.019
regulation of cytoskeleton organization GO:0051493 122 0.019
positive regulation of transporter activity GO:0032411 17 0.019
mitotic cytokinesis GO:0000281 4 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.019
dendrite development GO:0016358 115 0.019
regulation of transferase activity GO:0051338 263 0.019
angiogenesis GO:0001525 201 0.019
anion transport GO:0006820 177 0.019
immune effector process GO:0002252 321 0.019
regulation of monocyte extravasation GO:2000437 2 0.019
regulation of binding GO:0051098 111 0.019
positive regulation of gtp catabolic process GO:0033126 85 0.019
membrane depolarization GO:0051899 64 0.019
protein maturation GO:0051604 176 0.019
limbic system development GO:0021761 72 0.018
engulfment of apoptotic cell GO:0043652 3 0.018
lipid localization GO:0010876 126 0.018
positive regulation of protein modification process GO:0031401 299 0.018
respiratory system development GO:0060541 190 0.018
gtp catabolic process GO:0006184 143 0.018
lipid biosynthetic process GO:0008610 179 0.018
vesicle transport along microtubule GO:0047496 9 0.018
monocyte extravasation GO:0035696 2 0.018
response to metal ion GO:0010038 47 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
cardiac muscle tissue development GO:0048738 130 0.018
organic acid biosynthetic process GO:0016053 86 0.018
atp catabolic process GO:0006200 55 0.018
positive regulation of secretion GO:0051047 130 0.018
phosphatidylinositol metabolic process GO:0046488 45 0.018
carboxylic acid transport GO:0046942 100 0.018
protein localization to membrane GO:0072657 108 0.018
detection of light stimulus GO:0009583 25 0.018
cerebral cortex development GO:0021987 86 0.018
organic anion transport GO:0015711 137 0.018
regulation of proteolysis GO:0030162 164 0.018
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.018
carboxylic acid biosynthetic process GO:0046394 86 0.018
golgi vesicle transport GO:0048193 30 0.018
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.018
regulation of lymphocyte activation GO:0051249 240 0.017
establishment of protein localization to organelle GO:0072594 118 0.017
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
regulation of protein binding GO:0043393 60 0.017
regulation of nuclear division GO:0051783 56 0.017
regulation of defense response GO:0031347 233 0.017
production of molecular mediator of immune response GO:0002440 103 0.017
chromatin modification GO:0016568 187 0.017
negative regulation of protein modification process GO:0031400 163 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
detection of stimulus GO:0051606 84 0.017
microtubule based transport GO:0010970 50 0.017
protein glycosylation GO:0006486 55 0.017
blastocyst development GO:0001824 80 0.017
myeloid leukocyte differentiation GO:0002573 119 0.017
positive regulation of amine transport GO:0051954 8 0.017
striated muscle contraction GO:0006941 45 0.017
oocyte axis specification GO:0007309 2 0.017
meiotic cell cycle process GO:1903046 77 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
embryonic placenta development GO:0001892 98 0.016
leukocyte proliferation GO:0070661 172 0.016
macromolecule glycosylation GO:0043413 55 0.016
negative regulation of neuron death GO:1901215 98 0.016
cell activation involved in immune response GO:0002263 126 0.016
photoreceptor cell maintenance GO:0045494 19 0.016
sensory perception of chemical stimulus GO:0007606 51 0.016
Mouse Fly
positive regulation of rho gtpase activity GO:0032321 41 0.016
regulation of mitotic cell cycle phase transition GO:1901990 73 0.016
organic acid transport GO:0015849 101 0.016
actin cytoskeleton organization GO:0030036 220 0.016
spermatid differentiation GO:0048515 115 0.016
cerebellar cortex development GO:0021695 48 0.016
ribonucleoside monophosphate catabolic process GO:0009158 57 0.016
covalent chromatin modification GO:0016569 163 0.016
metencephalon development GO:0022037 89 0.016
sequestering of calcium ion GO:0051208 18 0.016
positive regulation of kinase activity GO:0033674 155 0.016
midgut development GO:0007494 4 0.016
positive regulation of cytokine production GO:0001819 174 0.016
positive regulation of cell cycle process GO:0090068 61 0.016
positive regulation of nucleotide catabolic process GO:0030813 88 0.016
regulation of muscle system process GO:0090257 80 0.016
response to organic cyclic compound GO:0014070 198 0.016
Mouse
fat cell differentiation GO:0045444 160 0.015
response to nutrient levels GO:0031667 109 0.015
Fly
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
syncytium formation by plasma membrane fusion GO:0000768 42 0.015
cell division GO:0051301 120 0.015
carbohydrate biosynthetic process GO:0016051 74 0.015
positive regulation of gtpase activity GO:0043547 85 0.015
regulation of rho gtpase activity GO:0032319 58 0.015
histone modification GO:0016570 159 0.015
retina homeostasis GO:0001895 23 0.015
regulation of myotube differentiation GO:0010830 62 0.015
regulation of cell cycle phase transition GO:1901987 77 0.015
development of primary sexual characteristics GO:0045137 143 0.015
regulation of actin cytoskeleton organization GO:0032956 84 0.015
activation of meiosis GO:0090427 4 0.015
nucleoside phosphate biosynthetic process GO:1901293 79 0.015
purine nucleoside monophosphate catabolic process GO:0009128 58 0.015
neuron neuron synaptic transmission GO:0007270 69 0.015
protein processing GO:0016485 163 0.015
negative regulation of neuron apoptotic process GO:0043524 92 0.015
regulation of receptor activity GO:0010469 41 0.015
gonad development GO:0008406 141 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
small molecule catabolic process GO:0044282 71 0.015
sensory perception of sound GO:0007605 97 0.015
lymphocyte mediated immunity GO:0002449 139 0.015

Itpr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.124
Human
disease of anatomical entity DOID:7 0 0.124
Human
nervous system disease DOID:863 0 0.124
Human
brain disease DOID:936 0 0.021
sensory system disease DOID:0050155 0 0.015