Mus musculus

56 known processes

Rpgr

retinitis pigmentosa GTPase regulator

(Aliases: Rp3h)

Rpgr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium morphogenesis GO:0060271 102 0.834
Human Zebrafish
cilium assembly GO:0042384 81 0.745
Human
organelle assembly GO:0070925 177 0.457
Human
microtubule based movement GO:0007018 84 0.356
cytoskeleton dependent intracellular transport GO:0030705 50 0.303
eye photoreceptor cell differentiation GO:0001754 41 0.204
microtubule cytoskeleton organization GO:0000226 157 0.154
cellular component assembly involved in morphogenesis GO:0010927 139 0.125
Human
organelle localization GO:0051640 179 0.100
microtubule based transport GO:0010970 50 0.093
microtubule based process GO:0007017 236 0.089
regulation of cellular amine metabolic process GO:0033238 20 0.086
hematopoietic progenitor cell differentiation GO:0002244 143 0.067
intraciliary transport GO:0042073 9 0.066
cellular amino acid metabolic process GO:0006520 103 0.064
glycosyl compound metabolic process GO:1901657 246 0.051
retina development in camera type eye GO:0060041 119 0.047
Zebrafish
photoreceptor cell differentiation GO:0046530 52 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.044
digestive tract development GO:0048565 190 0.044
spermatogenesis GO:0007283 284 0.044
protein polymerization GO:0051258 57 0.043
sensory organ morphogenesis GO:0090596 242 0.040
positive regulation of cellular amine metabolic process GO:0033240 5 0.040
dna metabolic process GO:0006259 303 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
male gamete generation GO:0048232 285 0.034
maintenance of location GO:0051235 89 0.034
regulation of cellular component biogenesis GO:0044087 181 0.033
organic cyclic compound catabolic process GO:1901361 295 0.033
organophosphate catabolic process GO:0046434 232 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.033
photoreceptor cell development GO:0042461 40 0.033
determination of left right symmetry GO:0007368 80 0.031
Zebrafish
digestive system development GO:0055123 200 0.031
centrosome organization GO:0051297 26 0.030
nucleoside triphosphate metabolic process GO:0009141 230 0.028
positive regulation of protein modification process GO:0031401 299 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
negative regulation of cell proliferation GO:0008285 296 0.027
ribonucleotide metabolic process GO:0009259 291 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
microtubule polymerization or depolymerization GO:0031109 26 0.026
cellular amine metabolic process GO:0044106 44 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
nucleoside monophosphate catabolic process GO:0009125 59 0.025
regulation of organelle organization GO:0033043 289 0.025
cellularization GO:0007349 1 0.024
amine metabolic process GO:0009308 45 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
digestive tract morphogenesis GO:0048546 147 0.024
appendage development GO:0048736 166 0.024
early endosome to late endosome transport GO:0045022 2 0.024
skin development GO:0043588 220 0.023
heterocycle catabolic process GO:0046700 280 0.023
axoneme assembly GO:0035082 15 0.023
purine containing compound metabolic process GO:0072521 311 0.023
establishment of organelle localization GO:0051656 122 0.023
cytoplasmic transport GO:0016482 234 0.022
establishment or maintenance of cell polarity GO:0007163 86 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
macromolecule catabolic process GO:0009057 281 0.021
regulation of dendritic spine morphogenesis GO:0061001 17 0.021
establishment of mitochondrion localization GO:0051654 4 0.021
microtubule anchoring at microtubule organizing center GO:0072393 5 0.021
cellular response to dna damage stimulus GO:0006974 207 0.021
gastrulation GO:0007369 116 0.020
forebrain development GO:0030900 302 0.020
cation transport GO:0006812 399 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
methylation GO:0032259 134 0.019
regulation of cell cycle GO:0051726 281 0.019
microtubule organizing center organization GO:0031023 28 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
immune effector process GO:0002252 321 0.019
protein localization to organelle GO:0033365 185 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.018
positive regulation of cellular component biogenesis GO:0044089 94 0.018
regulation of cellular ketone metabolic process GO:0010565 66 0.018
sensory perception GO:0007600 245 0.018
positive regulation of organelle organization GO:0010638 128 0.018
regulation of smoothened signaling pathway GO:0008589 58 0.017
positive regulation of dendrite development GO:1900006 21 0.017
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.016
sperm individualization GO:0007291 1 0.016
nucleotide catabolic process GO:0009166 217 0.016
protein catabolic process GO:0030163 221 0.016
cell adhesion GO:0007155 329 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
response to fibroblast growth factor GO:0071774 47 0.016
homeostasis of number of cells GO:0048872 210 0.016
wnt signaling pathway GO:0016055 188 0.016
epithelial cell proliferation GO:0050673 174 0.016
regionalization GO:0003002 337 0.016
embryonic limb morphogenesis GO:0030326 126 0.016
muscle cell differentiation GO:0042692 261 0.016
regulation of cell projection organization GO:0031344 206 0.015
smoothened signaling pathway GO:0007224 105 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
protein maturation GO:0051604 176 0.015
morphogenesis of embryonic epithelium GO:0016331 159 0.015
camera type eye development GO:0043010 266 0.015
Zebrafish
small gtpase mediated signal transduction GO:0007264 97 0.015
olfactory learning GO:0008355 2 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
positive regulation of dendritic spine morphogenesis GO:0061003 8 0.014
dna repair GO:0006281 107 0.014
glucose homeostasis GO:0042593 128 0.014
muscle adaptation GO:0043500 39 0.014
cellular ketone metabolic process GO:0042180 84 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
positive regulation of nervous system development GO:0051962 221 0.014
purine containing compound catabolic process GO:0072523 213 0.013
intracellular protein transport GO:0006886 204 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
neural precursor cell proliferation GO:0061351 121 0.013
epithelial cilium movement GO:0003351 12 0.013
Zebrafish
cell type specific apoptotic process GO:0097285 268 0.013
purine nucleoside monophosphate catabolic process GO:0009128 58 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
aromatic compound catabolic process GO:0019439 286 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
negative regulation of molecular function GO:0044092 258 0.013
exocytosis GO:0006887 121 0.013
viral process GO:0016032 41 0.013
multicellular organism growth GO:0035264 161 0.012
fat cell differentiation GO:0045444 160 0.012
cellular response to lipid GO:0071396 145 0.012
macromolecule methylation GO:0043414 120 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
synapse assembly GO:0007416 56 0.012
cognition GO:0050890 149 0.012
nucleoside catabolic process GO:0009164 206 0.012
transmembrane transport GO:0055085 412 0.012
cellular protein complex assembly GO:0043623 116 0.012
regulation of synapse assembly GO:0051963 29 0.012
protein ubiquitination GO:0016567 171 0.012
embryonic organ morphogenesis GO:0048562 276 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
actin filament organization GO:0007015 113 0.011
cellular homeostasis GO:0019725 240 0.011
nitrogen compound transport GO:0071705 271 0.011
oocyte construction GO:0007308 2 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
ear development GO:0043583 200 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
retina morphogenesis in camera type eye GO:0060042 45 0.011
Zebrafish
leukocyte mediated immunity GO:0002443 174 0.011
regulation of protein catabolic process GO:0042176 108 0.011
epidermis development GO:0008544 187 0.011
myosin filament organization GO:0031033 3 0.011
sensory perception of light stimulus GO:0050953 54 0.011
myosin filament assembly GO:0031034 2 0.011
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
anatomical structure homeostasis GO:0060249 145 0.011
telencephalon development GO:0021537 186 0.011
carbohydrate homeostasis GO:0033500 128 0.011
positive regulation of cell development GO:0010720 237 0.011
rho protein signal transduction GO:0007266 32 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
nucleotide metabolic process GO:0009117 332 0.011
tube formation GO:0035148 140 0.011
protein targeting to vacuole GO:0006623 3 0.011
kidney development GO:0001822 213 0.011
negative regulation of cytoskeleton organization GO:0051494 36 0.011
regulation of hydrolase activity GO:0051336 246 0.011
protein localization to membrane GO:0072657 108 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
protein localization to vacuole GO:0072665 4 0.010
negative regulation of nervous system development GO:0051961 156 0.010
synapse organization GO:0050808 125 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
regulation of cellular catabolic process GO:0031329 242 0.010
regulation of microtubule based process GO:0032886 52 0.010

Rpgr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.071
Human
disease of anatomical entity DOID:7 0 0.071
Human
organ system cancer DOID:0050686 0 0.028
endocrine gland cancer DOID:170 0 0.028
disease of cellular proliferation DOID:14566 0 0.028
cancer DOID:162 0 0.028
central nervous system disease DOID:331 0 0.023
sensory system disease DOID:0050155 0 0.014
Human
eye and adnexa disease DOID:1492 0 0.014
Human
neurodegenerative disease DOID:1289 0 0.011
eye disease DOID:5614 0 0.011
Human