Mus musculus

75 known processes

Spnb2

spectrin beta 2

(Aliases: mKIAA4049,KIAA4049,9930031C03Rik,elf3,AL033301,elf1,Spnb-2,SPTB2,SPTBN1)

Spnb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine nucleotide metabolic process GO:0006163 302 0.963
microtubule cytoskeleton organization GO:0000226 157 0.866
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.834
purine containing compound metabolic process GO:0072521 311 0.833
nucleoside triphosphate catabolic process GO:0009143 205 0.827
homeostasis of number of cells GO:0048872 210 0.824
glycosyl compound catabolic process GO:1901658 206 0.809
ribonucleoside catabolic process GO:0042454 206 0.809
purine ribonucleotide catabolic process GO:0009154 208 0.763
purine ribonucleoside metabolic process GO:0046128 241 0.741
positive regulation of cell death GO:0010942 224 0.740
dendrite development GO:0016358 115 0.730
Worm
microtubule based process GO:0007017 236 0.718
nucleoside phosphate metabolic process GO:0006753 338 0.708
nucleobase containing small molecule metabolic process GO:0055086 352 0.703
cation transport GO:0006812 399 0.687
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.679
organic cyclic compound catabolic process GO:1901361 295 0.678
regulation of mapk cascade GO:0043408 248 0.677
ribonucleoside metabolic process GO:0009119 245 0.670
nucleotide catabolic process GO:0009166 217 0.669
chemotaxis GO:0006935 247 0.668
Worm
regulation of protein kinase activity GO:0045859 232 0.657
nucleotide metabolic process GO:0009117 332 0.656
ribose phosphate metabolic process GO:0019693 291 0.634
ribonucleotide metabolic process GO:0009259 291 0.626
regionalization GO:0003002 337 0.623
axonogenesis GO:0007409 274 0.621
Mouse Worm
regulation of cellular amine metabolic process GO:0033238 20 0.615
microtubule based movement GO:0007018 84 0.611
membrane organization GO:0061024 245 0.610
purine ribonucleotide metabolic process GO:0009150 290 0.610
nucleoside catabolic process GO:0009164 206 0.601
nuclear division GO:0000280 158 0.599
male gamete generation GO:0048232 285 0.592
digestive tract development GO:0048565 190 0.582
cell division GO:0051301 120 0.578
Human
synaptic transmission GO:0007268 329 0.575
endomembrane system organization GO:0010256 147 0.569
ribonucleoside triphosphate metabolic process GO:0009199 220 0.566
protein localization to plasma membrane GO:0072659 57 0.566
actin cytoskeleton organization GO:0030036 220 0.565
pole plasm assembly GO:0007315 2 0.562
organophosphate catabolic process GO:0046434 232 0.558
nucleoside monophosphate metabolic process GO:0009123 85 0.541
ribonucleotide catabolic process GO:0009261 208 0.541
camera type eye development GO:0043010 266 0.539
ras protein signal transduction GO:0007265 77 0.531
regulation of neuron differentiation GO:0045664 281 0.529
plasma membrane organization GO:0007009 90 0.520
digestive tract morphogenesis GO:0048546 147 0.519
cellular nitrogen compound catabolic process GO:0044270 280 0.505
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.504
regulation of cellular amino acid metabolic process GO:0006521 5 0.497
mapk cascade GO:0000165 281 0.493
aromatic compound catabolic process GO:0019439 286 0.488
multicellular organism growth GO:0035264 161 0.487
Mouse
intracellular protein transport GO:0006886 204 0.486
cellular ion homeostasis GO:0006873 165 0.483
positive regulation of protein kinase activity GO:0045860 144 0.482
lymphocyte homeostasis GO:0002260 64 0.476
purine nucleotide catabolic process GO:0006195 211 0.470
nucleoside triphosphate metabolic process GO:0009141 230 0.469
digestive system development GO:0055123 200 0.468
regulation of transferase activity GO:0051338 263 0.467
negative regulation of growth GO:0045926 99 0.460
regulation of cell activation GO:0050865 289 0.457
calcium ion homeostasis GO:0055074 127 0.455
regulation of cellular component biogenesis GO:0044087 181 0.453
oocyte axis specification GO:0007309 2 0.445
purine nucleoside triphosphate metabolic process GO:0009144 226 0.442
oocyte construction GO:0007308 2 0.433
purine nucleoside metabolic process GO:0042278 241 0.432
regulation of ion transport GO:0043269 215 0.432
Mouse
axon guidance GO:0007411 141 0.429
Worm
spermatogenesis GO:0007283 284 0.426
olfactory learning GO:0008355 2 0.426
nucleoside monophosphate catabolic process GO:0009125 59 0.424
purine nucleoside catabolic process GO:0006152 205 0.421
oocyte anterior posterior axis specification GO:0007314 2 0.418
organonitrogen compound catabolic process GO:1901565 264 0.412
ribonucleoside triphosphate catabolic process GO:0009203 199 0.411
forebrain development GO:0030900 302 0.411
nucleoside phosphate catabolic process GO:1901292 222 0.408
regulation of cellular component size GO:0032535 121 0.402
regulation of neuron projection development GO:0010975 169 0.401
establishment of organelle localization GO:0051656 122 0.400
myeloid cell homeostasis GO:0002262 114 0.397
cognition GO:0050890 149 0.396
regulation of cell cycle GO:0051726 281 0.372
glycosyl compound metabolic process GO:1901657 246 0.371
cell adhesion GO:0007155 329 0.370
muscle system process GO:0003012 141 0.368
regulation of cell projection organization GO:0031344 206 0.358
oocyte differentiation GO:0009994 35 0.358
positive regulation of map kinase activity GO:0043406 84 0.354
regulation of organelle organization GO:0033043 289 0.348
mitotic cell cycle process GO:1903047 159 0.347
Human
carbohydrate derivative catabolic process GO:1901136 231 0.346
blood vessel morphogenesis GO:0048514 285 0.346
heterocycle catabolic process GO:0046700 280 0.345
gland development GO:0048732 330 0.343
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.336
negative regulation of protein metabolic process GO:0051248 282 0.336
cellular response to growth factor stimulus GO:0071363 197 0.324
cellular amine metabolic process GO:0044106 44 0.324
single organismal cell cell adhesion GO:0016337 131 0.323
small gtpase mediated signal transduction GO:0007264 97 0.322
nucleoside metabolic process GO:0009116 246 0.319
negative regulation of cell proliferation GO:0008285 296 0.317
purine nucleoside triphosphate catabolic process GO:0009146 203 0.316
neuron maturation GO:0042551 29 0.316
Mouse
regulation of kinase activity GO:0043549 249 0.315
epithelial cell development GO:0002064 159 0.315
cellular ketone metabolic process GO:0042180 84 0.313
positive regulation of apoptotic process GO:0043065 217 0.312
muscle tissue development GO:0060537 308 0.311
germ cell development GO:0007281 185 0.310
organelle fission GO:0048285 170 0.310
cation homeostasis GO:0055080 212 0.309
purine nucleoside monophosphate catabolic process GO:0009128 58 0.305
lymphocyte differentiation GO:0030098 242 0.303
ribonucleoside monophosphate catabolic process GO:0009158 57 0.303
striated muscle tissue development GO:0014706 293 0.301
wound healing GO:0042060 157 0.300
purine ribonucleoside catabolic process GO:0046130 205 0.299
muscle adaptation GO:0043500 39 0.299
peptidyl amino acid modification GO:0018193 336 0.295
Mouse
single organism cell adhesion GO:0098602 156 0.291
positive regulation of kinase activity GO:0033674 155 0.290
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.290
regulation of body fluid levels GO:0050878 162 0.288
cellular calcium ion homeostasis GO:0006874 119 0.284
cytosolic calcium ion homeostasis GO:0051480 70 0.282
regulation of purine nucleotide metabolic process GO:1900542 169 0.278
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.277
regulation of cell growth GO:0001558 91 0.275
cellular amino acid metabolic process GO:0006520 103 0.274
regulation of anatomical structure size GO:0090066 178 0.273
adherens junction assembly GO:0034333 22 0.271
cell substrate adhesion GO:0031589 130 0.271
actin filament based movement GO:0030048 23 0.268
regulation of protein serine threonine kinase activity GO:0071900 157 0.266
mitotic cell cycle GO:0000278 195 0.265
Human
regulation of binding GO:0051098 111 0.263
epithelial cell proliferation GO:0050673 174 0.263
calcium ion transport GO:0006816 159 0.260
divalent metal ion transport GO:0070838 172 0.259
regulation of synaptic plasticity GO:0048167 87 0.257
regulation of membrane potential GO:0042391 192 0.257
regulation of cell cycle process GO:0010564 160 0.255
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.255
positive regulation of cell development GO:0010720 237 0.253
regulation of hydrolase activity GO:0051336 246 0.250
cellular metal ion homeostasis GO:0006875 151 0.249
divalent inorganic cation transport GO:0072511 178 0.249
meiotic nuclear division GO:0007126 115 0.248
body morphogenesis GO:0010171 45 0.248
Worm
gastrulation GO:0007369 116 0.248
organelle assembly GO:0070925 177 0.248
atp catabolic process GO:0006200 55 0.243
cell maturation GO:0048469 127 0.243
Mouse
ameboidal type cell migration GO:0001667 128 0.242
ribonucleoside monophosphate metabolic process GO:0009161 80 0.242
developmental growth involved in morphogenesis GO:0060560 138 0.242
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.240
developmental maturation GO:0021700 193 0.240
Mouse
hemostasis GO:0007599 78 0.239
memory GO:0007613 58 0.234
associative learning GO:0008306 61 0.233
learning or memory GO:0007611 148 0.232
purine nucleoside monophosphate metabolic process GO:0009126 81 0.231
retina development in camera type eye GO:0060041 119 0.230
jnk cascade GO:0007254 72 0.228
cell junction assembly GO:0034329 52 0.228
microtubule based transport GO:0010970 50 0.224
leukocyte differentiation GO:0002521 342 0.222
protein localization to membrane GO:0072657 108 0.219
cell cell junction organization GO:0045216 72 0.219
mitochondrion transport along microtubule GO:0047497 3 0.217
muscle cell differentiation GO:0042692 261 0.217
regulation of lymphocyte activation GO:0051249 240 0.216
positive regulation of growth GO:0045927 104 0.214
Mouse
maintenance of location GO:0051235 89 0.214
spermatid development GO:0007286 108 0.212
negative regulation of phosphorylation GO:0042326 166 0.211
establishment of spindle localization GO:0051293 19 0.211
membrane depolarization GO:0051899 64 0.208
cytoskeleton dependent intracellular transport GO:0030705 50 0.208
divalent inorganic cation homeostasis GO:0072507 138 0.207
wnt signaling pathway GO:0016055 188 0.207
apoptotic signaling pathway GO:0097190 306 0.205
segmentation GO:0035282 93 0.199
negative regulation of cell cycle GO:0045786 123 0.198
purine containing compound catabolic process GO:0072523 213 0.197
negative regulation of phosphate metabolic process GO:0045936 184 0.195
negative regulation of cellular protein metabolic process GO:0032269 247 0.195
positive regulation of binding GO:0051099 49 0.194
meiotic cell cycle process GO:1903046 77 0.192
regulation of map kinase activity GO:0043405 120 0.191
negative regulation of mapk cascade GO:0043409 65 0.190
coagulation GO:0050817 78 0.190
regulation of nucleotide metabolic process GO:0006140 169 0.189
meiotic cell cycle GO:0051321 122 0.189
cytoplasmic transport GO:0016482 234 0.187
regulation of cellular ketone metabolic process GO:0010565 66 0.186
keratinocyte differentiation GO:0030216 48 0.186
regulation of muscle system process GO:0090257 80 0.185
positive regulation of nervous system development GO:0051962 221 0.183
positive regulation of cell substrate adhesion GO:0010811 47 0.183
macromolecule methylation GO:0043414 120 0.182
cellular divalent inorganic cation homeostasis GO:0072503 127 0.182
adherens junction organization GO:0034332 28 0.181
dna metabolic process GO:0006259 303 0.180
protein kinase b signaling GO:0043491 74 0.180
negative regulation of protein phosphorylation GO:0001933 126 0.179
mitochondrion organization GO:0007005 134 0.179
ion transmembrane transport GO:0034220 361 0.179
regulation of cell motility GO:2000145 236 0.178
leukocyte homeostasis GO:0001776 79 0.176
maternal determination of anterior posterior axis embryo GO:0008358 2 0.176
myeloid cell differentiation GO:0030099 233 0.173
blood coagulation GO:0007596 76 0.171
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.170
regulation of cell division GO:0051302 76 0.169
cell type specific apoptotic process GO:0097285 268 0.167
negative regulation of epithelial cell proliferation GO:0050680 64 0.167
telencephalon development GO:0021537 186 0.167
negative regulation of cellular amine metabolic process GO:0033239 1 0.167
positive regulation of mapk cascade GO:0043410 170 0.166
organelle localization GO:0051640 179 0.165
rhythmic process GO:0048511 174 0.164
regulation of intracellular transport GO:0032386 159 0.161
glycerolipid metabolic process GO:0046486 122 0.161
locomotory behavior GO:0007626 195 0.159
Mouse
regulation of jnk cascade GO:0046328 62 0.159
regulation of lymphocyte proliferation GO:0050670 117 0.158
regulation of protein binding GO:0043393 60 0.158
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.158
atp metabolic process GO:0046034 75 0.156
t cell proliferation GO:0042098 120 0.155
regulation of cell substrate adhesion GO:0010810 73 0.152
regulation of cellular response to stress GO:0080135 159 0.151
response to transforming growth factor beta GO:0071559 88 0.150
calcium ion transport into cytosol GO:0060402 48 0.150
exocytosis GO:0006887 121 0.150
negative regulation of cellular component organization GO:0051129 194 0.149
cytokinesis GO:0000910 17 0.148
Human
regulation of postsynaptic membrane potential GO:0060078 48 0.148
establishment or maintenance of cell polarity GO:0007163 86 0.148
positive regulation of neuron projection development GO:0010976 79 0.147
learning GO:0007612 98 0.147
neuron migration GO:0001764 122 0.146
cytosolic calcium ion transport GO:0060401 48 0.146
positive regulation of ras gtpase activity GO:0032320 65 0.145
negative regulation of cell growth GO:0030308 44 0.145
gonad development GO:0008406 141 0.145
t cell activation GO:0042110 289 0.145
mitotic nuclear division GO:0007067 48 0.145
positive regulation of transferase activity GO:0051347 167 0.144
cellular response to dna damage stimulus GO:0006974 207 0.144
extrinsic apoptotic signaling pathway GO:0097191 126 0.144
circulatory system process GO:0003013 197 0.144
Mouse
release of sequestered calcium ion into cytosol GO:0051209 42 0.140
epithelial cell morphogenesis GO:0003382 41 0.140
spindle localization GO:0051653 22 0.139
activation of mapk activity GO:0000187 59 0.139
regulation of cell adhesion GO:0030155 154 0.136
intracellular mrna localization GO:0008298 4 0.135
positive regulation of hydrolase activity GO:0051345 148 0.135
axon cargo transport GO:0008088 33 0.134
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.132
regulation of actin cytoskeleton organization GO:0032956 84 0.132
cell migration involved in gastrulation GO:0042074 13 0.131
regulation of cytoskeleton organization GO:0051493 122 0.131
cell fate commitment GO:0045165 210 0.130
cellular component assembly involved in morphogenesis GO:0010927 139 0.130
neuron death GO:0070997 154 0.129
regulation of homeostatic process GO:0032844 182 0.129
skeletal system morphogenesis GO:0048705 203 0.129
mitochondrion distribution GO:0048311 4 0.128
oogenesis GO:0048477 56 0.126
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.126
fertilization GO:0009566 127 0.125
Mouse
cell growth GO:0016049 130 0.125
regulation of establishment of protein localization GO:0070201 181 0.124
negative regulation of lymphocyte activation GO:0051250 91 0.124
sequestering of calcium ion GO:0051208 18 0.123
myotube differentiation GO:0014902 105 0.123
regulation of cell size GO:0008361 72 0.123
regulation of apoptotic signaling pathway GO:2001233 197 0.123
regulation of cellular catabolic process GO:0031329 242 0.123
posttranscriptional regulation of gene expression GO:0010608 155 0.122
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.121
response to organonitrogen compound GO:0010243 246 0.121
positive regulation of cellular amine metabolic process GO:0033240 5 0.121
response to growth factor GO:0070848 198 0.120
lymphocyte proliferation GO:0046651 164 0.117
regulation of reproductive process GO:2000241 66 0.115
lateral inhibition GO:0046331 1 0.115
negative regulation of phosphorus metabolic process GO:0010563 184 0.115
generation of precursor metabolites and energy GO:0006091 103 0.115
regulation of cell migration GO:0030334 219 0.114
g1 s transition of mitotic cell cycle GO:0000082 57 0.114
regulation of circadian sleep wake cycle GO:0042749 3 0.114
positive regulation of protein modification process GO:0031401 299 0.113
epithelial tube morphogenesis GO:0060562 303 0.112
regulation of epithelial cell proliferation GO:0050678 141 0.111
negative regulation of protein modification process GO:0031400 163 0.110
circadian rhythm GO:0007623 114 0.110
regulation of neuron apoptotic process GO:0043523 122 0.109
positive regulation of programmed cell death GO:0043068 218 0.109
skin development GO:0043588 220 0.108
response to oxidative stress GO:0006979 123 0.108
multi multicellular organism process GO:0044706 109 0.108
cyclic nucleotide metabolic process GO:0009187 59 0.107
sensory perception of sound GO:0007605 97 0.107
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.107
lateral line system development GO:0048925 1 0.107
second messenger mediated signaling GO:0019932 73 0.106
striated muscle adaptation GO:0014888 26 0.106
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.105
macromolecule catabolic process GO:0009057 281 0.105
myeloid leukocyte differentiation GO:0002573 119 0.105
cellular homeostasis GO:0019725 240 0.104
Worm
peptidyl tyrosine phosphorylation GO:0018108 143 0.104
glutamate receptor signaling pathway GO:0007215 35 0.103
leukocyte proliferation GO:0070661 172 0.103
midgut development GO:0007494 4 0.103
negative regulation of immune system process GO:0002683 209 0.103
regulation of leukocyte proliferation GO:0070663 121 0.102
amine metabolic process GO:0009308 45 0.102
establishment of mitochondrion localization GO:0051654 4 0.102
regulation of leukocyte differentiation GO:1902105 159 0.101
stem cell development GO:0048864 219 0.100
striated muscle myosin thick filament assembly GO:0071688 1 0.099
epidermis development GO:0008544 187 0.099
erythrocyte differentiation GO:0030218 88 0.098
stress activated protein kinase signaling cascade GO:0031098 81 0.097
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.096
regulation of response to wounding GO:1903034 189 0.096
neuron projection guidance GO:0097485 141 0.096
Worm
embryonic organ morphogenesis GO:0048562 276 0.096
liver development GO:0001889 66 0.095
neuron projection extension GO:1990138 64 0.095
skeletal muscle organ development GO:0060538 163 0.094
negative regulation of protein processing GO:0010955 79 0.094
regulation of system process GO:0044057 200 0.094
Mouse
dephosphorylation GO:0016311 129 0.094
regulation of t cell activation GO:0050863 170 0.093
protein autophosphorylation GO:0046777 61 0.093
angiogenesis GO:0001525 201 0.092
transmembrane transport GO:0055085 412 0.092
guanosine containing compound catabolic process GO:1901069 144 0.092
regulation of ion homeostasis GO:2000021 64 0.091
platelet activation GO:0030168 40 0.091
cellular chemical homeostasis GO:0055082 215 0.091
regulation of mitotic cell cycle GO:0007346 126 0.091
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.091
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.090
neuron neuron synaptic transmission GO:0007270 69 0.090
cell cycle g1 s phase transition GO:0044843 57 0.090
camp metabolic process GO:0046058 40 0.090
neuron apoptotic process GO:0051402 142 0.089
renal system development GO:0072001 225 0.089
formation of primary germ layer GO:0001704 77 0.088
g protein coupled receptor signaling pathway GO:0007186 243 0.088
developmental cell growth GO:0048588 84 0.088
response to acid chemical GO:0001101 111 0.088
sensory perception GO:0007600 245 0.087
Mouse
regulation of ion transmembrane transporter activity GO:0032412 54 0.087
cerebellum development GO:0021549 77 0.087
Mouse
homotypic cell cell adhesion GO:0034109 28 0.086
regulation of protein processing GO:0070613 96 0.086
positive regulation of protein binding GO:0032092 29 0.086
cardiac muscle hypertrophy in response to stress GO:0014898 10 0.085
anatomical structure homeostasis GO:0060249 145 0.083
Worm
cell junction organization GO:0034330 77 0.083
establishment of protein localization to membrane GO:0090150 54 0.082
positive regulation of lymphocyte proliferation GO:0050671 70 0.081
regulation of focal adhesion assembly GO:0051893 12 0.080
regulation of neurotransmitter secretion GO:0046928 29 0.080
negative regulation of apoptotic signaling pathway GO:2001234 104 0.080
regulation of cytoplasmic transport GO:1903649 112 0.080
skeletal system development GO:0001501 356 0.079
sequestering of metal ion GO:0051238 19 0.079
golgi localization GO:0051645 4 0.079
regulation of neuron death GO:1901214 134 0.078
spindle organization GO:0007051 28 0.078
carbohydrate homeostasis GO:0033500 128 0.078
establishment of protein localization to plasma membrane GO:0090002 34 0.077
regulation of calcium ion transport GO:0051924 69 0.077
negative regulation of neuron differentiation GO:0045665 101 0.077
negative regulation of molecular function GO:0044092 258 0.076
tissue remodeling GO:0048771 102 0.076
positive regulation of protein phosphorylation GO:0001934 242 0.076
potassium ion transport GO:0006813 52 0.075
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.075
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.075
neural tube development GO:0021915 160 0.074
regulation of actin filament based process GO:0032970 99 0.074
response to radiation GO:0009314 165 0.074
regulation of protein localization GO:0032880 231 0.074
nucleus localization GO:0051647 20 0.074
cellular macromolecule catabolic process GO:0044265 206 0.074
neurotransmitter secretion GO:0007269 62 0.074
platelet aggregation GO:0070527 20 0.073
negative regulation of synapse assembly GO:0051964 3 0.072
synapse organization GO:0050808 125 0.072
Mouse
leukocyte migration GO:0050900 124 0.072
leukocyte mediated immunity GO:0002443 174 0.072
regulation of heart contraction GO:0008016 77 0.072
Mouse
nitrogen compound transport GO:0071705 271 0.071
positive regulation of organelle organization GO:0010638 128 0.071
inflammatory response GO:0006954 244 0.071
urogenital system development GO:0001655 261 0.071
sensory perception of mechanical stimulus GO:0050954 107 0.071
Mouse
multicellular organismal reproductive behavior GO:0033057 23 0.071
regulation of erk1 and erk2 cascade GO:0070372 71 0.070
regulation of multi organism process GO:0043900 111 0.070
peptidyl tyrosine modification GO:0018212 145 0.070
female gamete generation GO:0007292 74 0.070
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.070
cerebellar cortex development GO:0021695 48 0.070
Mouse
negative regulation of cell activation GO:0050866 111 0.069
inorganic ion transmembrane transport GO:0098660 234 0.069
cellular response to lipid GO:0071396 145 0.069
cell matrix adhesion GO:0007160 68 0.069
regulation of transmembrane transport GO:0034762 128 0.069
asymmetric stem cell division GO:0098722 3 0.069
regulation of gtp catabolic process GO:0033124 113 0.069
cellular response to extracellular stimulus GO:0031668 81 0.068
negative regulation of intracellular signal transduction GO:1902532 167 0.068
extracellular matrix organization GO:0030198 147 0.068
rhodopsin mediated signaling pathway GO:0016056 4 0.067
positive regulation of cell cycle GO:0045787 92 0.067
regulation of defense response GO:0031347 233 0.066
inorganic cation transmembrane transport GO:0098662 207 0.066
kidney development GO:0001822 213 0.066
stem cell differentiation GO:0048863 268 0.066
positive regulation of neuron differentiation GO:0045666 141 0.066
regulation of stress activated mapk cascade GO:0032872 69 0.066
multi organism behavior GO:0051705 62 0.065
spermatid differentiation GO:0048515 115 0.065
protein processing GO:0016485 163 0.065
negative regulation of mitotic cell cycle GO:0045930 58 0.065
regulation of cell projection assembly GO:0060491 38 0.065
negative regulation of homeostatic process GO:0032845 71 0.065
regulation of metal ion transport GO:0010959 106 0.063
Mouse
regulation of protein maturation GO:1903317 96 0.063
immune response activating signal transduction GO:0002757 116 0.062
positive regulation of cell cycle process GO:0090068 61 0.062
histone lysine methylation GO:0034968 50 0.061
response to organic cyclic compound GO:0014070 198 0.061
regulation of t cell proliferation GO:0042129 92 0.060
substrate adhesion dependent cell spreading GO:0034446 30 0.060
cell substrate junction assembly GO:0007044 24 0.060
regulation of sarcomere organization GO:0060297 4 0.060
regulation of protein kinase b signaling GO:0051896 56 0.060
sister chromatid segregation GO:0000819 20 0.059
peptidyl threonine phosphorylation GO:0018107 31 0.059
muscle cell development GO:0055001 133 0.059
myosin filament assembly GO:0031034 2 0.059
positive regulation of cell activation GO:0050867 158 0.059
regulation of secretion by cell GO:1903530 249 0.059
peptidyl threonine modification GO:0018210 31 0.059
embryonic skeletal system development GO:0048706 120 0.058
methylation GO:0032259 134 0.058
striated muscle cell development GO:0055002 125 0.058
negative regulation of kinase activity GO:0033673 81 0.058
positive regulation of cell adhesion GO:0045785 80 0.058
cation transmembrane transport GO:0098655 266 0.057
apical constriction GO:0003383 4 0.057
development of primary sexual characteristics GO:0045137 143 0.057
actomyosin structure organization GO:0031032 56 0.057
cell substrate adherens junction assembly GO:0007045 19 0.056
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.056
action potential GO:0001508 78 0.056
positive regulation of calcium ion transmembrane transporter activity GO:1901021 8 0.055
multicellular organismal homeostasis GO:0048871 164 0.055
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.055
energy derivation by oxidation of organic compounds GO:0015980 77 0.054

Spnb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.284
nervous system disease DOID:863 0 0.284
central nervous system disease DOID:331 0 0.134
brain disease DOID:936 0 0.134
neuromuscular disease DOID:440 0 0.128
charcot marie tooth disease DOID:10595 0 0.128
neuropathy DOID:870 0 0.128
cancer DOID:162 0 0.108
disease of cellular proliferation DOID:14566 0 0.108
organ system cancer DOID:0050686 0 0.108
epilepsy syndrome DOID:1826 0 0.079
electroclinical syndrome DOID:0050701 0 0.079
neonatal period electroclinical syndrome DOID:0050702 0 0.079