Mus musculus

159 known processes

Spnb4

spectrin beta 4

(Aliases: nmf379,nmf261,qv,1700022P15Rik,dyn,ROSA62,SpbIV,lnd,5830426A08Rik)

Spnb4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of membrane potential GO:0042391 192 0.264
ion transmembrane transport GO:0034220 361 0.204
transmembrane transport GO:0055085 412 0.196
regulation of ion transport GO:0043269 215 0.191
cation transport GO:0006812 399 0.143
cellular nitrogen compound catabolic process GO:0044270 280 0.137
inorganic ion transmembrane transport GO:0098660 234 0.125
carbohydrate derivative catabolic process GO:1901136 231 0.121
organophosphate catabolic process GO:0046434 232 0.114
divalent metal ion transport GO:0070838 172 0.109
anatomical structure homeostasis GO:0060249 145 0.107
Worm
membrane organization GO:0061024 245 0.104
nucleoside triphosphate catabolic process GO:0009143 205 0.102
ribonucleoside triphosphate catabolic process GO:0009203 199 0.101
ribonucleotide catabolic process GO:0009261 208 0.101
organic cyclic compound catabolic process GO:1901361 295 0.099
aromatic compound catabolic process GO:0019439 286 0.098
exocytosis GO:0006887 121 0.096
purine ribonucleotide catabolic process GO:0009154 208 0.092
nucleoside phosphate catabolic process GO:1901292 222 0.091
regulation of cellular ketone metabolic process GO:0010565 66 0.089
spermatogenesis GO:0007283 284 0.088
guanosine containing compound catabolic process GO:1901069 144 0.087
heterocycle catabolic process GO:0046700 280 0.086
purine nucleoside triphosphate catabolic process GO:0009146 203 0.084
regulation of transmembrane transport GO:0034762 128 0.081
germ cell development GO:0007281 185 0.081
purine nucleoside metabolic process GO:0042278 241 0.080
purine nucleoside catabolic process GO:0006152 205 0.080
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.079
ribonucleoside catabolic process GO:0042454 206 0.078
purine ribonucleotide metabolic process GO:0009150 290 0.074
glycosyl compound metabolic process GO:1901657 246 0.073
purine nucleoside triphosphate metabolic process GO:0009144 226 0.072
purine ribonucleoside catabolic process GO:0046130 205 0.072
regulation of vesicle mediated transport GO:0060627 139 0.072
organonitrogen compound catabolic process GO:1901565 264 0.072
cellular response to dna damage stimulus GO:0006974 207 0.072
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.069
nucleotide metabolic process GO:0009117 332 0.068
multicellular organismal signaling GO:0035637 91 0.068
male gamete generation GO:0048232 285 0.068
synaptic vesicle localization GO:0097479 59 0.063
ras protein signal transduction GO:0007265 77 0.063
positive regulation of gtp catabolic process GO:0033126 85 0.063
purine containing compound catabolic process GO:0072523 213 0.062
nucleoside triphosphate metabolic process GO:0009141 230 0.062
nucleoside metabolic process GO:0009116 246 0.058
transmission of nerve impulse GO:0019226 76 0.057
chemotaxis GO:0006935 247 0.057
Worm
nucleoside phosphate metabolic process GO:0006753 338 0.056
vesicle localization GO:0051648 86 0.054
nucleoside catabolic process GO:0009164 206 0.053
meiotic nuclear division GO:0007126 115 0.052
purine nucleotide metabolic process GO:0006163 302 0.049
regulation of transferase activity GO:0051338 263 0.049
cellular divalent inorganic cation homeostasis GO:0072503 127 0.049
cation homeostasis GO:0055080 212 0.049
glycosyl compound catabolic process GO:1901658 206 0.049
positive regulation of cell death GO:0010942 224 0.049
macromolecule catabolic process GO:0009057 281 0.049
positive regulation of programmed cell death GO:0043068 218 0.048
inorganic cation transmembrane transport GO:0098662 207 0.047
meiotic cell cycle process GO:1903046 77 0.046
gtp metabolic process GO:0046039 144 0.046
regulation of hydrolase activity GO:0051336 246 0.045
negative regulation of protein metabolic process GO:0051248 282 0.045
nucleobase containing small molecule metabolic process GO:0055086 352 0.045
negative regulation of molecular function GO:0044092 258 0.045
ribonucleoside metabolic process GO:0009119 245 0.044
purine ribonucleoside metabolic process GO:0046128 241 0.044
purine nucleotide catabolic process GO:0006195 211 0.044
ensheathment of neurons GO:0007272 76 0.044
cellular ion homeostasis GO:0006873 165 0.044
dna metabolic process GO:0006259 303 0.044
neuronal action potential GO:0019228 54 0.043
ribonucleoside triphosphate metabolic process GO:0009199 220 0.043
ribose phosphate metabolic process GO:0019693 291 0.042
divalent inorganic cation homeostasis GO:0072507 138 0.041
nucleotide catabolic process GO:0009166 217 0.041
developmental maturation GO:0021700 193 0.040
potassium ion transmembrane transport GO:0071805 43 0.040
regulation of protein kinase activity GO:0045859 232 0.039
cation transmembrane transport GO:0098655 266 0.039
regulation of protein localization GO:0032880 231 0.039
spermatid development GO:0007286 108 0.038
cellular amino acid metabolic process GO:0006520 103 0.038
microtubule based movement GO:0007018 84 0.037
action potential GO:0001508 78 0.037
cellular chemical homeostasis GO:0055082 215 0.037
gtp catabolic process GO:0006184 143 0.036
negative regulation of phosphorylation GO:0042326 166 0.036
ribonucleotide metabolic process GO:0009259 291 0.036
guanosine containing compound metabolic process GO:1901068 144 0.035
organelle fission GO:0048285 170 0.035
regulation of gtp catabolic process GO:0033124 113 0.035
peptidyl amino acid modification GO:0018193 336 0.034
regulation of ion transmembrane transport GO:0034765 119 0.034
multicellular organism growth GO:0035264 161 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.033
small gtpase mediated signal transduction GO:0007264 97 0.033
glycerophospholipid metabolic process GO:0006650 71 0.033
establishment of vesicle localization GO:0051650 81 0.033
regulation of metal ion transport GO:0010959 106 0.033
cell adhesion GO:0007155 329 0.033
regulation of proteolysis GO:0030162 164 0.032
regulation of cellular catabolic process GO:0031329 242 0.032
meiotic cell cycle GO:0051321 122 0.031
divalent inorganic cation transport GO:0072511 178 0.031
purine containing compound metabolic process GO:0072521 311 0.031
regulation of establishment of protein localization GO:0070201 181 0.031
cellular homeostasis GO:0019725 240 0.030
Worm
regulation of synaptic plasticity GO:0048167 87 0.030
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
regulation of glutamate receptor signaling pathway GO:1900449 16 0.029
myelination in peripheral nervous system GO:0022011 19 0.028
regulation of cell projection organization GO:0031344 206 0.028
regulation of organelle organization GO:0033043 289 0.027
synaptic transmission GO:0007268 329 0.027
cellular calcium ion homeostasis GO:0006874 119 0.027
positive regulation of cellular catabolic process GO:0031331 148 0.027
tissue homeostasis GO:0001894 115 0.027
cellularization GO:0007349 1 0.026
calcium ion dependent exocytosis GO:0017156 35 0.026
calcium ion homeostasis GO:0055074 127 0.026
negative regulation of cellular amine metabolic process GO:0033239 1 0.026
regulation of homeostatic process GO:0032844 182 0.025
rna processing GO:0006396 105 0.025
cellular ketone metabolic process GO:0042180 84 0.025
regulation of purine nucleotide catabolic process GO:0033121 122 0.025
regulation of intracellular transport GO:0032386 159 0.025
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.025
actin cytoskeleton organization GO:0030036 220 0.025
regulation of secretion by cell GO:1903530 249 0.025
eosinophil migration GO:0072677 3 0.025
response to inactivity GO:0014854 4 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
organelle localization GO:0051640 179 0.023
leukocyte differentiation GO:0002521 342 0.023
glycerolipid metabolic process GO:0046486 122 0.023
establishment of organelle localization GO:0051656 122 0.023
response to peptide GO:1901652 136 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
circulatory system process GO:0003013 197 0.022
nuclear division GO:0000280 158 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
renal sodium ion transport GO:0003096 2 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
positive regulation of nucleoside metabolic process GO:0045979 91 0.022
microtubule based process GO:0007017 236 0.022
regulation of nucleotide catabolic process GO:0030811 122 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
protein maturation GO:0051604 176 0.022
axon ensheathment GO:0008366 76 0.021
thymocyte migration GO:0072679 2 0.021
positive regulation of gtpase activity GO:0043547 85 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
engulfment of apoptotic cell GO:0043652 3 0.021
metal ion homeostasis GO:0055065 189 0.021
protein autophosphorylation GO:0046777 61 0.020
skin development GO:0043588 220 0.020
establishment of synaptic vesicle localization GO:0097480 57 0.020
single organism cell adhesion GO:0098602 156 0.020
single organismal cell cell adhesion GO:0016337 131 0.020
cell chemotaxis GO:0060326 81 0.019
oxidation reduction process GO:0055114 342 0.019
spermatid differentiation GO:0048515 115 0.019
synaptic vesicle transport GO:0048489 57 0.019
mrna metabolic process GO:0016071 84 0.019
protein catabolic process GO:0030163 221 0.019
regulation of kinase activity GO:0043549 249 0.019
calcium ion transport GO:0006816 159 0.019
regulation of cellular response to stress GO:0080135 159 0.019
rap protein signal transduction GO:0032486 3 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
Mouse
plasma membrane organization GO:0007009 90 0.019
intracellular mrna localization GO:0008298 4 0.018
potassium ion transport GO:0006813 52 0.018
negative regulation of protein maturation GO:1903318 79 0.018
muscle system process GO:0003012 141 0.018
phospholipid metabolic process GO:0006644 87 0.018
mapk cascade GO:0000165 281 0.018
regulation of cell adhesion GO:0030155 154 0.018
response to lipopolysaccharide GO:0032496 128 0.018
oocyte axis specification GO:0007309 2 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
cell maturation GO:0048469 127 0.018
regulation of bone resorption GO:0045124 24 0.018
regulation of thymocyte migration GO:2000410 2 0.018
positive regulation of proteolysis GO:0045862 85 0.018
positive regulation of intracellular transport GO:0032388 70 0.017
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.017
cell division GO:0051301 120 0.017
meiosis i GO:0007127 60 0.017
regulation of t cell activation GO:0050863 170 0.017
t cell activation GO:0042110 289 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
myeloid cell homeostasis GO:0002262 114 0.017
cell growth GO:0016049 130 0.017
dephosphorylation GO:0016311 129 0.017
response to inorganic substance GO:0010035 96 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
regulation of exocytosis GO:0017157 61 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.017
gene silencing GO:0016458 38 0.017
regulation of endocytosis GO:0030100 69 0.016
single fertilization GO:0007338 82 0.016
phagocytosis GO:0006909 66 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
sequestering of metal ion GO:0051238 19 0.016
amine metabolic process GO:0009308 45 0.016
glial cell development GO:0021782 54 0.016
cytosolic calcium ion homeostasis GO:0051480 70 0.016
rna interference GO:0016246 2 0.016
regulation of protein transport GO:0051223 163 0.016
endocytosis GO:0006897 168 0.016
immune effector process GO:0002252 321 0.016
adaptive immune response GO:0002250 155 0.016
cell recognition GO:0008037 83 0.016
Worm
negative regulation of protein processing GO:0010955 79 0.016
regulation of mrna metabolic process GO:1903311 43 0.016
protein processing GO:0016485 163 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
oocyte construction GO:0007308 2 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.015
potassium ion homeostasis GO:0055075 4 0.015
pma inducible membrane protein ectodomain proteolysis GO:0051088 1 0.015
regulation of ras protein signal transduction GO:0046578 114 0.015
regulation of cellular component size GO:0032535 121 0.015
homeostasis of number of cells GO:0048872 210 0.015
regulation of protein processing GO:0070613 96 0.015
neurotransmitter secretion GO:0007269 62 0.015
cellular potassium ion transport GO:0071804 43 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
positive regulation of thymocyte migration GO:2000412 2 0.015
cellular amine metabolic process GO:0044106 44 0.015
cell type specific apoptotic process GO:0097285 268 0.015
membrane depolarization GO:0051899 64 0.015
male meiosis GO:0007140 37 0.015
regulation of eosinophil migration GO:2000416 2 0.015
myeloid cell differentiation GO:0030099 233 0.014
positive regulation of neuron projection development GO:0010976 79 0.014
glutamate receptor signaling pathway GO:0007215 35 0.014
cytoskeleton dependent intracellular transport GO:0030705 50 0.014
endomembrane system organization GO:0010256 147 0.014
mrna processing GO:0006397 63 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
regulation of protein catabolic process GO:0042176 108 0.014
negative regulation of membrane potential GO:0045837 4 0.014
hormone metabolic process GO:0042445 86 0.014
mitotic cytokinesis GO:0000281 4 0.014
apoptotic signaling pathway GO:0097190 306 0.014
innate immune response GO:0045087 157 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
axon cargo transport GO:0008088 33 0.014
regulation of gamma aminobutyric acid secretion GO:0014052 2 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
developmental cell growth GO:0048588 84 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
regulation of anatomical structure size GO:0090066 178 0.014
negative regulation of hydrolase activity GO:0051346 71 0.014
response to insulin GO:0032868 100 0.013
sequestering of calcium ion GO:0051208 18 0.013
lymphocyte differentiation GO:0030098 242 0.013
regulation of cell cycle process GO:0010564 160 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
regulation of ion homeostasis GO:2000021 64 0.013
regulation of ras gtpase activity GO:0032318 88 0.013
nucleoside monophosphate catabolic process GO:0009125 59 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
regulation of actin filament based process GO:0032970 99 0.013
blood circulation GO:0008015 195 0.013
synapse organization GO:0050808 125 0.013
Mouse
regulation of peptidase activity GO:0052547 96 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
regulation of mapk cascade GO:0043408 248 0.013
peptidyl tyrosine phosphorylation GO:0018108 143 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
positive regulation of nervous system development GO:0051962 221 0.013
regulation of translation GO:0006417 71 0.013
schwann cell development GO:0014044 22 0.013
negative regulation of protein modification process GO:0031400 163 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
Mouse
positive regulation of eosinophil migration GO:2000418 2 0.013
cardiac muscle cell contraction GO:0086003 7 0.013
atp metabolic process GO:0046034 75 0.013
regulation of transporter activity GO:0032409 57 0.013
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.012
photoreceptor cell differentiation GO:0046530 52 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
positive regulation of endocytosis GO:0045807 42 0.012
cognition GO:0050890 149 0.012
lymphocyte proliferation GO:0046651 164 0.012
vesicle organization GO:0016050 60 0.012
positive regulation of protein transport GO:0051222 93 0.012
regulation of cell size GO:0008361 72 0.012
peptidyl serine phosphorylation GO:0018105 74 0.012
organelle assembly GO:0070925 177 0.012
regulation of multi organism process GO:0043900 111 0.012
positive regulation of protein modification process GO:0031401 299 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
defense response to other organism GO:0098542 197 0.012
glycoprotein metabolic process GO:0009100 116 0.012
regulation of cell cycle GO:0051726 281 0.012
positive regulation of t cell activation GO:0050870 101 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
regulation of neuron projection development GO:0010975 169 0.012
prevention of polyspermy GO:0060468 4 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
positive regulation of organelle organization GO:0010638 128 0.011
microtubule based transport GO:0010970 50 0.011
negative regulation of proteolysis GO:0045861 74 0.011
negative regulation of kinase activity GO:0033673 81 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
cytokine production GO:0001816 319 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.011
inflammatory response GO:0006954 244 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
insulin receptor signaling pathway GO:0008286 49 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
regulation of protein maturation GO:1903317 96 0.011
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
regulation of actin filament length GO:0030832 45 0.011
response to organic cyclic compound GO:0014070 198 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
female gamete generation GO:0007292 74 0.011
rho protein signal transduction GO:0007266 32 0.011
hindbrain development GO:0030902 128 0.011
Mouse
protein ubiquitination GO:0016567 171 0.011
glycerolipid biosynthetic process GO:0045017 50 0.011
regulation of tissue remodeling GO:0034103 38 0.010
myelination GO:0042552 74 0.010
phosphatidylinositol metabolic process GO:0046488 45 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
mitotic cell cycle GO:0000278 195 0.010
activation of mapk activity involved in innate immune response GO:0035419 2 0.010
response to peptide hormone GO:0043434 127 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.010
regulation of defense response GO:0031347 233 0.010
learning or memory GO:0007611 148 0.010
positive regulation of transferase activity GO:0051347 167 0.010
extracellular structure organization GO:0043062 148 0.010
cellular lipid metabolic process GO:0044255 323 0.010
fibronectin dependent thymocyte migration GO:0072681 1 0.010
leukocyte proliferation GO:0070661 172 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
pole plasm assembly GO:0007315 2 0.010
nuclear transport GO:0051169 139 0.010
Mouse
positive regulation of ion transport GO:0043270 65 0.010
protein glycosylation GO:0006486 55 0.010
positive regulation of kinase activity GO:0033674 155 0.010
regulation of cell motility GO:2000145 236 0.010
mitotic cell cycle process GO:1903047 159 0.010
regulation of cell activation GO:0050865 289 0.010
inner ear receptor stereocilium organization GO:0060122 23 0.010
regulation of mrna processing GO:0050684 41 0.010
detection of external stimulus GO:0009581 61 0.010
tumor necrosis factor ligand superfamily member 11 production GO:0072535 1 0.010
camera type eye development GO:0043010 266 0.010
regulation of intracellular protein transport GO:0033157 82 0.010

Spnb4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.018
disease of anatomical entity DOID:7 0 0.018
musculoskeletal system disease DOID:17 0 0.015
bone development disease DOID:0080006 0 0.015
osteochondrodysplasia DOID:2256 0 0.015
bone disease DOID:0080001 0 0.015
connective tissue disease DOID:65 0 0.015
sensory system disease DOID:0050155 0 0.013
central nervous system disease DOID:331 0 0.011