Mus musculus

69 known processes

Hras1

Harvey rat sarcoma virus oncogene 1

(Aliases: Hras-1,H-ras,Kras2,c-rasHa,c-H-ras,c-Ha-ras,ras,Ha-ras,Harvey-ras)

Hras1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 187 0.351
regulation of cellular amine metabolic process GO:0033238 20 0.291
regionalization GO:0003002 337 0.264
Fly
positive regulation of protein modification process GO:0031401 299 0.250
Human
regulation of cell migration GO:0030334 219 0.231
Human Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.188
regulation of cell motility GO:2000145 236 0.174
Human Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.167
positive regulation of mapk cascade GO:0043410 170 0.153
Human Rat Fly
regulation of transferase activity GO:0051338 263 0.135
Human
positive regulation of cellular amine metabolic process GO:0033240 5 0.134
regulation of cellular catabolic process GO:0031329 242 0.115
Human Worm Fly
ras protein signal transduction GO:0007265 77 0.113
Human Mouse Rat
negative regulation of phosphorus metabolic process GO:0010563 184 0.104
Human
cellular amino acid metabolic process GO:0006520 103 0.100
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.099
protein targeting GO:0006605 143 0.098
Fly
male gamete generation GO:0048232 285 0.095
positive regulation of neuron differentiation GO:0045666 141 0.094
Fly
cellular ketone metabolic process GO:0042180 84 0.093
cell substrate adhesion GO:0031589 130 0.090
carbohydrate derivative biosynthetic process GO:1901137 183 0.084
Yeast
response to hypoxia GO:0001666 58 0.082
membrane organization GO:0061024 245 0.081
organophosphate catabolic process GO:0046434 232 0.077
Human Yeast Mouse Worm Fly
cytoplasmic transport GO:0016482 234 0.073
Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.073
regulation of wnt signaling pathway GO:0030111 123 0.068
erbb signaling pathway GO:0038127 32 0.067
Worm
cellular lipid metabolic process GO:0044255 323 0.065
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.064
compound eye development GO:0048749 1 0.064
Fly
negative regulation of cell proliferation GO:0008285 296 0.063
Human
proteasomal protein catabolic process GO:0010498 98 0.062
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.060
Worm
organelle localization GO:0051640 179 0.059
regulation of secretion GO:0051046 274 0.059
Mouse
muscle cell development GO:0055001 133 0.059
cellular protein catabolic process GO:0044257 155 0.058
peptidyl serine phosphorylation GO:0018105 74 0.057
negative regulation of camp mediated signaling GO:0043951 3 0.055
protein catabolic process GO:0030163 221 0.055
negative regulation of molecular function GO:0044092 258 0.055
Human
amine metabolic process GO:0009308 45 0.055
wnt signaling pathway GO:0016055 188 0.055
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.054
Human Rat
regulation of mapk cascade GO:0043408 248 0.054
Human Rat Fly
peptidyl serine modification GO:0018209 83 0.054
cellular amine metabolic process GO:0044106 44 0.052
protein ubiquitination GO:0016567 171 0.052
vesicle localization GO:0051648 86 0.051
modification dependent macromolecule catabolic process GO:0043632 133 0.051
establishment of organelle localization GO:0051656 122 0.050
placenta development GO:0001890 140 0.050
spermatogenesis GO:0007283 284 0.048
response to light stimulus GO:0009416 135 0.047
Mouse
ovarian follicle development GO:0001541 40 0.046
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.046
protein autophosphorylation GO:0046777 61 0.045
small gtpase mediated signal transduction GO:0007264 97 0.045
response to radiation GO:0009314 165 0.045
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.043
positive regulation of hydrolase activity GO:0051345 148 0.042
Human Worm
cellular component assembly involved in morphogenesis GO:0010927 139 0.042
negative regulation of synaptic vesicle transport GO:1902804 3 0.042
negative regulation of cell migration GO:0030336 59 0.041
Mouse
ameboidal type cell migration GO:0001667 128 0.041
Fly
organelle assembly GO:0070925 177 0.041
protein localization to membrane GO:0072657 108 0.041
protein processing GO:0016485 163 0.040
skeletal muscle organ development GO:0060538 163 0.040
Mouse
t cell activation GO:0042110 289 0.039
positive regulation of nervous system development GO:0051962 221 0.039
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.039
erk1 and erk2 cascade GO:0070371 77 0.038
Human Rat
positive regulation of protein phosphorylation GO:0001934 242 0.038
Human
second messenger mediated signaling GO:0019932 73 0.038
b cell activation GO:0042113 161 0.038
posttranscriptional regulation of gene expression GO:0010608 155 0.037
response to extracellular stimulus GO:0009991 127 0.037
Yeast Fly
regulation of actin filament based process GO:0032970 99 0.037
Human
protein localization to mitochondrion GO:0070585 15 0.037
protein polyubiquitination GO:0000209 33 0.036
multi organism behavior GO:0051705 62 0.036
Rat
regulation of organelle organization GO:0033043 289 0.036
Human
regulation of peptidyl serine phosphorylation GO:0033135 39 0.034
striated muscle myosin thick filament assembly GO:0071688 1 0.034
ubiquitin dependent protein catabolic process GO:0006511 129 0.034
skin development GO:0043588 220 0.033
regulation of response to wounding GO:1903034 189 0.033
Human
macromolecule catabolic process GO:0009057 281 0.033
response to organonitrogen compound GO:0010243 246 0.033
regulation of secretion by cell GO:1903530 249 0.033
Mouse
mitochondrion organization GO:0007005 134 0.033
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.032
peptidyl serine autophosphorylation GO:0036289 1 0.032
single organism cell adhesion GO:0098602 156 0.032
gonad development GO:0008406 141 0.031
Worm
rhythmic process GO:0048511 174 0.031
myosin filament organization GO:0031033 3 0.031
positive regulation of protein ubiquitination GO:0031398 27 0.031
regulation of erk1 and erk2 cascade GO:0070372 71 0.031
Human Rat
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.030
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.030
Human Yeast Worm
positive regulation of cell development GO:0010720 237 0.030
Fly
gene silencing GO:0016458 38 0.030
cellular macromolecule catabolic process GO:0044265 206 0.030
cellular response to abiotic stimulus GO:0071214 56 0.029
actin cytoskeleton organization GO:0030036 220 0.029
Human Mouse
positive regulation of cell projection organization GO:0031346 95 0.029
Human
dephosphorylation GO:0016311 129 0.029
leukocyte differentiation GO:0002521 342 0.028
response to inorganic substance GO:0010035 96 0.028
epidermal growth factor receptor signaling pathway GO:0007173 28 0.028
Worm
ovulation cycle GO:0042698 59 0.028
adiponectin activated signaling pathway GO:0033211 4 0.027
cell growth GO:0016049 130 0.027
Yeast Fly
striated muscle tissue development GO:0014706 293 0.027
Mouse
segmentation GO:0035282 93 0.027
cell maturation GO:0048469 127 0.027
Fly
response to oxygen levels GO:0070482 62 0.027
axonogenesis GO:0007409 274 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
glycoprotein metabolic process GO:0009100 116 0.025
regulation of synaptic plasticity GO:0048167 87 0.025
actomyosin structure organization GO:0031032 56 0.025
peptidyl amino acid modification GO:0018193 336 0.025
intracellular protein transport GO:0006886 204 0.025
Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.025
cellular response to growth factor stimulus GO:0071363 197 0.025
oocyte axis specification GO:0007309 2 0.025
Fly
phospholipid metabolic process GO:0006644 87 0.025
negative regulation of cell motility GO:2000146 61 0.024
Mouse
response to peptide GO:1901652 136 0.024
regulation of cell adhesion GO:0030155 154 0.024
lymphocyte differentiation GO:0030098 242 0.024
cellular response to hormone stimulus GO:0032870 150 0.024
regulation of cellular response to stress GO:0080135 159 0.024
Human Fly
placenta blood vessel development GO:0060674 31 0.024
negative regulation of fibroblast migration GO:0010764 2 0.024
germ cell development GO:0007281 185 0.023
Worm Fly
carbohydrate metabolic process GO:0005975 230 0.023
response to nutrient levels GO:0031667 109 0.023
Yeast Fly
positive regulation of wnt signaling pathway GO:0030177 45 0.023
synaptic transmission GO:0007268 329 0.023
cellular response to extracellular stimulus GO:0031668 81 0.023
Yeast Fly
stem cell differentiation GO:0048863 268 0.022
Fly
protein neddylation GO:0045116 1 0.022
macroautophagy GO:0016236 21 0.022
Fly
regulation of ras protein signal transduction GO:0046578 114 0.022
Human Mouse Rat Worm
single organism nuclear import GO:1902593 95 0.022
Fly
regulation of protein serine threonine kinase activity GO:0071900 157 0.022
Human
oocyte construction GO:0007308 2 0.022
Fly
carbohydrate homeostasis GO:0033500 128 0.022
morphogenesis of a branching epithelium GO:0061138 193 0.022
Mouse
protein localization to organelle GO:0033365 185 0.022
Fly
muscle tissue development GO:0060537 308 0.022
Mouse
response to growth factor GO:0070848 198 0.021
cell matrix adhesion GO:0007160 68 0.021
positive regulation of nucleoside metabolic process GO:0045979 91 0.021
Human Worm
regulation of hydrolase activity GO:0051336 246 0.021
Human Worm
positive regulation of cell adhesion GO:0045785 80 0.021
response to peptide hormone GO:0043434 127 0.021
extrinsic apoptotic signaling pathway GO:0097191 126 0.021
positive regulation of protein kinase activity GO:0045860 144 0.021
Human
female gonad development GO:0008585 71 0.021
protein localization to nucleus GO:0034504 121 0.021
Fly
myofibril assembly GO:0030239 34 0.021
hyperosmotic response GO:0006972 4 0.021
regulation of exocytosis GO:0017157 61 0.021
Mouse
glucose homeostasis GO:0042593 128 0.020
phospholipid biosynthetic process GO:0008654 36 0.020
leukocyte activation involved in immune response GO:0002366 126 0.020
rna interference GO:0016246 2 0.020
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.020
actin filament organization GO:0007015 113 0.020
cellular protein complex assembly GO:0043623 116 0.020
myotube differentiation GO:0014902 105 0.020
positive regulation of transferase activity GO:0051347 167 0.020
Human
establishment of vesicle localization GO:0051650 81 0.019
regulation of cell substrate adhesion GO:0010810 73 0.019
cytokine mediated signaling pathway GO:0019221 115 0.019
rho protein signal transduction GO:0007266 32 0.019
embryonic placenta development GO:0001892 98 0.019
protein localization to plasma membrane GO:0072659 57 0.019
regulation of proteolysis GO:0030162 164 0.019
neurotransmitter secretion GO:0007269 62 0.019
glycoprotein biosynthetic process GO:0009101 89 0.019
blood vessel morphogenesis GO:0048514 285 0.019
regulation of cellular response to growth factor stimulus GO:0090287 82 0.019
homeostasis of number of cells GO:0048872 210 0.019
Fly
regulation of cellular component biogenesis GO:0044087 181 0.018
Human
cell adhesion GO:0007155 329 0.018
response to decreased oxygen levels GO:0036293 59 0.018
mapk cascade GO:0000165 281 0.018
Human Rat Fly
associative learning GO:0008306 61 0.018
Mouse
cellular response to lipid GO:0071396 145 0.018
g protein coupled receptor signaling pathway GO:0007186 243 0.018
Yeast
cardiocyte differentiation GO:0035051 87 0.018
muscle cell differentiation GO:0042692 261 0.018
Mouse
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
Human
mitotic cell cycle process GO:1903047 159 0.017
Human
cellular response to nutrient levels GO:0031669 64 0.017
Yeast Fly
multi multicellular organism process GO:0044706 109 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
glycerophospholipid metabolic process GO:0006650 71 0.017
genitalia development GO:0048806 37 0.017
Worm
glycosyl compound catabolic process GO:1901658 206 0.017
Human Yeast Mouse Worm Fly
female sex differentiation GO:0046660 84 0.017
stem cell development GO:0048864 219 0.017
negative regulation of neuron death GO:1901215 98 0.017
glycerophospholipid biosynthetic process GO:0046474 32 0.017
photoreceptor cell differentiation GO:0046530 52 0.017
Fly
myosin filament assembly GO:0031034 2 0.017
mitotic cell cycle GO:0000278 195 0.017
Human
regulation of neuron projection development GO:0010975 169 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
positive regulation of cell motility GO:2000147 116 0.016
Human Mouse
cellular response to acid chemical GO:0071229 68 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
response to starvation GO:0042594 65 0.016
Fly
amide transport GO:0042886 138 0.016
positive regulation of cell substrate adhesion GO:0010811 47 0.016
neuron migration GO:0001764 122 0.016
detection of abiotic stimulus GO:0009582 60 0.016
regulation of protein localization GO:0032880 231 0.016
Yeast
telencephalon development GO:0021537 186 0.016
spermatid differentiation GO:0048515 115 0.016
retrograde transport endosome to golgi GO:0042147 2 0.016
inflammatory response GO:0006954 244 0.016
mitochondrial transport GO:0006839 36 0.016
response to drug GO:0042493 75 0.016
regulation of defense response GO:0031347 233 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
Human Yeast Mouse Worm Fly
nucleotide metabolic process GO:0009117 332 0.016
Human Yeast Mouse Worm Fly
positive t cell selection GO:0043368 23 0.016
immune effector process GO:0002252 321 0.016
regulation of cell activation GO:0050865 289 0.016
myeloid cell differentiation GO:0030099 233 0.015
response to organic cyclic compound GO:0014070 198 0.015
spermatid development GO:0007286 108 0.015
regulation of transposition GO:0010528 2 0.015
zymogen activation GO:0031638 41 0.015
regulation of response to osmotic stress GO:0047484 3 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
Human Yeast Mouse Worm Fly
negative regulation of protein phosphorylation GO:0001933 126 0.015
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.015
regulation of cell cycle process GO:0010564 160 0.015
Human
regulation of exit from mitosis GO:0007096 1 0.015
forebrain development GO:0030900 302 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.015
positive regulation of organelle organization GO:0010638 128 0.015
Human
morphogenesis of an endothelium GO:0003159 2 0.015
t cell differentiation GO:0030217 174 0.014
regulation of protein complex assembly GO:0043254 83 0.014
regulation of chromosome organization GO:0033044 83 0.014
positive regulation of kinase activity GO:0033674 155 0.014
Human
mitochondrial membrane organization GO:0007006 26 0.014
response to temperature stimulus GO:0009266 55 0.014
reproductive behavior GO:0019098 32 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
Human Yeast Mouse Worm Fly
regulation of myeloid cell differentiation GO:0045637 96 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.014
Human Worm
cell activation involved in immune response GO:0002263 126 0.014
regulation of metal ion transport GO:0010959 106 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
regulation of peptide secretion GO:0002791 77 0.014
response to acid chemical GO:0001101 111 0.014
stem cell maintenance GO:0019827 130 0.014
development of primary sexual characteristics GO:0045137 143 0.014
Worm
regulation of protein kinase activity GO:0045859 232 0.014
Human
learning or memory GO:0007611 148 0.013
Mouse
labyrinthine layer development GO:0060711 49 0.013
activation of adenylate cyclase activity GO:0007190 4 0.013
Yeast
positive regulation of homeostatic process GO:0032846 64 0.013
cellular ion homeostasis GO:0006873 165 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
multicellular organism growth GO:0035264 161 0.013
Fly
regulation of protein catabolic process GO:0042176 108 0.013
muscle system process GO:0003012 141 0.013
positive regulation of neuron projection development GO:0010976 79 0.013
striated muscle contraction GO:0006941 45 0.013
striated muscle cell development GO:0055002 125 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
Human Yeast Mouse Worm Fly
cell type specific apoptotic process GO:0097285 268 0.013
transmembrane transport GO:0055085 412 0.013
midgut development GO:0007494 4 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
negative regulation of cellular catabolic process GO:0031330 47 0.013
Human Fly
regulation of kinase activity GO:0043549 249 0.013
Human
regulation of mitotic cell cycle GO:0007346 126 0.013
Human
regulation of synapse structural plasticity GO:0051823 4 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
Human
tissue homeostasis GO:0001894 115 0.013
protein maturation GO:0051604 176 0.012
notch signaling pathway GO:0007219 71 0.012
fibroblast migration GO:0010761 21 0.012
response to monosaccharide GO:0034284 67 0.012
organ growth GO:0035265 117 0.012
synaptic vesicle transport GO:0048489 57 0.012
peptidyl tyrosine dephosphorylation GO:0035335 23 0.012
cellular response to external stimulus GO:0071496 88 0.012
Yeast Fly
negative regulation of neuron apoptotic process GO:0043524 92 0.012
nitrogen compound transport GO:0071705 271 0.012
positive regulation of cell growth GO:0030307 33 0.012
regulation of translation GO:0006417 71 0.012
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.012
protein import into nucleus GO:0006606 95 0.012
Fly
endothelium development GO:0003158 45 0.012
camera type eye development GO:0043010 266 0.012
development of primary female sexual characteristics GO:0046545 73 0.012
cellular response to starvation GO:0009267 57 0.012
Fly
regulation of glucose import GO:0046324 26 0.012
brain segmentation GO:0035284 3 0.012
translation GO:0006412 93 0.012
fatty acid metabolic process GO:0006631 121 0.012
cd4 positive alpha beta t cell activation GO:0035710 45 0.011
microtubule based process GO:0007017 236 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
Human Worm
cardiac muscle tissue development GO:0048738 130 0.011
exocytosis GO:0006887 121 0.011
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.011
Human Yeast Mouse Worm Fly
circulatory system process GO:0003013 197 0.011
regulation of hormone levels GO:0010817 211 0.011
regulation of muscle tissue development GO:1901861 97 0.011
Mouse
bmp signaling pathway GO:0030509 93 0.011
cardiac chamber development GO:0003205 108 0.011
lipid biosynthetic process GO:0008610 179 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
Human Yeast Mouse Worm Fly
regulation of myeloid leukocyte differentiation GO:0002761 58 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
Human Worm
posttranscriptional gene silencing GO:0016441 10 0.011
pallium development GO:0021543 120 0.011
regulation of cell projection organization GO:0031344 206 0.011
Human Worm
cardiac muscle cell differentiation GO:0055007 69 0.011
leukocyte proliferation GO:0070661 172 0.011
detection of external stimulus GO:0009581 61 0.011
blood circulation GO:0008015 195 0.011
cellular homeostasis GO:0019725 240 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
Human Worm
protein glycosylation GO:0006486 55 0.011
phosphatidylinositol phosphorylation GO:0046854 23 0.011
endothelial cell migration GO:0043542 44 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
regulation of synaptic vesicle transport GO:1902803 13 0.011
positive regulation of peptidase activity GO:0010952 49 0.011
epithelial cell migration GO:0010631 63 0.010
Fly
digestive system development GO:0055123 200 0.010
Fly
muscle contraction GO:0006936 101 0.010
circadian rhythm GO:0007623 114 0.010
multicellular organismal reproductive behavior GO:0033057 23 0.010
epidermis development GO:0008544 187 0.010
positive regulation of cell death GO:0010942 224 0.010
epithelial cell proliferation GO:0050673 174 0.010
Human
somite development GO:0061053 81 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
insulin secretion GO:0030073 89 0.010
hormone secretion GO:0046879 128 0.010
peptide secretion GO:0002790 114 0.010
detection of stimulus GO:0051606 84 0.010

Hras1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.084
disease of anatomical entity DOID:7 0 0.084
cardiovascular system disease DOID:1287 0 0.084
myopathy DOID:423 0 0.054
muscular disease DOID:0080000 0 0.054
cardiomyopathy DOID:0050700 0 0.054
musculoskeletal system disease DOID:17 0 0.054
muscle tissue disease DOID:66 0 0.054
dilated cardiomyopathy DOID:12930 0 0.031
intrinsic cardiomyopathy DOID:0060036 0 0.031