Mus musculus

0 known processes

Mkln1

muskelin 1, intracellular mediator containing kelch motifs

(Aliases: AU015903,BB154892,A130067F06Rik)

Mkln1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.109
regulation of protein localization GO:0032880 231 0.066
transmembrane transport GO:0055085 412 0.062
regulation of cellular ketone metabolic process GO:0010565 66 0.062
cellular amine metabolic process GO:0044106 44 0.061
negative regulation of protein metabolic process GO:0051248 282 0.058
organic hydroxy compound metabolic process GO:1901615 203 0.051
lipid localization GO:0010876 126 0.048
apoptotic signaling pathway GO:0097190 306 0.047
regulation of protein serine threonine kinase activity GO:0071900 157 0.047
heterocycle catabolic process GO:0046700 280 0.045
cellular ketone metabolic process GO:0042180 84 0.045
response to organonitrogen compound GO:0010243 246 0.045
intracellular protein transport GO:0006886 204 0.045
regulation of mapk cascade GO:0043408 248 0.045
amine metabolic process GO:0009308 45 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
nuclear import GO:0051170 95 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.042
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
cytoplasmic transport GO:0016482 234 0.041
positive regulation of transferase activity GO:0051347 167 0.041
cellular lipid metabolic process GO:0044255 323 0.039
organic anion transport GO:0015711 137 0.039
protein modification by small protein conjugation or removal GO:0070647 207 0.039
positive regulation of protein modification process GO:0031401 299 0.038
cation transport GO:0006812 399 0.038
response to radiation GO:0009314 165 0.038
purine nucleotide metabolic process GO:0006163 302 0.037
cellular nitrogen compound catabolic process GO:0044270 280 0.037
microtubule based process GO:0007017 236 0.037
response to lipopolysaccharide GO:0032496 128 0.037
protein targeting GO:0006605 143 0.036
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.036
regulation of transferase activity GO:0051338 263 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
ribose phosphate metabolic process GO:0019693 291 0.035
ribonucleotide metabolic process GO:0009259 291 0.035
homeostasis of number of cells GO:0048872 210 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.035
positive regulation of protein phosphorylation GO:0001934 242 0.035
organelle localization GO:0051640 179 0.034
negative regulation of molecular function GO:0044092 258 0.034
negative regulation of phosphorylation GO:0042326 166 0.033
ubiquitin dependent protein catabolic process GO:0006511 129 0.033
negative regulation of cellular amine metabolic process GO:0033239 1 0.033
cellular response to lipid GO:0071396 145 0.033
smoothened signaling pathway GO:0007224 105 0.032
regulation of cell activation GO:0050865 289 0.032
muscle cell differentiation GO:0042692 261 0.031
multicellular organism growth GO:0035264 161 0.031
response to peptide hormone GO:0043434 127 0.031
peptidyl amino acid modification GO:0018193 336 0.031
anion transport GO:0006820 177 0.031
ion transmembrane transport GO:0034220 361 0.031
telencephalon development GO:0021537 186 0.031
retina development in camera type eye GO:0060041 119 0.031
anatomical structure homeostasis GO:0060249 145 0.030
response to molecule of bacterial origin GO:0002237 143 0.030
organic cyclic compound catabolic process GO:1901361 295 0.030
protein import into nucleus GO:0006606 95 0.030
mapk cascade GO:0000165 281 0.030
response to insulin GO:0032868 100 0.030
lipid transport GO:0006869 98 0.030
organic acid transport GO:0015849 101 0.030
response to light stimulus GO:0009416 135 0.029
regulation of protein kinase activity GO:0045859 232 0.029
locomotory behavior GO:0007626 195 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.028
camera type eye development GO:0043010 266 0.028
regulation of kinase activity GO:0043549 249 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
protein import GO:0017038 101 0.028
multicellular organismal homeostasis GO:0048871 164 0.028
maintenance of location GO:0051235 89 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.028
nucleoside catabolic process GO:0009164 206 0.028
cell adhesion GO:0007155 329 0.028
response to organic cyclic compound GO:0014070 198 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
ras protein signal transduction GO:0007265 77 0.028
blood circulation GO:0008015 195 0.028
regulation of protein transport GO:0051223 163 0.027
cation homeostasis GO:0055080 212 0.027
regulation of apoptotic signaling pathway GO:2001233 197 0.026
cognition GO:0050890 149 0.026
nitrogen compound transport GO:0071705 271 0.026
skeletal system development GO:0001501 356 0.026
negative regulation of protein modification process GO:0031400 163 0.026
establishment of protein localization to organelle GO:0072594 118 0.025
adult behavior GO:0030534 135 0.025
single organism nuclear import GO:1902593 95 0.025
carboxylic acid biosynthetic process GO:0046394 86 0.025
fat cell differentiation GO:0045444 160 0.025
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.025
regulation of mitotic cell cycle GO:0007346 126 0.025
organophosphate catabolic process GO:0046434 232 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
organic hydroxy compound transport GO:0015850 93 0.025
wnt signaling pathway GO:0016055 188 0.025
protein localization to organelle GO:0033365 185 0.025
regulation of secretion GO:0051046 274 0.025
small gtpase mediated signal transduction GO:0007264 97 0.024
cellular response to organonitrogen compound GO:0071417 145 0.024
axonogenesis GO:0007409 274 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
organelle fission GO:0048285 170 0.024
cellular metal ion homeostasis GO:0006875 151 0.024
glycosyl compound catabolic process GO:1901658 206 0.024
regulation of body fluid levels GO:0050878 162 0.024
establishment of organelle localization GO:0051656 122 0.024
response to peptide GO:1901652 136 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.024
nucleoside metabolic process GO:0009116 246 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
regulation of metal ion transport GO:0010959 106 0.024
myeloid cell differentiation GO:0030099 233 0.024
aromatic compound catabolic process GO:0019439 286 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
carboxylic acid transport GO:0046942 100 0.023
protein maturation GO:0051604 176 0.023
forebrain development GO:0030900 302 0.023
positive regulation of mapk cascade GO:0043410 170 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
regulation of cell migration GO:0030334 219 0.023
nucleocytoplasmic transport GO:0006913 139 0.023
regulation of stress activated mapk cascade GO:0032872 69 0.023
epithelial cell proliferation GO:0050673 174 0.023
cellular homeostasis GO:0019725 240 0.023
positive regulation of cell death GO:0010942 224 0.023
t cell activation GO:0042110 289 0.023
nuclear division GO:0000280 158 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.022
regulation of proteolysis GO:0030162 164 0.022
defense response to other organism GO:0098542 197 0.022
t cell differentiation GO:0030217 174 0.022
microtubule cytoskeleton organization GO:0000226 157 0.022
protein catabolic process GO:0030163 221 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
nucleotide metabolic process GO:0009117 332 0.022
purine containing compound metabolic process GO:0072521 311 0.021
chromatin organization GO:0006325 206 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
regulation of cellular response to stress GO:0080135 159 0.021
stem cell differentiation GO:0048863 268 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
plasma membrane organization GO:0007009 90 0.021
stem cell development GO:0048864 219 0.021
leukocyte activation involved in immune response GO:0002366 126 0.021
regulation of establishment of protein localization GO:0070201 181 0.021
modification dependent protein catabolic process GO:0019941 133 0.021
cellular response to dna damage stimulus GO:0006974 207 0.021
cellular response to biotic stimulus GO:0071216 92 0.021
protein processing GO:0016485 163 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
defense response to bacterium GO:0042742 119 0.021
covalent chromatin modification GO:0016569 163 0.021
modification dependent macromolecule catabolic process GO:0043632 133 0.021
sequestering of calcium ion GO:0051208 18 0.021
macromolecule catabolic process GO:0009057 281 0.020
blood vessel morphogenesis GO:0048514 285 0.020
alpha beta t cell activation GO:0046631 91 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
calcium ion homeostasis GO:0055074 127 0.020
compound eye development GO:0048749 1 0.020
cellular divalent inorganic cation homeostasis GO:0072503 127 0.020
gtp metabolic process GO:0046039 144 0.020
cellular ion homeostasis GO:0006873 165 0.020
regulation of hydrolase activity GO:0051336 246 0.020
cellular response to hormone stimulus GO:0032870 150 0.020
positive regulation of cellular catabolic process GO:0031331 148 0.020
protein ubiquitination GO:0016567 171 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
canonical wnt signaling pathway GO:0060070 130 0.020
mitotic cell cycle process GO:1903047 159 0.020
transmission of nerve impulse GO:0019226 76 0.020
calcium ion transport GO:0006816 159 0.019
negative regulation of protein phosphorylation GO:0001933 126 0.019
regulation of wnt signaling pathway GO:0030111 123 0.019
protein localization to nucleus GO:0034504 121 0.019
cell growth GO:0016049 130 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
sequestering of metal ion GO:0051238 19 0.019
muscle tissue development GO:0060537 308 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
stem cell proliferation GO:0072089 117 0.019
ossification GO:0001503 216 0.019
purine nucleoside catabolic process GO:0006152 205 0.019
endomembrane system organization GO:0010256 147 0.019
negative regulation of protein processing GO:0010955 79 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
regulation of cell projection organization GO:0031344 206 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
cell division GO:0051301 120 0.018
metal ion homeostasis GO:0055065 189 0.018
regulation of neuron differentiation GO:0045664 281 0.018
regulation of homeostatic process GO:0032844 182 0.018
learning or memory GO:0007611 148 0.018
sensory perception GO:0007600 245 0.018
regulation of intracellular transport GO:0032386 159 0.018
cellular calcium ion homeostasis GO:0006874 119 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
regulation of vesicle mediated transport GO:0060627 139 0.018
regulation of cell motility GO:2000145 236 0.018
histone modification GO:0016570 159 0.018
immune effector process GO:0002252 321 0.018
tissue homeostasis GO:0001894 115 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
mitotic cell cycle GO:0000278 195 0.018
positive regulation of intracellular transport GO:0032388 70 0.018
cell activation involved in immune response GO:0002263 126 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
oxidation reduction process GO:0055114 342 0.017
regulation of hormone levels GO:0010817 211 0.017
chemotaxis GO:0006935 247 0.017
glycoprotein metabolic process GO:0009100 116 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.017
organic acid biosynthetic process GO:0016053 86 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
sensory organ morphogenesis GO:0090596 242 0.017
regulation of map kinase activity GO:0043405 120 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
regulation of protein import into nucleus GO:0042306 52 0.016
positive regulation of kinase activity GO:0033674 155 0.016
cation transmembrane transport GO:0098655 266 0.016
regulation of organelle organization GO:0033043 289 0.016
cellular response to lipopolysaccharide GO:0071222 77 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
innate immune response GO:0045087 157 0.016
lymphocyte activation involved in immune response GO:0002285 93 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
cellular response to insulin stimulus GO:0032869 78 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
mitochondrion organization GO:0007005 134 0.016
cellular response to peptide hormone stimulus GO:0071375 92 0.016
positive regulation of cell activation GO:0050867 158 0.016
blood coagulation GO:0007596 76 0.016
regulation of intracellular protein transport GO:0033157 82 0.016
response to inorganic substance GO:0010035 96 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.016
leukocyte migration GO:0050900 124 0.016
reactive oxygen species metabolic process GO:0072593 84 0.015
purine containing compound catabolic process GO:0072523 213 0.015
membrane organization GO:0061024 245 0.015
negative regulation of immune system process GO:0002683 209 0.015
leukocyte differentiation GO:0002521 342 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
neuron death GO:0070997 154 0.015
regulation of secretion by cell GO:1903530 249 0.015
regulation of protein maturation GO:1903317 96 0.015
regulation of t cell activation GO:0050863 170 0.015
regulation of voltage gated calcium channel activity GO:1901385 4 0.015
cell type specific apoptotic process GO:0097285 268 0.015
meiotic cell cycle GO:0051321 122 0.015
cellular response to molecule of bacterial origin GO:0071219 83 0.015
regulation of membrane potential GO:0042391 192 0.015
regulation of transporter activity GO:0032409 57 0.015
cytokine production GO:0001816 319 0.015
lymphocyte differentiation GO:0030098 242 0.014
neuronal action potential GO:0019228 54 0.014
cellular chemical homeostasis GO:0055082 215 0.014
chromatin modification GO:0016568 187 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
nuclear transport GO:0051169 139 0.014
regulation of cytokine production GO:0001817 266 0.014
metencephalon development GO:0022037 89 0.014
regulation of myeloid cell differentiation GO:0045637 96 0.014
associative learning GO:0008306 61 0.014
immune response regulating signaling pathway GO:0002764 125 0.014
transition metal ion homeostasis GO:0055076 54 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
response to temperature stimulus GO:0009266 55 0.014
cell substrate adhesion GO:0031589 130 0.014
regulation of cell cycle process GO:0010564 160 0.014
adult locomotory behavior GO:0008344 91 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
organelle assembly GO:0070925 177 0.013
fatty acid metabolic process GO:0006631 121 0.013
amino acid transport GO:0006865 61 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
lymphocyte proliferation GO:0046651 164 0.013
response to growth factor GO:0070848 198 0.013
multicellular organismal signaling GO:0035637 91 0.013
wound healing GO:0042060 157 0.013
cellular response to peptide GO:1901653 92 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
endocytosis GO:0006897 168 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
cellular response to external stimulus GO:0071496 88 0.013
stem cell maintenance GO:0019827 130 0.013
regulation of t cell differentiation GO:0045580 83 0.013
regulation of nucleocytoplasmic transport GO:0046822 73 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
regulation of cell cycle GO:0051726 281 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
regulation of neuron death GO:1901214 134 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
macromolecule methylation GO:0043414 120 0.013
lipid biosynthetic process GO:0008610 179 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
action potential GO:0001508 78 0.013
small molecule biosynthetic process GO:0044283 132 0.013
positive regulation of hydrolase activity GO:0051345 148 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
regulation of ion transport GO:0043269 215 0.012
monocarboxylic acid biosynthetic process GO:0072330 61 0.012
hindbrain development GO:0030902 128 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
regulation of multi organism process GO:0043900 111 0.012
carbohydrate metabolic process GO:0005975 230 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
stress activated protein kinase signaling cascade GO:0031098 81 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
fertilization GO:0009566 127 0.012
angiogenesis GO:0001525 201 0.012
divalent metal ion transport GO:0070838 172 0.012
cell chemotaxis GO:0060326 81 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
striated muscle tissue development GO:0014706 293 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
single organism cell adhesion GO:0098602 156 0.012
positive regulation of cytokine production GO:0001819 174 0.012
positive regulation of stress activated mapk cascade GO:0032874 48 0.012
cellular response to amino acid stimulus GO:0071230 29 0.012
negative regulation of nervous system development GO:0051961 156 0.012
amide transport GO:0042886 138 0.012
mitotic nuclear division GO:0007067 48 0.012
male gamete generation GO:0048232 285 0.012
regulation of ion transmembrane transporter activity GO:0032412 54 0.011
negative regulation of cell development GO:0010721 169 0.011
gtp catabolic process GO:0006184 143 0.011
circadian regulation of gene expression GO:0032922 48 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
glial cell differentiation GO:0010001 131 0.011
myeloid cell homeostasis GO:0002262 114 0.011
regulation of binding GO:0051098 111 0.011
asymmetric stem cell division GO:0098722 3 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
ameboidal type cell migration GO:0001667 128 0.011
mesenchyme development GO:0060485 152 0.011
meiotic cell cycle process GO:1903046 77 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.011
spermatogenesis GO:0007283 284 0.011
circulatory system process GO:0003013 197 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
negative regulation of t helper 2 cell differentiation GO:0045629 4 0.011
dna recombination GO:0006310 92 0.011
leukocyte apoptotic process GO:0071887 71 0.011
regulation of protein catabolic process GO:0042176 108 0.011
development of primary sexual characteristics GO:0045137 143 0.011
neural tube development GO:0021915 160 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
nucleotide catabolic process GO:0009166 217 0.011
regulation of protein processing GO:0070613 96 0.011
peptidyl serine modification GO:0018209 83 0.011
positive regulation of cell motility GO:2000147 116 0.011
regulation of transmembrane transport GO:0034762 128 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
glycerolipid metabolic process GO:0046486 122 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
positive regulation of cell development GO:0010720 237 0.011
single fertilization GO:0007338 82 0.011
leukocyte proliferation GO:0070661 172 0.011
insulin receptor signaling pathway GO:0008286 49 0.011
regulation of alpha beta t cell activation GO:0046634 53 0.011
dna repair GO:0006281 107 0.010
positive regulation of intracellular protein transport GO:0090316 42 0.010
alcohol metabolic process GO:0006066 116 0.010
positive regulation of protein transport GO:0051222 93 0.010
methylation GO:0032259 134 0.010
gastrulation GO:0007369 116 0.010
sodium ion transport GO:0006814 73 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.010
peptide hormone secretion GO:0030072 109 0.010
adaptive immune response GO:0002250 155 0.010
cellularization GO:0007349 1 0.010
regulation of feeding behavior GO:0060259 3 0.010
rna interference GO:0016246 2 0.010
inflammatory response GO:0006954 244 0.010
dna metabolic process GO:0006259 303 0.010

Mkln1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.025
cancer DOID:162 0 0.025
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
organ system cancer DOID:0050686 0 0.021
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.018
central nervous system disease DOID:331 0 0.015
immune system disease DOID:2914 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
sensory system disease DOID:0050155 0 0.011
neurodegenerative disease DOID:1289 0 0.011