Mus musculus

0 known processes

Mkln1

muskelin 1, intracellular mediator containing kelch motifs

(Aliases: AU015903,BB154892,A130067F06Rik)

Mkln1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.109
regulation of protein localization GO:0032880 231 0.066
transmembrane transport GO:0055085 412 0.062
regulation of cellular ketone metabolic process GO:0010565 66 0.062
cellular amine metabolic process GO:0044106 44 0.061
negative regulation of protein metabolic process GO:0051248 282 0.058
organic hydroxy compound metabolic process GO:1901615 203 0.051
lipid localization GO:0010876 126 0.048
apoptotic signaling pathway GO:0097190 306 0.047
regulation of protein serine threonine kinase activity GO:0071900 157 0.047
heterocycle catabolic process GO:0046700 280 0.045
cellular ketone metabolic process GO:0042180 84 0.045
response to organonitrogen compound GO:0010243 246 0.045
intracellular protein transport GO:0006886 204 0.045
regulation of mapk cascade GO:0043408 248 0.045
amine metabolic process GO:0009308 45 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
nuclear import GO:0051170 95 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.042
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
cytoplasmic transport GO:0016482 234 0.041
positive regulation of transferase activity GO:0051347 167 0.041
cellular lipid metabolic process GO:0044255 323 0.039
organic anion transport GO:0015711 137 0.039
protein modification by small protein conjugation or removal GO:0070647 207 0.039
positive regulation of protein modification process GO:0031401 299 0.038
cation transport GO:0006812 399 0.038
response to radiation GO:0009314 165 0.038
purine nucleotide metabolic process GO:0006163 302 0.037
cellular nitrogen compound catabolic process GO:0044270 280 0.037
microtubule based process GO:0007017 236 0.037
response to lipopolysaccharide GO:0032496 128 0.037
protein targeting GO:0006605 143 0.036
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.036
regulation of transferase activity GO:0051338 263 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
ribose phosphate metabolic process GO:0019693 291 0.035
ribonucleotide metabolic process GO:0009259 291 0.035
homeostasis of number of cells GO:0048872 210 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.035
positive regulation of protein phosphorylation GO:0001934 242 0.035
organelle localization GO:0051640 179 0.034
negative regulation of molecular function GO:0044092 258 0.034
negative regulation of phosphorylation GO:0042326 166 0.033
ubiquitin dependent protein catabolic process GO:0006511 129 0.033
negative regulation of cellular amine metabolic process GO:0033239 1 0.033
cellular response to lipid GO:0071396 145 0.033
smoothened signaling pathway GO:0007224 105 0.032
regulation of cell activation GO:0050865 289 0.032
muscle cell differentiation GO:0042692 261 0.031
multicellular organism growth GO:0035264 161 0.031
response to peptide hormone GO:0043434 127 0.031
peptidyl amino acid modification GO:0018193 336 0.031
anion transport GO:0006820 177 0.031
ion transmembrane transport GO:0034220 361 0.031
telencephalon development GO:0021537 186 0.031
retina development in camera type eye GO:0060041 119 0.031
anatomical structure homeostasis GO:0060249 145 0.030
response to molecule of bacterial origin GO:0002237 143 0.030
organic cyclic compound catabolic process GO:1901361 295 0.030
protein import into nucleus GO:0006606 95 0.030
mapk cascade GO:0000165 281 0.030
response to insulin GO:0032868 100 0.030
lipid transport GO:0006869 98 0.030
organic acid transport GO:0015849 101 0.030
response to light stimulus GO:0009416 135 0.029
regulation of protein kinase activity GO:0045859 232 0.029
locomotory behavior GO:0007626 195 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.028
camera type eye development GO:0043010 266 0.028
regulation of kinase activity GO:0043549 249 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
protein import GO:0017038 101 0.028
multicellular organismal homeostasis GO:0048871 164 0.028
maintenance of location GO:0051235 89 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.028
nucleoside catabolic process GO:0009164 206 0.028
cell adhesion GO:0007155 329 0.028
response to organic cyclic compound GO:0014070 198 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
ras protein signal transduction GO:0007265 77 0.028
blood circulation GO:0008015 195 0.028
regulation of protein transport GO:0051223 163 0.027
cation homeostasis GO:0055080 212 0.027
regulation of apoptotic signaling pathway GO:2001233 197 0.026
cognition GO:0050890 149 0.026
nitrogen compound transport GO:0071705 271 0.026
skeletal system development GO:0001501 356 0.026
negative regulation of protein modification process GO:0031400 163 0.026
establishment of protein localization to organelle GO:0072594 118 0.025
adult behavior GO:0030534 135 0.025
single organism nuclear import GO:1902593 95 0.025
carboxylic acid biosynthetic process GO:0046394 86 0.025
fat cell differentiation GO:0045444 160 0.025
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.025
regulation of mitotic cell cycle GO:0007346 126 0.025
organophosphate catabolic process GO:0046434 232 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
organic hydroxy compound transport GO:0015850 93 0.025
wnt signaling pathway GO:0016055 188 0.025
protein localization to organelle GO:0033365 185 0.025
regulation of secretion GO:0051046 274 0.025
small gtpase mediated signal transduction GO:0007264 97 0.024
cellular response to organonitrogen compound GO:0071417 145 0.024
axonogenesis GO:0007409 274 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
organelle fission GO:0048285 170 0.024
cellular metal ion homeostasis GO:0006875 151 0.024
glycosyl compound catabolic process GO:1901658 206 0.024
regulation of body fluid levels GO:0050878 162 0.024
establishment of organelle localization GO:0051656 122 0.024
response to peptide GO:1901652 136 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.024
nucleoside metabolic process GO:0009116 246 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
regulation of metal ion transport GO:0010959 106 0.024
myeloid cell differentiation GO:0030099 233 0.024
aromatic compound catabolic process GO:0019439 286 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
carboxylic acid transport GO:0046942 100 0.023
protein maturation GO:0051604 176 0.023
forebrain development GO:0030900 302 0.023
positive regulation of mapk cascade GO:0043410 170 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
regulation of cell migration GO:0030334 219 0.023
nucleocytoplasmic transport GO:0006913 139 0.023
regulation of stress activated mapk cascade GO:0032872 69 0.023
epithelial cell proliferation GO:0050673 174 0.023
cellular homeostasis GO:0019725 240 0.023
positive regulation of cell death GO:0010942 224 0.023
t cell activation GO:0042110 289 0.023
nuclear division GO:0000280 158 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.022
regulation of proteolysis GO:0030162 164 0.022
defense response to other organism GO:0098542 197 0.022
t cell differentiation GO:0030217 174 0.022
microtubule cytoskeleton organization GO:0000226 157 0.022
protein catabolic process GO:0030163 221 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
nucleotide metabolic process GO:0009117 332 0.022
purine containing compound metabolic process GO:0072521 311 0.021
chromatin organization GO:0006325 206 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
regulation of cellular response to stress GO:0080135 159 0.021
stem cell differentiation GO:0048863 268 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
plasma membrane organization GO:0007009 90 0.021
stem cell development GO:0048864 219 0.021
leukocyte activation involved in immune response GO:0002366 126 0.021
regulation of establishment of protein localization GO:0070201 181 0.021
modification dependent protein catabolic process GO:0019941 133 0.021
cellular response to dna damage stimulus GO:0006974 207 0.021
cellular response to biotic stimulus GO:0071216 92 0.021
protein processing GO:0016485 163 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
defense response to bacterium GO:0042742 119 0.021
covalent chromatin modification GO:0016569 163 0.021
modification dependent macromolecule catabolic process GO:0043632 133 0.021
sequestering of calcium ion GO:0051208 18 0.021
macromolecule catabolic process GO:0009057 281 0.020
blood vessel morphogenesis GO:0048514 285 0.020
alpha beta t cell activation GO:0046631 91 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
calcium ion homeostasis GO:0055074 127 0.020
compound eye development GO:0048749 1 0.020
cellular divalent inorganic cation homeostasis GO:0072503 127 0.020
gtp metabolic process GO:0046039 144 0.020
cellular ion homeostasis GO:0006873 165 0.020
regulation of hydrolase activity GO:0051336 246 0.020
cellular response to hormone stimulus GO:0032870 150 0.020
positive regulation of cellular catabolic process GO:0031331 148 0.020
protein ubiquitination GO:0016567 171 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
canonical wnt signaling pathway GO:0060070 130 0.020
mitotic cell cycle process GO:1903047 159 0.020
transmission of nerve impulse GO:0019226 76 0.020
calcium ion transport GO:0006816 159 0.019
negative regulation of protein phosphorylation GO:0001933 126 0.019
regulation of wnt signaling pathway GO:0030111 123 0.019
protein localization to nucleus GO:0034504 121 0.019
cell growth GO:0016049 130 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
sequestering of metal ion GO:0051238 19 0.019
muscle tissue development GO:0060537 308 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
stem cell proliferation GO:0072089 117 0.019
ossification GO:0001503 216 0.019
purine nucleoside catabolic process GO:0006152 205 0.019
endomembrane system organization GO:0010256 147 0.019
negative regulation of protein processing GO:0010955 79 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
regulation of cell projection organization GO:0031344 206 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
cell division GO:0051301 120 0.018
metal ion homeostasis GO:0055065 189 0.018
regulation of neuron differentiation GO:0045664 281 0.018
regulation of homeostatic process GO:0032844 182 0.018
learning or memory GO:0007611 148 0.018
sensory perception GO:0007600 245 0.018
regulation of intracellular transport GO:0032386 159 0.018
cellular calcium ion homeostasis GO:0006874 119 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
regulation of vesicle mediated transport GO:0060627 139 0.018
regulation of cell motility GO:2000145 236 0.018
histone modification GO:0016570 159 0.018
immune effector process GO:0002252 321 0.018
tissue homeostasis GO:0001894 115 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
mitotic cell cycle GO:0000278 195 0.018
positive regulation of intracellular transport GO:0032388 70 0.018
cell activation involved in immune response GO:0002263 126 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
oxidation reduction process GO:0055114 342 0.017
regulation of hormone levels GO:0010817 211 0.017
chemotaxis GO:0006935 247 0.017
glycoprotein metabolic process GO:0009100 116 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.017
organic acid biosynthetic process GO:0016053 86 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
sensory organ morphogenesis GO:0090596 242 0.017
regulation of map kinase activity GO:0043405 120 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
regulation of protein import into nucleus GO:0042306 52 0.016
positive regulation of kinase activity GO:0033674 155 0.016
cation transmembrane transport GO:0098655 266 0.016
regulation of organelle organization GO:0033043 289 0.016
cellular response to lipopolysaccharide GO:0071222 77 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
innate immune response GO:0045087 157 0.016
lymphocyte activation involved in immune response GO:0002285 93 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
cellular response to insulin stimulus GO:0032869 78 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
mitochondrion organization GO:0007005 134 0.016
cellular response to peptide hormone stimulus GO:0071375 92 0.016
positive regulation of cell activation GO:0050867 158 0.016
blood coagulation GO:0007596 76 0.016
regulation of intracellular protein transport GO:0033157 82 0.016
response to inorganic substance GO:0010035 96 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.016
leukocyte migration GO:0050900 124 0.016
reactive oxygen species metabolic process GO:0072593 84 0.015
purine containing compound catabolic process GO:0072523 213 0.015
membrane organization GO:0061024 245 0.015
negative regulation of immune system process GO:0002683 209 0.015
leukocyte differentiation GO:0002521 342 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
neuron death GO:0070997 154 0.015
regulation of secretion by cell GO:1903530 249 0.015
regulation of protein maturation GO:1903317 96 0.015
regulation of t cell activation GO:0050863 170 0.015
regulation of voltage gated calcium channel activity GO:1901385 4 0.015
cell type specific apoptotic process GO:0097285 268 0.015
meiotic cell cycle GO:0051321 122 0.015
cellular response to molecule of bacterial origin GO:0071219 83 0.015
regulation of membrane potential GO:0042391 192 0.015
regulation of transporter activity GO:0032409 57 0.015
cytokine production GO:0001816 319 0.015
lymphocyte differentiation GO:0030098 242 0.014
neuronal action potential GO:0019228 54 0.014
cellular chemical homeostasis GO:0055082 215 0.014
chromatin modification GO:0016568 187 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
nuclear transport GO:0051169 139 0.014
regulation of cytokine production GO:0001817 266 0.014
metencephalon development GO:0022037 89 0.014
regulation of myeloid cell differentiation GO:0045637 96 0.014
associative learning GO:0008306 61 0.014
immune response regulating signaling pathway GO:0002764 125 0.014
transition metal ion homeostasis GO:0055076 54 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
response to temperature stimulus GO:0009266 55 0.014
cell substrate adhesion GO:0031589 130 0.014
regulation of cell cycle process GO:0010564 160 0.014
adult locomotory behavior GO:0008344 91 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
organelle assembly GO:0070925 177 0.013
fatty acid metabolic process GO:0006631 121 0.013
amino acid transport GO:0006865 61 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
lymphocyte proliferation GO:0046651 164 0.013
response to growth factor GO:0070848 198 0.013
multicellular organismal signaling GO:0035637 91 0.013
wound healing GO:0042060 157 0.013
cellular response to peptide GO:1901653 92 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
endocytosis GO:0006897 168 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
cellular response to external stimulus GO:0071496 88 0.013
stem cell maintenance GO:0019827 130 0.013
regulation of t cell differentiation GO:0045580 83 0.013
regulation of nucleocytoplasmic transport GO:0046822 73 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
regulation of cell cycle GO:0051726 281 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
regulation of neuron death GO:1901214 134 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
macromolecule methylation GO:0043414 120 0.013
lipid biosynthetic process GO:0008610 179 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
action potential GO:0001508 78 0.013
small molecule biosynthetic process GO:0044283 132 0.013
positive regulation of hydrolase activity GO:0051345 148 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
regulation of ion transport GO:0043269 215 0.012
monocarboxylic acid biosynthetic process GO:0072330 61 0.012
hindbrain development GO:0030902 128 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
regulation of multi organism process GO:0043900 111 0.012
carbohydrate metabolic process GO:0005975 230 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
stress activated protein kinase signaling cascade GO:0031098 81 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
fertilization GO:0009566 127 0.012
angiogenesis GO:0001525 201 0.012
divalent metal ion transport GO:0070838 172 0.012
cell chemotaxis GO:0060326 81 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
striated muscle tissue development GO:0014706 293 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
single organism cell adhesion GO:0098602 156 0.012
positive regulation of cytokine production GO:0001819 174 0.012
positive regulation of stress activated mapk cascade GO:0032874 48 0.012
cellular response to amino acid stimulus GO:0071230 29 0.012
negative regulation of nervous system development GO:0051961 156 0.012
amide transport GO:0042886 138 0.012
mitotic nuclear division GO:0007067 48 0.012
male gamete generation GO:0048232 285 0.012
regulation of ion transmembrane transporter activity GO:0032412 54 0.011
negative regulation of cell development GO:0010721 169 0.011
gtp catabolic process GO:0006184 143 0.011
circadian regulation of gene expression GO:0032922 48 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
glial cell differentiation GO:0010001 131 0.011
myeloid cell homeostasis GO:0002262 114 0.011
regulation of binding GO:0051098 111 0.011
asymmetric stem cell division GO:0098722 3 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
ameboidal type cell migration GO:0001667 128 0.011
mesenchyme development GO:0060485 152 0.011
meiotic cell cycle process GO:1903046 77 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.011
spermatogenesis GO:0007283 284 0.011
circulatory system process GO:0003013 197 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
negative regulation of t helper 2 cell differentiation GO:0045629 4 0.011
dna recombination GO:0006310 92 0.011
leukocyte apoptotic process GO:0071887 71 0.011
regulation of protein catabolic process GO:0042176 108 0.011
development of primary sexual characteristics GO:0045137 143 0.011
neural tube development GO:0021915 160 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
nucleotide catabolic process GO:0009166 217 0.011
regulation of protein processing GO:0070613 96 0.011
peptidyl serine modification GO:0018209 83 0.011
positive regulation of cell motility GO:2000147 116 0.011
regulation of transmembrane transport GO:0034762 128 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
glycerolipid metabolic process GO:0046486 122 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
positive regulation of cell development GO:0010720 237 0.011
single fertilization GO:0007338 82 0.011
leukocyte proliferation GO:0070661 172 0.011
insulin receptor signaling pathway GO:0008286 49 0.011
regulation of alpha beta t cell activation GO:0046634 53 0.011
dna repair GO:0006281 107 0.010
positive regulation of intracellular protein transport GO:0090316 42 0.010
alcohol metabolic process GO:0006066 116 0.010
positive regulation of protein transport GO:0051222 93 0.010
methylation GO:0032259 134 0.010
gastrulation GO:0007369 116 0.010
sodium ion transport GO:0006814 73 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.010
peptide hormone secretion GO:0030072 109 0.010
adaptive immune response GO:0002250 155 0.010
cellularization GO:0007349 1 0.010
regulation of feeding behavior GO:0060259 3 0.010
rna interference GO:0016246 2 0.010
inflammatory response GO:0006954 244 0.010
dna metabolic process GO:0006259 303 0.010

Mkln1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
organ system cancer DOID:0050686 0 0.021
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.018
central nervous system disease DOID:331 0 0.015
immune system disease DOID:2914 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
sensory system disease DOID:0050155 0 0.011
neurodegenerative disease DOID:1289 0 0.011