Mus musculus

0 known processes

Smg6

Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)

(Aliases: AU041178,MGC7717,AI317223)

Smg6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 45 0.064
cilium assembly GO:0042384 81 0.062
regulation of cellular ketone metabolic process GO:0010565 66 0.062
covalent chromatin modification GO:0016569 163 0.062
regulation of cellular amine metabolic process GO:0033238 20 0.061
regulation of cellular component biogenesis GO:0044087 181 0.056
exocytosis GO:0006887 121 0.054
cellular amine metabolic process GO:0044106 44 0.054
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
cellular component assembly involved in morphogenesis GO:0010927 139 0.051
peptidyl amino acid modification GO:0018193 336 0.050
regulation of organelle organization GO:0033043 289 0.047
cellular amino acid metabolic process GO:0006520 103 0.046
cilium morphogenesis GO:0060271 102 0.044
spermatogenesis GO:0007283 284 0.042
cellular ketone metabolic process GO:0042180 84 0.041
histone methylation GO:0016571 71 0.041
chromatin organization GO:0006325 206 0.041
dna metabolic process GO:0006259 303 0.040
histone modification GO:0016570 159 0.040
ras protein signal transduction GO:0007265 77 0.039
actin cytoskeleton organization GO:0030036 220 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
male gamete generation GO:0048232 285 0.035
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
macromolecule methylation GO:0043414 120 0.035
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.035
methylation GO:0032259 134 0.034
regulation of cell projection organization GO:0031344 206 0.034
organelle assembly GO:0070925 177 0.033
regulation of membrane potential GO:0042391 192 0.032
regionalization GO:0003002 337 0.031
cellular response to dna damage stimulus GO:0006974 207 0.031
nucleoside triphosphate metabolic process GO:0009141 230 0.031
urogenital system development GO:0001655 261 0.030
small gtpase mediated signal transduction GO:0007264 97 0.030
wnt signaling pathway GO:0016055 188 0.030
regulation of neuron differentiation GO:0045664 281 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.029
renal system development GO:0072001 225 0.029
protein alkylation GO:0008213 81 0.029
multicellular organism growth GO:0035264 161 0.028
leukocyte differentiation GO:0002521 342 0.028
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
cytoplasmic transport GO:0016482 234 0.027
actin filament organization GO:0007015 113 0.026
axonogenesis GO:0007409 274 0.025
muscle tissue development GO:0060537 308 0.024
rho protein signal transduction GO:0007266 32 0.024
positive regulation of protein modification process GO:0031401 299 0.024
transmission of nerve impulse GO:0019226 76 0.024
developmental maturation GO:0021700 193 0.024
respiratory system development GO:0060541 190 0.024
regulation of vesicle mediated transport GO:0060627 139 0.023
dna repair GO:0006281 107 0.023
alcohol metabolic process GO:0006066 116 0.023
synaptic transmission GO:0007268 329 0.023
regulation of secretion GO:0051046 274 0.023
regulation of cell cycle GO:0051726 281 0.023
purine containing compound metabolic process GO:0072521 311 0.023
camera type eye development GO:0043010 266 0.022
purine containing compound catabolic process GO:0072523 213 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.022
organelle localization GO:0051640 179 0.022
ribonucleoside catabolic process GO:0042454 206 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
regulation of cytoskeleton organization GO:0051493 122 0.022
organonitrogen compound catabolic process GO:1901565 264 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
cell maturation GO:0048469 127 0.021
stem cell differentiation GO:0048863 268 0.021
embryonic organ morphogenesis GO:0048562 276 0.021
Worm
multicellular organismal signaling GO:0035637 91 0.021
response to organonitrogen compound GO:0010243 246 0.021
response to light stimulus GO:0009416 135 0.021
digestive system development GO:0055123 200 0.021
nucleotide catabolic process GO:0009166 217 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
chromatin modification GO:0016568 187 0.021
ear development GO:0043583 200 0.020
positive regulation of organelle organization GO:0010638 128 0.020
transmembrane transport GO:0055085 412 0.020
regulation of neuron projection development GO:0010975 169 0.020
stem cell development GO:0048864 219 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
regulation of wnt signaling pathway GO:0030111 123 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
cation transmembrane transport GO:0098655 266 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
membrane organization GO:0061024 245 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
Worm
kidney development GO:0001822 213 0.019
positive regulation of cell death GO:0010942 224 0.019
regulation of secretion by cell GO:1903530 249 0.019
regulation of exocytosis GO:0017157 61 0.019
cellular lipid metabolic process GO:0044255 323 0.019
regulation of actin cytoskeleton organization GO:0032956 84 0.019
myeloid cell differentiation GO:0030099 233 0.019
hindbrain development GO:0030902 128 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
regulation of protein localization GO:0032880 231 0.019
germ cell development GO:0007281 185 0.019
heterochromatin organization GO:0070828 4 0.019
action potential GO:0001508 78 0.018
protein localization to organelle GO:0033365 185 0.018
positive regulation of nervous system development GO:0051962 221 0.018
neuronal action potential GO:0019228 54 0.018
digestive tract morphogenesis GO:0048546 147 0.018
cell adhesion GO:0007155 329 0.018
nucleotide metabolic process GO:0009117 332 0.018
divalent inorganic cation transport GO:0072511 178 0.018
regulation of nucleoside metabolic process GO:0009118 130 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
sensory perception of mechanical stimulus GO:0050954 107 0.018
immune effector process GO:0002252 321 0.018
nucleoside catabolic process GO:0009164 206 0.018
maintenance of location GO:0051235 89 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
sequestering of metal ion GO:0051238 19 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
regulation of cellular response to stress GO:0080135 159 0.018
gene silencing GO:0016458 38 0.018
Worm
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
vesicle localization GO:0051648 86 0.017
intracellular protein transport GO:0006886 204 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
cation transport GO:0006812 399 0.017
nitrogen compound transport GO:0071705 271 0.017
cardiac chamber development GO:0003205 108 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
regulation of cell cycle process GO:0010564 160 0.017
gland development GO:0048732 330 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
regulation of actin filament based process GO:0032970 99 0.017
organophosphate catabolic process GO:0046434 232 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
compound eye development GO:0048749 1 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
telencephalon development GO:0021537 186 0.017
metal ion homeostasis GO:0055065 189 0.016
fertilization GO:0009566 127 0.016
ear morphogenesis GO:0042471 118 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
protein methylation GO:0006479 81 0.016
forebrain development GO:0030900 302 0.016
neuron death GO:0070997 154 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
cell type specific apoptotic process GO:0097285 268 0.016
sequestering of calcium ion GO:0051208 18 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
heart morphogenesis GO:0003007 178 0.016
ion transmembrane transport GO:0034220 361 0.016
muscle system process GO:0003012 141 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
endodermal cell fate specification GO:0001714 4 0.016
response to radiation GO:0009314 165 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
regulation of mapk cascade GO:0043408 248 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
sensory perception GO:0007600 245 0.015
regulation of intracellular transport GO:0032386 159 0.015
gliogenesis GO:0042063 141 0.015
response to organic cyclic compound GO:0014070 198 0.015
striated muscle tissue development GO:0014706 293 0.015
sensory perception of sound GO:0007605 97 0.015
apoptotic signaling pathway GO:0097190 306 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
positive regulation of tor signaling GO:0032008 3 0.015
synapse organization GO:0050808 125 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
cardiac chamber morphogenesis GO:0003206 93 0.015
protein localization to nucleus GO:0034504 121 0.015
skin development GO:0043588 220 0.015
positive regulation of cell development GO:0010720 237 0.015
appendage morphogenesis GO:0035107 149 0.015
response to acid chemical GO:0001101 111 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
cellular homeostasis GO:0019725 240 0.015
microtubule based movement GO:0007018 84 0.014
neurotransmitter secretion GO:0007269 62 0.014
regulation of histone methylation GO:0031060 30 0.014
response to growth factor GO:0070848 198 0.014
regulation of transferase activity GO:0051338 263 0.014
nucleoside metabolic process GO:0009116 246 0.014
regulation of ion transport GO:0043269 215 0.014
digestive tract development GO:0048565 190 0.014
oocyte axis specification GO:0007309 2 0.014
cellular protein complex assembly GO:0043623 116 0.014
mitotic cell cycle process GO:1903047 159 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
metencephalon development GO:0022037 89 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
cellular protein catabolic process GO:0044257 155 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
rac protein signal transduction GO:0016601 13 0.013
posttranscriptional gene silencing GO:0016441 10 0.013
Worm
cellular ion homeostasis GO:0006873 165 0.013
establishment of organelle localization GO:0051656 122 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
regulation of chromosome organization GO:0033044 83 0.013
morphogenesis of a branching structure GO:0001763 203 0.013
rna processing GO:0006396 105 0.013
nuclear division GO:0000280 158 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
cellular chemical homeostasis GO:0055082 215 0.013
neurotransmitter transport GO:0006836 76 0.013
regulation of actin polymerization or depolymerization GO:0008064 45 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
actin polymerization or depolymerization GO:0008154 54 0.013
defecation GO:0030421 1 0.013
gastrulation GO:0007369 116 0.013
cochlea development GO:0090102 35 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
sensory system development GO:0048880 3 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
organelle fission GO:0048285 170 0.013
lung development GO:0030324 164 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
nuclear transport GO:0051169 139 0.013
histone lysine methylation GO:0034968 50 0.013
gtp catabolic process GO:0006184 143 0.013
limb morphogenesis GO:0035108 149 0.013
actin filament polymerization GO:0030041 44 0.013
skeletal system development GO:0001501 356 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
lateral inhibition GO:0046331 1 0.012
regulation of gtp catabolic process GO:0033124 113 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
small molecule biosynthetic process GO:0044283 132 0.012
extracellular structure organization GO:0043062 148 0.012
circulatory system process GO:0003013 197 0.012
blood vessel morphogenesis GO:0048514 285 0.012
organic anion transport GO:0015711 137 0.012
wound healing GO:0042060 157 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
cellularization GO:0007349 1 0.012
aromatic compound catabolic process GO:0019439 286 0.012
Worm
retina development in camera type eye GO:0060041 119 0.012
mesodermal cell migration GO:0008078 4 0.012
inner ear morphogenesis GO:0042472 101 0.012
regulation of hydrolase activity GO:0051336 246 0.012
establishment of vesicle localization GO:0051650 81 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
regulation of homeostatic process GO:0032844 182 0.012
negative regulation of cell development GO:0010721 169 0.012
negative regulation of cell cycle GO:0045786 123 0.012
epithelial cell development GO:0002064 159 0.012
regulation of organ morphogenesis GO:2000027 144 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
Worm
protein modification by small protein conjugation or removal GO:0070647 207 0.012
endocytosis GO:0006897 168 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
neuromuscular process GO:0050905 99 0.012
spermatid differentiation GO:0048515 115 0.012
mapk cascade GO:0000165 281 0.012
respiratory tube development GO:0030323 167 0.012
protein targeting GO:0006605 143 0.012
heterocycle catabolic process GO:0046700 280 0.012
Worm
homeostasis of number of cells GO:0048872 210 0.012
cardiac ventricle development GO:0003231 83 0.012
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.012
regulation of neurotransmitter levels GO:0001505 87 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
establishment of planar polarity GO:0001736 28 0.012
guanosine containing compound metabolic process GO:1901068 144 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
dendrite development GO:0016358 115 0.011
protein processing GO:0016485 163 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
multi multicellular organism process GO:0044706 109 0.011
dna alkylation GO:0006305 43 0.011
cell fate commitment GO:0045165 210 0.011
cell activation involved in immune response GO:0002263 126 0.011
protein ubiquitination GO:0016567 171 0.011
calcium ion dependent exocytosis GO:0017156 35 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
female gamete generation GO:0007292 74 0.011
cerebral cortex cell migration GO:0021795 44 0.011
protein catabolic process GO:0030163 221 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
gtp metabolic process GO:0046039 144 0.011
asymmetric stem cell division GO:0098722 3 0.011
negative regulation of molecular function GO:0044092 258 0.011
lymphocyte differentiation GO:0030098 242 0.011
mrna metabolic process GO:0016071 84 0.011
Worm
tissue homeostasis GO:0001894 115 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
placenta development GO:0001890 140 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
calcium ion transport GO:0006816 159 0.011
positive regulation of kinase activity GO:0033674 155 0.011
mitotic cell cycle GO:0000278 195 0.011
cognition GO:0050890 149 0.011
gonad development GO:0008406 141 0.011
cerebellum development GO:0021549 77 0.011
myelination GO:0042552 74 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
cytokine production GO:0001816 319 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
limb development GO:0060173 166 0.011
establishment of tissue polarity GO:0007164 28 0.011
b cell activation GO:0042113 161 0.011
liver development GO:0001889 66 0.011
protein polymerization GO:0051258 57 0.011
cerebral cortex development GO:0021987 86 0.011
mammary placode formation GO:0060596 4 0.010
microtubule based process GO:0007017 236 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
cation homeostasis GO:0055080 212 0.010
adaptive immune response GO:0002250 155 0.010
regulation of cell adhesion GO:0030155 154 0.010
central nervous system neuron differentiation GO:0021953 162 0.010
microtubule cytoskeleton organization GO:0000226 157 0.010
negative regulation of nervous system development GO:0051961 156 0.010
regulation of metal ion transport GO:0010959 106 0.010
regulation of kinase activity GO:0043549 249 0.010
protein autophosphorylation GO:0046777 61 0.010
chemotaxis GO:0006935 247 0.010
regulation of cell cycle phase transition GO:1901987 77 0.010
positive regulation of creb transcription factor activity GO:0032793 4 0.010
regulation of anatomical structure size GO:0090066 178 0.010
regulation of protein kinase activity GO:0045859 232 0.010
regulation of t cell activation GO:0050863 170 0.010
adult behavior GO:0030534 135 0.010
response to insulin GO:0032868 100 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.010

Smg6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
immune system disease DOID:2914 0 0.022
hematopoietic system disease DOID:74 0 0.016
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015