Mus musculus

0 known processes

Kynu

kynureninase (L-kynurenine hydrolase)

(Aliases: 4432411A05Rik)

Kynu biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune effector process GO:0002252 321 0.174
innate immune response GO:0045087 157 0.172
cytokine production GO:0001816 319 0.154
response to molecule of bacterial origin GO:0002237 143 0.145
reactive nitrogen species metabolic process GO:2001057 0 0.130
regulation of defense response GO:0031347 233 0.125
regulation of cytokine production GO:0001817 266 0.119
reactive oxygen species biosynthetic process GO:1903409 8 0.114
cellular response to lipid GO:0071396 145 0.094
calcitriol biosynthetic process from calciol GO:0036378 3 0.092
regulation of innate immune response GO:0045088 91 0.092
reactive oxygen species metabolic process GO:0072593 84 0.087
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.087
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.082
immune response regulating signaling pathway GO:0002764 125 0.082
oxidation reduction process GO:0055114 342 0.080
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.074
cellular amino acid metabolic process GO:0006520 103 0.072
regulation of reactive oxygen species metabolic process GO:2000377 40 0.070
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.070
cation transport GO:0006812 399 0.069
activation of immune response GO:0002253 138 0.069
response to lipopolysaccharide GO:0032496 128 0.069
cellular response to molecule of bacterial origin GO:0071219 83 0.069
defense response to bacterium GO:0042742 119 0.069
positive regulation of innate immune response GO:0045089 80 0.068
response to organonitrogen compound GO:0010243 246 0.067
cellular ketone metabolic process GO:0042180 84 0.067
myeloid cell differentiation GO:0030099 233 0.067
positive regulation of cytokine production GO:0001819 174 0.065
g protein coupled receptor signaling pathway GO:0007186 243 0.065
regulation of protein localization GO:0032880 231 0.064
amine metabolic process GO:0009308 45 0.062
cellular response to lipopolysaccharide GO:0071222 77 0.061
leukocyte differentiation GO:0002521 342 0.061
cation homeostasis GO:0055080 212 0.060
positive regulation of defense response GO:0031349 124 0.060
membrane organization GO:0061024 245 0.059
positive regulation of secretion GO:0051047 130 0.058
defense response to other organism GO:0098542 197 0.058
lymphocyte proliferation GO:0046651 164 0.057
regulation of secretion GO:0051046 274 0.057
regulation of secretion by cell GO:1903530 249 0.056
fatty acid metabolic process GO:0006631 121 0.055
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.054
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.054
sensory perception GO:0007600 245 0.054
leukocyte activation involved in immune response GO:0002366 126 0.053
glucuronate metabolic process GO:0019585 2 0.053
leukocyte mediated immunity GO:0002443 174 0.052
cellular amine metabolic process GO:0044106 44 0.052
t cell activation GO:0042110 289 0.051
regulation of response to wounding GO:1903034 189 0.051
lipid biosynthetic process GO:0008610 179 0.051
cellular lipid metabolic process GO:0044255 323 0.050
regulation of inflammatory response GO:0050727 147 0.049
negative regulation of immune system process GO:0002683 209 0.048
monocarboxylic acid metabolic process GO:0032787 191 0.048
regulation of leukocyte mediated immunity GO:0002703 104 0.048
immune response activating signal transduction GO:0002757 116 0.047
toxin catabolic process GO:0009407 1 0.046
regulation of establishment of protein localization GO:0070201 181 0.046
cellular alcohol biosynthetic process GO:0044108 3 0.045
cellular response to biotic stimulus GO:0071216 92 0.044
organic hydroxy compound metabolic process GO:1901615 203 0.043
response to organic cyclic compound GO:0014070 198 0.043
regulation of cell activation GO:0050865 289 0.042
positive regulation of immune effector process GO:0002699 107 0.042
mapk cascade GO:0000165 281 0.042
positive regulation of cellular amine metabolic process GO:0033240 5 0.042
regulation of mapk cascade GO:0043408 248 0.041
transmembrane transport GO:0055085 412 0.041
cellular homeostasis GO:0019725 240 0.041
xenobiotic catabolic process GO:0042178 1 0.041
protein secretion GO:0009306 111 0.041
regulation of lymphocyte activation GO:0051249 240 0.041
oxidative demethylation GO:0070989 1 0.040
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
cellular metal ion homeostasis GO:0006875 151 0.040
sequestering of calcium ion GO:0051208 18 0.040
positive regulation of secretion by cell GO:1903532 114 0.039
calcium ion homeostasis GO:0055074 127 0.038
cell activation involved in immune response GO:0002263 126 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.037
naphthalene metabolic process GO:0018931 1 0.037
inflammatory response GO:0006954 244 0.037
maintenance of location GO:0051235 89 0.037
regulation of protein kinase activity GO:0045859 232 0.037
cellular ion homeostasis GO:0006873 165 0.036
response to drug GO:0042493 75 0.036
secondary alcohol metabolic process GO:1902652 3 0.036
sequestering of metal ion GO:0051238 19 0.036
regulation of cellular amine metabolic process GO:0033238 20 0.036
ion transmembrane transport GO:0034220 361 0.035
response to molecule of fungal origin GO:0002238 4 0.035
alcohol metabolic process GO:0006066 116 0.035
regulation of leukocyte proliferation GO:0070663 121 0.035
positive regulation of cell death GO:0010942 224 0.035
metal ion homeostasis GO:0055065 189 0.035
organic cyclic compound catabolic process GO:1901361 295 0.034
regulation of protein transport GO:0051223 163 0.034
cellular alcohol metabolic process GO:0044107 3 0.034
anatomical structure homeostasis GO:0060249 145 0.034
naphthalene containing compound metabolic process GO:0090420 1 0.033
regulation of vesicle mediated transport GO:0060627 139 0.033
aromatic compound catabolic process GO:0019439 286 0.033
leukocyte mediated cytotoxicity GO:0001909 62 0.033
uronic acid metabolic process GO:0006063 2 0.033
nucleotide metabolic process GO:0009117 332 0.033
macromolecule catabolic process GO:0009057 281 0.032
vitamin d3 metabolic process GO:0070640 3 0.032
nitrogen compound transport GO:0071705 271 0.032
cellular chemical homeostasis GO:0055082 215 0.031
protein maturation GO:0051604 176 0.031
detection of fungus GO:0016046 2 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
cellular response to organonitrogen compound GO:0071417 145 0.030
positive regulation of protein modification process GO:0031401 299 0.030
regulation of blood pressure GO:0008217 93 0.030
regulation of system process GO:0044057 200 0.029
regulation of cell migration GO:0030334 219 0.029
organonitrogen compound catabolic process GO:1901565 264 0.029
positive regulation of protein transport GO:0051222 93 0.028
regulation of membrane potential GO:0042391 192 0.027
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.027
regulation of lymphocyte proliferation GO:0050670 117 0.027
anion transport GO:0006820 177 0.027
positive regulation of lymphocyte activation GO:0051251 140 0.027
t cell differentiation GO:0030217 174 0.027
multicellular organismal homeostasis GO:0048871 164 0.026
organonitrogen compound biosynthetic process GO:1901566 192 0.026
positive regulation of transferase activity GO:0051347 167 0.026
regulation of ion transport GO:0043269 215 0.026
regulation of cell motility GO:2000145 236 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
negative regulation of intracellular signal transduction GO:1902532 167 0.025
regulation of cellular component biogenesis GO:0044087 181 0.025
negative regulation of defense response GO:0031348 77 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
hematopoietic progenitor cell differentiation GO:0002244 143 0.025
myeloid leukocyte activation GO:0002274 83 0.025
heterocycle catabolic process GO:0046700 280 0.025
cellular response to peptidoglycan GO:0071224 4 0.025
ribonucleoside metabolic process GO:0009119 245 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.024
leukocyte proliferation GO:0070661 172 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
positive regulation of cell activation GO:0050867 158 0.024
detection of yeast GO:0001879 2 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
apoptotic signaling pathway GO:0097190 306 0.024
cell killing GO:0001906 67 0.024
regulation of cytokine secretion GO:0050707 61 0.024
regulation of hormone levels GO:0010817 211 0.024
cation transmembrane transport GO:0098655 266 0.024
glycoprotein biosynthetic process GO:0009101 89 0.024
cellular calcium ion homeostasis GO:0006874 119 0.023
cell adhesion GO:0007155 329 0.023
carbohydrate metabolic process GO:0005975 230 0.023
regulation of protein secretion GO:0050708 82 0.023
purine containing compound metabolic process GO:0072521 311 0.023
small molecule biosynthetic process GO:0044283 132 0.023
dna metabolic process GO:0006259 303 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
protein catabolic process GO:0030163 221 0.023
regulation of kinase activity GO:0043549 249 0.023
blood vessel morphogenesis GO:0048514 285 0.023
transmission of nerve impulse GO:0019226 76 0.023
action potential GO:0001508 78 0.023
peptidyl amino acid modification GO:0018193 336 0.023
positive regulation of kinase activity GO:0033674 155 0.022
regulation of interferon gamma production GO:0032649 57 0.022
response to acid chemical GO:0001101 111 0.022
cytokine metabolic process GO:0042107 71 0.022
defense response to gram positive bacterium GO:0050830 50 0.022
sulfur compound metabolic process GO:0006790 100 0.022
divalent metal ion transport GO:0070838 172 0.022
regulation of lymphocyte mediated immunity GO:0002706 84 0.022
production of molecular mediator of immune response GO:0002440 103 0.022
interferon beta biosynthetic process GO:0045350 4 0.021
cofactor metabolic process GO:0051186 80 0.021
ras protein signal transduction GO:0007265 77 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
ossification GO:0001503 216 0.021
regulation of ion homeostasis GO:2000021 64 0.021
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.021
medium chain fatty acid metabolic process GO:0051791 1 0.021
endocytosis GO:0006897 168 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.021
regulation of leukocyte differentiation GO:1902105 159 0.021
multicellular organismal signaling GO:0035637 91 0.021
tissue homeostasis GO:0001894 115 0.021
extracellular matrix organization GO:0030198 147 0.020
regulation of cell killing GO:0031341 40 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
positive regulation of cell killing GO:0031343 33 0.020
wnt signaling pathway GO:0016055 188 0.020
positive regulation of cytokine biosynthetic process GO:0042108 40 0.020
lymphocyte mediated immunity GO:0002449 139 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
cytoplasmic transport GO:0016482 234 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
positive regulation of interferon alpha production GO:0032727 4 0.020
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.020
cytokine secretion GO:0050663 72 0.020
eosinophil activation involved in immune response GO:0002278 1 0.020
microglial cell activation GO:0001774 3 0.020
erk1 and erk2 cascade GO:0070371 77 0.020
alpha beta t cell activation GO:0046631 91 0.020
protein processing GO:0016485 163 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
divalent inorganic cation transport GO:0072511 178 0.019
nucleoside metabolic process GO:0009116 246 0.019
response to extracellular stimulus GO:0009991 127 0.019
negative regulation of immune effector process GO:0002698 55 0.019
microglial cell activation involved in immune response GO:0002282 1 0.019
fat soluble vitamin biosynthetic process GO:0042362 4 0.019
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
pattern recognition receptor signaling pathway GO:0002221 47 0.019
fat cell differentiation GO:0045444 160 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
adaptive immune response GO:0002250 155 0.019
intestinal epithelial structure maintenance GO:0060729 4 0.019
unsaturated fatty acid metabolic process GO:0033559 31 0.019
modification by symbiont of host morphology or physiology GO:0044003 4 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
lymphocyte differentiation GO:0030098 242 0.018
regulation of natural killer cell mediated immunity GO:0002715 19 0.018
muscle tissue development GO:0060537 308 0.018
chemotaxis GO:0006935 247 0.018
regulation of transferase activity GO:0051338 263 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
glycoprotein metabolic process GO:0009100 116 0.018
regulation of organelle organization GO:0033043 289 0.018
positive regulation of leukocyte proliferation GO:0070665 73 0.018
natural killer cell mediated immunity GO:0002228 29 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
regulation of t cell activation GO:0050863 170 0.018
positive regulation of interferon gamma production GO:0032729 39 0.018
nucleoside catabolic process GO:0009164 206 0.018
icosanoid metabolic process GO:0006690 33 0.018
nucleotide catabolic process GO:0009166 217 0.018
single organism cell adhesion GO:0098602 156 0.018
regulation of interleukin 8 production GO:0032677 3 0.018
cell type specific apoptotic process GO:0097285 268 0.017
positive regulation of leukocyte mediated immunity GO:0002705 70 0.017
regulation of interferon beta biosynthetic process GO:0045357 4 0.017
cellular response to acid chemical GO:0071229 68 0.017
carboxylic acid transport GO:0046942 100 0.017
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
amino acid transport GO:0006865 61 0.017
defense response to gram negative bacterium GO:0050829 28 0.017
blood circulation GO:0008015 195 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
regulation of body fluid levels GO:0050878 162 0.017
exocytosis GO:0006887 121 0.017
regulation of homeostatic process GO:0032844 182 0.017
steroid metabolic process GO:0008202 119 0.017
positive regulation of interleukin 18 production GO:0032741 2 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
response to steroid hormone GO:0048545 56 0.017
digestive tract development GO:0048565 190 0.017
transepithelial chloride transport GO:0030321 4 0.017
kidney development GO:0001822 213 0.017
antibacterial peptide biosynthetic process GO:0002780 2 0.017
interleukin 18 production GO:0032621 4 0.017
helper t cell chemotaxis GO:0035704 1 0.017
b cell activation GO:0042113 161 0.017
interleukin 8 production GO:0032637 4 0.017
negative regulation of homeostatic process GO:0032845 71 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.017
inter male aggressive behavior GO:0002121 3 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
b cell proliferation GO:0042100 53 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
regulation of immunological synapse formation GO:2000520 2 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
forebrain development GO:0030900 302 0.016
calcium ion transport GO:0006816 159 0.016
carboxylic acid biosynthetic process GO:0046394 86 0.016
angiogenesis GO:0001525 201 0.016
homeostasis of number of cells GO:0048872 210 0.016
regulation of proteolysis GO:0030162 164 0.016
secondary metabolite catabolic process GO:0090487 1 0.016
humoral immune response GO:0006959 57 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
glial cell differentiation GO:0010001 131 0.016
monocyte extravasation GO:0035696 2 0.016
rho protein signal transduction GO:0007266 32 0.016
t cell proliferation GO:0042098 120 0.016
regulation of endocytosis GO:0030100 69 0.016
endomembrane system organization GO:0010256 147 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
purine containing compound catabolic process GO:0072523 213 0.016
response to growth factor GO:0070848 198 0.016
positive regulation of nervous system development GO:0051962 221 0.016
regulation of cellular response to stress GO:0080135 159 0.016
cytokine biosynthetic process GO:0042089 68 0.016
protein ubiquitination GO:0016567 171 0.016
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.016
synaptic transmission GO:0007268 329 0.015
glucose homeostasis GO:0042593 128 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
regulation of cell cycle GO:0051726 281 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
organic acid transport GO:0015849 101 0.015
natural killer cell mediated cytotoxicity GO:0042267 29 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
antigen receptor mediated signaling pathway GO:0050851 64 0.015
organic hydroxy compound transport GO:0015850 93 0.015
antigen processing and presentation GO:0019882 47 0.015
negative regulation of molecular function GO:0044092 258 0.015
regulation of neuron differentiation GO:0045664 281 0.015
positive regulation of cell migration GO:0030335 109 0.015
leukocyte migration GO:0050900 124 0.015
negative regulation of cell activation GO:0050866 111 0.015
hormone secretion GO:0046879 128 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
interferon gamma production GO:0032609 67 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
organic anion transport GO:0015711 137 0.015
regulation of interleukin 18 production GO:0032661 3 0.015
activation of innate immune response GO:0002218 56 0.015
response to host GO:0075136 3 0.015
innate immune response activating signal transduction GO:0002758 50 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
regulation of systemic arterial blood pressure GO:0003073 61 0.014
positive regulation of interleukin 8 production GO:0032757 2 0.014
organic acid biosynthetic process GO:0016053 86 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.014
multi multicellular organism process GO:0044706 109 0.014
hormone metabolic process GO:0042445 86 0.014
cofactor transport GO:0051181 4 0.014
developmental maturation GO:0021700 193 0.014
glycerolipid metabolic process GO:0046486 122 0.014
cellular protein catabolic process GO:0044257 155 0.014
carbohydrate homeostasis GO:0033500 128 0.014
organelle localization GO:0051640 179 0.014
plasma membrane organization GO:0007009 90 0.014
actin cytoskeleton organization GO:0030036 220 0.014
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
response to nutrient levels GO:0031667 109 0.014
spermatogenesis GO:0007283 284 0.014
germ cell development GO:0007281 185 0.014
activation of mapk activity GO:0000187 59 0.014
purine nucleotide metabolic process GO:0006163 302 0.014
lipid transport GO:0006869 98 0.014
regulation of intracellular transport GO:0032386 159 0.014
regulation of cell projection organization GO:0031344 206 0.014
response to peptide GO:1901652 136 0.014
regulation of cytokine biosynthetic process GO:0042035 59 0.014
regulation of cell cycle process GO:0010564 160 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
regulation of hormone secretion GO:0046883 88 0.014
muscle cell differentiation GO:0042692 261 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
renal system development GO:0072001 225 0.014
skeletal system morphogenesis GO:0048705 203 0.014
b cell activation involved in immune response GO:0002312 50 0.014
respiratory system development GO:0060541 190 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
peptide transport GO:0015833 133 0.014
amino acid transmembrane transport GO:0003333 37 0.014
cell chemotaxis GO:0060326 81 0.014
regulation of t cell costimulation GO:2000523 2 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
nitric oxide metabolic process GO:0046209 25 0.014
regulation of anatomical structure size GO:0090066 178 0.013
cellular response to oxidative stress GO:0034599 76 0.013
leukocyte degranulation GO:0043299 27 0.013
male gamete generation GO:0048232 285 0.013
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.013
regulation of interleukin 6 production GO:0032675 55 0.013
interleukin 6 production GO:0032635 58 0.013
organic hydroxy compound biosynthetic process GO:1901617 77 0.013
regulation of eosinophil degranulation GO:0043309 1 0.013
cellular response to molecule of fungal origin GO:0071226 2 0.013
alcohol biosynthetic process GO:0046165 43 0.013
leukocyte chemotaxis GO:0030595 69 0.013
terpenoid metabolic process GO:0006721 25 0.013
cellular amide metabolic process GO:0043603 58 0.013
regulation of t cell proliferation GO:0042129 92 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
positive regulation of protein secretion GO:0050714 52 0.013
cytosolic calcium ion homeostasis GO:0051480 70 0.013
regulation of b cell activation GO:0050864 81 0.013
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
regulation of chemokine production GO:0032642 30 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
regulation of erk1 and erk2 cascade GO:0070372 71 0.013
skeletal system development GO:0001501 356 0.013
progesterone metabolic process GO:0042448 4 0.013
protein localization to organelle GO:0033365 185 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
regulation of tube size GO:0035150 57 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
antimicrobial peptide production GO:0002775 2 0.013
lipid localization GO:0010876 126 0.013
cellular response to external stimulus GO:0071496 88 0.013
organelle assembly GO:0070925 177 0.013
negative regulation of leukocyte mediated immunity GO:0002704 29 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
regulation of hydrolase activity GO:0051336 246 0.012
positive regulation of t cell costimulation GO:2000525 2 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
circulatory system process GO:0003013 197 0.012
positive regulation of cytokine secretion GO:0050715 41 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.012
regulation of cell adhesion GO:0030155 154 0.012
negative regulation of protein modification process GO:0031400 163 0.012
pallium development GO:0021543 120 0.012
eosinophil activation GO:0043307 1 0.012
response to testosterone GO:0033574 3 0.012
cellular protein complex assembly GO:0043623 116 0.012
regulation of protein maturation GO:1903317 96 0.012
positive regulation of cell motility GO:2000147 116 0.012
nitric oxide biosynthetic process GO:0006809 25 0.012
sulfur compound biosynthetic process GO:0044272 37 0.012
cell substrate adhesion GO:0031589 130 0.012
cell growth GO:0016049 130 0.012
vitamin d biosynthetic process GO:0042368 3 0.012
tissue remodeling GO:0048771 102 0.012
monocarboxylic acid biosynthetic process GO:0072330 61 0.012
ear development GO:0043583 200 0.012
carbohydrate transport GO:0008643 62 0.012
detection of stimulus GO:0051606 84 0.012
regulation of protein complex assembly GO:0043254 83 0.012
response to inorganic substance GO:0010035 96 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
response to peptide hormone GO:0043434 127 0.012
digestive system development GO:0055123 200 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
positive regulation of tumor necrosis factor production GO:0032760 30 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.012
drug catabolic process GO:0042737 2 0.012
compound eye development GO:0048749 1 0.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.012
tumor necrosis factor production GO:0032640 50 0.012
fatty acid derivative metabolic process GO:1901568 33 0.012
cellular response to cadmium ion GO:0071276 3 0.012
positive regulation of map kinase activity GO:0043406 84 0.012
drug metabolic process GO:0017144 4 0.012
anion transmembrane transport GO:0098656 71 0.012
response to oxidative stress GO:0006979 123 0.012
regulation of muscle system process GO:0090257 80 0.012
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.012
epithelial cell proliferation GO:0050673 174 0.012
monosaccharide metabolic process GO:0005996 106 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.011

Kynu disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.035
disease of anatomical entity DOID:7 0 0.035
disease of metabolism DOID:0014667 0 0.030
musculoskeletal system disease DOID:17 0 0.026
nervous system disease DOID:863 0 0.026
hematopoietic system disease DOID:74 0 0.026
connective tissue disease DOID:65 0 0.024
hemolytic anemia DOID:583 0 0.018
hemolytic uremic syndrome DOID:12554 0 0.018
normocytic anemia DOID:720 0 0.018
anemia DOID:2355 0 0.018
sensory system disease DOID:0050155 0 0.018
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.012
bone disease DOID:0080001 0 0.012