Mus musculus

208 known processes

Mkks

McKusick-Kaufman syndrome protein

(Aliases: 1300013E18Rik,AI463362,MGC143766,AI957237,Bbs6)

Mkks biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cilium assembly GO:1902017 7 0.172
multicellular organismal homeostasis GO:0048871 164 0.067
retina homeostasis GO:0001895 23 0.055
cellular response to leptin stimulus GO:0044320 6 0.050
anatomical structure homeostasis GO:0060249 145 0.050
oxidation reduction process GO:0055114 342 0.049
cellular component assembly involved in morphogenesis GO:0010927 139 0.048
adult behavior GO:0030534 135 0.047
microtubule based process GO:0007017 236 0.046
dna metabolic process GO:0006259 303 0.045
establishment of melanosome localization GO:0032401 11 0.044
Zebrafish
sensory perception GO:0007600 245 0.041
cellular amino acid metabolic process GO:0006520 103 0.040
cilium assembly GO:0042384 81 0.040
cellular lipid metabolic process GO:0044255 323 0.038
spermatid differentiation GO:0048515 115 0.037
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
intraciliary retrograde transport GO:0035721 3 0.036
cellular amine metabolic process GO:0044106 44 0.034
amine metabolic process GO:0009308 45 0.034
nonmotile primary cilium assembly GO:0035058 8 0.033
regulation of organelle organization GO:0033043 289 0.033
microtubule cytoskeleton organization GO:0000226 157 0.033
cerebral cortex development GO:0021987 86 0.033
pigment granule localization GO:0051875 13 0.033
Zebrafish
regulation of cellular ketone metabolic process GO:0010565 66 0.032
multicellular organism growth GO:0035264 161 0.031
organelle localization GO:0051640 179 0.031
Zebrafish
melanosome transport GO:0032402 11 0.029
Zebrafish
regulation of cell cycle GO:0051726 281 0.028
pallium development GO:0021543 120 0.027
cell type specific apoptotic process GO:0097285 268 0.027
forebrain development GO:0030900 302 0.027
organelle assembly GO:0070925 177 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
mitotic cell cycle GO:0000278 195 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
cilium morphogenesis GO:0060271 102 0.026
spermatogenesis GO:0007283 284 0.025
positive regulation of growth GO:0045927 104 0.025
germ cell development GO:0007281 185 0.024
cellular ketone metabolic process GO:0042180 84 0.024
lipid biosynthetic process GO:0008610 179 0.024
sensory organ morphogenesis GO:0090596 242 0.023
regulation of cilium movement GO:0003352 6 0.023
tube closure GO:0060606 91 0.023
cellular homeostasis GO:0019725 240 0.023
cilium dependent cell motility GO:0060285 6 0.023
negative regulation of molecular function GO:0044092 258 0.022
regulation of lipid metabolic process GO:0019216 118 0.022
regulation of cilium movement involved in cell motility GO:0060295 5 0.022
regulation of hormone levels GO:0010817 211 0.022
tissue homeostasis GO:0001894 115 0.021
protein localization to organelle GO:0033365 185 0.021
blood circulation GO:0008015 195 0.021
vesicle localization GO:0051648 86 0.021
Zebrafish
regulation of cellular amine metabolic process GO:0033238 20 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
dendrite development GO:0016358 115 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
fat cell differentiation GO:0045444 160 0.020
positive regulation of organelle organization GO:0010638 128 0.020
developmental pigmentation GO:0048066 40 0.020
transmembrane transport GO:0055085 412 0.020
hormone metabolic process GO:0042445 86 0.019
regulation of cell cycle process GO:0010564 160 0.019
axis elongation involved in somitogenesis GO:0090245 4 0.019
mitochondrion organization GO:0007005 134 0.019
striatum development GO:0021756 14 0.019
telencephalon development GO:0021537 186 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
cellular chemical homeostasis GO:0055082 215 0.018
striated muscle tissue development GO:0014706 293 0.018
response to extracellular stimulus GO:0009991 127 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
heterocycle catabolic process GO:0046700 280 0.018
muscle tissue development GO:0060537 308 0.017
skeletal system development GO:0001501 356 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
male gamete generation GO:0048232 285 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.017
leukocyte differentiation GO:0002521 342 0.017
peptidyl amino acid modification GO:0018193 336 0.016
regulation of cilium beat frequency involved in ciliary motility GO:0060296 5 0.016
embryonic epithelial tube formation GO:0001838 130 0.016
microtubule anchoring at microtubule organizing center GO:0072393 5 0.016
innate immune response GO:0045087 157 0.016
regulation of neuron differentiation GO:0045664 281 0.016
nitrogen compound transport GO:0071705 271 0.016
sensory perception of smell GO:0007608 26 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
microtubule organizing center organization GO:0031023 28 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
response to nutrient levels GO:0031667 109 0.016
muscle cell differentiation GO:0042692 261 0.016
limbic system development GO:0021761 72 0.015
establishment of vesicle localization GO:0051650 81 0.015
Zebrafish
negative regulation of blood pressure GO:0045776 22 0.015
response to organonitrogen compound GO:0010243 246 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
Zebrafish
neural tube development GO:0021915 160 0.015
response to organic cyclic compound GO:0014070 198 0.015
circulatory system process GO:0003013 197 0.015
regulation of cell activation GO:0050865 289 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
dephosphorylation GO:0016311 129 0.015
neural tube closure GO:0001843 90 0.015
muscle contraction GO:0006936 101 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
cation homeostasis GO:0055080 212 0.015
melanosome localization GO:0032400 12 0.015
Zebrafish
nucleotide metabolic process GO:0009117 332 0.015
aromatic compound catabolic process GO:0019439 286 0.015
mitotic cell cycle process GO:1903047 159 0.014
purine containing compound metabolic process GO:0072521 311 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
ventricular system development GO:0021591 27 0.014
cytokine mediated signaling pathway GO:0019221 115 0.014
spermatid development GO:0007286 108 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
coenzyme metabolic process GO:0006732 52 0.014
digestive system development GO:0055123 200 0.014
Zebrafish
mitotic cytokinesis GO:0000281 4 0.014
regulation of mapk cascade GO:0043408 248 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
cilium movement involved in cell motility GO:0060294 5 0.014
intracellular protein transport GO:0006886 204 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
neural precursor cell proliferation GO:0061351 121 0.014
immune effector process GO:0002252 321 0.014
negative regulation of systemic arterial blood pressure GO:0003085 15 0.014
cellular protein complex assembly GO:0043623 116 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
primary neural tube formation GO:0014020 95 0.013
positive regulation of protein modification process GO:0031401 299 0.013
mapk cascade GO:0000165 281 0.013
urogenital system development GO:0001655 261 0.013
pigment granule transport GO:0051904 12 0.013
Zebrafish
heart morphogenesis GO:0003007 178 0.013
Zebrafish
response to radiation GO:0009314 165 0.013
apoptotic signaling pathway GO:0097190 306 0.013
centrosome organization GO:0051297 26 0.013
regulation of homeostatic process GO:0032844 182 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
gland development GO:0048732 330 0.013
macromolecule catabolic process GO:0009057 281 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
synaptic transmission GO:0007268 329 0.013
photoreceptor cell differentiation GO:0046530 52 0.013
cellular ion homeostasis GO:0006873 165 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
regulation of cell division GO:0051302 76 0.013
locomotory behavior GO:0007626 195 0.013
defense response to other organism GO:0098542 197 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
regulation of ion transport GO:0043269 215 0.012
negative regulation of protein modification process GO:0031400 163 0.012
regulation of cellular response to stress GO:0080135 159 0.012
epithelial cell development GO:0002064 159 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
regulation of cell motility GO:2000145 236 0.012
nucleoside metabolic process GO:0009116 246 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
kidney development GO:0001822 213 0.012
epithelial tube formation GO:0072175 130 0.012
negative regulation of immune system process GO:0002683 209 0.012
protein localization to nucleus GO:0034504 121 0.012
metal ion homeostasis GO:0055065 189 0.012
pigmentation GO:0043473 71 0.012
Zebrafish
regulation of systemic arterial blood pressure GO:0003073 61 0.012
macromolecule methylation GO:0043414 120 0.012
regulation of protein kinase activity GO:0045859 232 0.011
regulation of membrane potential GO:0042391 192 0.011
photoreceptor cell morphogenesis GO:0008594 3 0.011
respiratory system development GO:0060541 190 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
ras protein signal transduction GO:0007265 77 0.011
neuron apoptotic process GO:0051402 142 0.011
photoreceptor cell development GO:0042461 40 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
digestive tract development GO:0048565 190 0.011
Zebrafish
regulation of cell projection organization GO:0031344 206 0.011
maintenance of location GO:0051235 89 0.011
eye pigmentation GO:0048069 3 0.011
fertilization GO:0009566 127 0.011
cation transmembrane transport GO:0098655 266 0.011
divalent inorganic cation transport GO:0072511 178 0.011
cytoplasmic transport GO:0016482 234 0.011
rho protein signal transduction GO:0007266 32 0.011
somitogenesis GO:0001756 69 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
cation transport GO:0006812 399 0.011
methylation GO:0032259 134 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
protein maturation GO:0051604 176 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
regulation of protein localization GO:0032880 231 0.011
generation of precursor metabolites and energy GO:0006091 103 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
sequestering of metal ion GO:0051238 19 0.011
adult locomotory behavior GO:0008344 91 0.011
regulation of secretion GO:0051046 274 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
inflammatory response GO:0006954 244 0.010
regulation of response to food GO:0032095 10 0.010
positive regulation of nervous system development GO:0051962 221 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
chromatin organization GO:0006325 206 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
carbohydrate metabolic process GO:0005975 230 0.010
ear development GO:0043583 200 0.010
Zebrafish
hippocampus development GO:0021766 52 0.010
regulation of cilium dependent cell motility GO:1902019 5 0.010
cellular macromolecule catabolic process GO:0044265 206 0.010
divalent metal ion transport GO:0070838 172 0.010
purine ribonucleotide metabolic process GO:0009150 290 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010

Mkks disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
sensory system disease DOID:0050155 0 0.015
immune system disease DOID:2914 0 0.014
central nervous system disease DOID:331 0 0.011