Mus musculus

97 known processes

Icmt

isoprenylcysteine carboxyl methyltransferase

(Aliases: Gm13095,MGC118506,1700008E11Rik,HSTE14,OTTMUSG00000010406,C80758,STE14,PPMT,pcCMT)

Icmt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular mrna localization GO:0008298 4 0.114
oocyte axis specification GO:0007309 2 0.079
protein modification by small protein conjugation GO:0032446 187 0.076
ubiquitin dependent protein catabolic process GO:0006511 129 0.075
pole plasm assembly GO:0007315 2 0.067
nucleoside phosphate catabolic process GO:1901292 222 0.066
oocyte construction GO:0007308 2 0.064
negative regulation of protein metabolic process GO:0051248 282 0.061
positive regulation of protein modification process GO:0031401 299 0.058
protein catabolic process GO:0030163 221 0.058
protein localization to organelle GO:0033365 185 0.058
modification dependent protein catabolic process GO:0019941 133 0.057
negative regulation of molecular function GO:0044092 258 0.056
response to light stimulus GO:0009416 135 0.055
purine nucleotide metabolic process GO:0006163 302 0.054
modification dependent macromolecule catabolic process GO:0043632 133 0.052
regulation of transferase activity GO:0051338 263 0.046
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.045
cellular protein catabolic process GO:0044257 155 0.043
male gamete generation GO:0048232 285 0.043
membrane organization GO:0061024 245 0.041
protein localization to nucleus GO:0034504 121 0.040
negative regulation of cell development GO:0010721 169 0.036
macromolecule catabolic process GO:0009057 281 0.035
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.035
apoptotic signaling pathway GO:0097190 306 0.035
multi multicellular organism process GO:0044706 109 0.035
maternal determination of anterior posterior axis embryo GO:0008358 2 0.034
negative regulation of cellular protein metabolic process GO:0032269 247 0.034
response to radiation GO:0009314 165 0.033
spermatogenesis GO:0007283 284 0.033
dna metabolic process GO:0006259 303 0.032
learning or memory GO:0007611 148 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.032
cytoplasmic transport GO:0016482 234 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.031
locomotory behavior GO:0007626 195 0.031
transmembrane transport GO:0055085 412 0.031
regulation of neuron differentiation GO:0045664 281 0.031
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.030
aromatic compound catabolic process GO:0019439 286 0.030
regulation of kinase activity GO:0043549 249 0.030
adult behavior GO:0030534 135 0.030
purine containing compound metabolic process GO:0072521 311 0.029
inorganic cation transmembrane transport GO:0098662 207 0.029
ribose phosphate metabolic process GO:0019693 291 0.028
oocyte anterior posterior axis specification GO:0007314 2 0.028
circadian rhythm GO:0007623 114 0.028
protein maturation GO:0051604 176 0.028
response to growth factor GO:0070848 198 0.027
peptidyl amino acid modification GO:0018193 336 0.027
cellular macromolecule catabolic process GO:0044265 206 0.027
glycosyl compound catabolic process GO:1901658 206 0.026
lipid transport GO:0006869 98 0.026
regulation of wnt signaling pathway GO:0030111 123 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
regulation of cell cycle GO:0051726 281 0.026
regulation of vesicle mediated transport GO:0060627 139 0.026
regulation of protein kinase activity GO:0045859 232 0.026
microtubule based process GO:0007017 236 0.025
protein ubiquitination GO:0016567 171 0.025
cellular ketone metabolic process GO:0042180 84 0.025
hematopoietic progenitor cell differentiation GO:0002244 143 0.025
cation transmembrane transport GO:0098655 266 0.024
protein localization to membrane GO:0072657 108 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
cellular amine metabolic process GO:0044106 44 0.024
protein targeting GO:0006605 143 0.024
lateral inhibition GO:0046331 1 0.024
tube formation GO:0035148 140 0.024
multicellular organism growth GO:0035264 161 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
neural tube formation GO:0001841 108 0.024
b cell activation GO:0042113 161 0.023
regulation of body fluid levels GO:0050878 162 0.023
regulation of secretion GO:0051046 274 0.023
wound healing GO:0042060 157 0.023
protein localization to endosome GO:0036010 2 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
spermatid development GO:0007286 108 0.023
nitrogen compound transport GO:0071705 271 0.023
regulation of response to wounding GO:1903034 189 0.022
intrinsic apoptotic signaling pathway GO:0097193 132 0.022
digestive tract development GO:0048565 190 0.022
nucleoside catabolic process GO:0009164 206 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
rhythmic process GO:0048511 174 0.022
carbohydrate metabolic process GO:0005975 230 0.022
nucleotide catabolic process GO:0009166 217 0.022
neural precursor cell proliferation GO:0061351 121 0.021
compound eye development GO:0048749 1 0.021
cellular amino acid metabolic process GO:0006520 103 0.021
cation transport GO:0006812 399 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.020
response to organonitrogen compound GO:0010243 246 0.020
lipid localization GO:0010876 126 0.020
protein processing GO:0016485 163 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
nuclear transport GO:0051169 139 0.020
mitotic cell cycle GO:0000278 195 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.019
germ cell development GO:0007281 185 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
proteasomal protein catabolic process GO:0010498 98 0.019
synaptic transmission GO:0007268 329 0.019
intracellular protein transport GO:0006886 204 0.019
positive regulation of gene silencing by mirna GO:2000637 1 0.019
organophosphate catabolic process GO:0046434 232 0.019
regulation of proteolysis GO:0030162 164 0.019
memory GO:0007613 58 0.019
rna localization GO:0006403 23 0.018
stem cell differentiation GO:0048863 268 0.018
endocytosis GO:0006897 168 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
lymphocyte mediated immunity GO:0002449 139 0.018
ion transmembrane transport GO:0034220 361 0.018
nucleotide metabolic process GO:0009117 332 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
regulation of cellular amino acid metabolic process GO:0006521 5 0.018
maintenance of location GO:0051235 89 0.018
carbon catabolite activation of transcription GO:0045991 4 0.017
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.017
establishment or maintenance of cell polarity GO:0007163 86 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
meiosis i GO:0007127 60 0.017
cellular lipid metabolic process GO:0044255 323 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
negative regulation of neuron differentiation GO:0045665 101 0.017
immunoglobulin production GO:0002377 73 0.017
negative regulation of proteolysis GO:0045861 74 0.017
exocytosis GO:0006887 121 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.017
digestive tract morphogenesis GO:0048546 147 0.016
mitotic cell cycle process GO:1903047 159 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.016
mesodermal cell migration GO:0008078 4 0.016
skeletal system development GO:0001501 356 0.016
sensory perception GO:0007600 245 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
digestive system development GO:0055123 200 0.016
ras protein signal transduction GO:0007265 77 0.016
heterocycle catabolic process GO:0046700 280 0.016
fat cell differentiation GO:0045444 160 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
multi organism behavior GO:0051705 62 0.015
regulation of hormone levels GO:0010817 211 0.015
sodium ion transmembrane transport GO:0035725 49 0.015
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
protein localization to plasma membrane GO:0072659 57 0.015
regulation of cell growth GO:0001558 91 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
positive regulation of cell projection organization GO:0031346 95 0.015
negative regulation of nervous system development GO:0051961 156 0.015
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.014
gastrulation GO:0007369 116 0.014
anion transport GO:0006820 177 0.014
regulation of cellular ketone metabolic process GO:0010565 66 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
regulation of protein maturation GO:1903317 96 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
lung morphogenesis GO:0060425 50 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
developmental maturation GO:0021700 193 0.014
cellular response to oxidative stress GO:0034599 76 0.014
leukocyte mediated immunity GO:0002443 174 0.014
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
organic anion transport GO:0015711 137 0.014
negative regulation of protein modification process GO:0031400 163 0.014
male meiosis GO:0007140 37 0.014
coagulation GO:0050817 78 0.014
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.014
nucleocytoplasmic transport GO:0006913 139 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
amino sugar catabolic process GO:0046348 1 0.013
cellular response to cadmium ion GO:0071276 3 0.013
oocyte development GO:0048599 33 0.013
regulation of protein ubiquitination GO:0031396 52 0.013
vesicle organization GO:0016050 60 0.013
neuron death GO:0070997 154 0.013
positive regulation of growth GO:0045927 104 0.013
neuron neuron synaptic transmission GO:0007270 69 0.013
cellularization GO:0007349 1 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
regulation of cellular response to growth factor stimulus GO:0090287 82 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
divalent inorganic cation transport GO:0072511 178 0.013
glucose metabolic process GO:0006006 92 0.013
negative regulation of protein maturation GO:1903318 79 0.013
urogenital system development GO:0001655 261 0.013
negative regulation of protein processing GO:0010955 79 0.013
regulation of cytokine production GO:0001817 266 0.013
response to peptide GO:1901652 136 0.012
cellular response to lipid GO:0071396 145 0.012
amine metabolic process GO:0009308 45 0.012
oogenesis GO:0048477 56 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
cell adhesion GO:0007155 329 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
negative regulation of wnt signaling pathway GO:0030178 73 0.012
chromatin modification GO:0016568 187 0.012
cell growth GO:0016049 130 0.012
regulation of protein processing GO:0070613 96 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
establishment of protein localization to membrane GO:0090150 54 0.012
regulation of cysteine type endopeptidase activity GO:2000116 65 0.012
positive regulation of proteolysis GO:0045862 85 0.012
cell type specific apoptotic process GO:0097285 268 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
cognition GO:0050890 149 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.012
response to insulin GO:0032868 100 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
regulation of cell activation GO:0050865 289 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
rap protein signal transduction GO:0032486 3 0.012
regulation of cellular protein catabolic process GO:1903362 61 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
positive regulation of transferase activity GO:0051347 167 0.011
positive regulation of map kinase activity GO:0043406 84 0.011
negative regulation of kinase activity GO:0033673 81 0.011
regulation of jnk cascade GO:0046328 62 0.011
regulation of circadian sleep wake cycle GO:0042749 3 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
anion transmembrane transport GO:0098656 71 0.011
regulation of protein tyrosine kinase activity GO:0061097 17 0.011
regulation of neuron projection development GO:0010975 169 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.011
organelle localization GO:0051640 179 0.011
regulation of cellular amine metabolic process GO:0033238 20 0.011
snrna processing GO:0016180 1 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
response to uv GO:0009411 44 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
neurotransmitter transport GO:0006836 76 0.011
translation GO:0006412 93 0.011
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
mrna processing GO:0006397 63 0.011
epidermis development GO:0008544 187 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
leukocyte differentiation GO:0002521 342 0.011
endomembrane system organization GO:0010256 147 0.011
nuclear import GO:0051170 95 0.011
regulation of adaptive immune response GO:0002819 90 0.011
determination of left right symmetry GO:0007368 80 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
sodium ion transport GO:0006814 73 0.011
blood vessel morphogenesis GO:0048514 285 0.011
brain morphogenesis GO:0048854 32 0.011
gland development GO:0048732 330 0.011
detection of stimulus GO:0051606 84 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of cell motility GO:2000145 236 0.010
stem cell proliferation GO:0072089 117 0.010
glycerophospholipid metabolic process GO:0006650 71 0.010
regulation of lymphocyte proliferation GO:0050670 117 0.010
adult locomotory behavior GO:0008344 91 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010
homeostasis of number of cells GO:0048872 210 0.010
small gtpase mediated signal transduction GO:0007264 97 0.010
cell junction assembly GO:0034329 52 0.010
purine nucleoside metabolic process GO:0042278 241 0.010
rab protein signal transduction GO:0032482 1 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.010
regulation of protein localization GO:0032880 231 0.010
respiratory tube development GO:0030323 167 0.010
nucleoside metabolic process GO:0009116 246 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.010
tissue homeostasis GO:0001894 115 0.010
monocarboxylic acid transport GO:0015718 44 0.010
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.010
positive regulation of nucleotide catabolic process GO:0030813 88 0.010
regulation of hematopoietic stem cell differentiation GO:1902036 1 0.010
positive regulation of kinase activity GO:0033674 155 0.010
covalent chromatin modification GO:0016569 163 0.010
positive regulation of cell adhesion GO:0045785 80 0.010
divalent metal ion transport GO:0070838 172 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
ear development GO:0043583 200 0.010

Icmt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
disease of cellular proliferation DOID:14566 0 0.014
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014