|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.524
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.448
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.330
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.317
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.296
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.294
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.264
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.263
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.258
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.254
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.242
|
Fly |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.240
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.236
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.235
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.231
|
Mouse Fly |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.227
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.225
|
Fly |
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.222
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.217
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.207
|
Mouse |
|
|
telencephalon development
|
GO:0021537 |
186 |
0.204
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.203
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.203
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.201
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.193
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.192
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.186
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.183
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.181
|
Human |
|
|
pallium development
|
GO:0021543 |
120 |
0.180
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.176
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.170
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.156
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.153
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.153
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.148
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.146
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.144
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.143
|
Fly |
|
|
placenta development
|
GO:0001890 |
140 |
0.142
|
Mouse |
|
|
skin development
|
GO:0043588 |
220 |
0.141
|
Mouse |
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.140
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.139
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.138
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.136
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.133
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.130
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.128
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.124
|
Fly |
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.123
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.122
|
Human |
|
|
immune effector process
|
GO:0002252 |
321 |
0.121
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.121
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.121
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.120
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.118
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.117
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.117
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.116
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.116
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.115
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.114
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
83 |
0.114
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.114
|
Human |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.111
|
Fly |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.111
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.111
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.108
|
Human |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.108
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.103
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.100
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.100
|
Fly |
|
|
respiratory system development
|
GO:0060541 |
190 |
0.099
|
Fly |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.099
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.098
|
Human |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.098
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.097
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.097
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.095
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.095
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.094
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.093
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.092
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.092
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.090
|
Human Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.090
|
Human Mouse |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.089
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.089
|
Human Mouse |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.088
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.088
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.088
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.087
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.087
|
Mouse Fly |
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.086
|
|
|
|
negative regulation of alcohol biosynthetic process
|
GO:1902931 |
4 |
0.085
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.084
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.084
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.083
|
Mouse |
|
|
innate immune response
|
GO:0045087 |
157 |
0.083
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.083
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.083
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.083
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.081
|
Human |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.081
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.080
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.080
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.078
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.078
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.076
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.076
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.076
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.076
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.075
|
Fly |
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.075
|
Human Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.075
|
|
|
|
somite development
|
GO:0061053 |
81 |
0.075
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.075
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.074
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.074
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.073
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.073
|
Mouse |
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.072
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.072
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.071
|
Fly |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.070
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.069
|
Mouse |
|
|
palate development
|
GO:0060021 |
76 |
0.069
|
|
|
|
primitive erythrocyte differentiation
|
GO:0060319 |
3 |
0.068
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.067
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.067
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.067
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.067
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.066
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.066
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.066
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.066
|
Human |
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.066
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.066
|
Fly |
|
|
digestive system development
|
GO:0055123 |
200 |
0.065
|
Mouse Fly |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.065
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.065
|
Human |
|
|
dna recombination
|
GO:0006310 |
92 |
0.065
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.064
|
|
|
|
skin morphogenesis
|
GO:0043589 |
38 |
0.064
|
Mouse |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.063
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.063
|
Human |
|
|
regulation of tight junction assembly
|
GO:2000810 |
2 |
0.062
|
Human |
|
|
interleukin 8 secretion
|
GO:0072606 |
3 |
0.062
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.062
|
Human |
|
|
dna endoreduplication
|
GO:0042023 |
4 |
0.061
|
Fly |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.061
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
50 |
0.060
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.059
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.059
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.058
|
Human |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.058
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.058
|
Mouse |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.058
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.058
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.057
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.057
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.057
|
|
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
26 |
0.057
|
|
|
|
mesenchymal cell proliferation
|
GO:0010463 |
44 |
0.057
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.056
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.056
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
49 |
0.056
|
Fly |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.055
|
|
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
37 |
0.055
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.054
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.053
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.053
|
|
|
|
substrate dependent cell migration
|
GO:0006929 |
18 |
0.053
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.053
|
Human |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.053
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.052
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.052
|
Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.052
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
63 |
0.052
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
47 |
0.052
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.051
|
Human |
|
|
cytokine production
|
GO:0001816 |
319 |
0.051
|
Human |
|
|
protein acylation
|
GO:0043543 |
64 |
0.051
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.051
|
Human |
|
|
gland development
|
GO:0048732 |
330 |
0.051
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.051
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.051
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.050
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
45 |
0.050
|
|
|
|
fat soluble vitamin biosynthetic process
|
GO:0042362 |
4 |
0.050
|
Human |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.050
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.050
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.050
|
Mouse Fly |
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.050
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.050
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
13 |
0.050
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.050
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.049
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.049
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.049
|
Mouse |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.048
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.048
|
Fly |
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.048
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.048
|
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.047
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.047
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.047
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.047
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.047
|
|
|
|
retinal blood vessel morphogenesis
|
GO:0061304 |
3 |
0.046
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.046
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.046
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.046
|
Human |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.045
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.045
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.045
|
Human Mouse |
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
22 |
0.045
|
Mouse |
|
|
maintenance of location
|
GO:0051235 |
89 |
0.044
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.044
|
Human |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.044
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.044
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.044
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.044
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.043
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.043
|
Human |
|
|
positive regulation of interleukin 6 secretion
|
GO:2000778 |
1 |
0.043
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.043
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.042
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.042
|
Fly |
|
|
neural crest cell differentiation
|
GO:0014033 |
54 |
0.042
|
Human |
|
|
bone development
|
GO:0060348 |
120 |
0.042
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.041
|
|
|
|
nephron tubule development
|
GO:0072080 |
84 |
0.041
|
|
|
|
anatomical structure maturation
|
GO:0071695 |
49 |
0.040
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.040
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.040
|
Human |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.040
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
59 |
0.040
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.040
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.040
|
Human |
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.039
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.038
|
|
|
|
thrombin receptor signaling pathway
|
GO:0070493 |
2 |
0.038
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
68 |
0.038
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.038
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.038
|
Human |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.038
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.037
|
Human |
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.037
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.037
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.037
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.037
|
Fly |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.037
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.036
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.036
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.036
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.036
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.036
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.036
|
|
|
|
positive regulation of interleukin 8 secretion
|
GO:2000484 |
1 |
0.036
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
4 |
0.036
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.035
|
Human |
|
|
mesonephros development
|
GO:0001823 |
97 |
0.035
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.035
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.035
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.035
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.035
|
|
|
|
diencephalon development
|
GO:0021536 |
63 |
0.035
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.035
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.035
|
Fly |
|
|
response to radiation
|
GO:0009314 |
165 |
0.034
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.034
|
|
|
|
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
|
GO:0014834 |
3 |
0.034
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.034
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.034
|
|
|
|
renal tubule development
|
GO:0061326 |
87 |
0.034
|
Fly |
|
|
spinal cord development
|
GO:0021510 |
81 |
0.034
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
68 |
0.033
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.033
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.033
|
|
|
|
pituitary gland development
|
GO:0021983 |
38 |
0.033
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.033
|
|
|
|
translation
|
GO:0006412 |
93 |
0.033
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.033
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.033
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.033
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.033
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.033
|
|
|
|
branching involved in ureteric bud morphogenesis
|
GO:0001658 |
56 |
0.033
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.033
|
Human |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.033
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
47 |
0.032
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
34 |
0.032
|
Human |
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.032
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.032
|
Human |
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.032
|
|
|
|
norepinephrine transport
|
GO:0015874 |
2 |
0.032
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.032
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.032
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.032
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
46 |
0.032
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.032
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
47 |
0.032
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.032
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.032
|
|
|
|
transepithelial chloride transport
|
GO:0030321 |
4 |
0.032
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.031
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.031
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.031
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.031
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.031
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.031
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.031
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.031
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.031
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.031
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.030
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.030
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.030
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.030
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.030
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.030
|
Human |
|
|
developmental programmed cell death
|
GO:0010623 |
41 |
0.030
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.030
|
Human |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.030
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.030
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.030
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.030
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.030
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.030
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.029
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.029
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.029
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.029
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.029
|
|
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.029
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.029
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.029
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.029
|
Fly |
|
|
embryonic camera type eye development
|
GO:0031076 |
36 |
0.029
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.029
|
|
|
|
face morphogenesis
|
GO:0060325 |
29 |
0.029
|
|
|
|
cell differentiation involved in embryonic placenta development
|
GO:0060706 |
26 |
0.029
|
Mouse |
|
|
regulation of system process
|
GO:0044057 |
200 |
0.029
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.029
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.029
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.029
|
|
|
|
smooth muscle tissue development
|
GO:0048745 |
22 |
0.029
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.029
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
53 |
0.029
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.028
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.028
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.028
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.028
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.028
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.028
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.028
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.028
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.028
|
Fly |
|
|
midgut development
|
GO:0007494 |
4 |
0.028
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.028
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.028
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.027
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.027
|
Human |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.027
|
|
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
22 |
0.027
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.027
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.027
|
Mouse |
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.027
|
|
|
|
neuron projection extension involved in neuron projection guidance
|
GO:1902284 |
14 |
0.027
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
11 |
0.027
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.027
|
Mouse |
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.027
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.027
|
|
|
|
pigmentation
|
GO:0043473 |
71 |
0.027
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
33 |
0.027
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.026
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.026
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
23 |
0.026
|
|
|
|
regulation of phospholipase a2 activity
|
GO:0032429 |
3 |
0.026
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.026
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.026
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.026
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.026
|
Fly |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.026
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.026
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.026
|
Human |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.026
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.026
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.026
|
|
|
|
regulation of acute inflammatory response to non antigenic stimulus
|
GO:0002877 |
2 |
0.026
|
|
|
|
trophoblast giant cell differentiation
|
GO:0060707 |
15 |
0.025
|
Mouse |
|
|
organism emergence from protective structure
|
GO:0071684 |
4 |
0.025
|
|
|
|
positive regulation of acute inflammatory response to non antigenic stimulus
|
GO:0002879 |
2 |
0.025
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.025
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.025
|
Human |
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
27 |
0.025
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.025
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.025
|
|
|
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
15 |
0.025
|
Mouse |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.025
|
|
|
|
neural crest cell migration
|
GO:0001755 |
32 |
0.025
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.025
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.025
|
Human |
|
|
protein targeting
|
GO:0006605 |
143 |
0.025
|
Human |
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.025
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
2 |
0.025
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.025
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.025
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.025
|
|
|
|
hippocampus development
|
GO:0021766 |
52 |
0.024
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.024
|
|
|
|
intestinal epithelial structure maintenance
|
GO:0060729 |
4 |
0.024
|
|
|
|
regulation of keratinocyte proliferation
|
GO:0010837 |
15 |
0.024
|
Human |
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.024
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
41 |
0.024
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
29 |
0.024
|
Mouse |
|
|
regulation of renin secretion into blood stream
|
GO:1900133 |
4 |
0.024
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
53 |
0.024
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.024
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.024
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.024
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.024
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.024
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.023
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.023
|
|
|
|
cardiac muscle cell development
|
GO:0055013 |
39 |
0.023
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.023
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.023
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.023
|
|
|
|
artery development
|
GO:0060840 |
53 |
0.023
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.023
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.023
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.023
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.023
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
20 |
0.023
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
62 |
0.023
|
|
|
|
positive regulation of smooth muscle cell migration
|
GO:0014911 |
4 |
0.023
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
47 |
0.023
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.023
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.023
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.023
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.023
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.023
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.023
|
|
|
|
stem cell division
|
GO:0017145 |
30 |
0.023
|
Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.022
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.022
|
|
|
|
vitamin d biosynthetic process
|
GO:0042368 |
3 |
0.022
|
Human |
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.022
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.022
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
43 |
0.022
|
Human |
|
|
regionalization
|
GO:0003002 |
337 |
0.022
|
Mouse |
|
|
trachea cartilage morphogenesis
|
GO:0060535 |
4 |
0.022
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.022
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.022
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.022
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.022
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.022
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.022
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.021
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.021
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.021
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.021
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.021
|
Human |
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.021
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
18 |
0.021
|
|
|
|
interleukin 6 secretion
|
GO:0072604 |
3 |
0.021
|
|
|
|
keratinocyte proliferation
|
GO:0043616 |
21 |
0.021
|
Human |
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.021
|
Fly |
|
|
trabecula morphogenesis
|
GO:0061383 |
40 |
0.021
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.021
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.021
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.021
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.021
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.021
|
Human |
|
|
renal system process
|
GO:0003014 |
48 |
0.021
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.021
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.021
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.021
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.021
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.021
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.021
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.020
|
|
|
|
endocardial cushion to mesenchymal transition involved in heart valve formation
|
GO:0003199 |
4 |
0.020
|
|
|
|
astrocyte fate commitment
|
GO:0060018 |
4 |
0.020
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.020
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.020
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.020
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.020
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
47 |
0.020
|
|
|
|
endoderm formation
|
GO:0001706 |
20 |
0.020
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.020
|
Human |
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.020
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.020
|
|
