Mus musculus

0 known processes

Ankle2

ankyrin repeat and LEM domain containing 2

(Aliases: 1110001J12Rik,D5Ertd585e,AI661024)

Ankle2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation or removal GO:0070647 207 0.088
modification dependent macromolecule catabolic process GO:0043632 133 0.080
protein ubiquitination GO:0016567 171 0.067
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.066
ubiquitin dependent protein catabolic process GO:0006511 129 0.065
cellular protein catabolic process GO:0044257 155 0.061
protein modification by small protein conjugation GO:0032446 187 0.061
cellular macromolecule catabolic process GO:0044265 206 0.056
macromolecule catabolic process GO:0009057 281 0.053
cellular ketone metabolic process GO:0042180 84 0.052
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
cellular amino acid metabolic process GO:0006520 103 0.044
proteasomal protein catabolic process GO:0010498 98 0.044
regulation of cellular ketone metabolic process GO:0010565 66 0.043
modification dependent protein catabolic process GO:0019941 133 0.041
cellular amine metabolic process GO:0044106 44 0.041
amine metabolic process GO:0009308 45 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
histone modification GO:0016570 159 0.037
regulation of organelle organization GO:0033043 289 0.036
chromatin modification GO:0016568 187 0.032
protein catabolic process GO:0030163 221 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
peptidyl amino acid modification GO:0018193 336 0.030
covalent chromatin modification GO:0016569 163 0.028
ribose phosphate metabolic process GO:0019693 291 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.026
nucleotide metabolic process GO:0009117 332 0.025
membrane organization GO:0061024 245 0.025
Human
chromatin organization GO:0006325 206 0.025
negative regulation of immune system process GO:0002683 209 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
leukocyte differentiation GO:0002521 342 0.024
apoptotic signaling pathway GO:0097190 306 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.022
cytokine production GO:0001816 319 0.022
cation transport GO:0006812 399 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
regulation of cellular catabolic process GO:0031329 242 0.020
methylation GO:0032259 134 0.020
response to oxidative stress GO:0006979 123 0.020
transmembrane transport GO:0055085 412 0.020
mitotic cell cycle GO:0000278 195 0.020
Human
regulation of lymphocyte activation GO:0051249 240 0.020
cation transmembrane transport GO:0098655 266 0.020
dna repair GO:0006281 107 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
negative regulation of molecular function GO:0044092 258 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
regulation of cytokine production GO:0001817 266 0.018
regulation of cell activation GO:0050865 289 0.018
myeloid cell differentiation GO:0030099 233 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
cell type specific apoptotic process GO:0097285 268 0.018
organelle fission GO:0048285 170 0.018
spermatogenesis GO:0007283 284 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
regulation of cell cycle GO:0051726 281 0.018
nucleoside catabolic process GO:0009164 206 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
mitotic cell cycle process GO:1903047 159 0.017
Human
cellular lipid metabolic process GO:0044255 323 0.017
organophosphate catabolic process GO:0046434 232 0.017
immune effector process GO:0002252 321 0.017
positive regulation of protein modification process GO:0031401 299 0.017
Human
engulfment of apoptotic cell GO:0043652 3 0.017
homeostasis of number of cells GO:0048872 210 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.016
purine containing compound metabolic process GO:0072521 311 0.016
response to radiation GO:0009314 165 0.016
dna metabolic process GO:0006259 303 0.016
response to organonitrogen compound GO:0010243 246 0.016
lymphocyte differentiation GO:0030098 242 0.016
cytoplasmic transport GO:0016482 234 0.016
ion transmembrane transport GO:0034220 361 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
male gamete generation GO:0048232 285 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
cellular response to cytokine stimulus GO:0071345 189 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
stem cell differentiation GO:0048863 268 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
regulation of hydrolase activity GO:0051336 246 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
positive regulation of cell death GO:0010942 224 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
regulation of defense response GO:0031347 233 0.015
heterocycle catabolic process GO:0046700 280 0.015
carbohydrate metabolic process GO:0005975 230 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
cellular homeostasis GO:0019725 240 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
regionalization GO:0003002 337 0.014
nucleoside metabolic process GO:0009116 246 0.014
regulation of system process GO:0044057 200 0.014
regulation of cellular response to stress GO:0080135 159 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
negative regulation of protein modification process GO:0031400 163 0.014
cellular response to lipid GO:0071396 145 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
intracellular protein transport GO:0006886 204 0.014
response to acid chemical GO:0001101 111 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
purine nucleotide catabolic process GO:0006195 211 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
endocytosis GO:0006897 168 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
t cell activation GO:0042110 289 0.013
macromolecule methylation GO:0043414 120 0.013
regulation of chromosome organization GO:0033044 83 0.013
regulation of membrane potential GO:0042391 192 0.013
aromatic compound catabolic process GO:0019439 286 0.013
defense response to other organism GO:0098542 197 0.013
germ cell development GO:0007281 185 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
nuclear division GO:0000280 158 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
negative regulation of nervous system development GO:0051961 156 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
regulation of protein localization GO:0032880 231 0.012
muscle cell differentiation GO:0042692 261 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
regulation of cell cycle process GO:0010564 160 0.012
blood vessel morphogenesis GO:0048514 285 0.012
anatomical structure homeostasis GO:0060249 145 0.012
maintenance of location GO:0051235 89 0.012
purine containing compound catabolic process GO:0072523 213 0.012
action potential GO:0001508 78 0.012
chromosome segregation GO:0007059 48 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
nucleotide catabolic process GO:0009166 217 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
regulation of kinase activity GO:0043549 249 0.012
nitrogen compound transport GO:0071705 271 0.012
ossification GO:0001503 216 0.012
forebrain development GO:0030900 302 0.012
organelle localization GO:0051640 179 0.012
neural tube development GO:0021915 160 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
microtubule based process GO:0007017 236 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
regulation of protein catabolic process GO:0042176 108 0.012
protein processing GO:0016485 163 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
inflammatory response GO:0006954 244 0.012
negative regulation of cell cycle GO:0045786 123 0.012
mapk cascade GO:0000165 281 0.012
ras protein signal transduction GO:0007265 77 0.012
regulation of transferase activity GO:0051338 263 0.012
protein maturation GO:0051604 176 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
inorganic ion transmembrane transport GO:0098660 234 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
lipid biosynthetic process GO:0008610 179 0.011
response to organic cyclic compound GO:0014070 198 0.011
negative regulation of cell development GO:0010721 169 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
multicellular organism growth GO:0035264 161 0.011
glycerolipid metabolic process GO:0046486 122 0.011
heart morphogenesis GO:0003007 178 0.011
neuronal action potential GO:0019228 54 0.011
protein alkylation GO:0008213 81 0.011
regulation of t cell activation GO:0050863 170 0.011
stem cell development GO:0048864 219 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
regulation of intracellular transport GO:0032386 159 0.011
divalent inorganic cation transport GO:0072511 178 0.011
fertilization GO:0009566 127 0.011
regulation of feeding behavior GO:0060259 3 0.011
regulation of response to wounding GO:1903034 189 0.011
endomembrane system organization GO:0010256 147 0.011
Human
regulation of protein kinase activity GO:0045859 232 0.011
multicellular organismal signaling GO:0035637 91 0.011
b cell activation GO:0042113 161 0.011
cell adhesion GO:0007155 329 0.011
gland development GO:0048732 330 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
regulation of hormone levels GO:0010817 211 0.011
regulation of mapk cascade GO:0043408 248 0.011
glucose homeostasis GO:0042593 128 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.010
regulation of secretion GO:0051046 274 0.010
response to light stimulus GO:0009416 135 0.010
response to growth factor GO:0070848 198 0.010
spermatid development GO:0007286 108 0.010
regulation of cellular component size GO:0032535 121 0.010
adult behavior GO:0030534 135 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
regulation of protein transport GO:0051223 163 0.010
response to inorganic substance GO:0010035 96 0.010
lateral inhibition GO:0046331 1 0.010
innate immune response GO:0045087 157 0.010
sensory perception GO:0007600 245 0.010
cellularization GO:0007349 1 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010

Ankle2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.021
central nervous system disease DOID:331 0 0.011