Mus musculus

3 known processes

Mcm10

minichromosome maintenance deficient 10 (S. cerevisiae)

(Aliases: C79164,2410041F14Rik,AU018508,C330019M07Rik)

Mcm10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 107 0.554
dna metabolic process GO:0006259 303 0.413
cellular response to dna damage stimulus GO:0006974 207 0.257
metaphase plate congression GO:0051310 2 0.240
chromatin modification GO:0016568 187 0.134
negative regulation of cell cycle phase transition GO:1901988 48 0.125
cellular ketone metabolic process GO:0042180 84 0.120
cellular amino acid metabolic process GO:0006520 103 0.119
double strand break repair GO:0006302 48 0.100
heterocycle catabolic process GO:0046700 280 0.095
regulation of cellular ketone metabolic process GO:0010565 66 0.089
organic cyclic compound catabolic process GO:1901361 295 0.088
female meiosis chromosome segregation GO:0016321 1 0.087
regulation of cellular amino acid metabolic process GO:0006521 5 0.085
dna endoreduplication GO:0042023 4 0.077
organophosphate catabolic process GO:0046434 232 0.072
organelle assembly GO:0070925 177 0.068
meiotic nuclear division GO:0007126 115 0.068
macromolecule catabolic process GO:0009057 281 0.068
cellular amine metabolic process GO:0044106 44 0.059
immune effector process GO:0002252 321 0.058
mitotic cell cycle GO:0000278 195 0.057
nucleoside phosphate metabolic process GO:0006753 338 0.055
male meiosis GO:0007140 37 0.053
cellular macromolecule catabolic process GO:0044265 206 0.052
cytokine production GO:0001816 319 0.052
nucleobase containing small molecule metabolic process GO:0055086 352 0.052
ribonucleoside catabolic process GO:0042454 206 0.051
purine nucleotide metabolic process GO:0006163 302 0.049
response to radiation GO:0009314 165 0.049
regulation of cellular amine metabolic process GO:0033238 20 0.048
dna catabolic process endonucleolytic GO:0000737 15 0.048
cell division GO:0051301 120 0.048
adaptive immune response GO:0002250 155 0.047
organonitrogen compound catabolic process GO:1901565 264 0.047
mitotic chromosome condensation GO:0007076 1 0.047
regulation of cell cycle process GO:0010564 160 0.047
ribonucleoside metabolic process GO:0009119 245 0.047
histone threonine phosphorylation GO:0035405 1 0.046
regulation of organelle organization GO:0033043 289 0.045
meiotic cell cycle GO:0051321 122 0.045
response to cell cycle checkpoint signaling GO:0072396 1 0.044
regulation of cell cycle GO:0051726 281 0.042
nucleoside triphosphate metabolic process GO:0009141 230 0.041
oxidation reduction process GO:0055114 342 0.041
humoral immune response GO:0006959 57 0.040
multicellular organism growth GO:0035264 161 0.040
protein catabolic process GO:0030163 221 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.038
lymphocyte mediated immunity GO:0002449 139 0.038
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.037
production of molecular mediator of immune response GO:0002440 103 0.037
aromatic compound catabolic process GO:0019439 286 0.037
chromatin organization GO:0006325 206 0.036
cellular homeostasis GO:0019725 240 0.036
leukocyte mediated immunity GO:0002443 174 0.036
negative regulation of cell cycle GO:0045786 123 0.036
amine metabolic process GO:0009308 45 0.036
negative regulation of cellular component organization GO:0051129 194 0.036
microtubule based process GO:0007017 236 0.035
microtubule cytoskeleton organization GO:0000226 157 0.035
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.034
chromosome segregation GO:0007059 48 0.034
leukocyte differentiation GO:0002521 342 0.034
regulation of cytokine production GO:0001817 266 0.034
purine containing compound metabolic process GO:0072521 311 0.033
regulation of protein localization GO:0032880 231 0.033
dna biosynthetic process GO:0071897 22 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
meiotic cell cycle process GO:1903046 77 0.032
wound healing GO:0042060 157 0.031
nucleoside triphosphate catabolic process GO:0009143 205 0.030
actin cytoskeleton organization GO:0030036 220 0.030
centrosome separation GO:0051299 4 0.030
negative regulation of cellular amine metabolic process GO:0033239 1 0.030
purine nucleoside catabolic process GO:0006152 205 0.030
endomembrane system organization GO:0010256 147 0.030
mitochondrion organization GO:0007005 134 0.030
myosin filament assembly GO:0031034 2 0.029
regulation of reactive oxygen species metabolic process GO:2000377 40 0.029
nucleoside metabolic process GO:0009116 246 0.029
mitotic cell cycle process GO:1903047 159 0.029
dna dependent dna replication GO:0006261 24 0.029
organelle fission GO:0048285 170 0.028
macromolecule methylation GO:0043414 120 0.028
response to organonitrogen compound GO:0010243 246 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.028
dna replication GO:0006260 52 0.028
histone modification GO:0016570 159 0.027
cation transport GO:0006812 399 0.027
cellular response to organonitrogen compound GO:0071417 145 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
establishment of meiotic spindle orientation GO:0051296 1 0.027
nucleoside monophosphate catabolic process GO:0009125 59 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
dna catabolic process exonucleolytic GO:0000738 3 0.026
regulation of lymphocyte mediated immunity GO:0002706 84 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
reactive oxygen species metabolic process GO:0072593 84 0.026
regulation of cellular component size GO:0032535 121 0.025
maintenance of location GO:0051235 89 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
dephosphorylation GO:0016311 129 0.025
calcium ion transport GO:0006816 159 0.025
regulation of t cell activation GO:0050863 170 0.025
regulation of cell cycle phase transition GO:1901987 77 0.024
cellular protein complex assembly GO:0043623 116 0.024
nucleoside monophosphate metabolic process GO:0009123 85 0.024
divalent inorganic cation transport GO:0072511 178 0.024
nucleoside catabolic process GO:0009164 206 0.024
folic acid containing compound metabolic process GO:0006760 3 0.024
regulation of cell division GO:0051302 76 0.024
dna conformation change GO:0071103 37 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
leukocyte proliferation GO:0070661 172 0.024
regulation of cell activation GO:0050865 289 0.024
b cell activation GO:0042113 161 0.024
cellular response to cytokine stimulus GO:0071345 189 0.024
establishment of organelle localization GO:0051656 122 0.023
myosin filament organization GO:0031033 3 0.023
blood vessel morphogenesis GO:0048514 285 0.023
purine nucleotide catabolic process GO:0006195 211 0.023
microtubule nucleation GO:0007020 2 0.023
immunoglobulin mediated immune response GO:0016064 69 0.023
striated muscle myosin thick filament assembly GO:0071688 1 0.022
protein ubiquitination GO:0016567 171 0.022
regulation of adaptive immune response GO:0002819 90 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
t cell activation GO:0042110 289 0.022
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.022
cell cycle checkpoint GO:0000075 47 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
regulation of mitotic cell cycle GO:0007346 126 0.022
negative regulation of organelle organization GO:0010639 90 0.022
gland development GO:0048732 330 0.022
meiotic dna repair synthesis GO:0000711 4 0.021
regulation of secretion GO:0051046 274 0.021
positive regulation of cell cycle process GO:0090068 61 0.021
positive regulation of cell development GO:0010720 237 0.021
positive regulation of cell cycle GO:0045787 92 0.021
dna packaging GO:0006323 30 0.021
b cell mediated immunity GO:0019724 71 0.020
regulation of chromosome organization GO:0033044 83 0.020
development of primary sexual characteristics GO:0045137 143 0.020
cellular lipid metabolic process GO:0044255 323 0.020
lymphocyte differentiation GO:0030098 242 0.020
gonad development GO:0008406 141 0.020
cellular ion homeostasis GO:0006873 165 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.019
wnt signaling pathway GO:0016055 188 0.019
reciprocal meiotic recombination GO:0007131 16 0.019
mitotic sister chromatid cohesion GO:0007064 1 0.019
nuclear division GO:0000280 158 0.019
cellular component assembly involved in morphogenesis GO:0010927 139 0.019
peptidyl amino acid modification GO:0018193 336 0.019
histone h3 k9 acetylation GO:0043970 5 0.019
regulation of cellular response to stress GO:0080135 159 0.019
dna catabolic process GO:0006308 19 0.019
spindle assembly involved in female meiosis GO:0007056 3 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
regulation of mitotic cell cycle phase transition GO:1901990 73 0.018
divalent metal ion transport GO:0070838 172 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
energy derivation by oxidation of organic compounds GO:0015980 77 0.018
centrosome duplication GO:0051298 16 0.018
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.018
organic acid biosynthetic process GO:0016053 86 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
dna damage response signal transduction resulting in transcription GO:0042772 2 0.018
regulation of anatomical structure size GO:0090066 178 0.018
histone lysine methylation GO:0034968 50 0.018
organelle localization GO:0051640 179 0.018
response to lipopolysaccharide GO:0032496 128 0.017
centrosome cycle GO:0007098 23 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
positive regulation of cell death GO:0010942 224 0.017
apoptotic signaling pathway GO:0097190 306 0.017
regulation of cell cycle g2 m phase transition GO:1902749 10 0.017
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.017
protein oligomerization GO:0051259 67 0.017
ribonucleoside monophosphate catabolic process GO:0009158 57 0.017
nucleotide metabolic process GO:0009117 332 0.017
generation of precursor metabolites and energy GO:0006091 103 0.017
rho protein signal transduction GO:0007266 32 0.017
purine nucleoside monophosphate catabolic process GO:0009128 58 0.017
leukocyte migration GO:0050900 124 0.017
placenta development GO:0001890 140 0.017
membrane organization GO:0061024 245 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
cellular response to biotic stimulus GO:0071216 92 0.017
modification dependent macromolecule catabolic process GO:0043632 133 0.017
nucleotide catabolic process GO:0009166 217 0.016
t cell proliferation GO:0042098 120 0.016
ras protein signal transduction GO:0007265 77 0.016
hepaticobiliary system development GO:0061008 67 0.016
regulation of defense response GO:0031347 233 0.016
positive regulation of nervous system development GO:0051962 221 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
methylation GO:0032259 134 0.015
dna recombination GO:0006310 92 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
female sex differentiation GO:0046660 84 0.015
cellular amino acid catabolic process GO:0009063 25 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
covalent chromatin modification GO:0016569 163 0.015
neuroblast fate commitment GO:0014017 1 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
astral microtubule organization GO:0030953 3 0.015
regulation of cytoskeleton organization GO:0051493 122 0.015
cytoplasmic transport GO:0016482 234 0.015
cellular protein catabolic process GO:0044257 155 0.015
negative regulation of mitotic cell cycle GO:0045930 58 0.015
regulation of t cell proliferation GO:0042129 92 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
rhythmic process GO:0048511 174 0.014
sister chromatid segregation GO:0000819 20 0.014
lipid biosynthetic process GO:0008610 179 0.014
regulation of mitosis GO:0007088 29 0.014
male gamete generation GO:0048232 285 0.014
response to light stimulus GO:0009416 135 0.014
regulation of membrane potential GO:0042391 192 0.014
sister chromatid cohesion GO:0007062 12 0.014
mapk cascade GO:0000165 281 0.014
transmission of nerve impulse GO:0019226 76 0.014
skeletal system morphogenesis GO:0048705 203 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
positive regulation of protein modification process GO:0031401 299 0.013
small molecule catabolic process GO:0044282 71 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.013
lymphocyte proliferation GO:0046651 164 0.013
b cell activation involved in immune response GO:0002312 50 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
centrosome organization GO:0051297 26 0.013
regulation of neuron differentiation GO:0045664 281 0.013
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.013
lymphocyte activation involved in immune response GO:0002285 93 0.013
multicellular organismal signaling GO:0035637 91 0.013
atp metabolic process GO:0046034 75 0.013
development of primary female sexual characteristics GO:0046545 73 0.013
myeloid cell differentiation GO:0030099 233 0.013
cellular response to abiotic stimulus GO:0071214 56 0.012
liver development GO:0001889 66 0.012
anatomical structure homeostasis GO:0060249 145 0.012
regulation of system process GO:0044057 200 0.012
protein methylation GO:0006479 81 0.012
sensory perception GO:0007600 245 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
cell activation involved in immune response GO:0002263 126 0.012
meiosis i GO:0007127 60 0.012
regulation of cell size GO:0008361 72 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
regulation of mapk cascade GO:0043408 248 0.012
myeloid leukocyte activation GO:0002274 83 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
cytokine metabolic process GO:0042107 71 0.012
genetic imprinting GO:0071514 27 0.012
peptidyl serine modification GO:0018209 83 0.012
regulation of response to wounding GO:1903034 189 0.012
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.012
innate immune response GO:0045087 157 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
endocytosis GO:0006897 168 0.011
translesion synthesis GO:0019985 1 0.011
male sex differentiation GO:0046661 109 0.011
cellular chemical homeostasis GO:0055082 215 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
rna processing GO:0006396 105 0.011
negative regulation of immune system process GO:0002683 209 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regulation of dendritic cell cytokine production GO:0002730 2 0.011
regulation of asymmetric cell division GO:0009786 4 0.011
regulation of production of molecular mediator of immune response GO:0002700 65 0.011
t cell differentiation GO:0030217 174 0.011
regulation of protein kinase activity GO:0045859 232 0.011
synapsis GO:0007129 34 0.011
activation of immune response GO:0002253 138 0.011
muscle tissue development GO:0060537 308 0.011
somatic diversification of immune receptors via somatic mutation GO:0002566 8 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
fertilization GO:0009566 127 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
somatic diversification of immune receptors GO:0002200 53 0.011
atp catabolic process GO:0006200 55 0.011
protein polymerization GO:0051258 57 0.011
spindle assembly involved in mitosis GO:0090307 4 0.011
cleavage furrow formation GO:0036089 2 0.011
anion transport GO:0006820 177 0.011
male gonad development GO:0008584 88 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
cellular respiration GO:0045333 38 0.011
blastocyst development GO:0001824 80 0.011
regulation of transferase activity GO:0051338 263 0.010
chromatin mediated maintenance of transcription GO:0048096 2 0.010
regulation of lymphocyte differentiation GO:0045619 107 0.010
muscle cell differentiation GO:0042692 261 0.010
protein localization to organelle GO:0033365 185 0.010
negative regulation of cytokine production GO:0001818 84 0.010
spermatogenesis GO:0007283 284 0.010
regulation of cell motility GO:2000145 236 0.010
regulation of actin filament based process GO:0032970 99 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
immunoglobulin production GO:0002377 73 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010
organic acid catabolic process GO:0016054 51 0.010
protein acylation GO:0043543 64 0.010
peptidyl lysine modification GO:0018205 77 0.010
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.010
regulation of cellular catabolic process GO:0031329 242 0.010
cellular lipid catabolic process GO:0044242 52 0.010
response to organic cyclic compound GO:0014070 198 0.010
skeletal system development GO:0001501 356 0.010

Mcm10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.462
disease of anatomical entity DOID:7 0 0.462
anemia DOID:2355 0 0.301
hematopoietic system disease DOID:74 0 0.301
bone marrow disease DOID:4961 0 0.301
aplastic anemia DOID:12449 0 0.301
congenital hypoplastic anemia DOID:1342 0 0.301
fanconi s anemia DOID:13636 0 0.052
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.022
cancer DOID:162 0 0.022
thoracic cancer DOID:5093 0 0.022
nervous system disease DOID:863 0 0.018
breast cancer DOID:1612 0 0.011