Mus musculus

2 known processes

Lclat1

lysocardiolipin acyltransferase 1

(Aliases: Alcat1,Lycat,Gm91,AI181996,Agpat8)

Lclat1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lipid metabolic process GO:0044255 323 0.116
Mouse
cellular amino acid metabolic process GO:0006520 103 0.116
dephosphorylation GO:0016311 129 0.074
amine metabolic process GO:0009308 45 0.069
endomembrane system organization GO:0010256 147 0.060
regulation of cellular amino acid metabolic process GO:0006521 5 0.059
fatty acid metabolic process GO:0006631 121 0.057
monocarboxylic acid metabolic process GO:0032787 191 0.055
organic acid catabolic process GO:0016054 51 0.055
oxidation reduction process GO:0055114 342 0.054
nucleoside phosphate metabolic process GO:0006753 338 0.053
regulation of cellular ketone metabolic process GO:0010565 66 0.051
cellular amine metabolic process GO:0044106 44 0.050
nucleobase containing small molecule metabolic process GO:0055086 352 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
small molecule catabolic process GO:0044282 71 0.045
regulation of cellular amine metabolic process GO:0033238 20 0.044
positive regulation of protein modification process GO:0031401 299 0.043
response to organonitrogen compound GO:0010243 246 0.042
transmembrane transport GO:0055085 412 0.041
carboxylic acid catabolic process GO:0046395 51 0.038
cellular lipid catabolic process GO:0044242 52 0.038
purine nucleoside metabolic process GO:0042278 241 0.038
heterocycle catabolic process GO:0046700 280 0.038
regulation of organelle organization GO:0033043 289 0.037
glycerolipid metabolic process GO:0046486 122 0.036
Mouse
regulation of membrane potential GO:0042391 192 0.035
mapk cascade GO:0000165 281 0.034
organophosphate catabolic process GO:0046434 232 0.034
carbohydrate derivative biosynthetic process GO:1901137 183 0.034
negative regulation of intracellular signal transduction GO:1902532 167 0.033
cellular ketone metabolic process GO:0042180 84 0.033
cellular nitrogen compound catabolic process GO:0044270 280 0.032
organelle localization GO:0051640 179 0.032
ion transmembrane transport GO:0034220 361 0.032
nucleoside metabolic process GO:0009116 246 0.032
ribose phosphate metabolic process GO:0019693 291 0.032
purine nucleotide metabolic process GO:0006163 302 0.032
small gtpase mediated signal transduction GO:0007264 97 0.032
membrane organization GO:0061024 245 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
regulation of mapk cascade GO:0043408 248 0.031
lipid biosynthetic process GO:0008610 179 0.031
myeloid cell differentiation GO:0030099 233 0.031
cytokine production GO:0001816 319 0.031
cation transmembrane transport GO:0098655 266 0.030
microtubule based process GO:0007017 236 0.030
maintenance of location GO:0051235 89 0.029
ras protein signal transduction GO:0007265 77 0.029
lipid catabolic process GO:0016042 69 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
homeostasis of number of cells GO:0048872 210 0.029
regulation of cell activation GO:0050865 289 0.028
carbohydrate derivative catabolic process GO:1901136 231 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
regionalization GO:0003002 337 0.028
nucleotide metabolic process GO:0009117 332 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
organonitrogen compound catabolic process GO:1901565 264 0.027
cation transport GO:0006812 399 0.027
mitochondrion organization GO:0007005 134 0.027
cation homeostasis GO:0055080 212 0.026
organic cyclic compound catabolic process GO:1901361 295 0.026
cellular ion homeostasis GO:0006873 165 0.026
phospholipid metabolic process GO:0006644 87 0.026
actin cytoskeleton organization GO:0030036 220 0.026
regulation of hydrolase activity GO:0051336 246 0.025
cellular metal ion homeostasis GO:0006875 151 0.025
regulation of cellular catabolic process GO:0031329 242 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.025
apoptotic signaling pathway GO:0097190 306 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
monocarboxylic acid catabolic process GO:0072329 27 0.024
positive regulation of organelle organization GO:0010638 128 0.024
spermatogenesis GO:0007283 284 0.024
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.024
cellular response to organonitrogen compound GO:0071417 145 0.023
protein localization to organelle GO:0033365 185 0.023
glycerophospholipid metabolic process GO:0006650 71 0.023
protein localization to membrane GO:0072657 108 0.023
negative regulation of phosphorylation GO:0042326 166 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
sulfur compound metabolic process GO:0006790 100 0.023
protein oligomerization GO:0051259 67 0.023
organic hydroxy compound metabolic process GO:1901615 203 0.023
acylglycerol metabolic process GO:0006639 55 0.023
Mouse
metal ion homeostasis GO:0055065 189 0.023
small molecule biosynthetic process GO:0044283 132 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
leukocyte differentiation GO:0002521 342 0.023
regulation of secretion by cell GO:1903530 249 0.022
nucleoside catabolic process GO:0009164 206 0.022
cellular protein catabolic process GO:0044257 155 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
fatty acid catabolic process GO:0009062 25 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
protein ubiquitination GO:0016567 171 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
carboxylic acid biosynthetic process GO:0046394 86 0.021
cellular homeostasis GO:0019725 240 0.021
intracellular protein transport GO:0006886 204 0.021
rho protein signal transduction GO:0007266 32 0.021
male gamete generation GO:0048232 285 0.021
cellular component assembly involved in morphogenesis GO:0010927 139 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
purine containing compound metabolic process GO:0072521 311 0.021
divalent inorganic cation homeostasis GO:0072507 138 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
macromolecule catabolic process GO:0009057 281 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
endocytosis GO:0006897 168 0.020
lipid localization GO:0010876 126 0.020
peptidyl amino acid modification GO:0018193 336 0.020
regulation of protein localization GO:0032880 231 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
regulation of cytokine production GO:0001817 266 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
modification dependent macromolecule catabolic process GO:0043632 133 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
anion transport GO:0006820 177 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
lipid modification GO:0030258 65 0.019
organophosphate biosynthetic process GO:0090407 122 0.019
immune effector process GO:0002252 321 0.019
myeloid leukocyte differentiation GO:0002573 119 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
negative regulation of protein modification process GO:0031400 163 0.019
regulation of cellular response to stress GO:0080135 159 0.019
response to peptide hormone GO:0043434 127 0.019
mitotic cell cycle GO:0000278 195 0.018
organelle fission GO:0048285 170 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
calcium ion homeostasis GO:0055074 127 0.018
nucleotide catabolic process GO:0009166 217 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
ossification GO:0001503 216 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
divalent metal ion transport GO:0070838 172 0.018
response to insulin GO:0032868 100 0.018
neuron death GO:0070997 154 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
cellular chemical homeostasis GO:0055082 215 0.018
protein catabolic process GO:0030163 221 0.018
positive regulation of growth GO:0045927 104 0.018
nuclear division GO:0000280 158 0.018
cellular carbohydrate metabolic process GO:0044262 119 0.018
response to organic cyclic compound GO:0014070 198 0.018
regulation of t cell activation GO:0050863 170 0.017
divalent inorganic cation transport GO:0072511 178 0.017
response to peptide GO:1901652 136 0.017
sensory perception GO:0007600 245 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
response to growth factor GO:0070848 198 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
cytoplasmic transport GO:0016482 234 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
regulation of map kinase activity GO:0043405 120 0.017
gland development GO:0048732 330 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
regulation of homeostatic process GO:0032844 182 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
transmission of nerve impulse GO:0019226 76 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
synapse organization GO:0050808 125 0.016
action potential GO:0001508 78 0.016
macromolecule glycosylation GO:0043413 55 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
macromolecule deacylation GO:0098732 37 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
regulation of defense response GO:0031347 233 0.016
cell adhesion GO:0007155 329 0.016
rab protein signal transduction GO:0032482 1 0.016
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.016
glycoprotein metabolic process GO:0009100 116 0.016
skeletal system development GO:0001501 356 0.016
triglyceride metabolic process GO:0006641 51 0.016
inorganic cation transmembrane transport GO:0098662 207 0.015
purine containing compound catabolic process GO:0072523 213 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
plasma membrane organization GO:0007009 90 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
regulation of body fluid levels GO:0050878 162 0.015
glucose homeostasis GO:0042593 128 0.015
renal system development GO:0072001 225 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
aromatic compound catabolic process GO:0019439 286 0.015
regulation of ossification GO:0030278 112 0.015
cell type specific apoptotic process GO:0097285 268 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
forebrain development GO:0030900 302 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
covalent chromatin modification GO:0016569 163 0.015
rhodopsin mediated signaling pathway GO:0016056 4 0.015
regulation of anatomical structure size GO:0090066 178 0.015
tube formation GO:0035148 140 0.015
chemotaxis GO:0006935 247 0.015
organic acid biosynthetic process GO:0016053 86 0.015
regulation of cell projection organization GO:0031344 206 0.015
muscle cell differentiation GO:0042692 261 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
t cell activation GO:0042110 289 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
nucleoside monophosphate metabolic process GO:0009123 85 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
cell division GO:0051301 120 0.014
anatomical structure homeostasis GO:0060249 145 0.014
glycerolipid biosynthetic process GO:0045017 50 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
regulation of ion transport GO:0043269 215 0.014
regulation of cell motility GO:2000145 236 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
positive regulation of cell development GO:0010720 237 0.014
blood circulation GO:0008015 195 0.014
glycosylation GO:0070085 62 0.014
protein glycosylation GO:0006486 55 0.014
wnt signaling pathway GO:0016055 188 0.014
response to inorganic substance GO:0010035 96 0.014
cofactor metabolic process GO:0051186 80 0.014
alcohol metabolic process GO:0006066 116 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
membrane depolarization GO:0051899 64 0.014
compound eye development GO:0048749 1 0.014
regulation of multi organism process GO:0043900 111 0.014
muscle tissue development GO:0060537 308 0.014
regulation of secretion GO:0051046 274 0.013
membrane lipid biosynthetic process GO:0046467 32 0.013
energy derivation by oxidation of organic compounds GO:0015980 77 0.013
regulation of neuron death GO:1901214 134 0.013
camera type eye development GO:0043010 266 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
inflammatory response GO:0006954 244 0.013
microtubule based movement GO:0007018 84 0.013
regulation of system process GO:0044057 200 0.013
striated muscle tissue development GO:0014706 293 0.013
protein localization to nucleus GO:0034504 121 0.013
regulation of transferase activity GO:0051338 263 0.013
dna metabolic process GO:0006259 303 0.013
cellular response to insulin stimulus GO:0032869 78 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
negative regulation of mapk cascade GO:0043409 65 0.013
chromatin modification GO:0016568 187 0.013
response to extracellular stimulus GO:0009991 127 0.013
regulation of endocytosis GO:0030100 69 0.013
multicellular organism growth GO:0035264 161 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
multicellular organismal signaling GO:0035637 91 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
developmental maturation GO:0021700 193 0.013
innate immune response GO:0045087 157 0.013
fat cell differentiation GO:0045444 160 0.013
circulatory system process GO:0003013 197 0.013
calcium ion transport GO:0006816 159 0.013
nitrogen compound transport GO:0071705 271 0.012
lymphocyte proliferation GO:0046651 164 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
protein deacetylation GO:0006476 32 0.012
nuclear envelope organization GO:0006998 11 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
positive regulation of cell activation GO:0050867 158 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
chromatin organization GO:0006325 206 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
regulation of cell migration GO:0030334 219 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
sequestering of metal ion GO:0051238 19 0.012
regulation of kinase activity GO:0043549 249 0.012
muscle system process GO:0003012 141 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
neural tube development GO:0021915 160 0.012
hindbrain development GO:0030902 128 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
kidney development GO:0001822 213 0.012
regulation of neuron differentiation GO:0045664 281 0.012
protein targeting GO:0006605 143 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
nuclear transport GO:0051169 139 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
regulation of protein kinase activity GO:0045859 232 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
actin filament organization GO:0007015 113 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
regulation of cellular response to growth factor stimulus GO:0090287 82 0.012
regulation of transmembrane transport GO:0034762 128 0.012
urogenital system development GO:0001655 261 0.011
acetylcholine transport GO:0015870 2 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
cellular response to peptide GO:1901653 92 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
leukocyte homeostasis GO:0001776 79 0.011
meiotic nuclear division GO:0007126 115 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
cellular protein complex assembly GO:0043623 116 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
fatty acid transmembrane transport GO:1902001 1 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
mitochondrion distribution GO:0048311 4 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
positive regulation of secretion GO:0051047 130 0.011
regulation of cell division GO:0051302 76 0.011
carbohydrate metabolic process GO:0005975 230 0.011
heart contraction GO:0060047 93 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
sterol transport GO:0015918 38 0.011
synaptic transmission GO:0007268 329 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
regulation of transporter activity GO:0032409 57 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
biomineral tissue development GO:0031214 64 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
oocyte axis specification GO:0007309 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
locomotory behavior GO:0007626 195 0.011
sequestering of calcium ion GO:0051208 18 0.011
negative regulation of defense response GO:0031348 77 0.011
mitotic cell cycle process GO:1903047 159 0.011
mitotic cytokinesis GO:0000281 4 0.011
lipid oxidation GO:0034440 29 0.011
organelle assembly GO:0070925 177 0.011
organic hydroxy compound transport GO:0015850 93 0.011
regulation of cell adhesion GO:0030155 154 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
response to lipopolysaccharide GO:0032496 128 0.011
negative regulation of immune system process GO:0002683 209 0.011
calcium ion transmembrane transport GO:0070588 85 0.011
cellular modified amino acid metabolic process GO:0006575 63 0.011
wound healing GO:0042060 157 0.011
atp metabolic process GO:0046034 75 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
negative regulation of cytokine production GO:0001818 84 0.011
regulation of fat cell differentiation GO:0045598 81 0.010
sensory organ morphogenesis GO:0090596 242 0.010
anion transmembrane transport GO:0098656 71 0.010
regulation of protein catabolic process GO:0042176 108 0.010
cardiocyte differentiation GO:0035051 87 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
embryonic epithelial tube formation GO:0001838 130 0.010
regulation of response to wounding GO:1903034 189 0.010
protein localization to plasma membrane GO:0072659 57 0.010
very long chain fatty acid catabolic process GO:0042760 2 0.010
regulation of chromosome organization GO:0033044 83 0.010
regulation of actin filament based process GO:0032970 99 0.010
lymphocyte homeostasis GO:0002260 64 0.010
lymphocyte differentiation GO:0030098 242 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
leukocyte proliferation GO:0070661 172 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
protein homooligomerization GO:0051260 43 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
methylation GO:0032259 134 0.010
cell maturation GO:0048469 127 0.010

Lclat1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.024
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
musculoskeletal system disease DOID:17 0 0.020
disease of cellular proliferation DOID:14566 0 0.018
cardiovascular system disease DOID:1287 0 0.014
central nervous system disease DOID:331 0 0.012
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
immune system disease DOID:2914 0 0.011
sensory system disease DOID:0050155 0 0.011
connective tissue disease DOID:65 0 0.011
bone disease DOID:0080001 0 0.011
carbohydrate metabolic disorder DOID:2978 0 0.010
inherited metabolic disorder DOID:655 0 0.010