Mus musculus

57 known processes

Trpa1

transient receptor potential cation channel, subfamily A, member 1

(Aliases: Anktm1)

Trpa1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
lymphocyte mediated immunity GO:0002449 139 0.088
immune effector process GO:0002252 321 0.077
regulation of cellular ketone metabolic process GO:0010565 66 0.063
cation transport GO:0006812 399 0.060
leukocyte mediated immunity GO:0002443 174 0.054
cellular amino acid metabolic process GO:0006520 103 0.053
regulation of secretion by cell GO:1903530 249 0.053
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.053
positive regulation of cellular amine metabolic process GO:0033240 5 0.052
cytokine production GO:0001816 319 0.047
apoptotic signaling pathway GO:0097190 306 0.045
regulation of cellular amine metabolic process GO:0033238 20 0.044
cellular ketone metabolic process GO:0042180 84 0.044
regulation of secretion GO:0051046 274 0.043
negative regulation of cell proliferation GO:0008285 296 0.039
cellular response to cytokine stimulus GO:0071345 189 0.037
positive regulation of cell death GO:0010942 224 0.037
cellular lipid metabolic process GO:0044255 323 0.036
membrane organization GO:0061024 245 0.035
g protein coupled receptor signaling pathway GO:0007186 243 0.034
regulation of cell activation GO:0050865 289 0.031
regulation of anatomical structure size GO:0090066 178 0.031
organonitrogen compound biosynthetic process GO:1901566 192 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
amine metabolic process GO:0009308 45 0.030
negative regulation of cell development GO:0010721 169 0.030
inorganic cation transmembrane transport GO:0098662 207 0.029
response to lipopolysaccharide GO:0032496 128 0.029
sulfur compound metabolic process GO:0006790 100 0.028
macromolecule catabolic process GO:0009057 281 0.027
negative regulation of immune system process GO:0002683 209 0.027
cellular response to lipid GO:0071396 145 0.026
stem cell differentiation GO:0048863 268 0.025
inflammatory response GO:0006954 244 0.025
regulation of defense response GO:0031347 233 0.025
regulation of leukocyte mediated immunity GO:0002703 104 0.025
production of molecular mediator of immune response GO:0002440 103 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
innate immune response GO:0045087 157 0.024
peptidyl amino acid modification GO:0018193 336 0.024
nitrogen compound transport GO:0071705 271 0.024
inorganic ion transmembrane transport GO:0098660 234 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
regulation of response to wounding GO:1903034 189 0.023
hematopoietic progenitor cell differentiation GO:0002244 143 0.023
regulation of lymphocyte mediated immunity GO:0002706 84 0.023
positive regulation of transforming growth factor beta secretion GO:2001203 1 0.023
positive regulation of secretion by cell GO:1903532 114 0.022
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.022
mapk cascade GO:0000165 281 0.022
oxidation reduction process GO:0055114 342 0.022
negative regulation of protein metabolic process GO:0051248 282 0.022
fat cell differentiation GO:0045444 160 0.022
cytokine secretion GO:0050663 72 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
peptidyl tyrosine phosphorylation GO:0018108 143 0.022
synaptic transmission GO:0007268 329 0.022
fertilization GO:0009566 127 0.021
fat soluble vitamin biosynthetic process GO:0042362 4 0.021
muscle tissue development GO:0060537 308 0.021
positive regulation of apoptotic process GO:0043065 217 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
regulation of cell cycle GO:0051726 281 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
purine containing compound metabolic process GO:0072521 311 0.020
sensory perception GO:0007600 245 0.020
positive regulation of secretion GO:0051047 130 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
stem cell development GO:0048864 219 0.020
spermatogenesis GO:0007283 284 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
defense response to bacterium GO:0042742 119 0.019
male gamete generation GO:0048232 285 0.019
respiratory system development GO:0060541 190 0.019
cell type specific apoptotic process GO:0097285 268 0.019
lipid biosynthetic process GO:0008610 179 0.019
urogenital system development GO:0001655 261 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.018
adaptive immune response GO:0002250 155 0.018
cellular amine metabolic process GO:0044106 44 0.018
intracellular protein transport GO:0006886 204 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
mesodermal cell migration GO:0008078 4 0.018
cellular chemical homeostasis GO:0055082 215 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
circulatory system process GO:0003013 197 0.018
maintenance of location GO:0051235 89 0.018
cell fate commitment GO:0045165 210 0.018
regulation of cell motility GO:2000145 236 0.018
protein secretion GO:0009306 111 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.017
leukocyte activation involved in immune response GO:0002366 126 0.017
regulation of protein transport GO:0051223 163 0.017
transmembrane transport GO:0055085 412 0.017
glycoprotein metabolic process GO:0009100 116 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
leukocyte migration GO:0050900 124 0.017
protein ubiquitination GO:0016567 171 0.017
muscle cell differentiation GO:0042692 261 0.017
cation transmembrane transport GO:0098655 266 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.017
cellular alcohol biosynthetic process GO:0044108 3 0.017
divalent metal ion transport GO:0070838 172 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.016
ossification GO:0001503 216 0.016
digestive system development GO:0055123 200 0.016
somatotropin secreting cell differentiation GO:0060126 4 0.016
regulation of neuron differentiation GO:0045664 281 0.016
t cell activation GO:0042110 289 0.016
regulation of cell cycle process GO:0010564 160 0.016
peptidyl tyrosine modification GO:0018212 145 0.016
exocytosis GO:0006887 121 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
positive regulation of cell development GO:0010720 237 0.016
protein processing GO:0016485 163 0.016
protein catabolic process GO:0030163 221 0.016
erk1 and erk2 cascade GO:0070371 77 0.016
leukocyte proliferation GO:0070661 172 0.016
regulation of feeding behavior GO:0060259 3 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
chromatin organization GO:0006325 206 0.015
cell activation involved in immune response GO:0002263 126 0.015
alcohol metabolic process GO:0006066 116 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
spermatid development GO:0007286 108 0.015
striated muscle tissue development GO:0014706 293 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
positive regulation of nervous system development GO:0051962 221 0.015
macromolecule methylation GO:0043414 120 0.015
organic anion transport GO:0015711 137 0.015
inner ear receptor cell differentiation GO:0060113 61 0.015
multi multicellular organism process GO:0044706 109 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
regulation of cell migration GO:0030334 219 0.015
regulation of system process GO:0044057 200 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
camera type eye development GO:0043010 266 0.015
response to inorganic substance GO:0010035 96 0.015
antimicrobial peptide biosynthetic process GO:0002777 2 0.015
positive regulation of immune effector process GO:0002699 107 0.014
regulation of organelle organization GO:0033043 289 0.014
methylation GO:0032259 134 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
endocytosis GO:0006897 168 0.014
regulation of exocytosis GO:0017157 61 0.014
ion transmembrane transport GO:0034220 361 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
nucleotide metabolic process GO:0009117 332 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
skeletal muscle organ development GO:0060538 163 0.014
regulation of cytokine secretion GO:0050707 61 0.014
nucleoside metabolic process GO:0009116 246 0.014
regulation of mapk cascade GO:0043408 248 0.014
lymphocyte differentiation GO:0030098 242 0.014
chromatin modification GO:0016568 187 0.014
response to acid chemical GO:0001101 111 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
regulation of tube size GO:0035150 57 0.014
regulation of intracellular transport GO:0032386 159 0.014
midgut development GO:0007494 4 0.014
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.014
Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
regulation of chromosome organization GO:0033044 83 0.013
single fertilization GO:0007338 82 0.013
hormone secretion GO:0046879 128 0.013
response to organonitrogen compound GO:0010243 246 0.013
small molecule biosynthetic process GO:0044283 132 0.013
regulation of angiogenesis GO:0045765 81 0.013
positive regulation of cytokine production GO:0001819 174 0.013
defense response to other organism GO:0098542 197 0.013
positive regulation of protein modification process GO:0031401 299 0.013
lymphocyte activation involved in immune response GO:0002285 93 0.013
regulation of membrane potential GO:0042391 192 0.013
cellular homeostasis GO:0019725 240 0.013
renal system development GO:0072001 225 0.013
mesenchymal cell differentiation GO:0048762 107 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
stem cell maintenance GO:0019827 130 0.013
respiratory tube development GO:0030323 167 0.013
carbohydrate metabolic process GO:0005975 230 0.013
axonogenesis GO:0007409 274 0.013
negative regulation of defense response GO:0031348 77 0.013
germ cell development GO:0007281 185 0.013
intracellular mrna localization GO:0008298 4 0.013
angiogenesis GO:0001525 201 0.013
heterocycle catabolic process GO:0046700 280 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
cell killing GO:0001906 67 0.013
vitamin d biosynthetic process GO:0042368 3 0.012
homeostasis of number of cells GO:0048872 210 0.012
aromatic compound catabolic process GO:0019439 286 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
epithelial cell development GO:0002064 159 0.012
leukocyte differentiation GO:0002521 342 0.012
regulation of binding GO:0051098 111 0.012
lung development GO:0030324 164 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
steroid metabolic process GO:0008202 119 0.012
response to oxidative stress GO:0006979 123 0.012
regulation of transferase activity GO:0051338 263 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
anion transport GO:0006820 177 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
regulation of striated muscle cell differentiation GO:0051153 81 0.012
regulation of muscle tissue development GO:1901861 97 0.012
bmp signaling pathway GO:0030509 93 0.012
glucose homeostasis GO:0042593 128 0.012
regulation of cell adhesion GO:0030155 154 0.012
regulation of protein localization GO:0032880 231 0.012
protein maturation GO:0051604 176 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
lipid transport GO:0006869 98 0.012
amide transport GO:0042886 138 0.012
response to organic cyclic compound GO:0014070 198 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
regulation of protein maturation GO:1903317 96 0.012
myeloid cell differentiation GO:0030099 233 0.012
cell adhesion GO:0007155 329 0.012
cofactor metabolic process GO:0051186 80 0.012
developmental cell growth GO:0048588 84 0.012
b cell activation GO:0042113 161 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
purine nucleoside metabolic process GO:0042278 241 0.011
kidney development GO:0001822 213 0.011
organic acid transport GO:0015849 101 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
blood circulation GO:0008015 195 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
leukocyte mediated cytotoxicity GO:0001909 62 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
carboxylic acid transport GO:0046942 100 0.011
sequestering of metal ion GO:0051238 19 0.011
regulation of production of molecular mediator of immune response GO:0002700 65 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
sensory perception of pain GO:0019233 47 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
antimicrobial peptide production GO:0002775 2 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
interspecies interaction between organisms GO:0044419 83 0.011
cytoplasmic transport GO:0016482 234 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
regulation of transforming growth factor beta secretion GO:2001201 1 0.011
lymphocyte proliferation GO:0046651 164 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
carbohydrate homeostasis GO:0033500 128 0.011
neural tube development GO:0021915 160 0.011
regulation of neuron projection development GO:0010975 169 0.011
retina development in camera type eye GO:0060041 119 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
positive regulation of protein transport GO:0051222 93 0.011
immunoglobulin production GO:0002377 73 0.011
b cell mediated immunity GO:0019724 71 0.011
regulation of cytokine production GO:0001817 266 0.011
purine nucleotide metabolic process GO:0006163 302 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
nuclear division GO:0000280 158 0.010
regulation of adaptive immune response GO:0002819 90 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
cell growth GO:0016049 130 0.010
regulation of cell size GO:0008361 72 0.010
secondary alcohol metabolic process GO:1902652 3 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
immunoglobulin mediated immune response GO:0016064 69 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
protein targeting GO:0006605 143 0.010
epithelial cell proliferation GO:0050673 174 0.010
chemotaxis GO:0006935 247 0.010
atp metabolic process GO:0046034 75 0.010
response to drug GO:0042493 75 0.010
regulation of multi organism process GO:0043900 111 0.010
sclerotome development GO:0061056 4 0.010
plasma membrane organization GO:0007009 90 0.010
cellular protein complex assembly GO:0043623 116 0.010

Trpa1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.019
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.018
retinal disease DOID:5679 0 0.013
eye disease DOID:5614 0 0.013
disease of metabolism DOID:0014667 0 0.012