Mus musculus

15 known processes

Mdm1

transformed mouse 3T3 cell double minute 1

(Aliases: Arrd2,Mdm-1)

Mdm1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle assembly GO:0070925 177 0.191
cilium morphogenesis GO:0060271 102 0.186
cilium assembly GO:0042384 81 0.145
regulation of cellular amino acid metabolic process GO:0006521 5 0.100
dna metabolic process GO:0006259 303 0.093
regulation of cellular amine metabolic process GO:0033238 20 0.087
cellular amino acid metabolic process GO:0006520 103 0.074
cellular amine metabolic process GO:0044106 44 0.074
amine metabolic process GO:0009308 45 0.073
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.070
positive regulation of protein modification process GO:0031401 299 0.068
male gamete generation GO:0048232 285 0.068
positive regulation of cellular amine metabolic process GO:0033240 5 0.066
regulation of cellular ketone metabolic process GO:0010565 66 0.061
dna repair GO:0006281 107 0.061
spermatogenesis GO:0007283 284 0.060
microtubule based process GO:0007017 236 0.058
cellular component assembly involved in morphogenesis GO:0010927 139 0.053
regulation of transferase activity GO:0051338 263 0.052
chromatin organization GO:0006325 206 0.052
regulation of organelle organization GO:0033043 289 0.051
mitotic cell cycle GO:0000278 195 0.050
response to radiation GO:0009314 165 0.050
dna recombination GO:0006310 92 0.048
cellular ketone metabolic process GO:0042180 84 0.048
purine nucleotide metabolic process GO:0006163 302 0.048
protein catabolic process GO:0030163 221 0.047
cellular response to dna damage stimulus GO:0006974 207 0.047
chromatin modification GO:0016568 187 0.046
regulation of protein kinase activity GO:0045859 232 0.045
peptidyl amino acid modification GO:0018193 336 0.044
nucleoside phosphate catabolic process GO:1901292 222 0.043
regulation of kinase activity GO:0043549 249 0.042
eye photoreceptor cell development GO:0042462 31 0.042
regulation of cell cycle GO:0051726 281 0.040
mitotic cell cycle process GO:1903047 159 0.039
protein ubiquitination GO:0016567 171 0.038
ras protein signal transduction GO:0007265 77 0.038
eye photoreceptor cell differentiation GO:0001754 41 0.037
nuclear division GO:0000280 158 0.037
regulation of cell cycle process GO:0010564 160 0.037
organelle localization GO:0051640 179 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.036
apoptotic signaling pathway GO:0097190 306 0.036
regulation of protein serine threonine kinase activity GO:0071900 157 0.035
protein modification by small protein conjugation GO:0032446 187 0.035
development of primary sexual characteristics GO:0045137 143 0.035
microtubule based movement GO:0007018 84 0.035
maintenance of location GO:0051235 89 0.035
fertilization GO:0009566 127 0.034
microtubule cytoskeleton organization GO:0000226 157 0.033
covalent chromatin modification GO:0016569 163 0.033
multicellular organism growth GO:0035264 161 0.033
ribonucleotide metabolic process GO:0009259 291 0.032
purine containing compound catabolic process GO:0072523 213 0.032
regulation of cellular catabolic process GO:0031329 242 0.032
macromolecule catabolic process GO:0009057 281 0.032
regulation of apoptotic signaling pathway GO:2001233 197 0.031
microtubule organizing center organization GO:0031023 28 0.031
meiotic cell cycle GO:0051321 122 0.031
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
cellular protein complex assembly GO:0043623 116 0.030
sensory organ morphogenesis GO:0090596 242 0.030
regulation of chromosome organization GO:0033044 83 0.029
positive regulation of protein phosphorylation GO:0001934 242 0.029
purine containing compound metabolic process GO:0072521 311 0.029
regulation of cell activation GO:0050865 289 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
protein modification by small protein conjugation or removal GO:0070647 207 0.028
ribose phosphate metabolic process GO:0019693 291 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.027
organelle fission GO:0048285 170 0.027
glycosyl compound metabolic process GO:1901657 246 0.027
photoreceptor cell differentiation GO:0046530 52 0.027
spermatid development GO:0007286 108 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
leukocyte differentiation GO:0002521 342 0.026
cell division GO:0051301 120 0.026
response to light stimulus GO:0009416 135 0.026
homeostasis of number of cells GO:0048872 210 0.026
negative regulation of cell cycle GO:0045786 123 0.026
organonitrogen compound catabolic process GO:1901565 264 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
glycosyl compound catabolic process GO:1901658 206 0.025
nucleotide metabolic process GO:0009117 332 0.025
regulation of protein localization GO:0032880 231 0.025
germ cell development GO:0007281 185 0.025
smoothened signaling pathway GO:0007224 105 0.025
microtubule nucleation GO:0007020 2 0.025
establishment of organelle localization GO:0051656 122 0.024
spindle assembly involved in mitosis GO:0090307 4 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
male meiosis GO:0007140 37 0.024
positive regulation of transferase activity GO:0051347 167 0.024
histone methylation GO:0016571 71 0.024
negative regulation of molecular function GO:0044092 258 0.024
purine nucleoside metabolic process GO:0042278 241 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
cellular nitrogen compound catabolic process GO:0044270 280 0.023
positive regulation of protein kinase activity GO:0045860 144 0.023
meiotic nuclear division GO:0007126 115 0.023
cation transport GO:0006812 399 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
aromatic compound catabolic process GO:0019439 286 0.023
intrinsic apoptotic signaling pathway GO:0097193 132 0.023
establishment or maintenance of cell polarity GO:0007163 86 0.023
regulation of cell projection organization GO:0031344 206 0.023
positive regulation of cellular catabolic process GO:0031331 148 0.023
macromolecule methylation GO:0043414 120 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.022
camera type eye development GO:0043010 266 0.022
endocytosis GO:0006897 168 0.022
spermatid differentiation GO:0048515 115 0.022
neural tube development GO:0021915 160 0.022
protein localization to organelle GO:0033365 185 0.021
wnt signaling pathway GO:0016055 188 0.021
nucleoside metabolic process GO:0009116 246 0.021
regulation of cell division GO:0051302 76 0.021
skin development GO:0043588 220 0.021
meiosis i GO:0007127 60 0.021
photoreceptor cell development GO:0042461 40 0.021
positive regulation of cell death GO:0010942 224 0.021
membrane organization GO:0061024 245 0.021
regulation of hydrolase activity GO:0051336 246 0.021
organic cyclic compound catabolic process GO:1901361 295 0.020
b cell activation GO:0042113 161 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
histone modification GO:0016570 159 0.020
response to organonitrogen compound GO:0010243 246 0.020
centrosome organization GO:0051297 26 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
single fertilization GO:0007338 82 0.020
lymphocyte differentiation GO:0030098 242 0.020
regulation of intracellular transport GO:0032386 159 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
transmembrane transport GO:0055085 412 0.020
morphogenesis of embryonic epithelium GO:0016331 159 0.020
methylation GO:0032259 134 0.020
positive regulation of organelle organization GO:0010638 128 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.019
cell fate commitment GO:0045165 210 0.019
development of primary male sexual characteristics GO:0046546 88 0.019
locomotory behavior GO:0007626 195 0.019
regulation of cytoskeleton organization GO:0051493 122 0.019
intracellular protein transport GO:0006886 204 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
regulation of microtubule based process GO:0032886 52 0.019
rho protein signal transduction GO:0007266 32 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
response to organic cyclic compound GO:0014070 198 0.019
cytoplasmic transport GO:0016482 234 0.019
endomembrane system organization GO:0010256 147 0.018
negative regulation of protein modification process GO:0031400 163 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
actin cytoskeleton organization GO:0030036 220 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.018
positive regulation of kinase activity GO:0033674 155 0.018
positive regulation of nervous system development GO:0051962 221 0.018
cell adhesion GO:0007155 329 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
neural tube formation GO:0001841 108 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
embryonic epithelial tube formation GO:0001838 130 0.018
immune effector process GO:0002252 321 0.018
neural precursor cell proliferation GO:0061351 121 0.018
digestive system development GO:0055123 200 0.018
nucleotide catabolic process GO:0009166 217 0.018
regulation of anatomical structure size GO:0090066 178 0.017
regulation of cell cycle phase transition GO:1901987 77 0.017
anatomical structure homeostasis GO:0060249 145 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
negative regulation of immune system process GO:0002683 209 0.017
regulation of binding GO:0051098 111 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
double strand break repair GO:0006302 48 0.017
cellular homeostasis GO:0019725 240 0.017
heterocycle catabolic process GO:0046700 280 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
intraciliary transport GO:0042073 9 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
skeletal system development GO:0001501 356 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
nucleoside catabolic process GO:0009164 206 0.016
regulation of chromatin modification GO:1903308 57 0.016
compound eye development GO:0048749 1 0.016
peptidyl lysine modification GO:0018205 77 0.016
regulation of proteolysis GO:0030162 164 0.016
cellular response to lipid GO:0071396 145 0.016
nucleoside monophosphate metabolic process GO:0009123 85 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
protein processing GO:0016485 163 0.016
chemotaxis GO:0006935 247 0.016
cell cycle g1 s phase transition GO:0044843 57 0.016
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
protein acylation GO:0043543 64 0.016
leukocyte mediated immunity GO:0002443 174 0.016
asymmetric neuroblast division GO:0055059 1 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
cell type specific apoptotic process GO:0097285 268 0.016
protein maturation GO:0051604 176 0.016
gonad development GO:0008406 141 0.016
gland development GO:0048732 330 0.016
primary neural tube formation GO:0014020 95 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
forebrain development GO:0030900 302 0.015
rna processing GO:0006396 105 0.015
response to oxidative stress GO:0006979 123 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.015
sensory perception GO:0007600 245 0.015
cation transmembrane transport GO:0098655 266 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
muscle cell differentiation GO:0042692 261 0.015
digestive tract development GO:0048565 190 0.015
protein alkylation GO:0008213 81 0.015
nitrogen compound transport GO:0071705 271 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
histone acetylation GO:0016573 41 0.015
cell activation involved in immune response GO:0002263 126 0.015
myeloid cell differentiation GO:0030099 233 0.015
cellular protein catabolic process GO:0044257 155 0.015
cytokine production GO:0001816 319 0.015
establishment of protein localization to organelle GO:0072594 118 0.014
tube formation GO:0035148 140 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
cellular lipid metabolic process GO:0044255 323 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
male meiosis i GO:0007141 16 0.014
peptidyl serine modification GO:0018209 83 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
protein targeting GO:0006605 143 0.014
mitotic cytokinesis GO:0000281 4 0.014
regulation of membrane potential GO:0042391 192 0.014
retina development in camera type eye GO:0060041 119 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
multi multicellular organism process GO:0044706 109 0.014
innate immune response GO:0045087 157 0.014
striated muscle tissue development GO:0014706 293 0.014
regionalization GO:0003002 337 0.014
attachment of spindle microtubules to kinetochore GO:0008608 4 0.014
ear development GO:0043583 200 0.014
peptidyl serine phosphorylation GO:0018105 74 0.014
muscle tissue development GO:0060537 308 0.013
meiotic cell cycle process GO:1903046 77 0.013
chromosome segregation GO:0007059 48 0.013
negative regulation of organelle organization GO:0010639 90 0.013
regulation of mapk cascade GO:0043408 248 0.013
cytokinetic process GO:0032506 2 0.013
epithelial cell proliferation GO:0050673 174 0.013
epithelial tube formation GO:0072175 130 0.013
t cell activation GO:0042110 289 0.013
microtubule polymerization or depolymerization GO:0031109 26 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
response to inorganic substance GO:0010035 96 0.013
positive regulation of chromosome organization GO:2001252 33 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.013
dna conformation change GO:0071103 37 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
tube closure GO:0060606 91 0.013
respiratory system development GO:0060541 190 0.013
cytoskeleton dependent intracellular transport GO:0030705 50 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
response to growth factor GO:0070848 198 0.013
lung development GO:0030324 164 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
divalent inorganic cation transport GO:0072511 178 0.013
positive regulation of proteolysis GO:0045862 85 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
regulation of chromatin organization GO:1902275 57 0.013
regulation of protein transport GO:0051223 163 0.013
respiratory tube development GO:0030323 167 0.012
double strand break repair via homologous recombination GO:0000724 21 0.012
positive regulation of immune effector process GO:0002699 107 0.012
nucleus localization GO:0051647 20 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
inflammatory response GO:0006954 244 0.012
regulation of cytokine production GO:0001817 266 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
organophosphate catabolic process GO:0046434 232 0.012
protein polymerization GO:0051258 57 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
regulation of body fluid levels GO:0050878 162 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
mitochondrion organization GO:0007005 134 0.012
glucose homeostasis GO:0042593 128 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
axonogenesis GO:0007409 274 0.012
asymmetric stem cell division GO:0098722 3 0.012
skeletal system morphogenesis GO:0048705 203 0.012
regulation of neuron differentiation GO:0045664 281 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
nuclear transport GO:0051169 139 0.012
ribonucleoside monophosphate catabolic process GO:0009158 57 0.012
cognition GO:0050890 149 0.012
regulation of defense response GO:0031347 233 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
adult behavior GO:0030534 135 0.012
skeletal muscle organ development GO:0060538 163 0.012
cellular chemical homeostasis GO:0055082 215 0.012
regulation of cellular response to stress GO:0080135 159 0.012
male gonad development GO:0008584 88 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
multicellular organismal signaling GO:0035637 91 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of protein processing GO:0070613 96 0.012
blastocyst development GO:0001824 80 0.011
lymphocyte apoptotic process GO:0070227 54 0.011
positive regulation of cell cycle GO:0045787 92 0.011
positive regulation of growth GO:0045927 104 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
dna replication independent nucleosome assembly GO:0006336 1 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
stem cell differentiation GO:0048863 268 0.011
regulation of cellular component size GO:0032535 121 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
determination of left right symmetry GO:0007368 80 0.011
cellularization GO:0007349 1 0.011
response to lipopolysaccharide GO:0032496 128 0.011
male sex differentiation GO:0046661 109 0.011
neural tube closure GO:0001843 90 0.011
intracellular mrna localization GO:0008298 4 0.011
regulation of chromosome segregation GO:0051983 21 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
centrosome cycle GO:0007098 23 0.011
protein autophosphorylation GO:0046777 61 0.011
blood vessel morphogenesis GO:0048514 285 0.011
ossification GO:0001503 216 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
gastrulation GO:0007369 116 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
ameboidal type cell migration GO:0001667 128 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
regulation of dna recombination GO:0000018 34 0.011
positive regulation of cell development GO:0010720 237 0.011
nuclear import GO:0051170 95 0.011
regulation of hormone levels GO:0010817 211 0.011
oxidation reduction process GO:0055114 342 0.011
adult locomotory behavior GO:0008344 91 0.011
wound healing GO:0042060 157 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.011
protein methylation GO:0006479 81 0.010
microtubule based transport GO:0010970 50 0.010
protein import into nucleus GO:0006606 95 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
divalent metal ion transport GO:0070838 172 0.010
regulation of histone modification GO:0031056 56 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
protein localization to nucleus GO:0034504 121 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
response to acid chemical GO:0001101 111 0.010
fat cell differentiation GO:0045444 160 0.010
positive regulation of cell activation GO:0050867 158 0.010
protein import GO:0017038 101 0.010
anion transport GO:0006820 177 0.010
tissue homeostasis GO:0001894 115 0.010
regulation of lymphocyte mediated immunity GO:0002706 84 0.010
mrna processing GO:0006397 63 0.010

Mdm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.039
disease of anatomical entity DOID:7 0 0.039
sensory system disease DOID:0050155 0 0.025
central nervous system disease DOID:331 0 0.022
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.019
eye and adnexa disease DOID:1492 0 0.018
eye disease DOID:5614 0 0.018
retinal disease DOID:5679 0 0.018
physical disorder DOID:0080015 0 0.011
retinal degeneration DOID:8466 0 0.011