Mus musculus

135 known processes

Pkn1

protein kinase N1

(Aliases: DBK,PRK1,Stk3,F730027O18Rik,Prkcl1,Pkn,PAK1)

Pkn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 44 0.119
nucleoside phosphate metabolic process GO:0006753 338 0.112
ras protein signal transduction GO:0007265 77 0.106
regulation of cellular amine metabolic process GO:0033238 20 0.105
cation transport GO:0006812 399 0.091
nucleobase containing small molecule metabolic process GO:0055086 352 0.090
glycosyl compound catabolic process GO:1901658 206 0.086
cellular amino acid metabolic process GO:0006520 103 0.082
purine ribonucleotide metabolic process GO:0009150 290 0.081
organophosphate catabolic process GO:0046434 232 0.081
cellular ketone metabolic process GO:0042180 84 0.080
amine metabolic process GO:0009308 45 0.077
heterocycle catabolic process GO:0046700 280 0.077
nucleotide metabolic process GO:0009117 332 0.076
aromatic compound catabolic process GO:0019439 286 0.075
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.073
regulation of cellular amino acid metabolic process GO:0006521 5 0.073
nucleotide catabolic process GO:0009166 217 0.072
purine containing compound catabolic process GO:0072523 213 0.072
positive regulation of cellular amine metabolic process GO:0033240 5 0.070
ribose phosphate metabolic process GO:0019693 291 0.069
purine nucleotide metabolic process GO:0006163 302 0.067
purine nucleoside metabolic process GO:0042278 241 0.067
regulation of cellular ketone metabolic process GO:0010565 66 0.067
nucleoside phosphate catabolic process GO:1901292 222 0.066
organonitrogen compound catabolic process GO:1901565 264 0.063
purine ribonucleoside metabolic process GO:0046128 241 0.062
nucleoside catabolic process GO:0009164 206 0.060
gtp catabolic process GO:0006184 143 0.060
purine ribonucleoside catabolic process GO:0046130 205 0.059
ribonucleoside metabolic process GO:0009119 245 0.059
nucleoside metabolic process GO:0009116 246 0.058
carbohydrate derivative catabolic process GO:1901136 231 0.058
ion transmembrane transport GO:0034220 361 0.058
regulation of cellular catabolic process GO:0031329 242 0.056
cellular nitrogen compound catabolic process GO:0044270 280 0.056
ribonucleoside triphosphate catabolic process GO:0009203 199 0.055
ribonucleoside catabolic process GO:0042454 206 0.055
small gtpase mediated signal transduction GO:0007264 97 0.054
glycosyl compound metabolic process GO:1901657 246 0.054
ribonucleotide metabolic process GO:0009259 291 0.054
purine ribonucleotide catabolic process GO:0009154 208 0.053
transmembrane transport GO:0055085 412 0.053
nucleoside triphosphate catabolic process GO:0009143 205 0.053
negative regulation of cellular amine metabolic process GO:0033239 1 0.053
skin development GO:0043588 220 0.052
cytokine production GO:0001816 319 0.052
purine nucleoside catabolic process GO:0006152 205 0.052
anion transport GO:0006820 177 0.051
purine nucleotide catabolic process GO:0006195 211 0.050
purine nucleoside triphosphate catabolic process GO:0009146 203 0.049
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.048
response to organonitrogen compound GO:0010243 246 0.047
gtp metabolic process GO:0046039 144 0.047
lymphocyte proliferation GO:0046651 164 0.047
nucleoside triphosphate metabolic process GO:0009141 230 0.047
organic cyclic compound catabolic process GO:1901361 295 0.047
purine containing compound metabolic process GO:0072521 311 0.046
ribonucleotide catabolic process GO:0009261 208 0.046
membrane organization GO:0061024 245 0.046
regulation of protein kinase activity GO:0045859 232 0.045
guanosine containing compound metabolic process GO:1901068 144 0.044
negative regulation of protein metabolic process GO:0051248 282 0.044
carbohydrate metabolic process GO:0005975 230 0.043
organonitrogen compound biosynthetic process GO:1901566 192 0.041
positive regulation of protein modification process GO:0031401 299 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.040
negative regulation of phosphorus metabolic process GO:0010563 184 0.039
skeletal system development GO:0001501 356 0.039
regulation of protein localization GO:0032880 231 0.038
regulation of hydrolase activity GO:0051336 246 0.038
positive regulation of gtp catabolic process GO:0033126 85 0.037
purine nucleoside triphosphate metabolic process GO:0009144 226 0.037
ribonucleoside triphosphate metabolic process GO:0009199 220 0.037
activation of immune response GO:0002253 138 0.037
cellular lipid metabolic process GO:0044255 323 0.037
cation transmembrane transport GO:0098655 266 0.037
cellular response to organonitrogen compound GO:0071417 145 0.035
immune response activating signal transduction GO:0002757 116 0.035
negative regulation of cell proliferation GO:0008285 296 0.035
actin cytoskeleton organization GO:0030036 220 0.035
Fly
negative regulation of cellular protein metabolic process GO:0032269 247 0.035
peptidyl amino acid modification GO:0018193 336 0.035
Human
gland development GO:0048732 330 0.035
cellular response to lipid GO:0071396 145 0.035
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.034
inflammatory response GO:0006954 244 0.034
immune response regulating signaling pathway GO:0002764 125 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.033
regulation of ion transport GO:0043269 215 0.033
regulation of secretion by cell GO:1903530 249 0.033
regulation of cytokine production GO:0001817 266 0.032
reactive oxygen species metabolic process GO:0072593 84 0.032
cellular component assembly involved in morphogenesis GO:0010927 139 0.032
regulation of nucleoside metabolic process GO:0009118 130 0.032
multicellular organismal homeostasis GO:0048871 164 0.032
regulation of transferase activity GO:0051338 263 0.032
regulation of purine nucleotide catabolic process GO:0033121 122 0.032
regulation of membrane potential GO:0042391 192 0.031
positive regulation of protein phosphorylation GO:0001934 242 0.031
mapk cascade GO:0000165 281 0.031
regulation of purine nucleotide metabolic process GO:1900542 169 0.031
regulation of nucleotide catabolic process GO:0030811 122 0.031
regulation of nucleotide metabolic process GO:0006140 169 0.031
cellular response to cytokine stimulus GO:0071345 189 0.031
muscle cell differentiation GO:0042692 261 0.030
lipid transport GO:0006869 98 0.030
regulation of cellular response to stress GO:0080135 159 0.030
calcium ion transport GO:0006816 159 0.030
positive regulation of cell death GO:0010942 224 0.030
positive regulation of nucleotide catabolic process GO:0030813 88 0.030
organic anion transport GO:0015711 137 0.030
cellular chemical homeostasis GO:0055082 215 0.030
ossification GO:0001503 216 0.030
positive regulation of programmed cell death GO:0043068 218 0.029
guanosine containing compound catabolic process GO:1901069 144 0.029
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
endomembrane system organization GO:0010256 147 0.029
inorganic ion transmembrane transport GO:0098660 234 0.029
positive regulation of gtpase activity GO:0043547 85 0.029
cellular ion homeostasis GO:0006873 165 0.029
myeloid cell differentiation GO:0030099 233 0.028
negative regulation of molecular function GO:0044092 258 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.028
compound eye development GO:0048749 1 0.028
positive regulation of cellular catabolic process GO:0031331 148 0.028
cell adhesion GO:0007155 329 0.028
regulation of gtp catabolic process GO:0033124 113 0.028
metal ion homeostasis GO:0055065 189 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.027
lipid biosynthetic process GO:0008610 179 0.027
cellular homeostasis GO:0019725 240 0.027
lipid localization GO:0010876 126 0.027
leukocyte proliferation GO:0070661 172 0.027
positive regulation of hydrolase activity GO:0051345 148 0.027
regulation of ras protein signal transduction GO:0046578 114 0.026
positive regulation of ras gtpase activity GO:0032320 65 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
sensory organ morphogenesis GO:0090596 242 0.026
dephosphorylation GO:0016311 129 0.026
regulation of neuron differentiation GO:0045664 281 0.026
positive regulation of nucleoside metabolic process GO:0045979 91 0.026
protein modification by small protein conjugation GO:0032446 187 0.026
oxidation reduction process GO:0055114 342 0.026
endocytosis GO:0006897 168 0.025
b cell activation GO:0042113 161 0.025
protein ubiquitination GO:0016567 171 0.025
cation homeostasis GO:0055080 212 0.025
respiratory system development GO:0060541 190 0.025
urogenital system development GO:0001655 261 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.025
negative regulation of phosphate metabolic process GO:0045936 184 0.025
leukocyte activation involved in immune response GO:0002366 126 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.025
organic hydroxy compound transport GO:0015850 93 0.025
monocarboxylic acid metabolic process GO:0032787 191 0.025
regulation of protein transport GO:0051223 163 0.025
respiratory tube development GO:0030323 167 0.024
maintenance of location GO:0051235 89 0.024
cellular response to hormone stimulus GO:0032870 150 0.024
positive regulation of kinase activity GO:0033674 155 0.024
apoptotic signaling pathway GO:0097190 306 0.024
positive regulation of nucleotide metabolic process GO:0045981 114 0.023
cellular metal ion homeostasis GO:0006875 151 0.023
nitrogen compound transport GO:0071705 271 0.023
regulation of ras gtpase activity GO:0032318 88 0.023
regulation of defense response GO:0031347 233 0.023
negative regulation of phosphorylation GO:0042326 166 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
protein processing GO:0016485 163 0.023
response to organic cyclic compound GO:0014070 198 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
regulation of mapk cascade GO:0043408 248 0.023
leukocyte differentiation GO:0002521 342 0.023
myeloid leukocyte differentiation GO:0002573 119 0.023
divalent inorganic cation transport GO:0072511 178 0.023
glycoprotein biosynthetic process GO:0009101 89 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
regulation of cell projection organization GO:0031344 206 0.022
lung development GO:0030324 164 0.022
anatomical structure homeostasis GO:0060249 145 0.022
microtubule based process GO:0007017 236 0.022
lateral inhibition GO:0046331 1 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
protein maturation GO:0051604 176 0.022
divalent inorganic cation homeostasis GO:0072507 138 0.021
muscle cell development GO:0055001 133 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
sulfur compound metabolic process GO:0006790 100 0.021
regulation of cell motility GO:2000145 236 0.021
Human
chromatin organization GO:0006325 206 0.021
Human
defense response to virus GO:0051607 68 0.021
cellular divalent inorganic cation homeostasis GO:0072503 127 0.021
glycoprotein metabolic process GO:0009100 116 0.021
regulation of t cell activation GO:0050863 170 0.021
regulation of organelle organization GO:0033043 289 0.021
t cell proliferation GO:0042098 120 0.021
macromolecule catabolic process GO:0009057 281 0.021
intracellular protein transport GO:0006886 204 0.021
regulation of lymphocyte activation GO:0051249 240 0.020
positive regulation of cell development GO:0010720 237 0.020
camera type eye development GO:0043010 266 0.020
regulation of leukocyte differentiation GO:1902105 159 0.020
male gamete generation GO:0048232 285 0.020
retina development in camera type eye GO:0060041 119 0.020
regulation of secretion GO:0051046 274 0.020
positive regulation of cytokine production GO:0001819 174 0.019
sequestering of calcium ion GO:0051208 18 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
leukocyte migration GO:0050900 124 0.019
response to molecule of bacterial origin GO:0002237 143 0.019
cellular response to lipopolysaccharide GO:0071222 77 0.019
cellular calcium ion homeostasis GO:0006874 119 0.019
negative regulation of protein modification process GO:0031400 163 0.019
regulation of homeostatic process GO:0032844 182 0.019
stem cell differentiation GO:0048863 268 0.019
adaptive immune response GO:0002250 155 0.019
spermatogenesis GO:0007283 284 0.019
striated muscle tissue development GO:0014706 293 0.019
t cell activation GO:0042110 289 0.019
cellular response to dna damage stimulus GO:0006974 207 0.018
gliogenesis GO:0042063 141 0.018
lymphocyte activation involved in immune response GO:0002285 93 0.018
cytokine metabolic process GO:0042107 71 0.018
response to oxidative stress GO:0006979 123 0.018
regulation of b cell activation GO:0050864 81 0.018
chromatin modification GO:0016568 187 0.018
Human
leukocyte mediated immunity GO:0002443 174 0.018
transmission of nerve impulse GO:0019226 76 0.018
innate immune response GO:0045087 157 0.018
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.018
organelle assembly GO:0070925 177 0.018
positive regulation of apoptotic signaling pathway GO:2001235 95 0.018
renal system development GO:0072001 225 0.018
defense response to other organism GO:0098542 197 0.018
regulation of system process GO:0044057 200 0.018
regulation of reactive oxygen species metabolic process GO:2000377 40 0.018
response to inorganic substance GO:0010035 96 0.017
histone modification GO:0016570 159 0.017
Human
digestive system development GO:0055123 200 0.017
calcium ion homeostasis GO:0055074 127 0.017
extracellular structure organization GO:0043062 148 0.017
sequestering of metal ion GO:0051238 19 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
axonogenesis GO:0007409 274 0.017
neuron apoptotic process GO:0051402 142 0.017
response to peptide GO:1901652 136 0.017
regulation of intracellular transport GO:0032386 159 0.017
organic acid transport GO:0015849 101 0.017
reactive nitrogen species metabolic process GO:2001057 0 0.017
regulation of multi organism process GO:0043900 111 0.017
kidney development GO:0001822 213 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
blood circulation GO:0008015 195 0.017
fatty acid metabolic process GO:0006631 121 0.017
synaptic transmission GO:0007268 329 0.017
rho protein signal transduction GO:0007266 32 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
methylation GO:0032259 134 0.017
muscle tissue development GO:0060537 308 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
neuron death GO:0070997 154 0.016
extracellular matrix organization GO:0030198 147 0.016
regulation of cell migration GO:0030334 219 0.016
chemotaxis GO:0006935 247 0.016
meiotic cell cycle GO:0051321 122 0.016
regulation of kinase activity GO:0043549 249 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
response to extracellular stimulus GO:0009991 127 0.016
cellular response to biotic stimulus GO:0071216 92 0.016
lymphocyte differentiation GO:0030098 242 0.016
regulation of t cell proliferation GO:0042129 92 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
forebrain development GO:0030900 302 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
regulation of metal ion transport GO:0010959 106 0.016
striated muscle cell development GO:0055002 125 0.016
skeletal muscle organ development GO:0060538 163 0.016
regulation of cell activation GO:0050865 289 0.016
response to nutrient levels GO:0031667 109 0.016
microtubule cytoskeleton organization GO:0000226 157 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
mitochondrion organization GO:0007005 134 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
action potential GO:0001508 78 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
positive regulation of secretion GO:0051047 130 0.015
immune effector process GO:0002252 321 0.015
response to lipopolysaccharide GO:0032496 128 0.015
multicellular organism growth GO:0035264 161 0.015
positive regulation of map kinase activity GO:0043406 84 0.015
regulation of response to wounding GO:1903034 189 0.015
Fly
small molecule biosynthetic process GO:0044283 132 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
regulation of neuron projection development GO:0010975 169 0.015
dna metabolic process GO:0006259 303 0.015
developmental maturation GO:0021700 193 0.015
regulation of lymphocyte proliferation GO:0050670 117 0.015
interleukin 6 production GO:0032635 58 0.015
actin filament organization GO:0007015 113 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
negative regulation of cell activation GO:0050866 111 0.015
cytoplasmic transport GO:0016482 234 0.015
myotube differentiation GO:0014902 105 0.015
positive regulation of transferase activity GO:0051347 167 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
glycerolipid metabolic process GO:0046486 122 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
homeostasis of number of cells GO:0048872 210 0.014
stem cell development GO:0048864 219 0.014
regulation of anatomical structure size GO:0090066 178 0.014
regulation of interleukin 8 production GO:0032677 3 0.014
negative regulation of immune system process GO:0002683 209 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
epidermis development GO:0008544 187 0.014
lipoprotein metabolic process GO:0042157 43 0.014
response to insulin GO:0032868 100 0.014
monosaccharide metabolic process GO:0005996 106 0.014
macromolecule methylation GO:0043414 120 0.014
regulation of transmembrane transport GO:0034762 128 0.014
carbohydrate homeostasis GO:0033500 128 0.014
rhythmic process GO:0048511 174 0.014
regulation of protein processing GO:0070613 96 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
humoral immune response GO:0006959 57 0.014
anion transmembrane transport GO:0098656 71 0.014
response to radiation GO:0009314 165 0.014
response to peptide hormone GO:0043434 127 0.014
b cell proliferation GO:0042100 53 0.014
positive regulation of secretion by cell GO:1903532 114 0.014
alcohol metabolic process GO:0006066 116 0.014
peptide transport GO:0015833 133 0.014
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
peptidyl serine modification GO:0018209 83 0.014
response to acid chemical GO:0001101 111 0.014
regulation of map kinase activity GO:0043405 120 0.013
negative regulation of lymphocyte activation GO:0051250 91 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
protein localization to organelle GO:0033365 185 0.013
epithelial cell development GO:0002064 159 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
regulation of protein maturation GO:1903317 96 0.013
regulation of endocytosis GO:0030100 69 0.013
plasma membrane organization GO:0007009 90 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
organic acid biosynthetic process GO:0016053 86 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
negative regulation of phagocytosis GO:0050765 4 0.013
regulation of body fluid levels GO:0050878 162 0.013
positive regulation of ion transport GO:0043270 65 0.013
organelle localization GO:0051640 179 0.013
tissue homeostasis GO:0001894 115 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
regulation of hormone levels GO:0010817 211 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
regulation of proteolysis GO:0030162 164 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.013
protein localization to nucleus GO:0034504 121 0.013
regulation of protein secretion GO:0050708 82 0.013
peptidyl serine phosphorylation GO:0018105 74 0.013
divalent metal ion transport GO:0070838 172 0.013
multicellular organismal signaling GO:0035637 91 0.013
regulation of ossification GO:0030278 112 0.013
cell type specific apoptotic process GO:0097285 268 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
fat cell differentiation GO:0045444 160 0.013
protein catabolic process GO:0030163 221 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
glial cell apoptotic process GO:0034349 3 0.013
cell activation involved in immune response GO:0002263 126 0.013
covalent chromatin modification GO:0016569 163 0.013
Human
wound healing GO:0042060 157 0.013
Fly
gonad development GO:0008406 141 0.013
skeletal system morphogenesis GO:0048705 203 0.013
epithelial cell proliferation GO:0050673 174 0.012
b cell activation involved in immune response GO:0002312 50 0.012
protein secretion GO:0009306 111 0.012
protein localization to membrane GO:0072657 108 0.012
interleukin 10 secretion GO:0072608 4 0.012
circulatory system process GO:0003013 197 0.012
nuclear division GO:0000280 158 0.012
positive regulation of innate immune response GO:0045089 80 0.012
regulation of inflammatory response GO:0050727 147 0.012
single organism cell adhesion GO:0098602 156 0.012
carboxylic acid transport GO:0046942 100 0.012
glucose metabolic process GO:0006006 92 0.012
negative regulation of defense response GO:0031348 77 0.012
protein targeting GO:0006605 143 0.012
calcium ion transmembrane transport GO:0070588 85 0.012
wnt signaling pathway GO:0016055 188 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
heart contraction GO:0060047 93 0.012
hexose metabolic process GO:0019318 98 0.012
regulation of interleukin 6 production GO:0032675 55 0.012
appendage development GO:0048736 166 0.012
cellular protein catabolic process GO:0044257 155 0.012
translation GO:0006412 93 0.012
t cell differentiation GO:0030217 174 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.012
neural precursor cell proliferation GO:0061351 121 0.012
response to growth factor GO:0070848 198 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
hormone metabolic process GO:0042445 86 0.012
negative regulation of cellular catabolic process GO:0031330 47 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
connective tissue development GO:0061448 179 0.012
cellular protein complex assembly GO:0043623 116 0.012
cofactor metabolic process GO:0051186 80 0.012
positive regulation of immune effector process GO:0002699 107 0.012
striated muscle myosin thick filament assembly GO:0071688 1 0.012
macromolecule glycosylation GO:0043413 55 0.012
regulation of translation GO:0006417 71 0.012
myosin filament organization GO:0031033 3 0.011
organelle fission GO:0048285 170 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
development of primary sexual characteristics GO:0045137 143 0.011
multi multicellular organism process GO:0044706 109 0.011
heart morphogenesis GO:0003007 178 0.011
negative regulation of organelle organization GO:0010639 90 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
regulation of rho protein signal transduction GO:0035023 71 0.011
positive regulation of b cell activation GO:0050871 49 0.011
negative regulation of proteolysis GO:0045861 74 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
appendage morphogenesis GO:0035107 149 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of feeding behavior GO:0060259 3 0.011
antigen receptor mediated signaling pathway GO:0050851 64 0.011
protein localization to plasma membrane GO:0072659 57 0.011
cytokine biosynthetic process GO:0042089 68 0.011
negative regulation of protein maturation GO:1903318 79 0.011
neuronal action potential GO:0019228 54 0.011
response to oxygen levels GO:0070482 62 0.011
amide transport GO:0042886 138 0.011
lipid catabolic process GO:0016042 69 0.011
fertilization GO:0009566 127 0.011
telencephalon development GO:0021537 186 0.011
cellular response to peptide GO:1901653 92 0.011
protein alkylation GO:0008213 81 0.011
atp metabolic process GO:0046034 75 0.011
spermatid differentiation GO:0048515 115 0.011
tube formation GO:0035148 140 0.011
membrane lipid metabolic process GO:0006643 53 0.011
negative regulation of inflammatory response GO:0050728 61 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
negative regulation of response to wounding GO:1903035 77 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
sensory perception GO:0007600 245 0.011
regulation of neuron death GO:1901214 134 0.011
cell division GO:0051301 120 0.011
response to light stimulus GO:0009416 135 0.011
actomyosin structure organization GO:0031032 56 0.011
rab protein signal transduction GO:0032482 1 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
cell fate commitment GO:0045165 210 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.010
peptidyl lysine modification GO:0018205 77 0.010
positive regulation of organelle organization GO:0010638 128 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
regulation of interleukin 10 secretion GO:2001179 4 0.010
dendrite development GO:0016358 115 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
negative regulation of cell development GO:0010721 169 0.010
negative regulation of protein processing GO:0010955 79 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
notch signaling pathway GO:0007219 71 0.010
negative regulation of growth GO:0045926 99 0.010
glucose transport GO:0015758 56 0.010
digestive tract development GO:0048565 190 0.010
b cell mediated immunity GO:0019724 71 0.010
amino acid transport GO:0006865 61 0.010
regulation of lymphocyte mediated immunity GO:0002706 84 0.010
cellular response to acid chemical GO:0071229 68 0.010
neural tube formation GO:0001841 108 0.010

Pkn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.037
immune system disease DOID:2914 0 0.026
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.020
inherited metabolic disorder DOID:655 0 0.019
hematopoietic system disease DOID:74 0 0.018
central nervous system disease DOID:331 0 0.017
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
musculoskeletal system disease DOID:17 0 0.013