|
|
synaptic transmission
|
GO:0007268 |
329 |
0.515
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.336
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.293
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.264
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.258
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.252
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.238
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.227
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.218
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.214
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.214
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.204
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.202
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.184
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.174
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.173
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.169
|
Human |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.168
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.154
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
35 |
0.153
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.144
|
|
|
|
negative regulation of synaptic vesicle transport
|
GO:1902804 |
3 |
0.138
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.138
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.136
|
Fly |
|
|
chromatin organization
|
GO:0006325 |
206 |
0.134
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.134
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.131
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.127
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.127
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.124
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.124
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.121
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.121
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.117
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.116
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.116
|
Mouse |
|
|
negative regulation of synaptic vesicle exocytosis
|
GO:2000301 |
3 |
0.115
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.114
|
Human |
|
|
adult behavior
|
GO:0030534 |
135 |
0.114
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
3 |
0.114
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.113
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
11 |
0.111
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.111
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.110
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.108
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.107
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.106
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.102
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.102
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.102
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.101
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.099
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.099
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.099
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.099
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.099
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.098
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.098
|
Mouse |
|
|
protein maturation
|
GO:0051604 |
176 |
0.098
|
Human Mouse |
|
|
regionalization
|
GO:0003002 |
337 |
0.098
|
Fly |
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.097
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.096
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.096
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.095
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.095
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
29 |
0.094
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.092
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.091
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.091
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.090
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.090
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.088
|
Mouse |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.088
|
Mouse |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.088
|
Mouse |
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.087
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
13 |
0.085
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.085
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.083
|
Mouse |
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.082
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.082
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.080
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.079
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.079
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.079
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.077
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.075
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.075
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.074
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.074
|
Human |
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.073
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.072
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.072
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.072
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.071
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.070
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.070
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.069
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.069
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.069
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.068
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.068
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.068
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
17 |
0.068
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.067
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.066
|
Fly |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.066
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.065
|
Fly |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.065
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.065
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.065
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.063
|
Human |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.063
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.063
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.062
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.062
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.062
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.061
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.061
|
Mouse |
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.060
|
Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.060
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.059
|
Mouse |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.059
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.059
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.058
|
|
|
|
protein localization to cell junction
|
GO:1902414 |
3 |
0.058
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.058
|
Mouse |
|
|
vesicle localization
|
GO:0051648 |
86 |
0.057
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.057
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.057
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.057
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.057
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.056
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.056
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.056
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.055
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.055
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.055
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.055
|
Mouse |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.054
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.054
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.054
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.054
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.054
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.054
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.053
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.053
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.053
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.052
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.051
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.051
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.051
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.051
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.051
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.050
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.050
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.050
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.050
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.050
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.050
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.050
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.050
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.050
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.049
|
Fly |
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.049
|
|
|
|
positive regulation of protein autophosphorylation
|
GO:0031954 |
4 |
0.049
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.049
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.049
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.049
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.049
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.049
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.049
|
Fly |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.048
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.048
|
Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.048
|
Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.048
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.048
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.048
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.047
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.047
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.047
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.046
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.046
|
Mouse |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.046
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.046
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.046
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.046
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.046
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.046
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.045
|
Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.045
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.045
|
Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.045
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.045
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.044
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.044
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.044
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
57 |
0.044
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.044
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.044
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.044
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.044
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.043
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.043
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.043
|
Human Mouse |
|
|
heart contraction
|
GO:0060047 |
93 |
0.043
|
Mouse |
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.043
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.043
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.043
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.043
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.043
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.043
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.043
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.043
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.043
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.043
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.042
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.042
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.042
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.042
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.042
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.042
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.041
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.041
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.041
|
Mouse |
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.040
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.040
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.040
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.040
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.040
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.040
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.040
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.040
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.040
|
Fly |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.039
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.039
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.039
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.039
|
Fly |
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.039
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.039
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.039
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.039
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.039
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.039
|
Mouse |
|
|
digestive tract development
|
GO:0048565 |
190 |
0.038
|
Zebrafish |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.038
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.038
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.038
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.038
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.038
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.038
|
Fly |
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.038
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.038
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.037
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.037
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.037
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.037
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.037
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.037
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.037
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.037
|
Fly |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.037
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.037
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.036
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.036
|
Fly |
|
|
rhythmic process
|
GO:0048511 |
174 |
0.036
|
Fly |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.036
|
Mouse Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.036
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.036
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.036
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.036
|
Human Mouse |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.036
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.036
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.035
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.035
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.035
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.035
|
Fly |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.035
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.035
|
|
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.035
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.035
|
|
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.035
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.035
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.035
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.035
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.035
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.035
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.034
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.034
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.034
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.034
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.034
|
Mouse |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.034
|
Mouse |
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.034
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.034
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.034
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.034
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.034
|
Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.034
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.034
|
Human |
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.033
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.033
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.033
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.033
|
Mouse |
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.033
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.033
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.033
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.033
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.033
|
|
|
|
activation of meiosis
|
GO:0090427 |
4 |
0.033
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.032
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.032
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.032
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.032
|
Fly |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.032
|
Mouse |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.032
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.032
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.032
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.032
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.031
|
Zebrafish |
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.031
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
1 |
0.031
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.031
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.031
|
Fly |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.031
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.031
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.031
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.030
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.030
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.030
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.030
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.030
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.030
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.030
|
Fly |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.030
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.030
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.030
|
|
|
|
rhodopsin mediated signaling pathway
|
GO:0016056 |
4 |
0.030
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.030
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.030
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.030
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.030
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.030
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.029
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.029
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.029
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.029
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.029
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.029
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.029
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.029
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.028
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.028
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.028
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.028
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.028
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.028
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.028
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.028
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.028
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.028
|
Mouse |
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.028
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.028
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.028
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.028
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.028
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.028
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.028
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.028
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.028
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.028
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.028
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.028
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.027
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.027
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.027
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.027
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.027
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.027
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.027
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
2 |
0.027
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.027
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.027
|
Human Mouse |
|
|
blood coagulation
|
GO:0007596 |
76 |
0.027
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.026
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.026
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.026
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.026
|
Human |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.026
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.026
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.026
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.026
|
Human |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.026
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.026
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.026
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
15 |
0.026
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.026
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.026
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.026
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.025
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.025
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
34 |
0.025
|
Mouse |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.025
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.025
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.025
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.025
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.025
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.025
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.025
|
Fly |
|
|
forebrain development
|
GO:0030900 |
302 |
0.025
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.025
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.025
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.025
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.025
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.025
|
Human |
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.025
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.024
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.024
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.024
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.024
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.024
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.024
|
|
|
|
synaptic transmission gabaergic
|
GO:0051932 |
19 |
0.024
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.024
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.024
|
Fly |
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.024
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.024
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.024
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.023
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.023
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.023
|
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.023
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.023
|
|
|
|
male courtship behavior
|
GO:0008049 |
2 |
0.023
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.023
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.023
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.023
|
|
|
|
rna processing
|
GO:0006396 |
105 |
0.023
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.023
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.023
|
Fly |
|
|
layer formation in cerebral cortex
|
GO:0021819 |
13 |
0.023
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.023
|
|
|
|
positive regulation of t cell anergy
|
GO:0002669 |
4 |
0.023
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.023
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.022
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.022
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.022
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.022
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.022
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.022
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.022
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.022
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.022
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.022
|
Fly |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.022
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.021
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.021
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.021
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.021
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.021
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.021
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.021
|
|
|
|
synaptic vesicle fusion to presynaptic membrane
|
GO:0031629 |
3 |
0.021
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.021
|
|
|
|
activation of meiosis involved in egg activation
|
GO:0060466 |
2 |
0.021
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.021
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.021
|
Human |
|
|
fibronectin dependent thymocyte migration
|
GO:0072681 |
1 |
0.021
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.021
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
26 |
0.021
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.021
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.021
|
Mouse |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.021
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.021
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.021
|
Fly |
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.021
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.020
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.020
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.020
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.020
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.020
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.020
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.020
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
36 |
0.020
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.020
|
Mouse |
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.020
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.020
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.020
|
Fly |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.020
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.020
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.020
|
Fly |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.020
|
|
