Mus musculus

83 known processes

Cxcl10

chemokine (C-X-C motif) ligand 10

(Aliases: gIP-10,INP10,IP10,IP-10,mob-1,Ifi10,CRG-2,C7,Scyb10)

Cxcl10 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to interferon beta GO:0035458 21 0.961
cellular response to cytokine stimulus GO:0071345 189 0.909
Human
regulation of defense response GO:0031347 233 0.841
Mouse
defense response to other organism GO:0098542 197 0.836
cellular response to lipopolysaccharide GO:0071222 77 0.832
Human
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.830
Mouse
innate immune response GO:0045087 157 0.824
immune effector process GO:0002252 321 0.786
defense response to bacterium GO:0042742 119 0.782
Mouse
regulation of cytokine production GO:0001817 266 0.772
Mouse
response to protozoan GO:0001562 28 0.771
interspecies interaction between organisms GO:0044419 83 0.740
Mouse
defense response to virus GO:0051607 68 0.709
positive regulation of defense response GO:0031349 124 0.663
Mouse
cellular response to biotic stimulus GO:0071216 92 0.622
Human
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.586
Mouse
response to molecule of bacterial origin GO:0002237 143 0.584
Human Mouse Rat
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.535
Mouse
defense response to protozoan GO:0042832 25 0.530
t helper 2 cell cytokine production GO:0035745 4 0.464
positive regulation of cytokine production GO:0001819 174 0.441
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.439
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.439
Mouse
cellular response to interferon gamma GO:0071346 25 0.434
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.418
alpha beta t cell activation involved in immune response GO:0002287 31 0.412
cellular response to lipid GO:0071396 145 0.399
Human
pattern recognition receptor signaling pathway GO:0002221 47 0.383
t cell activation involved in immune response GO:0002286 43 0.376
positive regulation of innate immune response GO:0045089 80 0.370
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.364
production of molecular mediator of immune response GO:0002440 103 0.360
regulation of reactive oxygen species metabolic process GO:2000377 40 0.358
Mouse
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.351
Mouse
myeloid cell differentiation GO:0030099 233 0.341
response to interferon beta GO:0035456 22 0.335
regulation of innate immune response GO:0045088 91 0.331
cellular response to molecule of bacterial origin GO:0071219 83 0.330
Human
cytokine production GO:0001816 319 0.320
Mouse
adaptive immune response GO:0002250 155 0.320
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.306
Mouse
regulation of leukocyte mediated immunity GO:0002703 104 0.301
Mouse
cdc42 protein signal transduction GO:0032488 0 0.299
defense response to gram negative bacterium GO:0050829 28 0.293
Mouse
regulation of multi organism process GO:0043900 111 0.286
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.284
regulation of cellular catabolic process GO:0031329 242 0.279
negative regulation of cytokine production GO:0001818 84 0.278
response to lipopolysaccharide GO:0032496 128 0.271
Human Mouse Rat
regulation of protein transport GO:0051223 163 0.268
response to interferon gamma GO:0034341 34 0.261
positive regulation of immune effector process GO:0002699 107 0.260
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.253
leukocyte activation involved in immune response GO:0002366 126 0.251
defense response to gram positive bacterium GO:0050830 50 0.248
regulation of t cell activation GO:0050863 170 0.245
glycosyl compound metabolic process GO:1901657 246 0.244
cytokine mediated signaling pathway GO:0019221 115 0.243
Human
t cell activation GO:0042110 289 0.240
regulation of t helper 2 cell cytokine production GO:2000551 3 0.240
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.238
activation of innate immune response GO:0002218 56 0.236
negative regulation of multi organism process GO:0043901 68 0.233
regulation of defense response to bacterium GO:1900424 3 0.230
Mouse
cell activation involved in immune response GO:0002263 126 0.224
regulation of monocyte chemotaxis GO:0090025 3 0.223
leukocyte migration GO:0050900 124 0.219
Human Mouse Rat
leukocyte mediated immunity GO:0002443 174 0.212
Mouse
t cell differentiation GO:0030217 174 0.211
organic cyclic compound catabolic process GO:1901361 295 0.211
cellular nitrogen compound catabolic process GO:0044270 280 0.209
lymphocyte differentiation GO:0030098 242 0.206
lymphocyte activation involved in immune response GO:0002285 93 0.199
homeostasis of number of cells GO:0048872 210 0.197
Mouse
leukocyte differentiation GO:0002521 342 0.196
organonitrogen compound catabolic process GO:1901565 264 0.195
cytokine production involved in immune response GO:0002367 34 0.193
positive regulation of myoblast differentiation GO:0045663 8 0.192
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.191
ribonucleoside catabolic process GO:0042454 206 0.188
purine ribonucleoside metabolic process GO:0046128 241 0.188
regulation of t helper 1 cell cytokine production GO:2000554 1 0.186
regulation of response to biotic stimulus GO:0002831 38 0.181
Mouse
heterocycle catabolic process GO:0046700 280 0.177
organophosphate catabolic process GO:0046434 232 0.176
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.175
muscle cell development GO:0055001 133 0.175
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.174
immunoglobulin production in mucosal tissue GO:0002426 3 0.173
positive regulation of lymphocyte activation GO:0051251 140 0.172
innate immune response activating signal transduction GO:0002758 50 0.171
cytoplasmic transport GO:0016482 234 0.171
Human
negative regulation of viral genome replication GO:0045071 10 0.171
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.169
positive regulation of eosinophil migration GO:2000418 2 0.167
positive regulation of cell activation GO:0050867 158 0.166
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.165
regulation of myoblast differentiation GO:0045661 29 0.160
leukocyte proliferation GO:0070661 172 0.156
nucleoside triphosphate catabolic process GO:0009143 205 0.156
t cell differentiation involved in immune response GO:0002292 30 0.152
purine ribonucleotide metabolic process GO:0009150 290 0.151
Human
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.151
purine nucleotide catabolic process GO:0006195 211 0.150
endocytosis GO:0006897 168 0.148
immune response activating signal transduction GO:0002757 116 0.148
purine containing compound catabolic process GO:0072523 213 0.146
carbohydrate derivative catabolic process GO:1901136 231 0.145
alpha beta t cell activation GO:0046631 91 0.144
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.140
positive regulation of t cell activation GO:0050870 101 0.140
ribonucleoside metabolic process GO:0009119 245 0.139
glycosyl compound catabolic process GO:1901658 206 0.139
t helper cell differentiation GO:0042093 28 0.138
positive regulation of programmed cell death GO:0043068 218 0.137
regulation of eosinophil migration GO:2000416 2 0.136
nucleoside metabolic process GO:0009116 246 0.134
negative regulation of cell proliferation GO:0008285 296 0.134
regulation of protein localization GO:0032880 231 0.134
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.133
interleukin 1 production GO:0032612 31 0.133
purine containing compound metabolic process GO:0072521 311 0.133
Human
alpha beta t cell differentiation GO:0046632 69 0.132
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.130
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.129
Mouse
regulation of inflammatory response GO:0050727 147 0.128
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.128
t helper 1 cell cytokine production GO:0035744 1 0.126
protein localization to organelle GO:0033365 185 0.125
regulation of cellular response to stress GO:0080135 159 0.125
regulation of neutrophil mediated killing of fungus GO:0070953 1 0.123
Mouse
epithelial tube morphogenesis GO:0060562 303 0.122
metal ion homeostasis GO:0055065 189 0.122
Human
response to organic cyclic compound GO:0014070 198 0.120
Rat
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.119
Mouse
b cell mediated immunity GO:0019724 71 0.117
nucleoside triphosphate metabolic process GO:0009141 230 0.116
cellular chemical homeostasis GO:0055082 215 0.115
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.114
immunoglobulin mediated immune response GO:0016064 69 0.112
dendritic cell dendrite assembly GO:0097026 2 0.111
nucleoside phosphate catabolic process GO:1901292 222 0.111
cellular response to interferon alpha GO:0035457 4 0.111
positive regulation of neutrophil mediated killing of fungus GO:0070965 1 0.109
Mouse
positive regulation of interferon alpha production GO:0032727 4 0.109
negative regulation of myoblast differentiation GO:0045662 18 0.108
positive regulation of interleukin 12 production GO:0032735 21 0.108
nucleoside catabolic process GO:0009164 206 0.108
dendritic cell differentiation GO:0097028 26 0.108
regulation of muscle tissue development GO:1901861 97 0.107
regulation of lymphocyte activation GO:0051249 240 0.105
negative regulation of macrophage apoptotic process GO:2000110 3 0.105
negative regulation of phosphate metabolic process GO:0045936 184 0.105
muscle tissue development GO:0060537 308 0.104
guanosine containing compound metabolic process GO:1901068 144 0.103
positive regulation of monocyte chemotaxis GO:0090026 2 0.103
viral life cycle GO:0019058 36 0.101
skeletal muscle organ development GO:0060538 163 0.101
t helper 17 cell lineage commitment GO:0072540 4 0.101
purine nucleoside catabolic process GO:0006152 205 0.101
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.101
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.101
ribose phosphate metabolic process GO:0019693 291 0.100
Human
purine nucleoside triphosphate metabolic process GO:0009144 226 0.099
cd4 positive alpha beta t cell activation GO:0035710 45 0.098
regulation of establishment of protein localization GO:0070201 181 0.098
regulation of skeletal muscle fiber development GO:0048742 36 0.098
lymphocyte proliferation GO:0046651 164 0.097
gtp catabolic process GO:0006184 143 0.096
establishment of protein localization to organelle GO:0072594 118 0.096
ribonucleoside triphosphate catabolic process GO:0009203 199 0.095
positive regulation of adaptive immune response GO:0002821 61 0.095
guanosine containing compound catabolic process GO:1901069 144 0.095
lymphocyte mediated immunity GO:0002449 139 0.093
positive regulation of hematopoietic stem cell proliferation GO:1902035 2 0.093
Mouse
cytokine biosynthetic process GO:0042089 68 0.093
t cell proliferation GO:0042098 120 0.093
mapk cascade GO:0000165 281 0.093
nucleotide metabolic process GO:0009117 332 0.091
Human
type i interferon production GO:0032606 29 0.091
regulation of mapk cascade GO:0043408 248 0.089
purine ribonucleotide catabolic process GO:0009154 208 0.089
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.088
negative regulation of phosphorus metabolic process GO:0010563 184 0.088
calcium ion transport GO:0006816 159 0.088
Human
regulation of kinase activity GO:0043549 249 0.088
regulation of cytokine biosynthetic process GO:0042035 59 0.088
regulation of killing of cells of other organism GO:0051709 4 0.088
Mouse
negative regulation of molecular function GO:0044092 258 0.086
purine nucleoside metabolic process GO:0042278 241 0.085
intracellular protein transport GO:0006886 204 0.085
purine nucleoside triphosphate catabolic process GO:0009146 203 0.085
immune response regulating signaling pathway GO:0002764 125 0.084
regulation of cell killing GO:0031341 40 0.083
Mouse
regulation of adaptive immune response GO:0002819 90 0.083
sequestering of calcium ion GO:0051208 18 0.083
negative regulation of viral process GO:0048525 23 0.083
positive regulation of mapk cascade GO:0043410 170 0.083
thymocyte migration GO:0072679 2 0.083
nucleobase containing small molecule metabolic process GO:0055086 352 0.083
Human
cation homeostasis GO:0055080 212 0.082
Human
gtp metabolic process GO:0046039 144 0.082
nucleotide catabolic process GO:0009166 217 0.082
regulation of cellular ketone metabolic process GO:0010565 66 0.082
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.081
positive regulation of thymocyte migration GO:2000412 2 0.081
regulation of interferon alpha production GO:0032647 5 0.081
reactive oxygen species metabolic process GO:0072593 84 0.080
Mouse
t cell costimulation GO:0031295 14 0.080
interferon gamma production GO:0032609 67 0.079
inflammatory response GO:0006954 244 0.079
Mouse
aromatic compound catabolic process GO:0019439 286 0.079
natural killer cell chemotaxis GO:0035747 1 0.079
regulation of myotube differentiation GO:0010830 62 0.079
regulation of interferon gamma production GO:0032649 57 0.079
positive regulation of type 2 immune response GO:0002830 9 0.078
ribonucleoside triphosphate metabolic process GO:0009199 220 0.078
protein import GO:0017038 101 0.078
mature dendritic cell differentiation GO:0097029 3 0.078
calcium ion homeostasis GO:0055074 127 0.078
Human
myeloid cell homeostasis GO:0002262 114 0.077
hematopoietic stem cell proliferation GO:0071425 13 0.077
Mouse
neutrophil migration GO:1990266 37 0.077
Mouse
mammary gland epithelium development GO:0061180 65 0.077
regulation of thymocyte migration GO:2000410 2 0.077
regulation of cell activation GO:0050865 289 0.076
nucleoside phosphate metabolic process GO:0006753 338 0.076
Human
eosinophil migration GO:0072677 3 0.075
divalent inorganic cation homeostasis GO:0072507 138 0.075
Human
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.075
regulation of cell motility GO:2000145 236 0.075
Human Rat
protein localization to nucleus GO:0034504 121 0.074
regulation of cytokine production involved in immune response GO:0002718 26 0.073
cellular response to organic cyclic compound GO:0071407 87 0.073
cation transport GO:0006812 399 0.073
Human
macromolecule catabolic process GO:0009057 281 0.073
regulation of cell migration GO:0030334 219 0.072
Human Rat
negative regulation of immune system process GO:0002683 209 0.072
gland development GO:0048732 330 0.070
regulation of protein kinase activity GO:0045859 232 0.070
regulation of growth of symbiont in host GO:0044126 19 0.070
regulation of leukocyte proliferation GO:0070663 121 0.069
regulation of neutrophil mediated killing of bacterium GO:0070950 1 0.069
Mouse
positive regulation of protein modification process GO:0031401 299 0.068
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.067
purine ribonucleoside catabolic process GO:0046130 205 0.067
myotube differentiation GO:0014902 105 0.067
regulation of secretion by cell GO:1903530 249 0.067
tumor necrosis factor production GO:0032640 50 0.066
regulation of b cell chemotaxis GO:2000537 2 0.066
striated muscle tissue development GO:0014706 293 0.066
response to organonitrogen compound GO:0010243 246 0.065
b cell chemotaxis GO:0035754 3 0.064
negative regulation of phosphorylation GO:0042326 166 0.064
positive regulation of protein phosphorylation GO:0001934 242 0.064
i kappab kinase nf kappab signaling GO:0007249 85 0.064
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.064
regulation of leukocyte differentiation GO:1902105 159 0.064
reactive oxygen species biosynthetic process GO:1903409 8 0.064
interleukin 12 secretion GO:0072610 3 0.064
regulation of lymphocyte proliferation GO:0050670 117 0.063
regulation of striated muscle cell differentiation GO:0051153 81 0.063
myeloid cell apoptotic process GO:0033028 22 0.063
protein import into nucleus GO:0006606 95 0.062
sequestering of metal ion GO:0051238 19 0.062
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.061
striated muscle cell development GO:0055002 125 0.061
negative regulation of protein modification process GO:0031400 163 0.060
positive regulation of leukocyte differentiation GO:1902107 86 0.060
b cell activation involved in immune response GO:0002312 50 0.060
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.060
glycoprotein metabolic process GO:0009100 116 0.059
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.059
Mouse
protein catabolic process GO:0030163 221 0.059
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.059
Human
positive regulation of jun kinase activity GO:0043507 30 0.058
lymphocyte chemotaxis GO:0048247 10 0.058
Human
anion transport GO:0006820 177 0.058
muscle cell differentiation GO:0042692 261 0.057
type 2 immune response GO:0042092 23 0.057
protein secretion GO:0009306 111 0.057
Rat
regulation of type 2 immune response GO:0002828 18 0.057
positive regulation of interferon gamma production GO:0032729 39 0.056
astrocyte cell migration GO:0043615 3 0.056
regulation of natural killer cell chemotaxis GO:2000501 1 0.056
morphogenesis of a branching structure GO:0001763 203 0.056
regulation of t cell mediated immunity GO:0002709 34 0.056
positive regulation of b cell chemotaxis GO:2000538 2 0.056
protein modification by small protein conjugation or removal GO:0070647 207 0.055
positive regulation of acute inflammatory response GO:0002675 16 0.055
cellular ketone metabolic process GO:0042180 84 0.055
myoblast differentiation GO:0045445 52 0.055
regulation of homeostatic process GO:0032844 182 0.055
Human
cellular response to dna damage stimulus GO:0006974 207 0.054
regulation of dendritic cell dendrite assembly GO:2000547 2 0.054
regulation of protein serine threonine kinase activity GO:0071900 157 0.054
regulation of transferase activity GO:0051338 263 0.054
positive regulation of kinase activity GO:0033674 155 0.054
regulation of production of molecular mediator of immune response GO:0002700 65 0.054
regulation of t helper 1 cell differentiation GO:0045625 7 0.054
response to interleukin 4 GO:0070670 23 0.053
skeletal muscle fiber development GO:0048741 58 0.053
regulation of secretion GO:0051046 274 0.053
regulation of hydrolase activity GO:0051336 246 0.052
reactive nitrogen species metabolic process GO:2001057 0 0.052
ribonucleotide metabolic process GO:0009259 291 0.052
Human
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.052
regulation of antimicrobial humoral response GO:0002759 3 0.051
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.051
regulation of defense response to virus GO:0050688 18 0.051
positive regulation of map kinase activity GO:0043406 84 0.050
positive regulation of cytokine production involved in immune response GO:0002720 19 0.050
glycoprotein biosynthetic process GO:0009101 89 0.050
cellular amine metabolic process GO:0044106 44 0.050
ossification GO:0001503 216 0.050
leukocyte apoptotic process GO:0071887 71 0.050
antigen processing and presentation GO:0019882 47 0.050
regulation of lymphocyte differentiation GO:0045619 107 0.049
regulation of defense response to fungus GO:1900150 1 0.049
Mouse
negative regulation of lipid metabolic process GO:0045833 30 0.049
toll like receptor signaling pathway GO:0002224 38 0.049
myeloid leukocyte activation GO:0002274 83 0.049
positive regulation of cellular amine metabolic process GO:0033240 5 0.049
carbohydrate derivative biosynthetic process GO:1901137 183 0.049
autophagy GO:0006914 45 0.049
regulation of response to wounding GO:1903034 189 0.049
regulation of cytoplasmic transport GO:1903649 112 0.049
Human
regulation of protein targeting GO:1903533 61 0.048
cytokine metabolic process GO:0042107 71 0.048
cholesterol metabolic process GO:0008203 56 0.047
regulation of neutrophil mediated cytotoxicity GO:0070948 2 0.047
Mouse
regulation of protein secretion GO:0050708 82 0.047
protein ubiquitination GO:0016567 171 0.047
regulation of t cell proliferation GO:0042129 92 0.046
cell recognition GO:0008037 83 0.046
cellular homeostasis GO:0019725 240 0.046
Human
regulation of nucleotide metabolic process GO:0006140 169 0.046
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.046
positive regulation of leukocyte mediated immunity GO:0002705 70 0.046
Mouse
regulation of tumor necrosis factor production GO:0032680 49 0.046
sterol metabolic process GO:0016125 58 0.046
alpha beta t cell proliferation GO:0046633 21 0.045
single organism nuclear import GO:1902593 95 0.045
myotube cell development GO:0014904 60 0.045
nuclear transport GO:0051169 139 0.045
positive regulation of muscle cell differentiation GO:0051149 39 0.045
Mouse
rho protein signal transduction GO:0007266 32 0.044
nucleocytoplasmic transport GO:0006913 139 0.044
negative regulation of defense response to virus by host GO:0050689 1 0.044
regulation of cellular component biogenesis GO:0044087 181 0.044
regulation of ion transport GO:0043269 215 0.044
Human
regulation of acute inflammatory response GO:0002673 27 0.044
cytokine secretion GO:0050663 72 0.044
growth of symbiont involved in interaction with host GO:0044116 23 0.043
positive regulation of t cell differentiation GO:0045582 52 0.043
acute inflammatory response GO:0002526 41 0.043
nuclear import GO:0051170 95 0.043
regulation of defense response to virus by host GO:0050691 8 0.043
cellular amino acid metabolic process GO:0006520 103 0.042
muscle fiber development GO:0048747 76 0.042
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.042
stress activated mapk cascade GO:0051403 80 0.042
ribonucleotide catabolic process GO:0009261 208 0.042
regulation of interleukin 1 production GO:0032652 26 0.042
purine nucleotide metabolic process GO:0006163 302 0.042
Human
positive regulation of alpha beta t cell activation GO:0046635 39 0.042
positive regulation of protein kinase activity GO:0045860 144 0.042
t cell mediated immunity GO:0002456 50 0.042
epithelial cell proliferation GO:0050673 174 0.041
positive regulation of jnk cascade GO:0046330 46 0.041
maintenance of location GO:0051235 89 0.041
regulation of type i interferon production GO:0032479 22 0.041
skin development GO:0043588 220 0.041
cell type specific apoptotic process GO:0097285 268 0.040
granulocyte chemotaxis GO:0071621 39 0.040
Mouse
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 10 0.039
extrinsic apoptotic signaling pathway GO:0097191 126 0.039
positive regulation of secretion GO:0051047 130 0.039
b cell activation GO:0042113 161 0.038
negative regulation of defense response GO:0031348 77 0.038
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.038
Mouse
regulation of stress activated mapk cascade GO:0032872 69 0.038
positive regulation of cell killing GO:0031343 33 0.038
Mouse
positive regulation of antimicrobial humoral response GO:0002760 2 0.038
membrane organization GO:0061024 245 0.038
mature natural killer cell chemotaxis GO:0035782 1 0.038
chemokine production GO:0032602 34 0.038
Mouse
regulation of hormone levels GO:0010817 211 0.038
growth involved in symbiotic interaction GO:0044110 23 0.037
regulation of lymphocyte mediated immunity GO:0002706 84 0.037
antimicrobial peptide production GO:0002775 2 0.037
regulation of alpha beta t cell proliferation GO:0046640 18 0.037
regulation of membrane potential GO:0042391 192 0.037
negative regulation of muscle cell differentiation GO:0051148 33 0.037
amine metabolic process GO:0009308 45 0.037
angiogenesis GO:0001525 201 0.037
Rat
regulation of intracellular protein transport GO:0033157 82 0.036
organic acid transport GO:0015849 101 0.036
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.036
toll like receptor 7 signaling pathway GO:0034154 4 0.036
jnk cascade GO:0007254 72 0.036
positive regulation of t cell mediated immunity GO:0002711 24 0.036
regulation of chemokine production GO:0032642 30 0.036
Mouse
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.036
regulation of ossification GO:0030278 112 0.035
antimicrobial peptide biosynthetic process GO:0002777 2 0.035
protein modification by small protein conjugation GO:0032446 187 0.035
t helper 1 type immune response GO:0042088 25 0.035
regulation of hematopoietic stem cell proliferation GO:1902033 3 0.035
Mouse
negative regulation of protein transport GO:0051224 46 0.035
negative regulation of protein phosphorylation GO:0001933 126 0.034
leukocyte mediated cytotoxicity GO:0001909 62 0.034
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.034
negative regulation of innate immune response GO:0045824 17 0.034
positive regulation of leukocyte proliferation GO:0070665 73 0.034
positive regulation of stress activated mapk cascade GO:0032874 48 0.034
regulation of autophagy GO:0010506 30 0.033
activation of immune response GO:0002253 138 0.033
protein targeting GO:0006605 143 0.033
lymphocyte migration GO:0072676 26 0.033
Human
positive regulation of cellular component biogenesis GO:0044089 94 0.033
regulation of nucleocytoplasmic transport GO:0046822 73 0.033
regulation of cell projection assembly GO:0060491 38 0.033
regulation of organelle organization GO:0033043 289 0.033
apoptotic signaling pathway GO:0097190 306 0.033
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.033
positive regulation of lymphocyte proliferation GO:0050671 70 0.033
positive regulation of lymphocyte differentiation GO:0045621 61 0.033
positive regulation of chemotaxis GO:0050921 38 0.032
Rat
regulation of alpha beta t cell activation GO:0046634 53 0.032
phagocytosis GO:0006909 66 0.032
positive regulation of myotube differentiation GO:0010831 24 0.032
Mouse
negative regulation of growth of symbiont in host GO:0044130 19 0.032
carbohydrate metabolic process GO:0005975 230 0.032
cytosolic calcium ion homeostasis GO:0051480 70 0.032
Human
interferon beta biosynthetic process GO:0045350 4 0.032
stress activated protein kinase signaling cascade GO:0031098 81 0.032
positive regulation of cell motility GO:2000147 116 0.031
Human Rat
t cell chemotaxis GO:0010818 6 0.031
Human
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.031
cellular response to growth factor stimulus GO:0071363 197 0.031
regulation of purine nucleotide catabolic process GO:0033121 122 0.031
organ or tissue specific immune response GO:0002251 13 0.031
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.030
mammary gland duct morphogenesis GO:0060603 38 0.030
regulation of protein localization to nucleus GO:1900180 60 0.030
small gtpase mediated signal transduction GO:0007264 97 0.030
response to tumor necrosis factor GO:0034612 26 0.030
response to radiation GO:0009314 165 0.030
Rat
positive regulation of inflammatory response GO:0050729 47 0.030
regulation of cytokine secretion GO:0050707 61 0.030
t helper 1 cell differentiation GO:0045063 13 0.030
response to ionizing radiation GO:0010212 42 0.029
Rat
regulation of angiogenesis GO:0045765 81 0.029
Rat
divalent metal ion transport GO:0070838 172 0.029
Human
positive regulation of neuron apoptotic process GO:0043525 25 0.029
positive regulation of response to wounding GO:1903036 66 0.029
myeloid leukocyte migration GO:0097529 57 0.029
Mouse
peptidyl amino acid modification GO:0018193 336 0.029
positive regulation of transferase activity GO:0051347 167 0.029
positive regulation of hydrolase activity GO:0051345 148 0.029
wound healing involved in inflammatory response GO:0002246 4 0.029
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.029
interleukin 1 secretion GO:0050701 16 0.029
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.029
negative regulation of hydrolase activity GO:0051346 71 0.029
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.029
natural killer cell mediated cytotoxicity GO:0042267 29 0.029
organic anion transport GO:0015711 137 0.028
regulation of t cell differentiation GO:0045580 83 0.028
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.028
positive regulation of t cell proliferation GO:0042102 52 0.028
response to dsrna GO:0043331 30 0.028
response to type i interferon GO:0034340 12 0.028
cellular response to type i interferon GO:0071357 10 0.028
glucose transport GO:0015758 56 0.028
cellular response to organonitrogen compound GO:0071417 145 0.028
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.027
cellular response to interleukin 4 GO:0071353 21 0.027
peptide secretion GO:0002790 114 0.027
syncytium formation by plasma membrane fusion GO:0000768 42 0.027
ras protein signal transduction GO:0007265 77 0.027
immunoglobulin production GO:0002377 73 0.027
t cell extravasation GO:0072683 4 0.027
lipid localization GO:0010876 126 0.027
regulation of cdc42 protein signal transduction GO:0032489 5 0.027
cellular macromolecule catabolic process GO:0044265 206 0.026
response to molecule of fungal origin GO:0002238 4 0.026
regulation of map kinase activity GO:0043405 120 0.026
growth of symbiont in host GO:0044117 23 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
rig i signaling pathway GO:0039529 4 0.026
cellular metal ion homeostasis GO:0006875 151 0.026
Human
killing by host of symbiont cells GO:0051873 11 0.026
Mouse

Cxcl10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.048
cancer DOID:162 0 0.044
gastrointestinal system cancer DOID:3119 0 0.036
organ system cancer DOID:0050686 0 0.036